Angiotensinogen (AGT) (NM_000029) Human Untagged Clone

CAT#: SC117553

AGT (untagged)-Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)


  "NM_000029" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol AGT
Synonyms ANHU; hFLT1; SERPINA8
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC117553 sequence for NM_000029 edited (data generated by NextGen Sequencing)
ATGCGGAAGCGAGCACCCCAGTCTGAGATGGCTCCTGCCGGTGTGAGCCTGAGGGCCACC
ATCCTCTGCCTCCTGGCCTGGGCTGGCCTGGCTGCAGGTGACCGGGTGTACATACACCCC
TTCCACCTCGTCATCCACAATGAGAGTACCTGTGAGCAGCTGGCAAAGGCCAATGCCGGG
AAGCCCAAAGACCCCACCTTCATACCTGCTCCAATTCAGGCCAAGACATCCCCTGTGGAT
GAAAAGGCCCTACAGGACCAGCTGGTGCTAGTCGCTGCAAAACTTGACACCGAAGACAAG
TTGAGGGCCGCAATGGTCGGGATGCTGGCCAACTTCTTGGGCTTCCGTATATATGGCATG
CACAGTGAGCTATGGGGCGTGGTCCATGGGGCCACCGTCCTCTCCCCAACGGCTGTCTTT
GGCACCCTGGCCTCTCTCTATCTGGGAGCCTTGGACCACACAGCTGACAGGCTACAGGCA
ATCCTGGGTGTTCCTTGGAAGGACAAGAACTGCACCTCCCGGCTGGATGCGCACAAGGTC
CTGTCTGCCCTGCAGGCTGTACAGGGCCTGCTAGTGGCCCAGGGCAGGGCTGATAGCCAG
GCCCAGCTGCTGCTGTCCACGGTGGTGGGCGTGTTCACAGCCCCAGGCCTGCACCTGAAG
CAGCCGTTTGTGCAGGGCCTGGCTCTCTATACCCCTGTGGTCCTCCCACGCTCTCTGGAC
TTCACAGAACTGGATGTTGCTGCTGAGAAGATTGACAGGTTCATGCAGGCTGTGACAGGA
TGGAAGACTGGCTGCTCCCTGATGGGAGCCAGTGTGGACAGCACCCTGGCTTTCAACACC
TACGTCCACTTCCAAGGGAAGATGAAGGGCTTCTCCCTGCTGGCCGAGCCCCAGGAGTTC
TGGGTGGACAACAGCACCTCAGTGTCTGTTCCCATGCTCTCTGGCATGGGCACCTTCCAG
CACTGGAGTGACATCCAGGACAACTTCTCGGTGACTCAAGTGCCCTTCACTGAGAGCGCC
TGCCTGCTGCTGATCCAGCCTCACTATGCCTCTGACCTGGACAAGGTGGAGGGTCTCACT
TTCCAGCAAAACTCCCTCAACTGGATGAAGAAACTGTCTCCCCGGACCATCCACCTGACC
ATGCCCCAACTGGTGCTGCAAGGATCTTATGACCTGCAGGACCTGCTCGCCCAGGCTGAG
CTGCCCGCCATTCTGCACACCGAGCTGAACCTGCAAAAATTGAGCAATGACCGCATCAGG
GTGGGGGAGGTGCTGAACAGCATTTTTTTTGAGCTTGAAGCGGATGAGAGAGAGCCCACA
GAGTCTACCCAACAGCTTAACAAGCCTGAGGTCTTGGAGGTGACCCTGAACCGCCCATTC
CTGTTTGCTGTGTATGATCAAAGCGCCACTGCCCTGCACTTCCTGGGCCGCGTGGCCAAC
CCGCTGAGCACAGCATGA

