RRAGB (NM_006064) Human Untagged Clone

CAT#: SC116386

RRAGB (untagged)-Human Ras-related GTP binding B (RRAGB), transcript variant RAGBs

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RRAGB
• Synonyms: bA465E19.1; RAGB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116386 sequence for NM_006064 edited (data generated by NextGen Sequencing)
  ATGGAAGAATCTGACTCTGAGAAAACGACGGAGAAAGAAAATCTGGGGCCGAGAATGGAT
  CCACCACTAGGGGAACCGGAAGGATCGCTTGGGTGGGTGCTACCAAATACAGCCATGAAG
  AAAAAGGTGCTGTTGATGGGTAAAAGTGGGTCTGGTAAGACCAGCATGAGGTCTATTATC
  TTTGCAAATTATATTGCCAGAGACACACGTCGCCTTGGCGCAACAATTGATGTAGAACAT
  TCTCATGTTCGATTTCTGGGAAACCTGGTATTGAACCTGTGGGATTGTGGTGGGCAAGAC
  ACCTTCATGGAAAATTATTTCACTAGCCAACGGGACAACATCTTCCGAAATGTGGAGGTT
  CTGATTTATGTCTTTGATGTGGAGAGCCGCGAACTGGAAAAGGACATGCACTATTACCAA
  TCATGCCTGGAGGCCATTCTGCAGAATTCTCCAGATGCCAAAATATTTTGCTTGGTACAC
  AAAATGGATCTGGTACAGGAGGATCAACGGGACCTGATTTTTAAAGAGCGAGAAGAAGAT
  TTGAGGCGTTTGTCTCGCCCATTGGAATGTTCTTGTTTCCGAACATCTATCTGGGATGAA
  ACCCTCTATAAGGCTTGGTCCAGCATAGTTTATCAGCTGATTCCCAATGTTCAGCAGCTG
  GAAATGAACCTAAGGAATTTTGCTGAAATTATCGAAGCTGATGAAGTACTTCTTTTTGAG
  AGAGCTACTTTTCTGGTAATTTCTCACTATCAGTGTAAAGAGCAGCGTGATGCCCATAGA
  TTTGAGAAAATAAGCAACATTATTAAGCAGTTCAAGCTGAGCTGCAGCAAGCTGGCTGCC
  TCTTTCCAGAGTATGGAAGTCAGGAACTCTAACTTCGCTGCTTTCATTGACATCTTTACA
  TCCAACACTTATGTGATGGTTGTGATGTCTGATCCGTCCATTCCTTCTGCAGCTACTCTG
  ATCAACATCCGCAATGCCAGGAAACACTTTGAAAAGCTGGAAAGAGTGGATGGACCAAAG
  CAGTGTCTTCTCATGCGCTAA
  
  Clone variation with respect to NM_006064.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006064 unedited
  NGTCAAAATTTGTATACGACTCCTATAGGGCGGCCGCGAATCGGCACGAGGCTGGGTTCC
  TGAGGGCGGGTGGTTAGGTCGTAACTACTGCCCCCGCCGGCTGACTCTCCGAGCGGCCGG
  GCTCGGAAGCCACGAGCCAGCTGAGGCGTTCTCCGCTTAGTGCCTACGGCATGGGTCAGC
  TCTTTCTGCCACCTCCGCCTTCGCGGTCCTCACCTCTTTGCGGGTGAAGTTACCTTTGGG
  TTTCCAGACCTTGGGGGCCTGAGGCCCAAACTCGGGACGAACCCCTAACCCACCTCTCTT
  TTCCTGTCATTCTCCAACTCTTACTTTGTACCACGGAATCACTTGGCCTTAAAGCTAGCC
  AGCTCGGCCGTGCCTTGAGGCCAGGTTCGAGAGATAAAGGTAACCGTGGGGAAAGCGGCC
  CCCCAGTGGACAAAGGCGGAGGCAAGAATAGAGCAGGCCTGAGGGCCATAGGCGATGAGA
  ATAGGCAGTTGAGGGGTGAAAAAGAAAACAAACAAACAACAACAACAAACCCTGAAGAGT
  ACTGAAGATTTAGAAGGGACTGGAAAGGACTTGTTGCGCAATGGAAGAATCTGACTCTGA
  GAAAACGACGGAGAAAGAAAATCTGGGGCCGAGAATGGATCCACCACTAGGGGAACCGGA
  AGGATCGCTTGGGTGGGTGCTACCAAATACAGCCATGAAGAANAAGGTGCTGTTGATGGG
  TAAAAGTGGGGTCTGGTAAGACCAGCATGAGGTCTATTATCTTTGCAAATTATATTGCCA
  GAGACACACGTCGCCTTGGCGCAACATACTAGACCGTATACATAGTCTTCAATTAAATAG
  CAGTTGAGCACCTACTCTCTCGTAGACTCTGGTGGAAATACAAGACATTNGATGTAGACA
  TTCTCATGNTCGATTTCTGGAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006064
• ORF Size: 1041 bp
• Insert Size: 2240
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_006064.3, NP_006055.3
• RefSeq Size: 2133
• RefSeq ORF: 1041
• Locus ID: 10325
• Domains: Gtr1_RagA
• Gene Summary: Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2, also known as RAGBs) lacks an alternate in-frame exon in the coding region, compared to variant 1, resulting in a shorter isoform (2).