UBE2D1 (NM_003338) Human Untagged Clone

CAT#: SC118046

UBE2D1 (untagged)-Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE2D1
• Synonyms: E2(17)KB1; SFT; UBC4/5; UBCH5; UBCH5A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003338 edited
  GAATTCGGCACGAGGCGCGCTCGGGCGCACACGGAGCAGGGACCGGCGCCCGGAGCGAGC
  CAGGGAGCGGCTAACCGGGGACCCACCGCGCGGAGCCAGCCTAGCTGCCAGCGAGCCCAA
  CCCGCGACGACCCACGCCCCTGAGCCCCGCAGCCGACCCCTGCCGGCCGGTGTCCCCACC
  GCCATCCCTGACCCATGGCGCTGAAGAGGATTCAGAAAGAATTGAGTGATCTACAGCGCG
  ATCCACCTGCTCACTGTTCAGCTGGACCTGTGGGAGATGACTTGTTCCACTGGCAAGCCA
  CTATTATGGGGCCTCCTGATAGCGCATATCAAGGTGGAGTCTTCTTTCTCACTGTACATT
  TTCCGACAGATTATCCTTTTAAACCACCAAAGATTGCTTTCACAACAAAAATTTACCATC
  CAAACATAAACAGTAATGGAAGTATTTGTCTCGATATTCTGAGGTCACAATGGTCACCAG
  CTCTGACTGTATCAAAAGTTTTATTGTCCATATGTTCTCTACTTTGTGATCCTAATCCAG
  ATGACCCCTTAGTACCAGATATTGCACAAATCTATAAATCAGACAAAGAAAAATACAACA
  GACATGCAAGAGAATGGACTCAGAAATATGCAATGTAAAAATCAAAAACATTTTCATATA
  TACCAGAGTACTGTAAAATCTAGGTTTTTTTCAACATTAGCAGTAAATTGAGCACTGTTT
  ACTGTTTCATTGTACCATGAAACCATTTGATTTTTACCCATTTTAAATGTGTTTCTGAAG
  CAAGACAAAACAAACTTCCAAAAATACCCTTAAGACTGTGATGAGAGCATTTATCATTTT
  GTATGCATTGAGAAAGACATTTATTATGGTTTTTAAGATACTTGGACATCTGCATCTTCA
  GCTTACAAGATCTACAATGCAGCTGAAAAGCAACCAAATTATTTTTTGCTGAAACTAGAT
  GTTTTTACATGAGAAATACTGTATGTGTTGTCTAAGATGTCAGTTTTATAAATCTGTATT
  CAGATTTCATTCTTTGTTAGCTCACTTTATAATTTGTATTTTTTTACTGTATAGACTAAA
  TATATTCTATTTACATGTATGTCAACTCATTACTTTTTTCCTGTGAACAGTATTGAAAAA
  CCCCAACGGCTGATAATTAAGTGAATTAACTGTGTCTCCCTTGTCTTAGGATATTCTGTA
  GATTGATTGCAGATTTCTTAAATCTGAAATGATCTTTACACTGTAATTCTCAGCATACTG
  ATTATGGAGAAACACTTGTTTTGATTTTGTTATACTTGACTTAACTTTATTGCAATGTGA
  ATTAATTGCACTGCTAAGTAGGAAGATGTGTAACTTTTATTTGTTGCTATTCACATTTGA
  ATTTTTXXXXXXXXXXXXXXXXXXXXXXCTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003338 unedited
  ATTTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCGCGCTCGGGCG
  CACACGGAGCAGGGACCGGCGCCCGGAGCGAGCCAGGGAGCGGCTAACCGGGGACCCACC
  GCGCGGAGCCAGCCTAGCTGCCAGCGAGCCCAACCCGCGACGACCCACGCCCCTGAGCCC
  CGCAGCCGACCCCTGCCGGCCGGTGTCCCCACCGCCATCCCTGACCCATGGCGCTGAAGA
  GGATTCAGAAAGAATTGAGTGATCTACAGCGCGATCCACCTGCTCACTGTTCAGCTGGAC
