GMP Synthase (GMPS) (NM_003875) Human Untagged Clone

CAT#: SC117688

GMPS (untagged)-Human guanine monphosphate synthetase (GMPS)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GMPS
• Synonyms: GATD7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117688 sequence for NM_003875 edited (data generated by NextGen Sequencing)
  ATGGCTCTGTGCAACGGAGACTCCAAGCTGGAGAATGCTGGAGGAGACCTTAAGGATGGC
  CACCACCACTATGAAGGAGCTGTTGTCATTCTGGATGCTGGTGCTCAGTACGGGAAAGTC
  ATAGACCGAAGAGTGAGGGAACTGTTCGTGCAGTCTGAAATTTTCCCCTTGGAAACACCA
  GCATTTGCTATAAAGGAACAAGGATTCCGTGCTATTATCATCTCTGGAGGACCTAATTCT
  GTGTATGCTGAAGATGCTCCCTGGTTTGATCCAGCAATATTCACTATTGGCAAGCCTGTT
  CTTGGAATTTGCTATGGTATGCAGATGATGAATAAGGTATTTGGAGGTACTGTGCACAAA
  AAAAGTGTCAGAGAAGATGGAGTTTTCAACATTAGTGTGGATAATACATGTTCATTATTC
  AGGGGCCTTCAGAAGGAAGAAGTTGTTTTGCTTACACATGGAGATAGTGTAGACAAAGTA
  GCTGATGGATTCAAGGTTGTGGCACGTTCTGGAAACATAGTAGCAGGCATAGCAAATGAA
  TCTAAAAAGTTATATGGAGCACAGTTCCACCCTGAAGTTGGCCTTACAGAAAATGGAAAA
  GTAATACTGAAGAATTTCCTTTATGATATAGCTGGATGCAGTGGAACCTTCACCGTGCAG
  AACAGAGAACTTGAGTGTATTCGAGAGATCAAAGAGAGAGTAGGCACGTCAAAAGTTTTG
  GTTTTACTCAGTGGTGGAGTAGACTCAACAGTTTGTACAGCTTTGCTAAATCGTGCTTTG
  AACCAAGAACAAGTCATTGCTGTGCACATTGATAATGGCTTTATGAGAAAACGAGAAAGC
  CAGTCTGTTGAAGAGGCCCTCAAAAAGCTTGGAATTCAGGTCAAAGTGATAAATGCTGCT
  CATTCTTTCTACAATGGAACAACAACCCTACCAATATCAGATGAAGATAGAACCCCACGG
  AAAAGAATTAGCAAAACGTTAAATATGACCACAAGTCCTGAAGAGAAAAGAAAAATCATT
  GGGGATACTTTTGTTAAGATTGCCAATGAAGTAATTGGAGAAATGAACTTGAAACCAGAG
  GAGGTTTTCCTTGCCCAAGGTACTTTACGGCCTGATCTAATTGAAAGTGCATCCCTTGTT
  GCAAGTGGCAAAGCTGAACTCATCAAAACCCATCACAATGACACAGAGCTCATCAGAAAG
  TTGAGAGAGGAGGGAAAAGTAATAGAACCTCTGAAAGATTTTCATAAAGATGAAGTGAGA
  ATTTTGGGCAGAGAACTTGGACTTCCAGAAGAGTTAGTTTCCAGGCATCCATTTCCAGGT
  CCTGGCCTGGCAATCAGAGTAATATGTGCTGAAGAACCTTATATTTGTAAGGACTTTCCT
  GAAACCAACAATATTTTGAAAATAGTAGCTGATTTTTCTGCAAGTGTTAAAAAGCCACAT
  ACCCTATTACAGAGAGTCAAAGCCTGCACAACAGAAGAGGATCAGGAGAAGCTGATGCAA
  ATTACCAGTCTGCATTCACTGAATGCCTTCTTGCTGCCAATTAAAACTGTAGGTGTGCAG
  GGTGACTGTCGTTCCTACAGTTACGTGTGTGGAATCTCCAGTAAAGATGAACCTGACTGG
  GAATCACTTATTTTTCTGGCTAGGCTTATACCTCGCATGTGTCACAACGTTAACAGAGTT
  GTTTATATATTTGGCCCACCAGTTAAAGAACCTCCTACAGATGTTACTCCCACTTTCTTG
  ACAACAGGGGTGCTCAGTACTTTACGCCAAGCTGATTTTGAGGCCCATAACATTCTCAGG
  GAGTCTGGGTATGCTGGGAAAATCAGCCAGATGCCGGTGATTTTGACACCATTACATTTT
  GATCGGGACCCACTTCAAAAGCAGCCTTCATGCCAGAGATCTGTGGTTATTCGAACCTTT
  ATTACTAGTGACTTCATGACTGGTATACCTGCAACACCTGGCAATGAGATCCCTGTAGAG
  GTGGTATTAAAGATGGTCACTGAGATTAAGAAGATTCCTGGTATTTCTCGAATTATGTAT
  GACTTAACATCAAAGCCCCCAGGAACTACTGAGTGGGAGTAA
  
