beta IV Tubulin (TUBB4A) (NM_006087) Human Untagged Clone

CAT#: SC116314

TUBB4A (untagged)-Human tubulin, beta 4 (TUBB4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TUBB4A
• Synonyms: beta-5; DYT4; TUBB4
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116314 sequence for NM_006087 edited (data generated by NextGen Sequencing)
  ATGCGGGAGATCGTGCACCTGCAGGCCGGCCAGTGCGGCAACCAGATCGGGGCCAAGTTT
  TGGGAGGTTATCAGTGACGAACATGGCATCGACCCCACAGGCACATACCATGGGGACAGT
  GACCTGCAACTGGAGAGGATCAACGTGTACTACAACGAGGCCACAGGAGGAAATTATGTC
  CCCAGAGCGGTGCTGGTGGACCTGGAACCCGGCACCATGGACTCTGTCCGTTCTGGCCCC
  TTCGGTCAGATCTTTCGGCCGGACAACTTCGTGTTTGGCCAATCCGGAGCCGGCAACAAC
  TGGGCAAAGGGGCACTACACGGAGGGCGCAGAGCTGGTGGACGCTGTCCTGGACGTAGTC
  CGGAAGGAGGCCGAGAGCTGCGACTGCCTTCAGGGCTTCCAGCTGACCCACTCGCTGGGG
  GGTGGCACGGGGTCCGGAATGGGCACGCTGCTCATCAGTAAGATCCGCGAGGAGTTCCCA
  GACCGCATCATGAACACCTTCAGCGTGGTGCCCTCGCCCAAAGTGTCAGACACGGTGGTG
  GAGCCCTACAACGCCACGCTGTCTGTGCACCAGCTGGTGGAGAATACGGATGAGACCTAC
  TGCATCGACAACGAGGCACTCTACGACATCTGTTTCCGCACCCTCAAGCTGACCACCCCC
  ACCTACGGGGACCTCAACCACCTGGTGTCGGCCACCATGAGCGGGGTCACCACCTGCCTG
  CGCTTCCCGGGCCAGCTGAACGCCGACCTGCGCAAGCTGGCCGTCAACATGGTCCCCTTT
  CCTCGCCTGCACTTCTTCATGCCCGGCTTCGCACCCCTGACCAGCCGGGGCAGCCAGCAG
  TACCGGGCCCTGACGGTGCCCGAGCTCACCCAGCAGATGTTCGATGCCAAGAACATGATG
  GCGGCGTGCGACCCGCGCCACGGCCGCTACCTGACCGTGGCCGCCGTGTTCCGGGGCCGC
  ATGTCCATGAAGGAGGTGGACGAGCAGATGCTGAGCGTGCAGAGCAAGAACAGCAGCTAC
  TTCGTGGAGTGGATCCCCAACAACGTGAAGACGGCCGTGTGCGACATCCCGCCCCGCGGC
  CTGAAGATGGCCGCGACCTTCATCGGCAACAGCACGGCCATCCAGGAGCTGTTCAAGCGC
  ATCTCCGAGCAGTTCACGGCCATGTTCCGGCGCAAGGCCTTCTTGCACTGGTACACGGGC
  GAGGGCATGGACGAGATGGAGTTCACCGAGGCCGAGAGCAACATGAATGACCTGGTATCT
  GAGTACCAGCAGTACCAGGACGCCACGGCCGAGGAGGGCGAGTTCGAGGAGGAGGCGGAG
  GAGGAGGTGGCCTAG
  