  CTGTGGGAGATGACTTGTTCCACTGGCAAGCCACTATTATGGGGCCTCCTGATAGCGCAT
  ATCAAGGTGGAGTCTTCTTTCTCACTGTACATTTTCCGACAGATTATCCTTTTAAACCAC
  CAAAGATTGCTTTCACAACAAAAATTTACCATCCAAACATAAACAGTAATGGAAGTATTT
  GTCTCGATATTCTGAGGTCACAATGGTCACCAGCTCTGACTGTATCAAAAGTTTTATTGT
  CCATATGTTCTCTACTTTGTGATCCTAATCCAGATGACCCCTTAGTACCAGATATTGCAC
  AAATCTATAAATCAGACAAAGAAAAATACAACAGACATGCAAGAGAATGGACTCAGAAAT
  ATGCAATGTAAAAATCAAAAACATTTTCATATATACCAGAGTACTGTAAAATCTAGGTTT
  TTTTCAACATTAGCAGTAAATTGAGCACTGTTTACTGTTTCATTGTACCATGAAACCATT
  TGATTNTTACCCATTNTAAATGTGTTTCTGAAGCAAGACANAACANACTTCCAANAATAC
  CCTTAAGACTGTGATGAGAGCATTTATCATTNTGTATGCATTGAGAAAGAACATTATTAT
  GGTTTNTAAGATACTGGNACATCTGCATCTTCAGCTTACAAGATCTACAATGCAGCTNGA
  AAGCAACCNAATNATNNTTTGCTGAAAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003338 unedited
  GCACGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTTCAAGTTTCAAAAACTTTAAT
  AAAGAAAAAAAAGAAGACACTTCCAAAAATAAATGCCACACAAATGAAAGTTGTTTTTTT
  TTTTGTTTAAAGGGAAGATATTCAAGAAACAAAACCCTTTACTATCAAAATATACTAAAT
  ATTTAAATCTAGGGATGTTGAGTGTTCAAATTCAGGGCAAATGTAGCTTATAATAATATA
  GCTAAGTAAAATTTTTCATGATATGGCTGTTTTAAGACATCATTTTATAGATTTACTTTT
  TAAGCCTATATTTTCTTAAACATCCATTTCACAATTCATTTAATTATTTTACATTCATTT
  ATAAAAACACATATTTTCTAACAATAGGTTATTTTGGGCTTTAATAATAATGAACCATGA
  CAAAATACTCAAGTGATTTAAATGCTTTGCTAATGACTACACCCATCACATATTCTTACA
  TACTTCTACAGCTACTGCAATAATCAGAAGGGCTACAACTGTTCTTAAAAATGACACTCA
  CTCAAGGTTGACAAGCATGCTAAACATTAAAGAGATGTATTTTTCCCCAAGTTAAAACAT
  TAAAACTTTCTAGTTTTCTTTAAAATCTATAAAGATAACCTGCTTATTTAAATCACTTTT
  CGATGGCAACTTATAAAAACAGAGGGAGGCATAATTNTAGAACTTCCTTTGTAACTTCTA
  TAGTAAAAAAAAAAANAAGTTTTTCAAATGGTGATGGCATTAAATCCATTTTAGAAATCC
  TAGATCTTAAATGGTAAGAAATGTNATGTCAATTACATCAAGGTGGGGGGCATTTTAATG
  AAATAATCTAGTGACTGTGCAGGTCTATAAGACCTTNCTTAGNATGGTGATACTGCCTAT
  ACTCATTTAGTTCTTTAACAATTATCCTTTANATTAATCCAGAAAACCCAATTCTCTAAT
  CTCCTTACGCAGGGATCACTTTTNTNCTATGACG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003338
• ORF Size: 444 bp
• Insert Size: 2680
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003338.3, NP_003329.1
• RefSeq Size: 2669
• RefSeq ORF: 444
• Locus ID: 7321
• Domains: UBCc
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.