Leupaxin (LPXN) (NM_004811) Human Untagged Clone

CAT#: SC117119

LPXN (untagged)-Human leupaxin (LPXN), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LPXN
• Synonyms: LDPL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004811, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGAGTTAGATGCCTTATTGGAGGAACTGGAACGCTCCACCCTTCAGGACAGTGATGAATATTCCA
  ACCCAGCTCCTCTTCCCCTGGATCAGCATTCCAGAAAGGAGACTAACCTTGATGAGACTTCGGAGATCCT
  TTCTATTCAGGATAACACAAGTCCCTTGCCGGCGCAGCTCGTGTATACTACCAATATCCAGGAGCTCAAT
  GTCTACAGTGAAGCCCAAGAGCCAAAGGAATCACCACCACCTTCTAAAACGTCAGCAGCTGCTCAGTTGG
  ATGAGCTCATGGCTCACCTGACTGAGATGCAGGCCAAGGTTGCAGTGAGAGCAGATGCTGGCAAGAAGCA
  CTTACCAGACAAGCAGGATCACAAGGCCTCCCTGGACTCAATGCTTGGGGGTCTGGAGCAGGAATTGCAG
  GACCTTGGCATTGCCACAGTGCCCAAGGGCCATTGTGCATCCTGCCAGAAACCGATTGCTGGGAAGGTGA
  TCCATGCTCTAGGGCAATCATGGCATCCTGAGCATTTTGTCTGTACTCATTGCAAAGAAGAGATTGGCTC
  CAGTCCCTTCTTTGAGCGGAGTGGCTTGGCCTACTGCCCCAACGACTACCACCAACTTTTTTCTCCACGC
  TGTGCTTACTGCGCTGCTCCCATCCTGGATAAAGTGCTGACAGCAATGAACCAGACCTGGCACCCAGAGC
  ACTTCTTCTGCTCTCACTGCGGAGAGGTGTTTGGTGCAGAAGGCTTTCATGAGAAGGACAAGAAGCCATA
  TTGCCGAAAGGATTTCTTAGCCATGTTCTCACCCAAGTGTGGTGGCTGCAATCGCCCAGTGTTGGAAAAC
  TACCTTTCAGCCATGGACACTGTCTGGCACCCAGAGTGCTTTGTTTGTGGGGACTGCTTCACCAGTTTTT
  CTACTGGCTCCTTCTTTGAACTGGATGGACGTCCATTCTGTGAGCTCCATTACCATCACCGCCGGGGAAC
  GCTCTGCCATGGGTGTGGGCAGCCCATCACTGGCCGTTGTATCAGTGCCATGGGGTACAAGTTCCATCCT
  GAGCACTTTGTGTGTGCTTTCTGCCTGACACAGTTGTCGAAGGGCATTTTCAGGGAGCAGAATGACAAGA
  CCTATTGTCAACCTTGCTTCAATAAGCTCTTCCCACTGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004811 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAAAGCTGTTCCTCACGGC
  CTGTGAGACAAGAGCATCTTGGATGTAGGACAATGGAAGAGTTAGATGCCTTATTGGAGG
  AACTGGAACGCTCCACCCTTCAGGACAGTGATGAATATTCCAACCCAGCTCCTCTTCCCC
  TGGATCAGCATTCCAGAAAGGAGACTAACCTTGATGAGACTTCGGAGATCCTTTCTATTC
  AGGATAACACAAGTCCCTTGCCGGCGCAGCTCGTGTATACTACCAATATCCAGGAGCTCA
  ATGTCTACAGTGAAGCCCAAGAGCCAAAGGAATCACCACCACCTTCTAAAACGTCAGCAG
  CTGCTCAGTTGGATGAGCTCATGGCTCACCTGACTGAGATGCAGGCCAAGGTTGCAGTGA
  GAGCAGATGCTGGCAAGAAGCACTTACCAGACAAGCAGGATCACAAGGCCTCCCTGGACT
  CAATGCTTGGGGGTCTCGAGCAGGAATTGCAGGACCTTGGCATTGCCACAGTGCCCAAGG
