COMP (NM_000095) Human Untagged Clone
CAT#: SC116330
COMP (untagged)-Human cartilage oligomeric matrix protein (COMP)
"NM_000095" in other vectors (7)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | COMP |
Synonyms | EDM1; EPD1; MED; PSACH; THBS5; TSP5 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC116330 sequence for NM_000095 edited (data generated by NextGen Sequencing)
ATGGTCCCCGACACCGCCTGCGTTCTTCTGCTCACCCTGGCTGCCCTCGGCGCGTCCGGA CAGGGCCAGAGCCCGTTGGGCTCAGACCTGGGCCCGCAGATGCTTCGGGAACTGCAGGAA ACCAACGCGGCGCTGCAGGACGTGCGGGAGCTGCTGCGGCAGCAGGTCAGGGAGATCACG TTCCTGAAAAACACGGTGATGGAGTGTGACGCGTGCGGGATGCAGCAGTCAGTACGCACC GGCCTACCCAGCGTGCGGCCCCTGCTCCACTGCGCGCCCGGCTTCTGCTTCCCCGGCGTG GCCTGCATCCAGACGGAGAGCGGCGCGCGCTGCGGCCCCTGCCCCGCGGGCTTCACGGGC AACGGCTCGCACTGCACCGACGTCAACGAGTGCAACGCCCACCCCTGCTTCCCCCGAGTC CGCTGTATCAACACCAGCCCGGGGTTCCGCTGCGAGGCTTGCCCGCCGGGGTACAGCGGC CCCACCCACCAGGGCGTGGGGCTGGCTTTCGCCAAGGCCAACAAGCAGGTTTGCACGGAC ATCAACGAGTGTGAGACCGGGCAACATAACTGCGTCCCCAACTCCGTGTGCATCAACACC CGGGGCTCCTTCCAGTGCGGCCCGTGCCAGCCCGGCTTCGTGGGCGACCAGGCGTCCGGC TGCCAGCGGCGCGCACAGCGCTTCTGCCCCGACGGCTCGCCCAGCGAGTGCCACGAGCAT GCAGACTGCGTCCTAGAGCGCGATGGCTCGCGGTCGTGCGTGTGTGCCGTTGGCTGGGCC GGCAACGGGATCCTCTGTGGTCGCGACACTGACCTAGACGGCTTCCCGGACGAGAAGCTG CGCTGCCCGGAGCGCCAGTGCCGTAAGGACAACTGCGTGACTGTGCCCAACTCAGGGCAG GAGGATGTGGACCGCGATGGCATCGGAGACGCCTGCGATCCGGATGCCGACGGGGACGGG GTCCCCAATGAAAAGGACAACTGCCCGCTGGTGCGGAACCCAGACCAGCGCAACACGGAC GAGGACAAGTGGGGCGATGCGTGCGACAACTGCCGGTCCCAGAAGAACGACGACCAAAAG GACACAGACCAGGACGGCCGGGGCGATGCGTGCGACGACGACATCGACGGCGACCGGATC CGCAACCAGGCCGACAACTGCCCTAGGGTACCCAACTCAGACCAGAAGGACAGTGATGGC GATGGTATAGGGGATGCCTGTGACAACTGTCCCCAGAAGAGCAACCCGGATCAGGCGGAT GTGGACCACGACTTTGTGGGAGATGCTTGTGACAGCGATCAAGACCAGGATGGAGACGGA CATCAGGACTCTCGGGACAACTGTCCCACGGTGCCTAACAGTGCCCAGGAGGACTCAGAC CACGATGGCCAGGGTGATGCCTGCGACGACGACGACGACAATGACGGAGTCCCTGACAGT CGGGACAACTGCCGCCTGGTGCCTAACCCCGGCCAGGAGGACGCGGACAGGGACGGCGTG GGCGACGTGTGCCAGGACGACTTTGATGCAGACAAGGTGGTAGACAAGATCGACGTGTGT CCGGAGAACGCTGAAGTCACGCTCACCGACTTCAGGGCCTTCCAGACAGTCGTGCTGGAC CCGGAGGGTGACGCGCAGATTGACCCCAACTGGGTGGTGCTCAACCAGGGAAGGGAGATC GTGCAGACAATGAACAGCGACCCAGGCCTGGCTGTGGGTTACACTGCCTTCAATGGCGTG GACTTCGAGGGCACGTTCCATGTGAACACGGTCACGGATGACGACTATGCGGGCTTCATC TTTGGCTACCAGGACAGCTCCAGCTTCTACGTGGTCATGTGGAAGCAGATGGAGCAAACG TATTGGCAGGCGAACCCCTTCCGTGCTGTGGCCGAGCCTGGCATCCAACTCAAGGCTGTG AAGTCTTCCACAGGCCCCGGGGAACAGCTGCGGAACGCTCTGTGGCATACAGGAGACACA GAGTCCCAGGTGCGGCTGCTGTGGAAGGACCCGCGAAACGTGGGTTGGAAGGACAAGAAG TCCTATCGTTGGTTCCTGCAGCACCGGCCCCAAGTGGGCTACATCAGGGTGCGATTCTAT GAGGGCCCTGAGCTGGTGGCCGACAGCAACGTGGTCTTGGACACAACCATGCGGGGTGGC CGCCTGGGGGTCTTCTGCTTCTCCCAGGAGAACATCATCTGGGCCAACCTGCGTTACCGC TGCAATGACACCATCCCAGAGGACTATGAGACCCATCAGCTGCGGCAAGCCTAG Clone variation with respect to NM_000095.2 >OriGene 5' read for NM_000095 unedited
NGGGTTCAAATTAGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCCAGCT CCCCGCCACCGCCATGGTCCCCGACACCGCCTGCGTTCTTCTGCTCACCCTGGCTGCCCT CGGCGCGTCCGGACAGGGCCAGAGCCCGTTGGGCTCAGACCTGGGCCCGCAGATGCTTCG GGAACTGCAGGAAACCAACGCGGCGCTGCAGGACGTGCGGGAGCTGCTGCGGCAGCAGGT CAGGGAGATCACGTTCCTGAAAAACACGGTGATGGAGTGTGACGCGTGCGGGATGCAGCA GTCAGTACGCACCGGCCTACCCAGCGTGCGGCCCCTGCTCCACTGCGCGCCCGGCTTCTG CTTCCCCGGCGTGGCCTGCATCCAGACGGAGAGCGGCGCGCGCTGCGGCCCCTGCCCCGC GGGCTTCACGGGCAACGGCTCGCACTGCACCGACGTCAACGAGTGCAACGCCCACCCCTG CTTCCCCCGAGTCCGCTGTATCAACACCAGCCCGGGGTTCCGCTGCGAGGCTTGCCCGCC GGGGTACAGCGGCCCCACCCACCAGGGCGTGGGGCTGGCTTTCGCCAAGGCCAACAAGCA GGTTTGCACGGACATCAACGAGTGTGAGACCGGGCAACATAACTGCGTCCCCAACTCCGT GTGCATCAACACCCGGNGCTCCTTCCAGTGCGGCCCGTGCCAGCCCGGCTTCGTGGGCGA CCAGGCGTCCGGCTGCCAGCGGCGCGCACAGCGCTTCTGCCCCGACGGCTCGCCCAGCGA GTGCCACGAGCATGCAGACTGCGTCCTANAGCGCGATGGCTCGCGGTCGTGCGTGTGTGC CGTTGGGCTGGCCGCAACGGGATCCTCTGTGGTCGCGACACTGACCTANACGGCTTCCCG GACGAAAGCTGCGCTGCCCGGAGCGCAG >OriGene 3' read for NM_000095 unedited
GGAACTTCCGCACTTTNATTCTGTCCTCTCTGGACCCTTCTCACTTCCCCCTCAGGCGGC CACCCCTTGGGGCTGGGTGCAGAGCCCCCATCCAGCCGCGGTGAGGGTGGCTGTCATCCG GCGGGTCCTCACCCTGGTCCCTAGGCTTGCCGCAGCTGATGGGTCTCATAGTCCTCTGGG ATGGTGTCATTGCAGCGGTAACGCAGGTTGGCCCAGATGATGTTCTCCTGGGAGAAGCAG AAGACCCCCAGGCGGCCACCCCGCATGGTTGTGTCCAAGACCACGTTGCTGTCGGCCACC AGCTCAGGGCCCTCATAGAATCGCACCCTGATGTAGCCCACTTGGGGCCGGTGCTGCAGG AACCAACGATAGGACTTCTTGTCCTTCCAACCCACGTTTCGCGGGTCCTTCCACAGCAGC CGCACCTGGGACTCTGTGTCTCCTGTATGCCACAGAGCGTTCCGCAGCTGTTCCCCGGGG CCTGTGGAAGACTTCACAGCCTTGAGTTGGATGCCAGGCTCGGCCACAGCACGGAAGGGG TTCGCCTGCCAATACGTTTGCTCCATCTGCTTCCACATGACCACGTAGAAGCTGGAGCTG TCCTGGTAGCCAAAGATGAAGCCCGCATAGTCGTCATCCGTGACCGTGTTCACATGGAAC GTGCCCTCGAAGTCCACGCCATTGAAGGCAGTGTAACCCACAGCCAGCCCTGGGTCGCTG TTCATTGTCTGCACGATCTCCCTTCCCTGGTTGAACACCACCCATTGGGGTCAATCTGCG CGTTACCCTCCGGGTCCAACACCACTGTTTGGGAAGCCCCTGAAGTCGGTGAGCGTGACT TCAGCGTTTCTCCGACACACGTGATCTTGTGTACCACCTTNTCTGCATAAAATCGGCCCG GGACCCGTTGCCCAGCCCGTCCCGGACCGTACTA |
Restriction Sites | NotI-NotI |
ACCN | NM_000095 |
Insert Size | 2620 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000095.2, NP_000086.2 |
RefSeq Size | 2471 bp |
RefSeq ORF | 2274 bp |
Locus ID | 1311 |
Cytogenetics | 19p13.11 |
Domains | EGF_CA, tsp_3, EGF, EGF |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway |
Gene Summary | 'The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC324350 | COMP (untagged)-Human cartilage oligomeric matrix protein (COMP) |
USD 760.00 |
|
RC211080 | COMP (Myc-DDK-tagged)-Human cartilage oligomeric matrix protein (COMP) |
USD 420.00 |
|
RG211080 | COMP (GFP-tagged) - Human cartilage oligomeric matrix protein (COMP) |
USD 460.00 |
|
RC211080L1 | Lenti ORF clone of Human cartilage oligomeric matrix protein (COMP), Myc-DDK-tagged |
USD 768.00 |
|
RC211080L2 | Lenti ORF clone of Human cartilage oligomeric matrix protein (COMP), mGFP tagged |
USD 620.00 |
|
RC211080L3 | Lenti ORF clone of Human cartilage oligomeric matrix protein (COMP), Myc-DDK-tagged |
USD 620.00 |
|
RC211080L4 | Lenti ORF clone of Human cartilage oligomeric matrix protein (COMP), mGFP tagged |
USD 620.00 |
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