  Clone variation with respect to NM_003875.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003875 unedited
  GGTTGTCACATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCTGGT
  CTTCTCTCCCGCGGCGCTGGGGCCCGCGCTCCGCTGCTGTTGCTCCATTCGGCGCTTTTC
  TGGCGGCTGGCTCCTCTCCGCTGCCGGCTGCTCCTCGACCAGGCCTCCTTCTCAACCTCA
  GCCCGCGGCGCCGACCCTTCCGGCACCCTCCCGCCCCGTCTCGTACTGTCGCCGTCACCG
  CCGCGGCTCCGGCCCTGGCCCCGATGGCTCTGTGCAACGGAGACTCCAAGCTGGAGAATG
  CTGGAGGAGACCTTAAGGATGGCCACCACCACTATGAAGGAGCTGTTGTCATTCTGGATG
  CTGGTGCTCAGTACGGGAAAGTCATAGACCGAAGAGTGAGGGAACTGTTCGTGCAGTCTG
  AAATTTTCCCCTTGGAAACACCAGCATTTGCTATAAAGGAACAAGGATTCCGTGCTATTA
  TCATCTCTGGAGGACCTAATTCTGTGTATGCTGAAGATGCTCCCTGGTTTGATCCAGCAA
  TATTCACTATTGGCAAGCCTGTTCTTGGAATTTGCTATGGTATGCAGATGATGAATAAGG
  TATTTGGAGGTACTGTGCACAAAAAAAGTGTCAGAGAAGATGGAGTTTTCAACATTAGTG
  TGGATAATACATGTTCATTATTCAGGGGCCTTCAGAAGGAAGAAGTTGTTTTGCTTACAC
  ATGGAGATAGTGTAGACAAAGTAGCTGATGGATTCAAGGTTGTGGCACGTTCTGGAAACA
  TAGTAGCAGGCATAGCANATGAATCTAAAAAGTTATATGGGAGCACAGTTNCACCCCTGA
  AGNTGGCCTTACANGAAATGGNNAAAGTATACTGAAGAATTTCCTTTATGATATAGCTGG
  ATGCAGTGGAACCTTCACGTGCAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003875 unedited
  GTACCGCGGCACGCAATCTAGTGTCGAGTTTTTTTTTTTTTTTTTTACTTTAATAGAACA
  AGAAGTTTATTACTCCCACTCAGTAGTTCCTGGGGGCTTTGATGTTAAGTCATACATAAT
  TCGAGAAATACCAGGAATCTTCTTAATCTCAGTGACCATCTTTAATACCACCTCTACAGG
  GATCTCATTGCCAGGTGTTGCAGGTATACCAGTCATGAAGTCACTAGTAATAAAGGTTCG
  AATAACCACAGATCTCTGGCATGAAAGCTGCTTTTGAAGTGGGTCCCGATCAAAATGTAA
  TGGTGTCAAAATCACCGGCATCTGGCTGATTTTCCCAGCATACCCAGACTCCCTGAGAAT
  GTTATGGGCCTCAAAATCAGCTTGGCGTAAAGTACTGAGCACCCCTGTTGTCAAGATAGT
  GGGAGTAACATCTGTAAGAGGTTCTTTAACTGGTGGGCCAAATATATAAACAACTCTGTT
  AACGTTGTGACACATGCGATGTATAAGCCTAGCCAGATAATAAGTGATTCCCAGTCAGGT
  TCATCTTTACTGGAGATTCCACACACGTAACTGTAAGAACGACAGTCACCCTGCACACCT
  ACAGTTNTAATTGGCAGCAAGATAGCATTCAGTGAATGCAGACTGGTAATTTGCATCAGC
  TTCTCCTGATCCTCTTCTAGTGTGCAAGCTTTGACTCTCTGTAATAAGGTATGTAGGCTT
  TTTAACACTTGCAGAAAATCAGCTACTATTTTCAAATATTGGTAGGTTCAGGAAAATCCT
  TACAATATAAAGTNTTCAGCACATATTACTCTGATTGCCANGCCAGGACCCTGGAATGGA
  TGCCCTGGAACTAACTCTTCTGGAAGTCCAGTTCTCTGCCCAAATTCCACCTCATCTTAT
  GAAAATCTTCAAAGTNCTATTACTTTTCCCTCCTCTCTAACTTCTGATGGCTCTGGGCCA
  TGGGATGGCCTTTGAGAGNTCACTCTTGCACCGGCAACAGGGATGCACTTNNCATANATC
  AGGCCGTAAGACN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003875
• ORF Size: 2082 bp
• Insert Size: 2440
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003875.2, NP_003866.1
• RefSeq Size: 2457
• RefSeq ORF: 2082
• Locus ID: 8833
• Domains: GATase, GMP_synt_C
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
• Gene Summary: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]