ITGB1BP1 (NM_004763) Human Untagged Clone

CAT#: SC117162

ITGB1BP1 (untagged)-Human integrin beta 1 binding protein 1 (ITGB1BP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITGB1BP1
• Synonyms: ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117162 sequence for NM_004763 edited (data generated by NextGen Sequencing)
  ATGTTTCGCAAGGGCAAAAAACGACACAGTAGTAGCAGTTCCCAAAGTAGCGAAATCAGT
  ACTAAGAGCAAGTCTGTGGATTCTAGCCTTGGGGGTCTTTCACGATCCAGCACTGTGGCC
  AGCCTCGACACAGATTCCACCAAAAGCTCAGGACAAAGCAACAATAATTCAGATACCTGT
  GCAGAATTTCGAATAAAATATGTTGGTGCCATTGAGAAACTGAAACTCTCCGAGGGAAAA
  GGCCTTGAAGGGCCATTAGACCTGATAAATTATATAGACGTTGCCCAGCAAGATGGAAAG
  TTGCCTTTTGTTCCTCCGGAGGAAGAATTTATTATGGGAGTTTCCAAGTATGGCATAAAA
  GTATCAACATCAGATCAATATGATGTTTTGCACAGGCATGCTCTCTACTTAATAATCCGG
  ATGGTGTGTTACGATGACGGTCTGGGGGCGGGAAAAAGCTTACTGGCTCTGAAGACCACA
  GATGCAAGCAATGAGGAATACAGCCTGTGGGTTTATCAGTGCAACAGCCTGGAACAAGCA
  CAAGCCATTTGCAAGGTTTTATCCACCGCTTTTGACTCTGTATTAACATCTGAGAAACCC
  TGA
  
  Clone variation with respect to NM_004763.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004763 unedited
  NGGAAACGTTCAAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGC
  GCGGGCCGTTTCCTTGCCTCTTCCTCTGCCCCGCTTCGGCCGCCTCCCGCCTCTCAGGGT
  CGGGGTTGTCTGTCCCCTTCGCTGTCACATCCTCCGCACCCAGCGCTTGGAAGGTGCTCC
  ATCACGGTGACAGACAGGTGCCAAGCAGGCTGGCGTCTGGGAGGAACTTCGGAGCCGGCT
  CTCCCTAGGCCCCGAGCTTGGCCGCATCCGTCCTTACTCTGGTGACCCTGGGCAGGTCAC
  TGACTCTTCGGGCGCTTTGGCATCCTCGTTTGAAAGGGGCTGTTATCCTGCAGCCTTGCT
  GGTCGGTGAGGGTGAGGGTGAGAGGGATCTGTGCACCTAGCACCGTGCATGGCACGTGGT
  AGGCGTTTGGTACATGGGAATCGCTGTTGGGGTGTCACCTCCCCAGAAAGTTCTCGGCTT
  CAGTAAGCGCGTCCCCTGCCAGGCGCCCTGGCAATGCAGAGGAGTCACCGAGCTCCGCCT
  TTGACCAGCGTGCAGCTGGGAGAGTGAGATCAGAGACCACAGCAGATCGTGGCGCTGTGA
  TCAGGGGGTACACTCAAGCTGTGGGTCCCTTACCCCAGCCTTGAGATCCCAGGAAGGCCT
  GCAGCCTGAAACGGGCCTTGAAAGGGGATCTTCTCTGGATCAAGCAATGGTGGTGAAAAA
  ATGTTTCGCAGGGCAAAAAACGACACAGTAGTAGCAGTTCCCAAAGTAGCGAAATCAGTA
  CTAAGAGCAAGTCTGTGGATTCTAGCCTTGGGGGGTCTTTCACGATCCAGCACTGTGGCC
  AGCCTCGACACAGATTCCACCAAAAGCTCAGGACAAAGCAACAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004763 unedited
  TAGCTATGTACCGCGCGCCGCAATCTAGNGATCGGCTTTTTTTTTTTTTTTTTTCCCTGT
  GTAATAGGATACATTTTATAAACAAAGATCAGCATTTTACACAATCCATTTTCTTCAGAA
  AATCTAGAGCAAGGGATAACTTCATTATTTGCATAACATTTCAGCATTGCAGTTTGAAAA
  CAGCTGAACTTTCAGATGAAGTTGACTTCTACTTGATTGCAGGATTCAGGGTTTCTCAGA
  TGTTAATACAGAGTCAAAAGCGGTGGATAAAACCTTGCAAATGGCTTGTGCTTGTTCCAG
  GCTGTTGCACTGATAAACCCACAGGCTGTATTCCTCATTGCTTGCATCTGTGGTCTTCAA
  AGCCAGTAAGCTTTTTCCCGCCCCCAGACCGTCATCGTAACACACCATCCGGATTATTAA
  GTAGAGAGCATGCCTGTGCAAAACATCATATTGATCTGACGTTGATACTTTTATGCCATA
  CTTGGAAACTCCCATAATAAATTCTTCCTCCGGAGGAACAAAAGGCAACTTTCCATCTTG
  CTGGGCAACGTTTATATAATTTATCAGGTCTAACGGCCCCTTAAGGCCTTTTCCCTCGGA
  GAGTTTCAGTTTCTCATGGCCCCCACATATTTCATCCCCCATTCCCTGCCAGGTATTCTG
  AACAACTGCCGCTTCCCCCTCGACTTTTGGGGGAATCCGCTCAAAAGTTTGCCCCAGCCC
  TGGATCGTGAAATACCCCCATGCTTACACCTCCACCCTTCCTCTTATCCCGCCTTCGCTC
  CTTCGGACCTGTTCCCCCGCGCCCCTTCTCCCTTCGCAAAATCTCTACCCCCATCCCTCA
  CCCAAAAAATCCCCTTTAAGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004763
• ORF Size: 603 bp
• Insert Size: 1530
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_004763.2, NP_004754.1
• RefSeq Size: 1425
• RefSeq ORF: 603
• Locus ID: 9270
• Domains: PID
• Gene Summary: The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 3, 4, and 5 all encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.