Annexin A2 (ANXA2) (NM_004039) Human Untagged Clone

CAT#: SC117624

ANXA2 (untagged)-Human annexin A2 (ANXA2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANXA2
• Synonyms: ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117624 sequence for NM_004039 edited (data generated by NextGen Sequencing)
  ATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCC
  CCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTG
  AACATTGAAACAGCCATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTG
  ACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAA
  AAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTG
  GGCCTATTGAAGACACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGG
  CTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTG
  CAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATT
  TCGGACACATCTGGTGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCA
  GAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGGATCTCTATGAC
  GCTGGAGTGAAGAGGAAAGGAACTGATGTTCCCAAGTGGATCAGCATCATGACCGAGCGG
  AGCGTGCCCCACCTCCAGAAAGTATTTGATAGGTACAAGAGTTACAGCCCTTATGACATG
  TTGGAAAGCATCAGGAAAGAGGTTAAAGGAGACCTGGAAAATGCTTTCCTGAACCTGGTT
  CAGTGCATTCAGAACAAGCCCCTGTATTTTGCTGATCGGCTGTATGACTCCATGAAGGGC
  AAGGGGACGCGAGATAAGGTCCTGATCAGAATCATGGTCTCCCGCAGTGAAGTGGACATG
  TTGAAAATTAGGTCTGAATTCAAGAGAAAGTACGGCAAGTCCCTGTACTATTATATCCAG
  CAAGACACTAAGGGCGACTACCAGAAAGCGCTGCTGTACCTGTGTGGTGGAGATGACTGA
  
  Clone variation with respect to NM_004039.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004039 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGACGCTCTCAGCTC
  TCGGCGCACGGCCCAGCTTCCTTCAAAAGTCTACTGTTCACGAAATCCTGTGCAAGCTCA
  GCTTGGAGGGTGATCACTCTACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTA
  ACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGCCATCAAGACCAAAGGTGTGG
  ATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTG
  CCTTCGCCTACCAGAGAAGGACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTAT
  CTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGACACCTGCTCAGTATGACGCTT
  CTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCA
  TCTGCTCCAGAACCAACCAGGAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACA
  AGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGGTGACTTCCGCAAGCTGATGG
  TTGCCCTGNCAAAGGGTAAAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTG
  ACCAAGATGCTCGGGATCTCTATGACGCTGNAGTGAAGAGGAAGGAACTGATGNTCCCAA
  GTGGATCAGCATCATGACCGAGCGGAGCGTGCCCCACCTNCAGAAAGTATTTGATAGGTA
  CAAGAAGTACAGCCCTTATGACATGTTTGGAAGCATCANGNAAGAGTTAAAAGGAGACCT
  GGAAAATGCCTTTCCTGAACCCTGGTCAGTGCATTCAGAACAAGCCCCTGTATTTTGCTG
  ATCCGCTGAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004039 unedited
  GTCATATATCCTCTGTTTATGACACAGTACACAGCGNAGGCAAAGTGTTTCACATCATAT
  ACTTCACTTCCAACTCCTATGGATGTTCATTTCTTTGGCTTACAGGAGAGACTAGACAGG
  AAGGCCAGGCAATGCTTATGCAACTAAAATGAGGTTGGGGGTAATGCTAACGTCACCCTC
  ACAGGGATGGCCACGGGGACTGTTATTCGCAAGCTGGTTTTCTAGACCTGTTAGCTGGAA
  GCATGGTGAGCACCATTTCTGGACGCTCATGCCGTGTCGGGCTTCATTCATCTCCACCAC
  ACATGTACATCAGCGCTTTCTGGTAGTCGCCCTTAGTGTCTTGCTGGATATAATAGTACA
  GGGACTTGCCGCACTTTCTCTTGAATTCAGACCTAATTTTCAACATGTTCACTTCACCTG
  CGGGAAACCATGATTCTGACCAGGACCTTATCTCCCGTTCCCTTGGCCTTAATTGAAGAC
  TTCAACCCATCACAAAAATCATGGGCCTGTCCCCTACCCCGTACCATTTCATACAATATT
  TCTCAACTTTCTTAAACCCTCCCCCTAGCTCCCCCATTTAATATGGCTGATACTCTGCCC
  ATTAATTCCCTCCAGAGGGGGACCCCCCCGTCGTTTTTATTCTACCCACTCGGACACTCC
  CGTCCTTCTCTTCCTCATCTTATCCATATCAATCTCCCTTCTCTTCCCACTCTTTCACCG
  CACACGCCCTTCAGTCCTCTCTTCACTTCTCTCTCCCCTCTCTTACTTTATATCCTCCAC
  CCTTCTTACTTATCCCTCTCCTCTCTACCCCCCAAACACACTCACTCCCTATTTCTTCTT
  TTCTTATTCATGTCTGCCCTTTTTTCTTCTTCCACATTTAAGTCATTTTGGTCTCCCTTT
  CACCCTGATCTATCATTCCTCAACTCATTCTTTTTCGAGTTCCAACCACGAACCCATTCA
  TCATACTATTCTCTTAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004039
• Insert Size: 1540 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004039.2, NP_004030.1
• RefSeq Size: 1563 bp
• RefSeq ORF: 1020 bp
• Locus ID: 302
• Cytogenetics: 15q22.2
• Domains: annexin
• Protein Families: Druggable Genome, Secreted Protein, Stem cell - Pluripotency
• Gene Summary: 'This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019]'
  Transcript Variant: This variant (3) lacks a segment in the 5' region, as compared to variant 1. It uses a downstream AUG start codon and encodes isoform 2 which has a shorter N-terminus, as compared to isoform 1. Variants 2, 3 and 4 encode the same isoform (2).