Calcipressin 1 (RCAN1) (NM_004414) Human Untagged Clone

CAT#: SC117406

RCAN1 (untagged)-Human regulator of calcineurin 1 (RCAN1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RCAN1
• Synonyms: ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004414 edited
  GAATTCGGCACGAGGGCCGGCCGGGCGCGGACCGGAGCGCGTGAGGCTCCGGCGCGCAAG
  CCCGGAGCAGCCCGCTGGGGCGCACAGGGTCGCGCGGGCGCGGGGATGGAGGACGGCGTG
  GCCGGTCCCCAGCTCGGGGCCGCGGCGGAGGCGGCGGAGGCGGCCGAGGCGCGAGCGCGG
  CCCGGGGTGACGCTGCGGCCCTTCGCGCCCCTCTCGGGGGCGGCCGAGGCGGACGAGGGC
  GGCGGCGACTGGAGCTTCATTGACTGCGAGATGGAGGAGGTGGACCTGCAGGACCTGCCC
  AGCGCCACCATCGCCTGTCACCTGGACCCGCGCGTGTTCGTGGACGGCCTGTGCCGGGCC
  AAATTTGAGTCCCTCTTTAGGACGTATGACAAGGACATCACCTTTCAGTATTTTAAGAGC
  TTCAAACGAGTCAGAATAAACTTCAGCAACCCCTTCTCCGCAGCAGATGCCAGGCTCCAG
  CTGCATAAGACTGAGTTTCTGGGAAAGGAAATGAAGTTATATTTTGCTCAGACCTTACAC
  ATAGGAAGCTCACACCTGGCTCCGCCAAATCCAGACAAGCAGTTTCTGATCTCCCCTCCC
  GCCTCTCCGCCAGTGGGATGGAAACAAGTGGAAGATGCGACCCCAGTCATAAACTATGAT
  CTCTTATATGCCATCTCCAAGCTGGGGCCAGGGGAAAAGTATGAATTGCACGCAGCGACT
  GACACCACTCCCAGCGTGGTGGTCCATGTATGTGAGAGTGATCAAGAGAAGGAGGAAGAA
  GAGGAAATGGAAAGAATGAGGAGACCTAAGCCAAAAATTATCCAGACCAGGAGGCCGGAG
  TACACGCCGATCCACCTCAGCTGAACTGGCACGCGACGAGGACGCATTCCAAATCATACT
  CACGGGAGGAATCTTTTACTGTGGAGGTGGCTGGTCACGACTTCTTCGGAGGTGGCAGCC
  GAGATCGGGGTGGCAGAAATCCCAGTTCATGTTGCTCAGAAGAGAATCAAGGCCGTGTCC
  CCTTGTTCTAATGCTGCACACCAGTTACTGTTCATGGCACCCGGGAATGACTTGGGCCAA
  TCACTGAGTTTGTGGTGATCGCACAAGGACATTTGGGACTGTCTTGAGAAAACAGATAAT
  GATAGTGTTTTGTACTTGTTCTTTTCTGGTAGGTTCTGTCTGTGCCAAGGGCAGGTTGAT
  CAGTGAGCTCAGGAGAGAGCTTCCTGTTTCTAAGTGGCCTGCAGGGGCCACTCTCTACTG
  GTAGGAAGAGGTACCACAGGAAGCCGCCTAGTGCAGAGAGGTTGTGAAAACAGCAGCAAT
  GCAATGTGGAAATTGTAGCGTTTCCTTTCTTCCCTCATGTTCTCATGTTTGTGCATGTAT
  ATTACTGATTTACAAGACTAACCTTTGTTCGTATATAAAGTTACACCGTTGTTGTTTTAC
  ATCTTTTGGGAAGCCAGGAAAGCGTTTGGAAAACGTATCACCTTTCCCAGATTCTCGGAT
  TCTCGACTCTTTGCAACAGCACTTGCTTGCGGAACTCTTCCTGGAATGCATTCACTCAGC
  ATCCCCAACCGTGCAACGTGTAACTTGTGCTTTTGCAAAAGAAGTTGATCTGAAATTCCT
  CTGTAGAATTTAGCTTATACAATTCAGAGAATAGCAGTTTCACTGCCAACTTTCAGTGGG
  TGAGAAATTTTAGTTTAGGTGTTTGGGATCGGACCTCAGTTTCTGTTGTTTCTTTTATGT
  GGTGGTTTCTATACATGAATCATAGCCAAAAACTTTTTTGGAAACTGTTGGTTGAGATAG
  TTGGTTCTTTTACCCCACGAAGACATCAAGATACACTTGTAAATAAAGCTGATAGCATAT
  ATTCATACCTGTTGTACACTTGGGTGAAAAGTATGGCAGTGGGAGACTAAGATGTATTAA
  CCTACCTGTGAATCATATGTTGTAGGAAAAGCTGTTCCCATGTCTAACAGGACTTGAATT
  CAAAGCATGTCAAGTGGATAGTAGATCTGTGGCGATATGAGAGGGATGCAGTGCCTTTCC
  CCATTCATTCCTGATGGAATTGTTATACTAGGTTAACATTTGTAATTTTTTTCTAGTTGT
  AATGTGTATGTCTGGTAAATAGGTATTATATTTTGGCCTTACAATACCGTAACAATGTTT
  GTCATTTTGAAATACTTAATGCCAAGTAACAATGCATGCTTTGGAAATTTGGAAGATGGT
  TTTATTCTTTGAGAAGCAAATATGTTTGCATTAAATGCTTTGATTGTTCATATCAAGAAA
