beta IV Tubulin (TUBB4A) (NM_006087) Human Untagged Clone

CAT#: SC323934

TUBB4A (untagged)-Human tubulin, beta 4 (TUBB4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TUBB4A
• Synonyms: beta-5; DYT4; TUBB4
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006087.2 CGCAGGGACCGTGCTCCGCCGTCTCCGCCGCATCTTCCACCCTCGCCGCCGCCGCAGCTC
  CCCGCGCTCGTGCCACCGCCGCCGCGTCCACCCTCAGCGCCACCGCCATGCGGGAGATCG
  TGCACCTGCAGGCCGGCCAGTGCGGCAACCAGATCGGGGCCAAGTTTTGGGAGGTTATCA
  GTGACGAACATGGCATCGACCCCACAGGCACATACCATGGGGACAGTGACCTGCAACTGG
  AGAGGATCAACGTGTACTACAACGAGGCCACAGGAGGAAATTATGTCCCCAGAGCGGTGC
  TGGTGGACCTGGAACCCGGCACCATGGACTCTGTCCGTTCTGGCCCCTTCGGTCAGATCT
  TTCGGCCGGACAACTTCGTGTTTGGCCAATCCGGAGCCGGCAACAACTGGGCAAAGGGGC
  ACTACACGGAGGGCGCAGAGCTGGTGGACGCTGTCCTGGACGTAGTCCGGAAGGAGGCCG
  AGAGCTGCGACTGCCTTCAGGGCTTCCAGCTGACCCACTCGCTGGGGGGTGGCACGGGGT
  CCGGAATGGGCACGCTGCTCATCAGTAAGATCCGCGAGGAGTTCCCAGACCGCATCATGA
  ACACCTTCAGCGTGGTGCCCTCGCCCAAAGTGTCAGACACGGTGGTGGAGCCCTACAACG
  CCACGCTGTCTGTGCACCAGCTGGTGGAGAATACGGATGAGACCTACTGCATCGACAACG
  AGGCACTCTACGACATCTGTTTCCGCACCCTCAAGCTGACCACCCCCACCTACGGGGACC
  TCAACCACCTGGTGTCGGCCACCATGAGCGGGGTCACCACCTGCCTGCGCTTCCCGGGCC
  AGCTGAACGCCGACCTGCGCAAGCTGGCCGTCAACATGGTTCCCTTTCCTCGCCTGCACT
  TCTTCATGCCCGGCTTCGCACCCCTGACCAGCCGGGGCAGCCAGCAGTACCGGGCCCTGA
  CGGTGCCCGAGCTCACCCAGCAGATGTTCGATGCCAAGAACATGATGGCGGCGTGCGACC
  CGCGCCACGGCCGCTACCTGACCGTGGCCGCCGTGTTCCGGGGCCGCATGTCCATGAAGG
  AGGTGGACGAGCAGATGCTGAGCGTGCAGAGCAAGAACAGCAGCTACTTCGTGGAGTGGA
  TCCCCAACAACGTGAAGACGGCCGTGTGCGACATCCCGCCCCGCGGCCTGAAGATGGCCG
  CGACCTTCATCGGCAACAGCACGGCCATCCAGGAGCTGTTCAAGCGCATCTCCGAGCAGT
  TCACGGCCATGTTCCGGCGCAAGGCCTTCTTGCACTGGTACACGGGCGAGGGCATGGACG
  AGATGGAGTTCACCGAGGCCGAGAGCAACATGAATGACCTGGTATCTGAGTACCAGCAGT
  ACCAGGACGCCACGGCCGAGGAGGGCGAGTTCGAGGAGGAGGCGGAGGAGGAGGTGGCCT
  AGGCTGCTCCCATCGCTTCCCACCTGTCCCCTCGAGGCTTCTGACCTTTGATCCGCTAGG
  CCCCCCATCTCTGAACCCTAGAGCCCCGCTTTCCCTCCAAGGCTGACTCCCCGCTGACCC
  TAACAATACCTTTGGAGCTCGCTTTACCTCTGGCTACTTCATCTCCGACCCTGGCTCCCC
  TTTGAGCCCTAATTTATCTTTAACCCCCTTGAGCTCTTCCAACCTTGACATTCCCAGGAG
  GAGCCCCGCTTCACCCCTTCTGACTCTGGAAACCGCACCTTTAACTTTGCAGACCTTCCT
