AKAP8 (NM_005858) Human Untagged Clone

CAT#: SC116499

AKAP8 (untagged)-Human A kinase (PRKA) anchor protein 8 (AKAP8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKAP8
• Synonyms: AKAP-8; AKAP-95; AKAP 95; AKAP95
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116499 sequence for NM_005858 edited (data generated by NextGen Sequencing)
  ATGGACCAGGGCTACGGAGGCTACGGGGCGTGGAGTGCTGGACCTGCCAACACCCAGGGT
  GCATATGGAACTGGTGTGGCCAGCTGGCAAGGTTATGAAAACTACAATTACTATGGCGCC
  CAGAACACCAGTGTCACCACAGGCGCAACCTACAGCTACGGCCCAGCCTCGTGGGAGGCC
  GCCAAGGCCAATGATGGCGGCCTGGCGGCCGGGGCCCCTGCCATGCACATGGCCTCTTAC
  GGCCCAGAGCCATGCACCGACAATTCCGACTCCCTCATTGCCAAGATCAACCAGCGTTTG
  GACATGATGTCCAAGGAAGGAGGCAGGGGCGGGAGCGGCGGCGGTGGGGAGGGCATACAG
  GACCGGGAGAGCTCCTTCCGCTTCCAGCCGTTCGAGTCCTATGACTCCAGGCCCTGCCTG
  CCGGAGCACAACCCCTACCGCCCCAGCTACAGCTACGACTATGAGTTCGACCTGGGGTCC
  GACCGCAATGGCAGCTTTGGGGGGCAGTACAGTGAATGCCGAGACCCAGCCCGGGAGCGG
  GGCTCCCTTGATGGCTTCATGCGGGGCCGGGGCCAGGGCCGCTTCCAGGACCGGAGCAAC
  CCTGGCACCTTCATGCGCAGCGACCCCTTCGTGCCCCCCGCTGCGTCCTCTGAGCCCCTG
  TCCACGCCCTGGAACGAGCTGAACTACGTGGGTGGACGGGGCCTGGGAGGGCCCTCCCCC
  AGCCGGCCACCTCCGTCCCTCTTCTCCCAGTCCATGGCTCCCGACTACGGCGTGATGGGC
  ATGCAGGGGGCGGGCGGCTATGACAGCACCATGCCCTACGGATGTGGCCGCTCGCAGCCT
  CGGATGCGGGATCGGGATCGGCCCAAGAGGAGAGGGTTTGACCGCTTCGGACCAGATGGC
  ACGGGCAGGAAACGGAAGCAGTTCCAACTTTACGAGGAGCCAGACACCAAACTGGCCCGG
  GTTGACAGTGAAGGAGATTTCTCCGAAAATGATGACGCAGCTGGTGACTTCCGCTCAGGA
  GATGAAGAATTCAAGGGTGAGGATGAACTCTGCGACTCTGGGAGGCAAAGAGGAGAGAAG
  GAGGACGAGGACGAGGATGTGAAGAAGAGAAGGGAAAAGCAAAGGAGAAGAGACAGGACG
  CGGGACCGTGCAGCCGACAGAATTCAGTTTGCCTGTTCTGTATGCAAGTTCCGTAGCTTT
  GATGACGAAGAGATCCAGAAGCATCTGCAAAGCAAATTTCACAAAGAGACCCTGCGGTTC
  ATAAGCACCAAGCTGCCCGACAAGACCGTGGAGTTCCTCCAGGAATACATTGTAAACAGA
  AATAAGAAAATTGAGAAGCGGCGTCAGGAATTGATGGAGAAAGAAACCGCAAAACCAAAA
  CCAGATCCTTTCAAAGGGATTGGCCAGGAGCACTTCTTCAAGAAGATCGAGGCTGCTCAC
  TGCCTGGCCTGCGACATGCTAATTCCTGCACAGCCGCAGCTCCTCCAGCGGCACCTGCAC
  TCCGTGGACCACAATCACAACCGCAGGTTGGCTGCTGAACAGTTCAAGAAAACCAGTCTC
  CATGTGGCTAAGAGTGTTTTGAACAACAGACATATAGTGAAGATGCTGGAAAAATACCTC
  AAGGGTGAGGACCCTTTCACCAGTGAAACTGTTGATCCAGAAATGGAAGGAGATGACAAT
  TTAGGAGGTGAGGATAAGAAAGAGACACCTGAGGAGGTGGCCGCGGACGTCTTAGCAGAG
  GTGATTACAGCAGCAGTGAGGGCCGTAGATGGGGAAGGAGCGCCCGCTCCAGAGAGCAGC
  GGGGAGCCGGCTGAGGACGAAGGCCCCACGGACACAGCGGAGGCCGGTAGTGATCCTCAA
  GCCGAACAGCTGCTGGAAGAGCAGGTGCCCTGTGGAACGGCACATGAGAAGGGCGTCCCC
  AAGGCCAGAAGTGAGGCTGCAGAGGCTGGAAATGGCGCCGAGACAATGGCAGCAGAGGCA
  GAAAGTGCCCAAACCAGAGTTGCTCCTGCCCCAGCTGCCGCGGATGCTGAAGTGGAACAA
  ACTGATGCAGAGTCTAAAGACGCTGTTCCCACAGAATGA
  
