TBL1 (TBL1X) (NM_005647) Human Untagged Clone

CAT#: SC116610

TBL1X (untagged)-Human transducin (beta)-like 1X-linked (TBL1X), transcript variant 1


  "NM_005647" in other vectors (6)

Reconstitution Protocol

USD 980.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TBL1X
Synonyms EBI; SMAP55; TBL1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC116610 sequence for NM_005647 edited (data generated by NextGen Sequencing)
ATGACCGAGCTCGCTGGCGCCTCTTCATCGTGCTGCCACCGCCCTGCAGGAAGAGGGGCC
ATGCAGTCAGTCTTGCACCACTTTCAACGTTTGCGAGGGAGAGAGGGTGGTTCCCACTTC
ATCAACACCTCATCGCCGCGAGGTGAGGCTAAGATGAGCATAACCAGTGACGAGGTGAAC
TTTCTGGTGTATCGGTATCTCCAGGAGTCAGGTTTTTCCCACTCGGCTTTCACGTTTGGG
ATTGAGAGCCACATCAGCCAGTCCAACATCAATGGGACGCTAGTGCCACCGGCCGCCCTC
ATCTCCATTCTCCAGAAGGGCCTGCAGTATGTAGAGGCCGAGATCAGTATCAACGAGGAT
GGCACAGTGTTCGACGGCCGCCCCATAGAGTCCCTGTCACTGATAGACGCCGTGATGCCC
GACGTGGTGCAGACGCGGCAGCAGGCATTCCGAGAGAAGCTCGCTCAGCAGCAAGCCAGT
GCGGCGGCGGCGGCGGCTGCGGCCACGGCAGCAGCGACAGCAGCCACCACGACCTCAGCC
GGCGTTTCCCACCAAAATCCATCGAAGAACAGAGAGGCCACGGTGAATGGGGAAGAGAAC
AGAGCACATTCAGTCAATAATCACGCGAAGCCAATGGAAATAGATGGAGAGGTTGAGATT
CCATCCAGCAAAGCCACAGTCCTTCGGGGCCATGAGTCTGAGGTGTTCATTTGTGCCTGG
AATCCTGTCAGTGATTTGCTAGCCTCCGGATCTGGAGACTCAACTGCAAGGATATGGAAC
CTGAATGAGAATAGCAACGGGGGCTCCACCCAGCTCGTGTTGAGGCACTGTATACGAGAG
GGGGGCCATGACGTCCCGAGTAACAAAGACGTCACCTCACTGGACTGGAATACCAATGGA
ACACTCTTGGCTACGGGTTCATATGACGGTTTTGCAAGAATATGGACGGAAGATGGTAAC
CTGGCCAGCACCTTAGGCCAACATAAAGGCCCCATCTTTGCCTTGAAATGGAACCGAAAG
GGGAATTACATTTTGAGTGCTGGTGTAGACAAAACAACAATAATTTGGGATGCCCACACA
GGAGAAGCCAAACAGCAGTTTCCTTTTCATTCAGCCCCTGCCCTTGATGTGGACTGGCAG
AACAACACGACCTTTGCCTCCTGTAGCACAGACATGTGTATCCATGTGTGCAGGCTCGGC
TGTGACCGCCCAGTCAAAACCTTCCAGGGACACACAAACGAGGTCAACGCCATCAAATGG
GATCCGTCTGGAATGTTGCTGGCATCCTGCTCGGATGACATGACATTGAAGATCTGGAGC
ATGAAACAGGAGGTGTGCATCCATGATCTTCAGGCTCACAATAAAGAGATCTACACCATC
AAGTGGAGCCCCACTGGGCCCGCCACCAGCAACCCAAACTCCAACATCATGTTGGCAAGT
GCTTCGTTTGATTCTACGGTGCGACTGTGGGACATAGAACGAGGCGTCTGCACCCACACG
CTCACGAAGCATCAGGAGCCTGTCTATAGCGTAGCTTTCAGCCCTGATGGGAAGTACTTG
GCCAGTGGATCCTTCGACAAGTGCGTCCATATCTGGAATACTCAGAGTGGAAATCTTGTC
CACAGCTACCGAGGCACTGGCGGCATCTTCGAGGTGTGCTGGAACGCCCGAGGAGACAAA
GTGGGTGCCAGCGCGTCCGACGGCTCTGTGTGTGTTTTGGATCTGCGGAAGTAA

