NUP153 (NM_005124) Human Untagged Clone

CAT#: SC116943

NUP153 (untagged)-Human nucleoporin 153kDa (NUP153)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NUP153
• Synonyms: HNUP153; N153
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005124 edited
  GGCCTCCGCCTCTGCCTCTCCCGCCCCCTTACCCGCCCCGGAGCGGGAAGCGGCGGAGGC
  TCCGCCATGGCCTCGGGAGCCGGAGGAGTCGGAGGGGGCGGTGGCGGCAAGATCCGGACG
  CGGCGTTGCCACCAGGGGCCAATTAAGCCTTACCAGCAGGGGCGACAACAGCATCAGGGC
  ATTCTTAGCAGGGTTACAGAATCTGTTAAGAATATTGTGCCAGGGTGGCTACAAAGATAC
  TTCAACAAGAATGAAGATGTATGCAGCTGTTCAACAGACACAAGCGAGGTTCCACGCTGG
  CCAGAAAATAAAGAGGACCATCTGGTATATGCCAATGAGGAGAGCTCTAATATTACTGAT
  GGGAGAATCACACCTGAGCCAGCAGTCAGTAATACAGAAGAACCTTCAACAACTAGTACT
  GCTTCAAATTATCCAGATGTGTTAACAAGGCCTTCTCTTCATCGGAGCCATCTGAATTTT
  TCCATGTTGGAATCCCCTGCATTACACTGTCAGCCATCTACATCCTCGGCATTCCCAATT
  GGCAGTTCGGGATTTTCCCTTGTAAAGGAAATTAAAGATTCTACCTCTCAGCATGATGAT
  GATAACATCTCAACTACCAGTGGTTTTTCTTCAAGAGCTTCTGATAAAGATATAACTGTT
  TCAAAGAACACTTCATTGCCACCTCTGTGGTCCCCAGAAGCTGAACGTTCTCACTCACTC
  TCACAGCACACTGCCACCAGCTCAAAAAAACCAGCATTCAACTTGTCTGCCTTTGGAACA
  CTTTCCCCTTCACTTGGGAATTCTTCAATCCTTAAAACCAGTCAGCTTGGAGATTCTCCT
  TTTTATCCTGGAAAAACAACATACGGTGGGGCAGCAGCTGCTGTAAGACAGTCTAAACTA
  CGAAATACACCTTATCAGGCACCAGTTAGAAGACAAATGAAAGCTAAGCAACTCAGTGCA
  CAATCTTACGGTGTGACCAGTTCAACAGCTCGGCGAATATTGCAGTCTTTAGAGAAGATG
  TCAAGCCCTTTAGCGGATGCAAAAAGAATTCCATCCATTGTTTCTTCTCCTCTGAATTCT
  CCTCTTGATAGGAGTGGGATAGATATCACAGATTTTCAGGCCAAAAGAGAAAAGGTGGAT
  TCTCAATATCCTCCTGTTCAGAGACTTATGACCCCAAAGCCAGTTTCCATAGCAACAAAT
  CGAAGTTTTTATTTTAAACCATCTCTGACTCCTTCTGGTGAATTCAGGAAGACTAATCAA
  AGAATAGATAACAAGTGCAGTACTGGATATGAAAAAAATATGACACCCGGACAAAATAGA
  GAACAACGAGAAAGTGGCTTTTCATATCCAAATTTCAGTTTGCCTGCAGCCAATGGTTTA
  TCTTCTGGAGTAGGTGGTGGAGGTGGCAAGATGAGACGAGAAAGAACACGCTTTGTTGCT
  TCTAAACCTCTGGAGGAGGAGGAAATGGAAGTTCCAGTATTACCGAAAATCTCTCTACCG
  ATCACCAGTTCTTCACTGCCTACCTTTAATTTTAGTTCCCCTGAGATCACAACTTCCTCT
  CCATCACCCATCAATTCGTCTCAAGCATTAACAAACAAGGTACAAATGACCTCTCCGAGC
  AGCACTGGCAGTCCCATGTTTAAATTTTCATCTCCAATCGTAAAATCTACTGAGGCAAAT
  GTACTACCTCCATCATCTATTGGATTTACATTTAGTGTGCCTGTTGCAAAAACAGCAGAA
  CTTTCTGGTTCTAGTAGTACTTTAGAACCAATTATAAGTAGTTCAGCTCATCATGTCACT