  Clone variation with respect to NM_005858.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005858 unedited
  GGGTGCACAATATTTGTATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGTGC
  GCTGAACGCATGCGTGCTGTGGTCGCCTAGTAAACGGGGCTGCTGGTGGGCCGCGTCGAA
  GACATGGACCAGGGCTACGGAGGCTACGGGGCGTGGAGTGCTGGACCTGCCAACACCCAG
  GGTGCATATGGAACTGGTGTGGCCAGCTGGCAAGGTTATGAAAACTACAATTACTATGGC
  GCCCAGAACACCAGTGTCACCACAGGCGCAACCTACAGCTACGGCCCAGCCTCGTGGGAG
  GCCGCCAAGGCCAATGATGGCGGCCTGGCGGCCGGGGCCCCTGCCATGCACATGGCCTCT
  TACGGCCCAGAGCCATGCACCGACAATTCCGACTCCCTCATTGCCAAGATCAACCAGCGT
  TTGGACATGATGTCCAAGGAAGGAGGCAGGGGCGGGAGCGGCGGCGGTGGGGAGGGCATA
  CAGGACCGGGAGAGCTCCTTCCGCTTCCAGCCGTTCGAGTCCTATGACTCCAGGCCCTGC
  CTGCCGGAGCACAACCCCTACCGCCCCAGCTACAGCTACGACTATGAGTTCGACCTGNGG
  TCCGACCGCAATGGCAGCTTTGGGGGGCAGTACAGTGAATGCCGAGACCCAGCCCGGGAG
  CGGNGCTCCCTTGATGGCTTCATGCGGNGCCGGGGCCAGGGCCGCTTCCCAGACCGGAGC
  AACCCTGGCACCTTCATGCGCAGCGACCCCCTTCGTGCCCCCCGCTGCGTCCTCTGAGCC
  CCTGTNCACGCCCTGNAACGAGCTGAACTACCGTGGGTGGACGGNGCCCTGGGAGGGCCC
  CCCTCCCCGGCCGGCCACCNTCCGTCCCNTCTTCTCCCAGTCCATTGGCTCCCGACTACN
  GCGTGATGGGCATGCAGGGGGGCGGCCNCTATGACAGCACATGCCCTACGATGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005858 unedited
  CTATGAACCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAAAAGG
  GGTCTTGCTATGTTGTCCAGGTTGGTCTTGAACTCCTGGGCTTAAGCTATCCTCTCACCA
  CGGCCTCCCCAAGTGCTGGGATTATAGGTATGCATCACCGTGCCTGGCCAAATTCTCTTT
  GTAAATACATTTGAGTGGTAGTAACTAATTTTAAAGGAAAAAAACCTGAAGTAATCTAGA
  GGTGGAACACAAATGAGGTAAAATATTAGAGAACTGATTCAGCAAGGACTAAAGATTGGG
  ACGCAATGCCCTCTGCACAGTCTGGTTCTTGAGGTTGCGGTGGGTGTGTTTCCAGTGGCG
  TAGGTCGGTCAGATACTTCTGGCCTTTGGGAGTGCGTGGATGTGACGCGGTCAGTGCCAC
  ATGTGAACCAGGTGCTGCGAAGTCCTGTGAAAGTCACACACCATATGGTGCACTACAAAG
  GTATAGGTTAAAGGCTGAAGCTTGAAACATACAAAAAAAAATCCTCTATAGAGCAAGATA
  TATTCCTAGTATTCAGCTGTTCCCAACCAAATAAAAAAAAAAAATTAAGGAAAAAAATAA
  AAAAGGAAGCATTCCATCAGTGGCTGTATTGAACAAGTAATGTATCATCAAGATATAATC
  ACCCAACCTTTATTATTCCAAGTGCACTACTGTCAAGAGACATGTTACAGCCGCTAGGGA
  CAATGTACTCAAGCTTTGAAACCTGGGCAAGAAACCCACGACTGCATGAACAAGCCGTGA
  GAGCACTGTTCAGGAGGAAACCTGGCCTCTTCCCCAAATAGATTCAGCTTATTTGGAGCA
  CCCCCTTGACTGGTTACAACCACGGAAAAGCACACCCCTTCTTATTCCAAAGCCTTCTGG
  GACAGGGATATACAATATTTGTGCCACCCGCTTTCACACCGGCACATTTGTCGCTTAACC
  TGCGGGCATTGGGCCGAACACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005858
• ORF Size: 2079 bp
• Insert Size: 3160
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_005858.2, NP_005849.1
• RefSeq Size: 3545
• RefSeq ORF: 2079
• Locus ID: 10270
• Domains: AKAP95
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]