MAPK11 (NM_002751) Human Untagged Clone

CAT#: SC118466

MAPK11 (untagged)-Human mitogen-activated protein kinase 11 (MAPK11)


  "NM_002751" in other vectors (7)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MAPK11
Synonyms p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_002751 edited
GAATTCGCACGAGGCTCGGGCGCGGGCGCGGGGCGCGGGGCTGGGCCCGGGCGGAGCGGC
GGCTGCTCCGGACATGTCGGGCCCTCGCGCCGGCTTCTACCGGCAGGAGCTGAACAAGAC
CGTGTGGGAGGTGCCGCAGCGGCTGCAGGGGCTGCGCCCGGTGGGCTCCGGCGCCTACGG
CTCCGTCTGTTCGGCCTACGACGCCCGGCTGCGCCAGAAGGTGGCGGTGAAGAAGCTGTC
GCGCCCCTTCCAGTCGCTGATCCACGCGCGCAGAACGTACCGGGAGCTGCGGCTGCTCAA
GCACCTGAAGCACGAGAACGTCATCGGGCTTCTGGACGTCTTCACGCCGGCCACGTCCAT
CGAGGACTTCAGCGAAGTGTACTTGGTGACCACCCTGATGGGCGCCGACCTGAACAACAT
CGTCAAGTGCCAGGCGCTGAGCGACGAGCACGTTCAATTCCTGGTTTACCAGCTGCTGCG
CGGGCTGAAGTACATCCACTCGGCCGGGATCATCCACCGGGACCTGAAGCCCAGCAACGT
GGCTGTGAACGAGGACTGTGAGCTCAGGATCCTGGATTTCGGGCTGGCGCGCCAGGCGGA
CGAGGAGATGACCGGCTATGTGGCCACGCGCTGGTACCGGGCACCTGAGATCATGCTCAA
CTGGATGCATTACAACCAAACAGTGGATATCTGGTCCGTGGGCTGCATCATGGCTGAGCT
GCTCCAGGGCAAGGCCCTCTTCCCGGGAAGCGACTACATTGACCAGCTGAAGCGCATCAT
GGAAGTGGTGGGCACACCCAGCCCTGAGGTTCTGGCAAAAATCTCCTCAGAACACGTGAG
TTGGTGCCCGCCAGCCAGCAGCTCCCTCTCCTGGCTGAGCCCCCAGGCTCTCTGGGGGAG
AGGGTGGTGTGTTAATGCGGGGACCATATGGGGAACATGGGATGTGGTGGGATAGAGCCT
AGGGCAGGTGCCCAATCCCTGCAGGGGAAACAGGAGAAGGGGGAAGACATTCCTGACACC
AGGGACAGTGAGTGCAAAGCCATGACCCCAGCAAGCAGTGCCTGGCCAGGGCAGTGGGGG
TGGGCTGGGGGCCCAGCAAGCAGTGCCTGGCCAGGGCAGTGGGGGTGGGCTGGGGGACCC
CAGCAAGCAGTGCCTGGCCAGGGCAGTGGGGGTGGGCTGGGTGGAGGGAGTGTACTTGGA
CCCAGCTCCTGCAGGCATTAGGGGCCAACTGAGGAGCTAGAACCACCAGATCCTATATGG
AGGGGGTCACTGGTCTGCCTGTGCCCTTGTCCTGGCCTGTTGGAGTGAATGAGTCTGGGG
GCTTGCCAAGAGAAGCCCCAGTTTGGGGCCAGGGAGGCAGAGAGTGAGCAGCCTCCCCAG
GTGTTCTTGTGTGCCCCCAGGCCCGGACATATATCCAGTCCCTGCCCCCCATGCCCCAGA
AGGACCTGAGCAGCATCTTCCGTGGAGCCAACCCCCTGGCCATAGACCTCCTTGGAAGGA
TGCTGGTGCTGGACAGTGACCAGAGGGTCAGTGCAGCTGAGGCACTGGCCCACGCCTACT
TCAGCCAGTACCACGACCCCGAGGATGAGCCAGAGGCCGAGCCATATGATGAGAGCGTTG
AGGCCAAGGAGCGCACGCTGGAGGAGTGGAAGGAGCTCACTTACCAGGAAGTCCTCAGCT
TCAAGCCCCCAGAGCCACCGAAGCCACCTGGCAGCCTGGAGATTGAGCAGTGAGGTGCTG
CCCAGCAGCCCCTGAGAGCCTGTGGAGGGGCTTGGGCCTGCACCCTTCCACAGCTGGCCT
GGTTTCCTCGAGAGGCACCTCCCACACTCCTATGGTCACAGACTTCTGGCCTAGGACCCC
TCGCCTTCAGGAGAATCTACACGCATGTATGCATGCACAAACATGTGTGTACATGTGCTT
GCCATGTGTAGGAGTCTGGGCACAAGTGTCCCTGGGCCTACCTTGGTCCTCCTGTCCTCT
TCTGGCTACTGCACTCTCCACTGGGACCTGACTGTGGGGTCCTAGATGCCAAAGGGGTTC
CCCTGCGGAGTTCCCCTGTCTGTCCCAGGCCGACCCAAGGGAGTGTCAGCCTTGGGCTCT
CTTCTGT
>OriGene 5' read for NM_002751 unedited