  ACAGTGAACAGTACAAATTGTAAGAAGACACCACCTGAAGATTGTGAGGGTCCTTTTAGA
  CCTGCAGAAATCCTGAAAGAAGGAAGTGTTCTAGATATTCTGAAAAGCCCTGGTTTCGCA
  TCGCCGAAGATAGATTCTGTTGCTGCTCAGCCCACCGCAACAAGCCCAGTAGTTTATACA
  AGACCAGCAATAAGTAGCTTTTCTTCTAGTGGAATTGGGTTTGGGGAGAGTTTAAAAGCT
  GGGTCATCATGGCAGTGTGATACATGTCTACTCCAGAACAAAGTTACAGACAACAAATGC
  ATAGCCTGTCAAGCAGCAAAATTGTCACCCAGAGATACTGCTAAACAGACTGGAATTGAA
  ACACCAAATAAAAGTGGCAAAACAACTCTTTCTGCATCAGGGACAGGCTTTGGAGACAAA
  TTTAAACCAGTGATAGGCACTTGGGATTGTGATACCTGTTTAGTGCAAAATAAACCTGAA
  GCAATAAAATGTGTAGCCTGTGAAACACCGAAACCTGGAACTTGTGTGAAGCGAGCCCTT
  ACATTGACAGTGGTTTCGGAAAGTGCTGAGACTATGACTGCTTCATCTTCCAGCTGCACT
  GTAACCACTGGTACCTTAGGATTTGGAGATAAATTCAAAAGGCCCATTGGATCTTGGGAG
  TGTTCAGTATGCTGTGTTTCTAATAATGCAGAAGACAATAAGTGTGTGTCCTGTATGTCT
  GAGAAACCAGGAAGTTCAGTACCTGCTTCAAGTAGCAGCACTGTACCTGTCTCTCTGCCT
  TCTGGAGGCTCTCTAGGATTGGAAAAGTTCAAGAAACCCGAGGGAAGCTGGGACTGTGAA
  TTGTGCCTAGTGCAGAATAAGGCAGACTCTACCAAATGTTTGGCATGTGAAAGTGCAAAG
  CCAGGCACAAAATCTGGGTTTAAAGGCTTTGACACATCTTCCTCATCTTCGAACTCAGCA
  GCCTCCTCATCCTTCAAATTTGGTGTCTCATCATCCTCTTCTGGGCCTTCTCAGACTTTA
  ACAAGCACTGGAAATTTTAAATTTGGAGATCAGGGAGGATTCAAAATAGGTGTGTCATCT
  GATTCTGGGTCTATAAACCCCATGAGTGAAGGCTTTAAATTTTCTAAACCAATAGGAGAT
  TTTAAATTTGGAGTTTCATCTGAATCTAAGCCCGAAGAAGTTAAAAAAGATAGTAAGAAT
  GATAATTTTAAGTTTGGACTTTCTTCTGGTTTAAGCAACCCAGTTTCTTTAACTCCATTT
  CAATTTGGGGTATCTAATCTTGGACAGGAAGAAAAGAAAGAGGAACTGCCCAAATCTTCC
  TCTGCAGGTTTTAGCTTTGGTACAGGTGTTATTAACTCCACCCCTGCTCCTGCTAACACC
  ATAGTGACCTCTGAGAACAAGAGCAGCTTCAACCTTGGAACCATAGAAACCAAGAGTGCT
  TCAGTGGCTCCTTTCACATGTAAGACATCAGAAGCTAAAAAAGAAGAAATGCCTGCCACC
  AAAGGAGGATTCTCTTTTGGCAACGTGGAGCCTGCCTCTCTGCCATCTGCCTCAGTGTTT
  GTTTTGGGAAGGACAGAAGAGAAACAGCAAGAGCCTGTCACTTCTACTTCCCTAGTTTTT
  GGGAAGAAAGCTGACAATGAAGAGCCAAAGTGTCAACCAGTGTTTTCCTTTGGGAATTCA
  GAGCAAACCAAAGATGAGAATTCTTCAAAGTCCACATTTAGTTTTAGTATGACAAAACCA
  TCTGAGAAGGAATCTGAACAGCCAGCAAAAGCCACTTTTGCCTTTGGAGCTCAAACTAGT
  ACTACAGCTGATCAAGGTGCAGCAAAGCCAGTTTTTAGTTTCTTGAACAACAGTTCCTCT
  AGTTCAAGTACACCAGCCACTTCTGCTGGTGGTGGCATATTTGGTAGTTCCACCTCTTCC
  TCCAATCCACCTGTGGCTACCTTTGTGTTTGGACAGTCCAGCAATCCTGTGAGCAGCTCT
  GCCTTTGGTAACACTGCTGAATCCAGCACCTCTCAGTCTTTGCTATTTTCTCAAGATAGC
