ITGB1BP1 (NM_004763) Human Untagged Clone

CAT#: SC322415

ITGB1BP1 (untagged)-Human integrin beta 1 binding protein 1 (ITGB1BP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITGB1BP1
• Synonyms: ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322415 ACGGGAGTAGCTGCCTGGGCGCCAAAGGCCGCGGCACTCCCACGCGGACCCCGAAGTCCG
  CAACCCGGGGATGGGCCCGCGGCTGCGAGGGGATCTTCTCTGGATCAAGCAATGGTGGTG
  AAAAATGTTTCGCAAGGGCAAAAAACGACACAGTAGTAGCAGTTCCCAAAGTAGCGAAAT
  CAGTACTAAGAGCAAGTCTGTGGATTCTAGCCTTGGGGGTCTTTCACGATCCAGCACTGT
  GGCCAGCCTCGACACAGATTCCACCAAAAGCTCAGGACAAAGCAACAATAATTCAGATAC
  CTGTGCAGAATTTCGAATAAAATATGTTGGTGCCATTGAGAAACTGAAACTCTCCGAGGG
  AAAAGGCCTTGAAGGGCCATTAGACCTGATAAATTATATAGACGTTGCCCAGCAAGATGG
  AAAGTTGCCTTTTGTTCCTCCGGAGGAAGAATTTATTATGGGAGTTTCCAAGTATGGCAT
  AAAAGTATCAACATCAGATCAATATGATGTTTTGCACAGGCATGCTCTCTACTTAATAAT
  CCGGATGGTGTGTTACGATGACGGTCTGGGGGTGGGAAAAAGCTTACTGGCTCTGAAGAC
  CACAGATGCAAGCAATGAGGAATACAGCCTGTGGGTTTATCAGTGCAACAGCCTGGAACA
  AGCACAAGCCATTTGCAAGGTTTTATCCACCGCTTTTGACTCTGTATTAACATCTGAGAA
  ACCCTGAATCCTGCAATCAAGTAGAAGTCAACTTCATCTGAAAGTTCAGCTGTTTTCAAA
  CTGCAATGCTGAAATGTTATGCAAATAATGAAGTTATCCCTTGCTCTAGATTTTCTGAAG
  AAAATGGATTGTGTAAAATGCTGATCATTTGTTTATTAAAATGTGTCCTATTAAAAAAAA
  AAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322415 unedited
  GATCATTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGACGGGAGTAGCTGCCTGGGCGCCAAA
  GGCCGCGGCACTCCCACGCGGACCCCGAAGTCCGCAACCCGGGGATGGGCCCGCGGCTGC
  GAGGGGATCTTCTCTGGATCAAGCAATGGTGGTGAAAAATGTTTCGCAAGGGCAAAAAAC
  GACACAGTAGTAGCAGTTCCCAAAGTAGCGAAATCAGTACTAAGAGCAAGTCTGTGGATT
  CTAGCCTTGGGGGTCTTTCACGATCCAGCACTGTGGCCAGCCTCGACACAGATTCCACCA
  AAAGCTCAGGACAAAGCAACAATAATTCAGATACCTGTGCAGAATTTCGAATAAAATATG
  TTGGTGCCATTGAGAAACTGAAACTCTCCGAGGGAAAAGGCCTTGAAGGGCCATTAGACC
  TGATAAATTATATAGACGTTGCCCAGCAAGATGGAAAGTTGCCTTTTGTTCCTCCGGAGG
  AAGAATTTATTATGGGAGTTTCCAAGTATGGCATAAAAGTATCAACATCAGATCAATATG
  ATGTTTTGCACAGGCATGCTCTCTACTTAATAATCCGGATGGTGTGTTACGATGACGGTC
  TGGGGGTGGGAAAAAGCTTACTGGCTCTGAAGACCACAGATGCAAGCAATGAGAATACAG
  CCTGTGGGTTTATCAGTGCAACAGCCTGAACAGCACAAGCCATTTGCAAGTTTTATCCAC
  CGCTTTTGACTTTTGTATTACATCTGAGAAACCCTGAATCCTGCATCAGTAGAGTCACTT
  CATCTGAAAGTTCAGCTGTTTCAACTGCATGCTGAATGTTATGCAAATATGAGTTATCTG
  CTCTGAATTTCTGAAGAAAATGATGGGTAAATGCTGATCATTGTTATTAATGGTTTCTAT
  AAAAAAAAAAAGGGCGGCCCGCCACTTCTCAGCT
• Restriction Sites: Please inquire
• ACCN: NM_004763
• ORF Size: 603 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_004763.3, NP_004754.1
• RefSeq Size: 1930
• RefSeq ORF: 603
• Locus ID: 9270
• Domains: PID
• Gene Summary: The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 3, 4, and 5 all encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.