  TCACCCCTGACTTCTGCTTCACCTTTGACCTCTGCCCCCCATGAATCCCATTTTACCTCT
  AGACCTATAAGTTCTGGTTTATGTTTGACCCCTCCCTCTGAGCTGCACTTCACCGCTGAC
  CTTGCCTCACCTTTAACCCCCCACCTGAGCCCCAGCTCCTACCTCTGACCCCAACTTCTC
  TTTGATCTCTGAATCCCCTCTGACTCCAACTTCTCTTTCACCCTCTATGAGTCCCATTTT
  ACTTCTACACCTGCAAGTCCTGGTTTATATTGGACCCCTCCCTCCGAGCTGCAGTTCACC
  TTTGACCTTGCCTCACCTTTCACCCCCCACCCCCCACAGCGTCAGCTCCTACCTCTGACC
  CCAGCTTCTCTCTGATTCCCACAGGCCCCATGCATCCTCCCTGCCTCACTCCCCTCAGCC
  CCTGCCGACCTTAGCTTATCTGGGAGAGAAACAAGGCCTGGTGCCTGTGAGGAAGAGAGG
  TCACCCCTACCCTCCCTCCCCGCTTCCCTGCCTCACCCTCAATAAATAAATTAATTGTTG
  TCATGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006087.2 unedited
  GGCCTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCGCAGGGACCGTGCTCCGCCGTCTCCG
  CCGCATCTTCCACCCTCGCCGCCGCCGCAGCTCCCCGCGCTCGTGCCACCGCCGCCGCGT
  CCACCCTCAGCGCCACCGCCATGCGGGAGATCGTGCACCTGCAGGCCGGCCAGTGCGGCA
  ACCAGATCGGGGCCAAGTTTTGGGAGGTTATCAGTGACGAACATGGCATCGACCCCACAG
  GCACATACCATGGGGACAGTGACCTGCAACTGGAGAGGATCAACGTGTACTACAACGAGG
  CCACAGGAGGAAATTATGTCCCCAGAGCGGTGCTGGTGGACCTGGAACCCGGCACCATGG
  ACTCTGTCCGTTCTGGCCCCTTCGGTCAGATCTTTCGGCCGGACAACTTCGTGTTTGGCC
  AATCCGGAGCCGGCAACAACTGGGCAAAGGGGCACTACACGGAGGGCGCAGAGCTGGTGG
  ACGCTGTCCTGGACGTAGTCCGGAAGGAGGCCGAGAGCTGCGACTGCCTTCAGGGCTTCC
  AGCTGACCCACTCGCTGGGGGGTGGCACGGGGTCCGGAATGGGCACGCTGCTCATCAGTA
  AGATCCGCGAGGAGTTCCCAGACCGCATCATGAACACCTTCAGCGTGGTGCCCTCGCCCA
  AAGTGTCAGACACGGTGGTGGAGCCCTACAACGCCACGCTGTCTGTGCCACCAGCTGGTG
  GAGAAATACGGATGAGACCTACTGCATCGACAACGAGGCCACTCTACGAACATCTGTTTC
  CGCACCCCTCAAGCTGACCACCCCCACCTACGGGGACTCACACCTGGTGGTCGCCACCAT
  GGAGCGGGGGTCACCACCTGCCTGGCGCCTTCCCGACCAGGCTGAACGCCGGACTGGGCA
  AGCTGGGCCGTTAAACAT
• Restriction Sites: ECoRI-NOT
• ACCN: NM_006087
• ORF Size: 1335 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006087.2, NP_006078.2
• RefSeq Size: 2318
• RefSeq ORF: 1335
• Locus ID: 10382
• Domains: tubulin
• Protein Families: Druggable Genome
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection
• Gene Summary: This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (3) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Both variants 3 and 4 encode the same isoform 3.