  AAACTAGCAACCACATCCAGCACAGGTACAGCTGTCACCCCATTTGTCTTTGGTCCAGGA
  GCCAGCAGTAATAATACTACCACCTCTGGTTTCGGCTTTGGAGCCACAACCACATCTAGC
  TCTGCAGGATCCTCCTTTGTATTTGGAACTGGACCCTCAGCACCATCTGCCAGTCCAGCA
  TTTGGTGCTAACCAGACCCCAACATTTGGACAAAGTCAAGGTGCCAGCCAGCCCAATCCC
  CCAGGCTTTGGATCTATATCATCTTCCACAGCATTATTTCCCACTGGTTCTCAGCCTGCA
  CCACCTACTTTTGGGACAGTGTCAAGCAGTAGCCAGCCCCCTGTGTTTGGACAGCAACCT
  AGTCAGTCTGCATTTGGCTCTGGAACAACTCCTAATTCTAGTTCGGCTTTCCAGTTTGGC
  AGCAGCACTACAAATTTCAACTTCACAAACAACAGTCCATCAGGAGTGTTCACATTTGGT
  GCAAATTCTAGCACACCTGCAGCCTCAGCCCAGCCTTCAGGCTCGGGGGGCTTTCCATTT
  AACCAGTCTCCAGCAGCATTTACAGTGGGGTCAAATGGGAAAAATGTGTTCTCTTCTTCT
  GGAACTTCATTCTCTGGTCGCAAGATAAAGACTGCTGTTAGACGCAGGAAATAAAGGTCA
  CATTGGTGTTGTACTCAATTTTAACAACAGCTGGTGCCCTGCTTTCAGATACTGGATTGT
  ACTTTGTGCTGGGGTTATCTGAAGTCAGATCTGCCTAAGGACTTCTTTAATTTTGGAATT
  TTCCTCCTTTCTCTTTCGTTACAGAAGCCCCACCCTGCCTCACCCACCCTTTTTTAAATA
  AATAAATAGCTAGACTGGTGACTGATTCTTCAGCAAAAATATTTTATGATCCAGCAGATT
  ATTCACTGATTTGACATAGTCTGGCTGTACCCAGGAATGGAGCCTGCACGGTGAATGGCT
  TTGTATAGAACCTCTTTGTCTACACCATTATGTGCGCTGATAAGCGTTCATGGAACGCGT
  TGAAATTGTAATTATATCTGAGGAATTCTGTATAGATTAGAATTCTGTATAGATTAGAGA
  GTGTTGAAACGGATGATTTCTATGCTGAGTTTGTGCTGGTGTATGTGTGAAGTGAGTGAG
  TTGGGTGTATTGTGCGCTAAACTTTTCTGATAGAGGAAGCCTGATTAAAGAATGGTCCGT
  GCTAAGGACTTGTTAGATCTAGTTCACTCTCCATTTAATAATTATATGCTATTTCTATAT
  TTTCATTCTCCTATCACCTGTCTTGCCTTTTTCATTATTTTATTATGAAACTTGTGTAAA
  TACAATTTTGTTTCTGTACTTTTTGGCATAACATAAATCTGTGAACTTGAAATTTGAATT
  TTGTGTTAGAGATTTTTTTGTTGTTTGTTTAGTCTTGTCTCAGATTTTATTATGTAAATC
  CCATTATTCAAAGTTGCCTAAATCCATTTGGAAATCTTT:AAAAAAAAATTGGGGATTCT
  TAAAGTTGAATTTATTGGCTTTTCTGATCCAGTTTTGTTTGGACCAAAAACCAGTATTGT
  ACAAAGTATTAAGCATATATTTTTATATTTACTAAAATGGACTGTGGTGACTTTGGATAA
  TAAGGAAAAGTTTAATATTAAAGCCATGTTTATTACAGTATAATTAACATGTTAAACCAT
  GGGATAAATGCCATCAATAAAAAATTATGACATAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_005124
• ORF Size: 4428 bp
• Insert Size: 5600
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005124.2, NP_005115.2
• RefSeq Size: 5687
• RefSeq ORF: 4428
• Locus ID: 9972
• Domains: zf-RanBP
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Gene Summary: Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.