TBL1 (TBL1X) (NM_005647) Human Untagged Clone

CAT#: SC116610

TBL1X (untagged)-Human transducin (beta)-like 1X-linked (TBL1X), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TBL1X
• Synonyms: EBI; SMAP55; TBL1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116610 sequence for NM_005647 edited (data generated by NextGen Sequencing)
  ATGACCGAGCTCGCTGGCGCCTCTTCATCGTGCTGCCACCGCCCTGCAGGAAGAGGGGCC
  ATGCAGTCAGTCTTGCACCACTTTCAACGTTTGCGAGGGAGAGAGGGTGGTTCCCACTTC
  ATCAACACCTCATCGCCGCGAGGTGAGGCTAAGATGAGCATAACCAGTGACGAGGTGAAC
  TTTCTGGTGTATCGGTATCTCCAGGAGTCAGGTTTTTCCCACTCGGCTTTCACGTTTGGG
  ATTGAGAGCCACATCAGCCAGTCCAACATCAATGGGACGCTAGTGCCACCGGCCGCCCTC
  ATCTCCATTCTCCAGAAGGGCCTGCAGTATGTAGAGGCCGAGATCAGTATCAACGAGGAT
  GGCACAGTGTTCGACGGCCGCCCCATAGAGTCCCTGTCACTGATAGACGCCGTGATGCCC
  GACGTGGTGCAGACGCGGCAGCAGGCATTCCGAGAGAAGCTCGCTCAGCAGCAAGCCAGT
  GCGGCGGCGGCGGCGGCTGCGGCCACGGCAGCAGCGACAGCAGCCACCACGACCTCAGCC
  GGCGTTTCCCACCAAAATCCATCGAAGAACAGAGAGGCCACGGTGAATGGGGAAGAGAAC
  AGAGCACATTCAGTCAATAATCACGCGAAGCCAATGGAAATAGATGGAGAGGTTGAGATT
  CCATCCAGCAAAGCCACAGTCCTTCGGGGCCATGAGTCTGAGGTGTTCATTTGTGCCTGG
  AATCCTGTCAGTGATTTGCTAGCCTCCGGATCTGGAGACTCAACTGCAAGGATATGGAAC
  CTGAATGAGAATAGCAACGGGGGCTCCACCCAGCTCGTGTTGAGGCACTGTATACGAGAG
  GGGGGCCATGACGTCCCGAGTAACAAAGACGTCACCTCACTGGACTGGAATACCAATGGA
  ACACTCTTGGCTACGGGTTCATATGACGGTTTTGCAAGAATATGGACGGAAGATGGTAAC
  CTGGCCAGCACCTTAGGCCAACATAAAGGCCCCATCTTTGCCTTGAAATGGAACCGAAAG
  GGGAATTACATTTTGAGTGCTGGTGTAGACAAAACAACAATAATTTGGGATGCCCACACA
  GGAGAAGCCAAACAGCAGTTTCCTTTTCATTCAGCCCCTGCCCTTGATGTGGACTGGCAG
  AACAACACGACCTTTGCCTCCTGTAGCACAGACATGTGTATCCATGTGTGCAGGCTCGGC
  TGTGACCGCCCAGTCAAAACCTTCCAGGGACACACAAACGAGGTCAACGCCATCAAATGG
  GATCCGTCTGGAATGTTGCTGGCATCCTGCTCGGATGACATGACATTGAAGATCTGGAGC
  ATGAAACAGGAGGTGTGCATCCATGATCTTCAGGCTCACAATAAAGAGATCTACACCATC
  AAGTGGAGCCCCACTGGGCCCGCCACCAGCAACCCAAACTCCAACATCATGTTGGCAAGT
  GCTTCGTTTGATTCTACGGTGCGACTGTGGGACATAGAACGAGGCGTCTGCACCCACACG
  CTCACGAAGCATCAGGAGCCTGTCTATAGCGTAGCTTTCAGCCCTGATGGGAAGTACTTG
  GCCAGTGGATCCTTCGACAAGTGCGTCCATATCTGGAATACTCAGAGTGGAAATCTTGTC
  CACAGCTACCGAGGCACTGGCGGCATCTTCGAGGTGTGCTGGAACGCCCGAGGAGACAAA
  GTGGGTGCCAGCGCGTCCGACGGCTCTGTGTGTGTTTTGGATCTGCGGAAGTAA
  
