AKR7A2 (NM_003689) Human Untagged Clone

CAT#: SC117811

AKR7A2 (untagged)-Human aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKR7A2
• Synonyms: AFAR; AFAR1; AFB1-AR1; AKR7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003689, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTGAGTGCCGCGTCTCGCGTAGTCTCCCGCGCCGCCGTCCACTGCGCGCTTCGCTCTCCGCCGCCCG
  AGGCCCGCGCGCTCGCCATGTCCCGGCCACCGCCACCGCGGGTCGCCTCGGTGCTGGGCACCATGGAGAT
  GGGGCGCCGCATGGACGCGCCCGCCAGCGCCGCGGCCGTGCGCGCCTTTCTGGAGCGCGGCCACACCGAA
  CTGGACACGGCCTTCATGTACAGCGACGGCCAGTCCGAGACCATCCTGGGCGGCCTGGGGCTCGGGCTGG
  GCGGTGGCGACTGCAGAGTGAAAATTGCCACCAAGGCCAACCCTTGGGATGGAAAATCACTAAAGCCTGA
  CAGTGTCCGGTCCCAGCTGGAGACGTCATTGAAGAGGCTGCAGTGTCCCCAAGTGGACCTCTTCTACCTA
  CACGCACCTGACCACGGCACCCCGGTGGAAGAGACGCTGCATGCCTGCCAGCGGCTGCACCAGGAGGGCA
  AGTTCGTGGAGCTTGGCCTCTCCAACTATGCTAGCTGGGAAGTGGCCGAGATCTGTACCCTCTGCAAGAG
  CAATGGCTGGATCCTGCCCACTGTGTACCAGGGCATGTACAACGCCACCACCCGGCAGGTGGAAACGGAG
  CTCTTCCCCTGCCTCAGGCACTTTGGACTGAGGTTCTATGCCTACAACCCTCTGGCTGGGGGCCTGCTGA
  CTGGCAAGTACAAGTATGAGGACAAGGACGGGAAACAGCCTGTGGGCCGCTTCTTTGGGAATAGCTGGGC
  TGAGACCTACAGGAATCGCTTCTGGAAGGAGCACCACTTCGAGGCCATTGCGTTGGTGGAGAAGGCCCTG
  CAGGCCGCATATGGCGCCAGCGCCCCCAGTGTGACCTCGGCTGCCCTCCGGTGGATGTACCACCACTCAC
  AGCTGCAGGGTGCCCACGGGGACGCGGTCATCCTGGGCATGTCCAGCCTGGAGCAGCTGGAGCAGAACTT
  GGCAGCAACAGAGGAAGGGCCCCTGGAGCCGGCTGTCGTGGATGCCTTTAATCAAGCCTGGCATTTGGTT
  GCTCACGAATGTCCCAACTACTTCCGCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003689 unedited
  GGTCAAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGTCTCCCGTT
  GCCGCCGTCATGTCCCGGCAGCTGTCGCGGGCCCGGCCAGCCACGGTGCTGGGCGCCATG
  GAGATGGGGCGCCGCATGGACGCGCCCACCAGCGCCGCAGTCACGCGCGCCTTCCTGGAG
  CGCGGCCACACCGAGATAGACACGGCCTTCGTGTACAGCGAGGGCCAGTCCGAGACCATC
  CTTGGCGGCCTGGGGCTCCGGCTGGGCGGCAGCGACTGCAGAGTGAAAATTGATACCAAG
  GCCATTCCACTGTTTGGGAACTCCCTGAAGCCTGACAGTCTCCGGTTCCAGCTGGAGACG
  TCACTGAAGCGGCTGCAGTGTCCCCGAGTGGACCTCTTCTACCTGCATATGCCAGACCAC
  AGCACCCCGGTGGAAGAGACACTGCGTGCCTGCCACCAGCTGCACCAGGAGGGCAAGTTC
  GTGGAGCTTGGCCTCTCCAACTATGCAGCCTGGGAAGTGGCCGAGATCTGTACCCTCTGC
  AAGAGCAACGGCTGGATCCTGCCCACTGTGTACCAGGGCATGTACAATGCCATCACCCGG
  CAGGTGGAAACGGAGCTCTTCCCCTGCCTCAGGCACTTTGGACTGAGGTTCTATGCCTTC
  AACCCTCTGGCTGGGGGCCTGCTGACCGGCAAGTACAAGTATGAGGACAAGGATGGGAAA
  CAGCCTGTGGGCCGCTTCTTTGGGAATACCTGNGCAGAGATGTACAGGAATCGCTACTGG
  AAGGAGCACCACTTTGAGGGCATTGCCCTGGTGGAGAAAGCCCTGCAGNCCGCGTATGGC
  GCCAGCGCCCCCAGCATGACCTCGGCCCCCTNCGGTGGATGTACCACACTCCAGCTGCAG
  GGTGCCACGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003689 unedited
  ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATAAATGACCCAGTCT
  CAGGTATTCTTTTATAGCAACGCAAACAGACTAACACACAGCACCCTGGGAGTTTTATTC
  TTCATTTGGTGGTGACTCTTCTATTAGGTTTTTGTCCAAATACTTCCATCCCTAAGAATT
  TACTGAGGCAGTTCTAAATTAAAGAAAATGTGAGTAACAAAAGATGTTACAGAAGAGCCT
  TGGGCAGCCTGAGAAACGATGGGCCTAGCGGAAGTAGTTGGGACATTCGTGAGCAACCAA
  ATGCCAGGCTTGATTAAAGGCGTCCACGACAGCCGGCTCCAGGGGCCCTTCCTCTGCCGC
  TGCCAAGTTCTGCTCCAGCTGCTCCAGGCTGGACATGCCCAGGATGACCGCGTCCCCGTG
  GGCACCCTGCAGCTGTGAGTGGTGGTACATCCACCGGAGGGTGGCCGAGGTCATGCTGGG
  GGCGCTGGCGCCATACGCGGCCTGCANGGCCTTCTCCACCAGGGCAATGCCCTCAAAGTG
  GTGCTCCTTCCAGTAGCGATCCCTGTACATCTCTGCCCAGGTATTCCCAAAGAACCGGCC
  CCAAGCTGTTTCCCATCCTTGCTCTTATACTTGAACTTGCCGGTCAGCAGGCCCCCAACC
  ACAAGGTTGAAGGCATACAACCTCAGCCCCAAATGCCCTGAGCAGGGGAAAAACCTCCGT
  TCCACCTGCCGGCTGATGGCCTTGATCATGCCCTGGTAACCACTGGGCAAGATCCACCGT
  TGCTTTTGCAAAGGGTCCAATCCCGCGCCTTTCCAACTCCATATTTGGAAAGCCAACTCC
  ACAAACTGCCTCCTGGGGAACTTGTGGCAGGCCCCCCTGGTTTTTCACCGGGTGCTTGGC
  CCGCTTTTGCCGGTAAAAGCCCCCCTCGGAACTGCACCCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003689
• ORF Size: 1080 bp
• Insert Size: 1320
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003689.2, NP_003680.2
• RefSeq Size: 1377
• RefSeq ORF: 1080
• Locus ID: 8574
• Domains: aldo_ket_red
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]