HS3ST3B1 (NM_006041) Human Untagged Clone

CAT#: SC116374

HS3ST3B1 (untagged)-Human heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 (HS3ST3B1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HS3ST3B1
• Synonyms: 3-OST-3B; 3OST3B1; h3-OST-3B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116374 sequence for NM_006041 edited (data generated by NextGen Sequencing)
  ATGGGGCAGCGCCTGAGTGGCGGCAGATCTTGCCTCGATGTCCCCGGCCGGCTCCTACCG
  CAGCCGCCGCCGCCCCCGCCGCCGGTGAGGAGGAAGCTCGCGCTGCTCTTCGCCATGCTC
  TGCGTCTGGCTCTATATGTTCCTGTACTCGTGCGCCGGCTCCTGCGCCGCCGCGCCGGGG
  CTGCTGCTCCTGGGCTCTGGGTCCCGCGCCGCACACGACCCGCCAGCCCTGGCCACAGCT
  CCGGACGGGACGCCCCCCAGGCTGCCGTTCCGGGCGCCGCCAGCCACCCCACTGGCTTCA
  GGCAAGGAGATGGCCGAGGGCGCTGCGAGCCCGGAGGAGCAGAGTCCCGAGGTGCCGGAC
  TCCCCAAGCCCCATCTCCAGCTTTTTCAGTGGGTCTGGGAGCAAGCAGCTGCCGCAGGCC
  ATCATCATCGGCGTGAAGAAGGGCGGCACGCGGGCGCTGCTGGAGTTTCTGCGCGTGCAC
  CCCGACGTGCGCGCCGTGGGCGCCGAGCCCCATTTCTTCGATCGCAGCTACGACAAGGGC
  CTCGCTTGGTACCGGGACCTGATGCCCAGAACCCTGGACGGGCAGATCACCATGGAGAAG
  ACGCCCAGTTACTTCGTCACGCGGGAGGCCCCCGCGCGCATCTCGGCCATGTCCAAGGAC
  ACCAAGCTCATCGTGGTGGTGCGGGACCCGGTGACCAGGGCCATCTCGGACTACACGCAG
  ACGCTGTCCAAGCGGCCCGACATCCCCACCTTCGAGAGCTTGACGTTCAAAAACAGGACA
  GCGGGCCTCATCGACACGTCGTGGAGCGCCATCCAGATCGGCATCTACGCCAAGCACCTG
  GAGCACTGGCTGCGCCACTTCCCCATCCGCCAGATGCTCTTCGTGAGCGGCGAGCGGCTC
  ATCAGCGACCCGGCCGGGGAGCTGGGCCGCGTGCAAGACTTCCTGGGCCTCAAGAGGATC
  ATCACGGACAAGCACTTCTACTTCAACAAGACCAAGGGCTTCCCCTGCCTGAAGAAGGCG
  GAGGGCAGCAGCCGGCCCCATTGCCTGGGCAAGACCAAGGGCAGGACCCATCCTGAGATC
  GACCGCGAGGTGGTGCGCAGGCTGCGCGAGTTCTACCGGCCTTTCAACCTCAAGTTCTAC
  CAGATGACCGGGCACGACTTTGGCTGGGATTGA
  
  Clone variation with respect to NM_006041.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006041 unedited
  ATTTTGTAATACGACTCACTATAGGGCGGCACGCGAATTCGCACGAGGGGAAGTGCCGGG
  GCTGCTCGAGGCTCATTTCTTATGACTGCAAGGAGGCAGCCCCGGCGTGCGGCGGTGCGC
  ACAGTCTATAGTGGCCAGGGCGCGAGAGTGCAACGTCCTCCTGGCCCCGAGCGCGTCGTC
  GCGCCCCGGGAGCAGACCCTCGCCCAGCAGTTACCGCCGTCCCGACTTTCCGTTCCAGTT
  GCAGCTCCTGCCGGGCAACATGTCAAGATCCGCCGCCGCTACAGCTGCCGCCGCCACCTG
  GGGAAGATCAGCAGCAGCAGCGGCGGCCGCGGGCACACGGGGGCAATAAACCGATCCACC
  CGGGCGTCCAGCGTGCCGGGGAACCCTCTCTGCGCTCACTGCCCGGCGGGACCCACGCCA
  TGTGCTGAGCCATGTCCCTGGCCGCGCCCGCGGGCAGCGCATGGGGCAGCGCCTGAGTGG
  CGGCAGATCTTGCCTCGATGTCCCCGGCCGGCTCCTACCGCAGCCGCCGCCGCCCCCGCC
  GCCGGTGAGGATGAAGCTCGCGCTGCTCTTCGCCATGCTCTGCGTCTGGCTCTATATGTT
  CCTGTACTCGTGCGCCGGCTCCTGCGCCGCCGCGCCGGGGCTGCTGCTCCTGAGCTCTGG
  GTCCCGCGCCGNACACGACCCGNCAGCCCTGGCCACAGCTNCGGACGGGACGCCCNCCAT
  GCTGNCGTTCCAGTCGCCGNCAGCCACCCCACTGGCTTCATGCATGGATATGGCCGATGG
  CGCTGCGAGCCCCGATGATCATAGTCCCGATGTGCCGGACTCCCCATGCCCATCTNCAGC
  TTTTTCATGGGGTCTGGGAGTCAGCAGCTGGCGCATGCCATCTCATTCGCGTGATTAATG
  GCGNACGCGGNCGCTGCTGNAGTTTTTGCGCGGCACCCCGACTGCGCCCGTGGTCGCGAG
  CCCATTTTTGGTTGCACTTCGATAGGCCTCCTTGGTCCGGNACTGATGCAAACCCGNACG
  GCGATACCATGGAATACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006041
• ORF Size: 1173 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006041.1, NP_006032.1
• RefSeq Size: 2032
• RefSeq ORF: 1173
• Locus ID: 9953
• Domains: Sulfotransfer
• Protein Families: Transmembrane
• Protein Pathways: Glycosaminoglycan degradation, Heparan sulfate biosynthesis
• Gene Summary: The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  Transcript Variant: This variant (1) represents the longer transcript. It encodes the protein.