  GCCATTGTGCATCCTGCCAGAAACCGATTGCTGGGAAGGTGATCCATGCTCTAGGGCAAT
  CATGGCATCCTGAGCATTNTGTCTGTACTCATTGCAAAGAAGAGATTGGCTCCAGTCCCT
  TCTTTGAGCGGAGTGGCTTGGCCTACTGCCCCAACGACTACCACCAACTNTTTTCTCCAC
  GCTGTGCTTACTGCGCTGCTCCATCCTGGATAAGTGCTGACAGCNATGAACCAGACCTGG
  CACCCAGAGCACTTCTTCTGCTCTCACTGCGGAGAAGTGNTGGCTGCANAATGCTCTCAT
  GANAANGGACAGAAGCCATNNATGCCGAAGGATNNTCTAGCCATGTCCACCCAAGTGTGG
  TGGCTGCATCGCCCAGTGTGAGAAACTACCTTCACCATGGACCTGTCTGGCACCAAGTGC
  NTTGTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004811 unedited
  ATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTATTGAAACCACAAGCCAGTTTATTTA
  TCAATGATGTCAGTACTCAAAGTTGTCCAGTTAAAATCTACTTCCTCTTGAAAAACAAAA
  ATACACTGAAGGAAGATGCAAAGAGCTAAAAGTGGTATCATGATTCCACAGCAGTGATTG
  TAAGACAGTGAGCCACAGGGAAATGGGAAAACGTGAAAAGAAACAAGTATCAGGACCAAA
  TTAGAGAAGATATGAGTAGGGCCATCACTAGAGGTGAAAATGGAGAAACCTAAGAAAACC
  AGTGTTGGCATGAATTATGCAAGTGGAAAATACATCTGTAGAGGGACGAGATAGAAGGAC
  CTAGATCTAACTCCAAGTGCTTGATTGGAGAAGAGAGGGAGAAAGAGAATTTATAGAATT
  AACTGTATAGAAGCCTAAAAAATAAGATTATCAGCCTAGTCATGTAAAGTCTCTAGAAGT
  TCCTTTATTTGCTCATCACCTTTCCTTTTTCTATAAGACTATTAAGCAGAAGGTCAGTAA
  CAGAAAATTTACCCTTTCCTCTCCTCTCTTGGTTTAAATTTTATAAGGAATCTGAAGAGG
  CTATGGATCAGTTGGCATTACAGTGGGAAGAGCTTATTGAAAGCAGGGTTGACATAGGTC
  TTGGCATTTCTGCTCCNTGAAAATGCCCTTCGACCACTGTGTCAGGCAGNAAGCACACAC
  CAAGTGCTCAGGATGAAACTTGACCCCATGCCACTGATACAACGGCCAGTGATGGGCTGC
  CCACACCATGGCAGAGCGTCCCCGGCCGTGATGGAATGGAAGCTACCAGATGAACGTCCA
  TCCCGNTCAAAGAAGGAGCCAGTATAAAACTGGTGAGCAGTCCCCAAAACAAGCACTTTG
  TTGGCAAAAGTGTCCATGCTGAAAGGTATTTCCACCTGGGGGATGCGCCCCAACCTTGGT
  GGAACCTGCTAAATATCTTCGCAATGGCTTTTGCCTTTCAGAAGCTCTGCCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004811
• ORF Size: 1161 bp
• Insert Size: 1800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004811.1, NP_004802.1
• RefSeq Size: 1875
• RefSeq ORF: 1161
• Locus ID: 9404
• Domains: LIM
• Protein Families: Druggable Genome
• Gene Summary: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (2) uses an alternate 5' terminal exon, which results in a distinct 5' UTR and novel 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than and has a distinct N-terminus compared to isoform 1.