Clone variation with respect to NM_000029.3
1116 a=>g
>OriGene 5' read for NM_000029 unedited
GTGTGCACTATTTTGTNAATACGACNCACTTATAGGGCGGCCGCGATTCGGCACGAGGTT
GTTCTGGGTACTACAGCAGAAGGGTATGCGGAAGCGAGCACCCCAGTCTGAGATGGCTCC
TGCCGGTGTGAGCCTGAGGGCCACCATCCTCTGCCTCCTGGCCTGGGCTGGCCTGGCTGC
AGGTGACCGGGTGTACATACACCCCTTCCACCTCGTCATCCACAATGAGAGTACCTGTGA
GCAGCTGGCAAAGGCCAATGCCGGGAAGCCCAAAGACCCCACCTTCATACCTGCTCCAAT
TCAGGCCAAGACATCCCCTGTGGATGAAAAGGCCCTACAGGACCAGCTGGTGCTAGTCGC
TGCAAAACTTGACACCGAAGACAAGTTGAGGGCCGCAATGGTCGGGATGCTGGCCAACTT
CTTGGGCTTCCGTATATATGGCATGCACAGTGAGCTATGGGGCGTGGTCCATGGGGCCAC
CGTTCTCTCCCCAACGGCTGTCTTTGGCACCCTGGCCTCTCTCTATCTGGGAGCCTTGGA
CCACACAGCTGACAGGCTACAGGCAATCCTGGGTGTTCCTTGGAAGGACAAGAACTGCAC
CTCCCCGGCTGGATGCGCACAAGGCCCCTGTCTGCCCTGCAGGCTGTACAGGGCCCTGCT
AATGGCCCAAGGCAGGGCTGATAGCCAGGCCCAGCTGCTGCTGTCCACGTGGTGGGCGTG
TTCACACTCCCAGCCTGCACTCGAACCACCGTTTGTGCAGGCCCTGCTTTCTATAACCCC
TGAGGTCCTCCACCCTCTCTGGACTTCACAAAATGGATGTGCCGCTGACAAAAGGCAGGT
TCATGCCCCCTGTGCACCGAAGGAAGACCGGCTGTTCCCTGATGGGACCACCGTGGAACA
CACACCTGCCTT
>OriGene 3' read for NM_000029 unedited
GGCAACTTTCCAGGGCCAGGNATAGCACTGGGGAGGGGTCACAGGGCAGCCACCCGGGAT
CTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT
TTTGTGGCAAGACGTTTATTACTAACACAAGGGAGAAATAACCAGCTATTGTTCCGCATT
CAAACAGAAATTCAGGTGCTTGCATCTTTCACGTATTGGTCAAAAATCACAAGCATCTGT
GGAAAAAACTAAGGTATTACAGACACTACACGGAGGTCATGTTCTTACATTCAAGACACT
AAATACAAACCGAAGGCAATGCAAAAATGTATACTTTAATTTTAAAACCCAATTTTTGTT
CTCAACTTGAAAAGGGAACACTTTTTTGTTTCACAAACAAGCTGGTCGGTTGGAATTCTT
TTTGGAACAGTAGTCCCGCGCTAAACACTGGTTCTTGCCTCCCCACCCCCATTCTCTAAA
ATAAACCCAGCAAACTGGGAGGTGCATTTGTGCCGCTGCAGGCTTCTACTGCTCACTCCA
TGCAGCACACTTAGACCAAGGAGAAACGGCTGCTTTCCAGCTCAAAGTCGACTATTAAAA
GAAAAGGTGGGAGACTGGGGGTGACCATCCTGATTGTCCCCGGGGGGTGGTATCTGGCTG
CTGGCCTTTGCCTCAAAGCCAAGGGCAAAAGCCTTGCAGCAACTGGGTTTTTGGGGGGCC
TGGCTCATGCTGGCTAAAGGGGGTTGGCCCCCCGCCCACAAAAGCAGGGGCAATGGGGCT
TTTTAATCTCCACACAGAAAGGGGGGGGGTTGGAGGCCCCCCCCAACCTAGGCTGTAAAA
GCCGGGGGGGAAACCTTGGGGGGCCTCTTATAACGGTAAGCCAAAAAAGGCGG
Restriction Sites NotI-NotI     
ACCN NM_000029
Insert Size 2050 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000029.2, NP_000020.1
RefSeq Size 2192 bp
RefSeq ORF 1458 bp
Locus ID 183
Cytogenetics 1q42.2
Domains SERPIN
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Renin-angiotensin system
Gene Summary 'The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019]'

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