  Clone variation with respect to NM_006087.2
  774 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006087 unedited
  NGGGGAGTCGGGATTTGTAACCGACTCATATAGGCGGAACGCCAATTCGCACGAGGGGAG
  GGTGACCGGCCGTGACGCGTGCCCCGCCCGCTCATGGAGCGGCTCCCGGGGGCGCAGGGG
  CCGTGCTCCGCCGTCTCCGCCGCATCTTCCACCCTCGCCGCCGCCGCAGCTCCCCGCGCT
  CGTGCCACCGCCGCCGCGTCCACCCTCAGCGCTTTCTTCTGCGGGAGATCGTGCACCTGC
  GGGGGGGCCANTGCGGCGACCAGATCGGGGCCAAGTTTTGGGAGGTGAGGAGTGACGAAC
  ATGGCATCGGCCCCACAGGCACATACCATGGGGACAGTGACCTGGAACTGGAGAGGATCA
  ACGTGTACTACAACGAGGCCACAGGAGGAAATTATGTGCCCCAGAGCGGTGCTGGTGGAC
  CTGGAACCCGGCACCATGGACTCTGTGCCGTGTCTGGCCCCTTCGGTCAGATCTTTCGGG
  CGGACAACTTCGTGTTTGGCCAATCCGGAGCCGGCGACAACTGGGCAAAGGGGCACTACA
  CGGAGGGCGCANAGCTGGTGGACGCTGTCCTGGACGTANTCCGGAAGGAGGCCGAGAGCT
  GCGACTGGCTTCAGGGCTTCCAGCTGACCCACTCGCTGGGGGGTGGCACGGGGTCCGGGA
  TGGCACGCTGCTCATCAGTAAGATCCGCGAGGAGTTCCCAGACCGCATCATGAACACCTT
  CAGCGTGGTGCCCTCGCCCAAAGTGTCAGACACGGTGGGTGGAGCCCCTACACGCCCCGC
  TGTCTGTGCACCAGCGTGGGGGAGAAACNGGTGAGACCTACTGCATCGACAACGAGGCGC
  TCTACGACATCTGTGTCCGCACCCTCAAGCTGACCACCCCACCTACGGGGACCTAACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006087 unedited
  CCCCCNNCCCTTTGCTTGGACCCGGCCGCATCTAAGATCGATTTTTTTTTTTTTTTTTTT
  CCATGACAACAATTAATTTATTTATTGAGGGTGAGGCAGGCAAGCGGGGAGGGAGGGTAG
  GGGTGACCTCTCTTCCTCACAGGCACCAGGCCTTGTTTCTCTCCCAGAAAGCTAAGGCCG
  GCAGGGGCTGACGGGAGTGAGGCAGGGAGGATGCATGGGGCCTGTGGGAACCCAGAGAGA
  AGCTGGGGTCAGAGGACGCACCTCCCCCTGGGGGGCGCGGCGGCCAATATTTCTCCCCCC
  AACTATATTTTTCTAATTTTCAATCCTAATTTTCTCCCACCATCCTTCTCCCACCCACCC
  CCCCCCCCCCCCCCCCCCCACTTCTCCCCCCCCATACTCCCCCCCCCCACGCCCCTACCC
  AATCCCTCCTCCCCCCATCACCCCCTCTACTTCCCCCCTCTACCTACTACCCCCCCCTCC
  CCACTTCAACCTCCCCCCTCCCCTCCTCACCCTTTCATCACCCTCCCCTTTTTCTCCCAT
  AACCCCCTTTTCCCTCTCCCCTCCTCTCTTACTTCCCTCCCTCCCCCCCCCCAACCCCCC
  CCTATCTCCCCCTCACCCTTCTCTTCATTTTTTCCTTCCCCCCCTCCCCACTCCCACCCT
  CCTCTCCCTCTTTTACCTTTTTCCTTCCCACCCCCACTATTCCACCTTTTACTTACCTTC
  TCCTCCACACCCCCCCGTTTTCCACGTTCCCAAAACCTTCTCCCCCACCTCTTTCCTTCT
  TTTCCTCTCCACTACCCCTTTCCCTCCATACCTCCTCCTTTTCTCCCCCCACGCTCCTCC
  TCTTCCCTATAACCCCTATACCTCACCCCCGCCCTCTCATTCTCTTCCCCTTCCACATCC
  CTCATCTACCATCCCACCCCCC
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_006087
• ORF Size: 1335 bp
• Insert Size: 2440
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006087.2, NP_006078.2
• RefSeq Size: 2318
• RefSeq ORF: 1335
• Locus ID: 10382
• Domains: tubulin
• Protein Families: Druggable Genome
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection
• Gene Summary: This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (3) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Both variants 3 and 4 encode the same isoform 3.