Clone variation with respect to NM_005647.3
>OriGene 5' read for NM_005647 unedited
CGAATTCGGCACCAGAAGGAGCCCTGGCCTCCTTGCAGAAACATCGAGGTGACATGTAGC
ATGACCGAGCTCGCTGGCGCCTCTTCATCGTGCTGCCACCGCCCTGCAGGAAGAGGGGCC
ATGCAGTCAGTCTTGCACCACTTTCAACGTTTGCGAGGGAGAGAGGGTGGTTCCCACTTC
ATCAACACCTCANNCTTCTTGAGGTGAGGCTAAGATGAGCATAACCAGTGACGAGGTGAA
CTTTCTGGTGTATCGGTATCTCCAGGAGTCAGGTTTTTCCCACTCGGCTTTCACGTTTGG
GATTGAGAGCCACATCAGCCAGTCCAACATCAATGGGACGCTAGTGCCACCGGCCGCCCT
CATCTCCATTCTCCAGAAGGGCCTGCAGTATGTAGAGGCCCGGATCAGTATCAACGAGGA
TGGCACAGTGTTCGACGGCCGCCCCATAGAGTCCCTGTCACTGATAGACGCCGTGATGCC
CGACGTGGTGCAGACGCCGCAGCAGGCATTCCGAGAGGAACTCGCTCAGCAGCAAGCCAA
TGCCGCGGCGGCGGCGGCTGCGGCCCCCGGAGCAGCGACACCACCCCCACGACCTCAGCC
CGCGTTTCCCCCCAAATCCTCCTAAACAAAAAGGCCCGGTGAAGGGGGAGAAACCCAGCC
CCTCAGTCATAATCCCCCAACCATGGGAAAGGAGGGGAGGGGAGATCCTTCAACAAAGCC
CAGCCCTCGGGCCCTGAGTCTGAGGGTCATTTG
>OriGene 3' read for NM_005647 unedited
ATACCTCTGNNACCGCGGCCGCTTTTCTANATTTTTTTAAAGGCGGCACAAAGGTTAAAA
AACATATAAGCAACAAGAACAAAGCAGACCCTTACATTTGACAAAGTGCACTTCACTTGG
CTCCATGATCTATTTCTTAGAAAGACTAAACAAAAGTCAAGTCCTACGGTGTCGCGAGGG
GTCAGAGGGTTTCACCCTGTAACGTCCGGCCCTTTTGGTTTTTTTTGGGGCAGCATCCCT
TTCCCAGGTGTGTGCTGGACCTTATAATTTGTCACTGTGAACCCGACCAAACACTCTAGG
AAGGTCTGTCATGCTATGTCTGCTTTCAAGGTCACGTTTGGTCACTAAGACTTAGGCATT
CCTCACCATGTTTTAAGAGCTGTAAACAACGTTGAACAATAACATTCCACAGGCCATTTC
TTGATTACAGGGATGACTCTACCAACATGCCCAGCACCCTAGAGGGTGAGCAGCGGTGTC
GCCCATGCTGGACGCTCTGAACACGGCTGCCCATGGTGTTGTCCCGCTGCCAACGGGGAT
GGATATGAACGGTGCTACCCGCATCTCCCGCTCGGCCCTGCTTGCCGCCGTCGGCTGCTG
AAGCCACGGACGGAGCCTGCGGCCCCAGGACTCCCATTACACTTCCCTCACCCTACCACT
TCCCCATGGCCTCCCCCTATTCCCGCACTTCTGCTCTCCCTCCGCAGACCCCTTCGCCTC
CTGTCACTCTTCCCCCCCACTTTCACCGCAATCCTTCGCACTCATCCCACCGTCCCCCTT
CCCCGCTTCATCCCTTTTTCCCGTCTCCTCCCCCCTCTCCCTGGCTTATTTTTGTCACTC
CCCCCCCATTCCCCCGTTCCTCCTCCCCGGTTGCGCCGCGCATCCGCCCCTCTCCCCCCT
CCTGACCCAATTTTCCCGTCCCTCTCCCGCCCCCCTACTTTTTCCCCCCCCCCTTC
Restriction Sites NotI-NotI     
ACCN NM_005647
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005647.2, NP_005638.1
RefSeq Size 5886 bp
RefSeq ORF 1734 bp
Locus ID 6907
Cytogenetics Xp22.31-p22.2
Domains WD40, LisH
Protein Families Transcription Factors
Protein Pathways Wnt signaling pathway
Gene Summary 'The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq, Nov 2008]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

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