DYNLL1 (NM_003746) Human Untagged Clone

CAT#: SC117803

DYNLL1 (untagged)-Human dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DYNLL1
• Synonyms: DLC1; DLC8; DNCL1; DNCLC1; hdlc1; LC8; LC8a; PIN
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117803 sequence for NM_003746 edited (data generated by NextGen Sequencing)
  ATGTGCGACCGAAAGGCCGTGATCAAAAATGCGGACATGTCGGAAGAGATGCAACAGGAC
  TCGGTGGAGTGCGCTACTCAGGCGCTGGAGAAATACAACATAGAGAAGGACATTGCGGCT
  CATATCAAGAAGGAATTTGACAAGAAGTACAATCCCACCTGGCATTGCATCGTGGGGAGG
  AACTTCGGTAGTTATGTGACACATGAAACCAAACACTTCATCTACTTCTACCTGGGCCAA
  GTGGCCATTCTTCTGTTCAAATCTGGTTAA
  
  Clone variation with respect to NM_003746.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003746 unedited
  TTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTTCGGTAGCGACG
  GTAGCTCTAGCCGGGCCTGAGCTGTGCTAGCACCTCCCCCAGGAGACCGTTGCAGTCGGC
  CAGCCCCCTTCTCCACGGTAACCATGTGCGACCGAAAGGCCGTGATCAAAAATGCGGACA
  TGTCGGAAGAGATGCAACAGGACTCGGTGGAGTGCGCTACTCAGGCGCTGGAGAAATACA
  ACATAGAGAAGGACATTGCGGCTCATATCAAGAAGGAATTTGACAAGAAGTACAATCCCA
  CCTGGCATTGCATCGTGGGGAGGAACTTCGGTAGTTATGTGACACATGAAACCAAACACT
  TCATCTACTTCTACCTGGGCCAAGTGGCCATTCTTCTGTTCAAATCTGGTTAAAAGCATG
  GACTGTGCCACACACCCAGTGATCCATCCAAAAACAAGGACTGCAGCCTAAATTCCAAAT
  ACCAGAGACTGAAATTTTCAGCCTTGCTAAGGGAACATCTCGATGTTTGAACCTTTGTTG
  TGTTTTGTACAGGGCATTCTCTGTACTAGTTTGTCGTGGTTATAAAACAATTAGCAGAAT
  AGCCTACATTTGTATTTATTTTCTATTCCATACTTCTGCCCACGTTGTTTTCTCTCAAAA
  TCCATTCCTTTAAAAAATAAATCTGATGCAGATGTGTAAAAAAAAAAAAAAAAAACTCGA
  CTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGT
  GACCCTNCCCAGTGCCTCTCCTGGCCCTGAAGTTGCCACTCCAGTGCCCACCAGNCCTTG
  TCTATAAAATTAAGTGCATCATTTTGCTGACTAGGTGTCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003746 unedited
  GAGTCGAGTTTTTTTTTTTTTTTTTTTACACATCTGCATCAGATTTATTTTTTAAAGGAA
  TGGATTTTGAGAGAAAACAACGTGGGCAGAAGTATGGAATAGAAAATAAATACAAATGTA
  GGCTATTCTGCTAATTGTTTTATAACCACGACAAACTAGTACAGAGAATGCCCTGTACAA
  AACACAACAAAGGTTCAAACATCGAGATGTTCCCTTAGCAAGGCTGAAAATTTCAGTCTC
  TGGTATTTGGAATTTAGGCTGCAGTCCTTGTTTTTGGATGGATCACTGGGTGTGTGGCAC
  AGTCCATGCTTTTAACCAGATTTGAACAGAAGAATGGCCACTTGGCCCAGGTAGAAGTAG
  ATGAAGTGTTTGGTTTCATGTGTCACATAACTACCGAAGTTCCTCCCCACGATGCAATGC
  CAGGTGGGATTGTACTTCTTGTCAAATTCCTTCTTGATATGAGCCGCAATGTCCTTCTCT
  ATGTTGTATTTCTCCAGCGCCTGAGTAGCGCACTCCACCGAGTCCTGTTGCATCTCTTCC
  GACATGTCCGCATTTTTGATCACGGCCTTTTNGTCGCACATGGGTACCGTGGAGAAGGNG
  GCTGGCCGACTGCACCGTCTCCTGGGGAAGTGCTACACAGCTAGGCCCGGCTGAGCTACG
  TCGCTACCGAACCCTCGTGCCGAATTCCGGCCGCCCTAAATGAGTCGTATACCAAATCCT
  TGACGTTCACTAACGAGCTCTGGTATATAGACCTTCCACCGACACCCCTACCGGCATTTG
  CGTAACCGGGGCCGGGTTTTACCAAATTTTGAAAGTCCGGTGGATTTTGGTGCCAAACAA
  CTTCCATGGACGCAATGGGGGGAAACTGGAAATCCCCTGAGTAAACCGCTTTCACCCCTT
  GGGTGTTGCCAAACCGATACCTGGTAAAACCAGACTAACCTTAAGTCTGCCAATTGAAAG
  CCCCAAGGTATATTGGCTAATGCCAGGGGCCTTCACGCTTGCCTATAAGGGCGGCTTGCT
  ATAACACTTAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003746
• ORF Size: 270 bp
• Insert Size: 700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003746.1, NP_003737.1
• RefSeq Size: 643
• RefSeq ORF: 270
• Locus ID: 8655
• Domains: Dynein_light
• Gene Summary: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) contains a distinct 5' UTR, including an alternate, downstream transcription initiation site. Variants 1, 2 and 3 encode the same protein.