HS3ST3B1 (NM_006041) Human Untagged Clone

CAT#: SC116374

HS3ST3B1 (untagged)-Human heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 (HS3ST3B1)


  "NM_006041" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol HS3ST3B1
Synonyms 3-OST-3B; 3OST3B1; h3-OST-3B
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC116374 sequence for NM_006041 edited (data generated by NextGen Sequencing)
ATGGGGCAGCGCCTGAGTGGCGGCAGATCTTGCCTCGATGTCCCCGGCCGGCTCCTACCG
CAGCCGCCGCCGCCCCCGCCGCCGGTGAGGAGGAAGCTCGCGCTGCTCTTCGCCATGCTC
TGCGTCTGGCTCTATATGTTCCTGTACTCGTGCGCCGGCTCCTGCGCCGCCGCGCCGGGG
CTGCTGCTCCTGGGCTCTGGGTCCCGCGCCGCACACGACCCGCCAGCCCTGGCCACAGCT
CCGGACGGGACGCCCCCCAGGCTGCCGTTCCGGGCGCCGCCAGCCACCCCACTGGCTTCA
GGCAAGGAGATGGCCGAGGGCGCTGCGAGCCCGGAGGAGCAGAGTCCCGAGGTGCCGGAC
TCCCCAAGCCCCATCTCCAGCTTTTTCAGTGGGTCTGGGAGCAAGCAGCTGCCGCAGGCC
ATCATCATCGGCGTGAAGAAGGGCGGCACGCGGGCGCTGCTGGAGTTTCTGCGCGTGCAC
CCCGACGTGCGCGCCGTGGGCGCCGAGCCCCATTTCTTCGATCGCAGCTACGACAAGGGC
CTCGCTTGGTACCGGGACCTGATGCCCAGAACCCTGGACGGGCAGATCACCATGGAGAAG
ACGCCCAGTTACTTCGTCACGCGGGAGGCCCCCGCGCGCATCTCGGCCATGTCCAAGGAC
ACCAAGCTCATCGTGGTGGTGCGGGACCCGGTGACCAGGGCCATCTCGGACTACACGCAG
ACGCTGTCCAAGCGGCCCGACATCCCCACCTTCGAGAGCTTGACGTTCAAAAACAGGACA
GCGGGCCTCATCGACACGTCGTGGAGCGCCATCCAGATCGGCATCTACGCCAAGCACCTG
GAGCACTGGCTGCGCCACTTCCCCATCCGCCAGATGCTCTTCGTGAGCGGCGAGCGGCTC
ATCAGCGACCCGGCCGGGGAGCTGGGCCGCGTGCAAGACTTCCTGGGCCTCAAGAGGATC
ATCACGGACAAGCACTTCTACTTCAACAAGACCAAGGGCTTCCCCTGCCTGAAGAAGGCG
GAGGGCAGCAGCCGGCCCCATTGCCTGGGCAAGACCAAGGGCAGGACCCATCCTGAGATC
GACCGCGAGGTGGTGCGCAGGCTGCGCGAGTTCTACCGGCCTTTCAACCTCAAGTTCTAC
CAGATGACCGGGCACGACTTTGGCTGGGATTGA

Clone variation with respect to NM_006041.1
>OriGene 5' read for NM_006041 unedited
ATTTTGTAATACGACTCACTATAGGGCGGCACGCGAATTCGCACGAGGGGAAGTGCCGGG
GCTGCTCGAGGCTCATTTCTTATGACTGCAAGGAGGCAGCCCCGGCGTGCGGCGGTGCGC
ACAGTCTATAGTGGCCAGGGCGCGAGAGTGCAACGTCCTCCTGGCCCCGAGCGCGTCGTC
GCGCCCCGGGAGCAGACCCTCGCCCAGCAGTTACCGCCGTCCCGACTTTCCGTTCCAGTT
GCAGCTCCTGCCGGGCAACATGTCAAGATCCGCCGCCGCTACAGCTGCCGCCGCCACCTG
GGGAAGATCAGCAGCAGCAGCGGCGGCCGCGGGCACACGGGGGCAATAAACCGATCCACC
CGGGCGTCCAGCGTGCCGGGGAACCCTCTCTGCGCTCACTGCCCGGCGGGACCCACGCCA
TGTGCTGAGCCATGTCCCTGGCCGCGCCCGCGGGCAGCGCATGGGGCAGCGCCTGAGTGG
CGGCAGATCTTGCCTCGATGTCCCCGGCCGGCTCCTACCGCAGCCGCCGCCGCCCCCGCC
GCCGGTGAGGATGAAGCTCGCGCTGCTCTTCGCCATGCTCTGCGTCTGGCTCTATATGTT
CCTGTACTCGTGCGCCGGCTCCTGCGCCGCCGCGCCGGGGCTGCTGCTCCTGAGCTCTGG
GTCCCGCGCCGNACACGACCCGNCAGCCCTGGCCACAGCTNCGGACGGGACGCCCNCCAT
GCTGNCGTTCCAGTCGCCGNCAGCCACCCCACTGGCTTCATGCATGGATATGGCCGATGG
CGCTGCGAGCCCCGATGATCATAGTCCCGATGTGCCGGACTCCCCATGCCCATCTNCAGC
TTTTTCATGGGGTCTGGGAGTCAGCAGCTGGCGCATGCCATCTCATTCGCGTGATTAATG
GCGNACGCGGNCGCTGCTGNAGTTTTTGCGCGGCACCCCGACTGCGCCCGTGGTCGCGAG
CCCATTTTTGGTTGCACTTCGATAGGCCTCCTTGGTCCGGNACTGATGCAAACCCGNACG
GCGATACCATGGAATACCC
Restriction Sites NotI-NotI     
ACCN NM_006041
ORF Size 1173 bp
Insert Size 3000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_006041.1, NP_006032.1
RefSeq Size 2032
RefSeq ORF 1173
Locus ID 9953
Domains Sulfotransfer
Protein Families Transmembrane
Protein Pathways Glycosaminoglycan degradation, Heparan sulfate biosynthesis
Gene Summary The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Transcript Variant: This variant (1) represents the longer transcript. It encodes the protein.

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