  Clone variation with respect to NM_005647.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005647 unedited
  CGAATTCGGCACCAGAAGGAGCCCTGGCCTCCTTGCAGAAACATCGAGGTGACATGTAGC
  ATGACCGAGCTCGCTGGCGCCTCTTCATCGTGCTGCCACCGCCCTGCAGGAAGAGGGGCC
  ATGCAGTCAGTCTTGCACCACTTTCAACGTTTGCGAGGGAGAGAGGGTGGTTCCCACTTC
  ATCAACACCTCANNCTTCTTGAGGTGAGGCTAAGATGAGCATAACCAGTGACGAGGTGAA
  CTTTCTGGTGTATCGGTATCTCCAGGAGTCAGGTTTTTCCCACTCGGCTTTCACGTTTGG
  GATTGAGAGCCACATCAGCCAGTCCAACATCAATGGGACGCTAGTGCCACCGGCCGCCCT
  CATCTCCATTCTCCAGAAGGGCCTGCAGTATGTAGAGGCCCGGATCAGTATCAACGAGGA
  TGGCACAGTGTTCGACGGCCGCCCCATAGAGTCCCTGTCACTGATAGACGCCGTGATGCC
  CGACGTGGTGCAGACGCCGCAGCAGGCATTCCGAGAGGAACTCGCTCAGCAGCAAGCCAA
  TGCCGCGGCGGCGGCGGCTGCGGCCCCCGGAGCAGCGACACCACCCCCACGACCTCAGCC
  CGCGTTTCCCCCCAAATCCTCCTAAACAAAAAGGCCCGGTGAAGGGGGAGAAACCCAGCC
  CCTCAGTCATAATCCCCCAACCATGGGAAAGGAGGGGAGGGGAGATCCTTCAACAAAGCC
  CAGCCCTCGGGCCCTGAGTCTGAGGGTCATTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005647 unedited
  ATACCTCTGNNACCGCGGCCGCTTTTCTANATTTTTTTAAAGGCGGCACAAAGGTTAAAA
  AACATATAAGCAACAAGAACAAAGCAGACCCTTACATTTGACAAAGTGCACTTCACTTGG
  CTCCATGATCTATTTCTTAGAAAGACTAAACAAAAGTCAAGTCCTACGGTGTCGCGAGGG
  GTCAGAGGGTTTCACCCTGTAACGTCCGGCCCTTTTGGTTTTTTTTGGGGCAGCATCCCT
  TTCCCAGGTGTGTGCTGGACCTTATAATTTGTCACTGTGAACCCGACCAAACACTCTAGG
  AAGGTCTGTCATGCTATGTCTGCTTTCAAGGTCACGTTTGGTCACTAAGACTTAGGCATT
  CCTCACCATGTTTTAAGAGCTGTAAACAACGTTGAACAATAACATTCCACAGGCCATTTC
  TTGATTACAGGGATGACTCTACCAACATGCCCAGCACCCTAGAGGGTGAGCAGCGGTGTC
  GCCCATGCTGGACGCTCTGAACACGGCTGCCCATGGTGTTGTCCCGCTGCCAACGGGGAT
  GGATATGAACGGTGCTACCCGCATCTCCCGCTCGGCCCTGCTTGCCGCCGTCGGCTGCTG
  AAGCCACGGACGGAGCCTGCGGCCCCAGGACTCCCATTACACTTCCCTCACCCTACCACT
  TCCCCATGGCCTCCCCCTATTCCCGCACTTCTGCTCTCCCTCCGCAGACCCCTTCGCCTC
  CTGTCACTCTTCCCCCCCACTTTCACCGCAATCCTTCGCACTCATCCCACCGTCCCCCTT
  CCCCGCTTCATCCCTTTTTCCCGTCTCCTCCCCCCTCTCCCTGGCTTATTTTTGTCACTC
  CCCCCCCATTCCCCCGTTCCTCCTCCCCGGTTGCGCCGCGCATCCGCCCCTCTCCCCCCT
  CCTGACCCAATTTTCCCGTCCCTCTCCCGCCCCCCTACTTTTTCCCCCCCCCCTTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005647
• Insert Size: 4700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005647.2, NP_005638.1
• RefSeq Size: 5886 bp
• RefSeq ORF: 1734 bp
• Locus ID: 6907
• Cytogenetics: Xp22.31-p22.2
• Domains: WD40, LisH
• Protein Families: Transcription Factors
• Protein Pathways: Wnt signaling pathway
• Gene Summary: 'The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq, Nov 2008]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.