  TTGATTGAACGTTCTCAAACCCTGTTTACGGTACTTGGTAAGAGGGAGCCGGTTTGGGAG
  AGACCATTGCATCGCTGTCCAAGTGTTTCTTGTTAAGTGCTTTTAAACTGGAGAGGCTAA
  CCTCAAAATATTTTTTTTAACTGCATTCTATAATAAATGGGCACAGTATGCTCCTTACAG
  AAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004414 unedited
  TGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGCCGGCCGGGCGCGGACC
  GGAGCGCGTGAGGCTCCGGCGCGCAAGCCCGGAGCAGCCCGCTGGGGCGCACAGGGTCGC
  GCGGGCGCGGGGATGGAGGACGGCGTGGCCGGTCCCCAGCTCGGGGCCGCGGCGGAGGCG
  GCGGAGGCGGCCGAGGCGCGAGCGCGGCCCGGGGTGACGCTGCGGCCCTTCGCGCCCCTC
  TCGGGGGCGGCCGAGGCGGACGAGGGCGGCGGCGACTGGAGCTTCATTGACTGCGAGATG
  GAGGAGGTGGACCTGCAGGACCTGCCCAGCGCCACCATCGCCTGTCACCTGGACCCGCGC
  GTGTTCGTGGACGGCCTGTGCCGGGCCAAATTTGAGTCCCTCTTTAGGACGTATGACAAG
  GACATCACCTTTCAGTATTTTAAGAGCTTCAAACGAGTCAGAATAAACTTCAGCAACCCC
  TTCTCCGCAGCAGATGCCAGGCTCCAGCTGCATAAGACTGAGTTTCTGGGAAAGGAAATG
  AAGTTATATTTTGCTCAGACCTTACACATAGGAAGCTCACACCTGGCTCCGCCAAATCCA
  GACAAGCAGTTTCTGATCTCCCCTCCCGCCTCTCCGCCAGTGGGATGGAAACAAGTGGAA
  GATGCGACCCCAGTCATAAACTATGATCTCTTATATGCCATCTCCAAGCTGGGGCCAGGG
  GAAAAGTATGAATTGCACGCAGCGACTGACACCACTCCCAGCGGGTGGTCCATTGTTGTG
  AGAGTGATCAANAAAGGAAGGAAAAAGAGAAATGGAAAGATGAGGAGACCTAGCCAAAAT
  ATCCAGACCAGAGCCGGAGTACCGCCCATCCACCTANCTGACTGCACGCGACAGGACGCA
  TTCAATATACTACGGGAGGATTTTTCTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004414 unedited
  NNNTTTTTGCTCTGCACCGCGCGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTC
  TGTAAGGAGCATACTGTGCCCATTTATTATAGAATGCAGTTAAAAAAAAATTTTGAGGTT
  AGCCTCTCCAGTTTAAAAGCACTTAACAAGAAACACTTGGACAGCGATGCACTGGTCTCT
  CCCAAACCGGCTCCCTCTTACCAAGTACCGTAAACAGGGTTTGAGAACGTTCAATCAATT
  TCTTGATATGAACAATCAAAGCATTTAATGCAAACATATTTGCTTCTCAAAGAATAAAAC
  CATCTTCCAAATTTCCAAAGCATGCATTGTTACTTGGCATTAAGTATTTCAAAATGACAA
  ACATTGTTACGGTATTGTAAGGCCAAAATATAATACCTATTTACCAGACATACACATTAC
  AACTAGAAAAAAATTACAAATGTTAACCTAGTATAACAATTCCATCAGGAATGAATGGGG
  AAAGGCACTGCATCCCTCTCATATCGCCACAGATCTACTATCCACTTGACATGCTTTGAA
  TTCAAGTCCTGTTAGACATGGGAACAGCTTTTCCTACAACATATGATTCACAGGTAGGTT
  AATACATCTTAGTCTCCCACTGCCATACTTTTCACCCAAGTGTACAACAGGTATGAATAT
  ATGCTATCAGCTTTATTTACAAGTGTATCTTGATGTCTTCGTGGGGTAAAAAACCAACTA
  TCTCAACCAACAGTTTCCAAAAAAGTTTTTGGCTATGATTCATGTATANGAACCCCCCCA
  TAAAAGAAACACCAGAACTGAGGTCCGATCCCAACACCTAAACTAAATTTTTCACCACTG
  AAAGTCGCACGTGAAACTGCTATTCTCTGAATTGTATAGCTAAATTCTACAGAGGATC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004414
• Insert Size: 2550 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004414.5, NP_004405.3
• RefSeq Size: 2457 bp
• RefSeq ORF: 759 bp
• Locus ID: 1827
• Cytogenetics: 21q22.12
• Domains: Calcipressin
• Protein Families: Transcription Factors
• Gene Summary: 'The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).