AGACCAAGGACCAACAACTTTCNNCCCCCCCGTTCAGATTTGTATACGATCATATAGGCG
GCCGCGNAATTCGCACGAGGCTCGGGCGCGGGCGCGGGGCGCGGGGCTGGGCCCGGGCGG
AGCGGCGGCTGCTCCGGACATGTCGGGCCCTCGCGCCGGCTTCTACCGGCAGGAGCTGAA
CAAGACCGTGTGGGAGGTGCCGCAGCGGCTGCAGGGGCTGCGCCCGGTGGGCTCCGGCGC
CTACGGCTCCGTCTGTTCGGCCTACGACGCCCGGCTGCGCCAGAAGGTGGCGGTGAAGAA
GCTGTCGCGCCCCTTCCAGTCGCTGATCCACGCGCGCAGAACGTACCGGGAGCTGCGGCT
GCTCAAGCACCTGAAGCACGAGAACGTCATCGGGCTTCTGGACGTCTTCACGCCGGCCAC
GTCCATCGAGGACTTCAGCGAAGTGTACTTGGTGACCACCCTGATGGGCGCCGACCTGAA
CAACATCGTCAAGTGCCAGGCGCTGAGCGACGAGCACGTTCAATTCCTGGTTTACCAGCT
GCTGCGCGGGCTGAAGTACATCCACTCGGCCGGGATCATCCACCGGGACCTGAAGCCCAG
CAACGTGGCTGTGAACGAGGACTGTGAGCTCAGGATCCTGGATTTCGGGCTGGCGCGCCA
GGCGGACCAGGAGACGACCGGCTATGTGGCCACGCGCTGGTACCGGGCCCCTGACACATG
CCCCACTGGATGCATTACCACCAACCAGTGGATACTCCCGGCCGCGGGCCTGCACTATGC
GCTGACCTGCTCCAGGGCAAGGGCCCCTCTTCCCCGGGAAGCGACCTACATTGACCCAGC
TAAAACCCATAATGTGAACGGGTGGGCCACACACACACCTTGGGCTTTTCGGAACAAATT
TCCTACAACTCACTTAATTCCCGCGCCGAACAACCCCATATCTACCTCTCTCTGGCCGCA
CCCCCCACGA
>OriGene 3' read for NM_002751 unedited
GCGCTCGAGGACCCCCTTTTACGTGCATCCCTGGTGCAGGCACTTGNCACCCAGGCTTCC
CTGGGCCCCTCGAGGCAAGAGGTCACCCCCTTTCCAGGCAGAGCCACACCCCCAACTCAG
CTCTGGGCAGGGTCCCGTCTCCGAGGTTACTGGATCAGCTCCATCCTGGGACAAGGAAAG
AGGACTGACCCACAGACCAGAGCACCTCAGATCTCCGGCTGCAGGGCCACAACGGTGGGC
AGAGGTAGAGAGCGGGCCAGGGTGCAGGGCAGAAGTGTCCGAGTCCAAGTCCACATCCAG
GTGTGCTGCCTGCCCTAGCGTCCTCAAGGCCAAACCACCCACCCACCCACCCCCAGCCTC
AGGAAGCTGCTGTGGGTCCCACATCCAAGGAGAAAGCCCCTGCCCATGCTCATGTGGTTG
CCCTTTGGCCCACTGGAGCCGCCAGACTCAAACACCCCTCAACGCATCAGGCCCCGTCCG
ATAGGGAACGTAACAGCCCACCCCCCCTATCTTCACCTCCTTGCCAGACCTGGCCGTTCG
CCTTGGGCCCCCACACACTTCCACGCCCCTCATTACATGTCCCCTCGTCCTTCCATCCCC
GTGGCGTGCACCCCCTCTTTCCACCTGTTCTCCCATCTCTCGCCGGTCGCATCTCTTCAT
CCCCAGACATCCCCGACTCATCTTGTCACTTTGGTGGCTCCCCCCTCCCCCACTCCCCCT
GTCACTCTGCTTCGCCTCCCCTCTACTCAACACTCCCATGTTTCCCCCGCCGTTCTTTTT
CCCCCCTCTCTTCCCCTTCTTTCCCCCTCCTCCTATTCCTTCCCCTCACCTCGATTCTTT
TTCCCCCTCCCCGCCCTTTTTGCCCATTTATCCCCCGTACCCAACACACACACCCTTTCT
CCCCCCCTTCTCTTCGTTTCCCTGTTTCCACTTCGCTGCGTCCGCTTTATCCCCCCTT
Restriction Sites ECoRI-NOT     
ACCN NM_002751
Insert Size 1120 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002751.3, NP_002742.3
RefSeq Size 1310 bp
RefSeq ORF 1095 bp
Locus ID 5600
Cytogenetics 22q13.33
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway
Gene Summary 'This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'
Transcript Variant: This variant (1) represents the longer transcript and encodes the protein.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.