Leupaxin (LPXN) (NM_004811) Human Untagged Clone

CAT#: SC320429

LPXN (untagged)-Human leupaxin (LPXN), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LPXN
• Synonyms: LDPL
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004811.1 CTTCTTCAGCACATGCCAAAGCTGTTCCTCACGGCCTGTGAGACAAGAGCATCTTGGATG
  TAGGACAATGGAAGAGTTAGATGCCTTATTGGAGGAACTGGAACGCTCCACCCTTCAGGA
  CAGTGATGAATATTCCAACCCAGCTCCTCTTCCCCTGGATCAGCATTCCAGAAAGGAGAC
  TAACCTTGATGAGACTTCGGAGATCCTTTCTATTCAGGATAACACAAGTCCCTTGCCGGC
  GCAGCTCGTGTATACTACCAATATCCAGGAGCTCAATGTCTACAGTGAAGCCCAAGAGCC
  AAAGGAATCACCACCACCTTCTAAAACGTCAGCAGCTGCTCAGTTGGATGAGCTCATGGC
  TCACCTGACTGAGATGCAGGCCAAGGTTGCAGTGAGAGCAGATGCTGGCAAGAAGCACTT
  ACCAGACAAGCAGGATCACAAGGCCTCCCTGGACTCAATGCTTGGGGGTCTCGAGCAGGA
  ATTGCAGGACCTTGGCATTGCCACAGTGCCCAAGGGCCATTGTGCATCCTGCCAGAAACC
  GATTGCTGGGAAGGTGATCCATGCTCTAGGGCAATCATGGCATCCTGAGCATTTTGTCTG
  TACTCATTGCAAAGAAGAGATTGGCTCCAGTCCCTTCTTTGAGCGGAGTGGCTTGGCCTA
  CTGCCCCAACGACTACCACCAACTTTTTTCTCCACGCTGTGCTTACTGCGCTGCTCCCAT
  CCTGGATAAAGTGCTGACAGCAATGAACCAGACCTGGCACCCAGAGCACTTCTTCTGCTC
  TCACTGCGGAGAGGTGTTTGGTGCAGAAGGCTTTCATGAGAAGGACAAGAAGCCATATTG
  CCGAAAGGATTTCTTAGCCATGTTCTCACCCAAGTGTGGTGGCTGCAATCGCCCAGTGTT
  GGAAAACTACCTTTCAGCCATGGACACTGTCTGGCACCCAGAGTGCTTTGTTTGTGGGGA
  CTGCTTCACCAGTTTTTCTACTGGCTCCTTCTTTGAACTGGATGGACGTCCATTCTGTGA
  GCTCCATTACCATCACCGCCGGGGAACGCTCTGCCATGGGTGTGGGCAGCCCATCACTGG
  CCGTTGTATCAGTGCCATGGGGTACAAGTTCCATCCTGAGCACTTTGTGTGTGCTTTCTG
  CCTGACACAGTTGTCGAAGGGCATTTTCAGGGAGCAGAATGACAAGACCTATTGTCAACC
  TTGCTTCAATAAGCTCTTCCCACTGTAATGCCAACTGATCCATAGCCTCTTCAGATTCCT
  TATAAAATTTAAACCAAGAGAGGAGAGGAAAGGGTAAATTTTCTGTTACTGACCTTCTGC
  TTAATAGTCTTATAGAAAAAGGAAAGGTGATGAGCAAATAAAGGAACTTCTAGACTTTAC
  ATGACTAGGCTGATAATCTTATTTTTTAGGCTTCTATACAGTTAATTCTATAAATTCTCT
  TTCTCCCTCTCTTCTCCAATCAAGCACTTGGAGTTAGATCTAGGTCCTTCTATCTCGTCC
  CTCTACAGATGTATTTTCCACTTGCATAATTCATGCCAACACTGGTTTTCTTAGGTTTCT
  CCATTTTCACCTCTAGTGATGGCCCTACTCATATCTTCTCTAATTTGGTCCTGATACTTG
  TTTCTTTTCACGTTTTCCCATTTCCCTGTGGCTCACTGTCTTACAATCACTGCTGTGGAA
  TCATGATACCACTTTTAGCTCTTTGCATCTTCCTTCAGTGTATTTTTGTTTTTCAAGAGG
  AAGTAGATTTTAACTGGACAACTTTGAGTACTGACATCATTGATAAATAAACTGGCTTGT
  GGTTTAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004811.1 unedited
  GGCACTGTGTAGTACGACTCCTATAGTCGCGGCCGGGTAATTCGTCGACTGGATCCGGTA
  CCGAGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGG
  ACCGACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTG
  TAAAACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCG
  GCACGAGGCTTCTTCAGCACATGCCAAAGCTGTTCCTCACGGCCTGTGAGACAAGAGCAT
  CTTGGATGTAGGACAATGGAAGAGTTAGATGCCTTATTGGAGGAACTGGAACGCTCCACC
  CTTCAGGACAGTGATGAATATTCCAACCCAGCTCCTCTTCCCCTGGATCAGCATTCCAGA
  AAGGAGACTAACCTTGATGAGACTTCGGAGATCCTTTCTATTCAGGATAACACAAGTCCC
  TTGCCGGCGCAGCTCGTGTATACTACCAATATCCAGGAGCTCAATGTCTACAGTGAAGCC
  CAAGAGCCAAAGGAATCACCACCACCTTCTAAAACGTCAGCAGCTGCTCAGTTGGATGAG
  CTCATGGCTCACCTGACTGAGATGCAGGCCAAGGTTGCAGTGAGAGCAGATGCTGGCAAG
  AAGCACTTACCAGACAAGCAGGATCACAAAGGCCTCCCTGGACTCAATGCTTGGGGGTCT
  CGAGCAGGAATTGCAGGACCTTGGCATTGCCACAGTGCCCAAGGCCCATTGTGCATCCTG
  CCAGAACCGATTGCTGGGAAGGTGATCCATGCTCTAGGGCAATCATGCATCCTGAGCATT
  TTGTCTGTACTCATTGCAAAGAAGAGATTGGCTCCAGTCCTTCTTTGAGCGGAGTGGCTG
  ACCTACTGCCCACGACTACCACCACCTTTTTTCTCCAGCTGTGCTACTGGCGCTGCTCCA
  TCTGGATAAAGTGCTGC
• Restriction Sites: Please inquire
• ACCN: NM_004811
• ORF Size: 1161 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_004811.1, NP_004802.1
• RefSeq Size: 1875
• RefSeq ORF: 1161
• Locus ID: 9404
• Domains: LIM
• Protein Families: Druggable Genome
• Gene Summary: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (2) uses an alternate 5' terminal exon, which results in a distinct 5' UTR and novel 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than and has a distinct N-terminus compared to isoform 1.