SEPTIN5 (NM_002688) Human Untagged Clone

CAT#: SC118516

41522 (untagged)-Human septin 5 (SEPT5), transcript variant 1


  "NM_002688" in other vectors (7)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SEPTIN5
Synonyms CDCREL; CDCREL-1; CDCREL1; H5; HCDCREL-1; PNUTL1; SEPT5
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118516 sequence for NM_002688 edited (data generated by NextGen Sequencing)
ATGAGCACAGGCCTGCGGTACAAGAGCAAGCTGGCGACCCCAGAGGACAAGCAGGACATT
GACAAGCAGTACGTGGGCTTCGCCACACTGCCCAACCAGGTGCACCGCAAGTCGGTGAAG
AAAGGCTTTGACTTCACACTCATGGTGGCTGGTGAGTCAGGCCTGGGGAAGTCCACACTG
GTCCACAGCCTCTTCCTGACAGACTTGTACAAGGACCGGAAGCTGCTCAGTGCTGAGGAG
CGCATCAGCCAGACGGTAGAGATTCTAAAACACACGGTGGACATTGAGGAGAAGGGAGTC
AAGCTGAAGCTCACCATCGTGGACACGCCGGGATTCGGGGACGCTGTCAACAACACCGAG
TGCTGGAAGCCCATCACCGACTATGTGGACCAGCAGTTTGAGCAGTACTTCCGTGATGAG
AGCGGCCTCAACCGAAAGAACATCCAAGACAACCGAGTGCACTGCTGCCTATACTTCATC
TCCCCCTTCGGGCATGGGCTGCGGCCAGTGGATGTGGGTTTCATGAAGGCATTGCATGAG
AAGGTCAACATCGTGCCTCTCATCGCCAAAGCTGACTGTCTTGTCCCCAGTGAGATCCGG
AAGCTGAAGGAGCGGATCCGGGAGGAGATTGACAAGTTTGGGATCCATGTATACCAGTTC
CCTGAGTGTGACTCGGACGAGGATGAGGACTTCAAGCAGCAGGACCGGGAACTGAAGGAG
AGCGCGCCCTTCGCCGTTATAGGCAGCAACACGGTGGTGGAGGCCAAGGGGCAGCGGGTC
CGGGGCCGACTGTACCCCTGGGGGATCGTGGAGGTGGAGAACCAGGCGCATTGCGACTTC
GTGAAGCTGCGCAACATGCTCATCCGCACGCATATGCACGACCTCAAGGACGTGACGTGC
GACGTGCACTACGAGAACTACCGCGCGCACTGCATCCAGCAGATGACCAGCAAACTGACC
CAGGACAGCCGCATGGAGAGCCCCATCCCGATCCTGCCGCTGCCCACCCCGGACGCCGAG
ACTGAGAAGCTTATCAGGATGAAGGATGAGGAACTGAGGCGCATGCAGGAGATGCTGCAG
AGGATGAAGCAGCAGATGCAGGACCAGTGA

Clone variation with respect to NM_002688.5
>OriGene 5' read for NM_002688 unedited
CGGCCGGCGAATTCGCACGAGGGCGCGGAGGGGCCGCTCACCCCGCAGCCCGGCCTCGGC
CTCCGCCGCTTGTCGTCGCGCCCCGCCCGCGAGCCCGCCCCGCACGTCCCCCGCCGGCGG
CCACCATGAGCACAGGCCTGCGGTACAAGAGCAAGCTGGCGACCCCAGAGGACAAGCAGG
ACATTGACAAGCAGTACGTGGGCTTCGCCACACTGCCCAACCAGGTGCACCGCAAGTCGG
TGAAGAAAGGCTTTGACTTCACACTCATGGTGGCTGGTGAGTCAGGCCTGGGGAAGTCCA
CACTGGTCCACAGCCTCTTCCTGACAGACTTGTACAAGGACCGGAAGCTGCTCAGTGCTG
AGGAGCGCATCAGCCAGACGGTAGAGATTCTAAAACACACGGTGGACATTGAGGAGAAGG
GAGTCAAGCTGAAGCTCACCATCGTGGACACGCCGGGATTCGGGGACGCTGTCAACAACA
CCGAGTGCTGGAAGCCCATCACCGACTATGTGGACCAGCAGTTTGAGCAGTACTTCCGTG
ATGAGAGCGGCCTCAACCGAAAGAACATCCAAGACAACCGAGTGCACTGCTGCCTATACT
TCATCTCCCCCTTCGGGCATGGGCTGCGGCCAGTGATGTTGGGTTTCATGAAGGCATTGA
NTGAGAAGGTCAACATCGTGCCTCTCATCGCAAAGCTGACTGTCTTGTCCAAATTGGATC
CNGAAGCTGANGNANCGGATCCNGNAAGNGAATTGAACAGTTTTTGGGATCCATGTTTTA
CCCAGTCCCTTGATTGTGACTTCGACCAAGGATGAGGACTTCAAGCAGCAGACCGGGACT
GGAAGGAAACGCGCCTTTCCCGTATAGCGACACCGGGGGGGGGGAGC
>OriGene 3' read for NM_002688 unedited
NATATCTTGCCCGCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGCGGTCACCAACATTGTTCTCCTG
TCACCAAGACAGGACCCGGGTTTTACAACGGAAAAAAACGGGGCCTTGTGGGGGGGGAAG
GGATCATGCGGGGGGGAACATTGGGGGGCCTAAGCTTAAGATCCCGGCCCACCACAAGGG
GGCTGGGGAAAAAAGGCCTCCAGCGAGGGCCGGGGACCGCCCCCAAAGTTGCCCGGAGGG
GGGTTACCCCCCAAGGCCCCGGGGGCCCTCCAAGTCGGGCCGGGCTTTGGAAAAAGGGGG
TAAACGGTCACAACCCCCCTCCTTGGAACCTTTGGCCTCCTTTTGTTTGGGGGGCTCCCA
TTTGATTTAACCCAACCCTTCCCCCTAGGGGTTTGGGGATAAAGGAAAACTCGGCCCCCC
TCGACAAAAAATGGGGGCTCAACACTCCCTGGGGGACCCCCGGGAACAGGCAAAGGAGGG
CTCCCAAGTCCCTTTTGCACACTGGGGCCGGGAACAAACCCACGATCCTGGGAAACCTTT
TTTGCCTAACTTTGCCTGCCTGCCAAAACAAGGCCTGGGGGTTTTGGGTGGCTGGGACCC
CCCCGGGGGCGGGGGGAAAAGGCAAAGGGAGGCCGGATTTCTTGAAATTCCCGCCCCACT
TTCCCTCCTGTTCCCCCCAGGGCACAAAAGAGGCCACTGGGGGGGGGGGCTTCGGTCCAC
GGCCCCTTGGAACAAACAACATGACCTGGGAGGGGGGGGGGCCCCAAAATAAAATAAGGG
ACCTTGGGGGCTGGTGCCCCCGGTCTCCCGGGGGAGAACAAATCCGCGCTGTGTTCCAAG
GGGCCAAGGGCTCCCCGCAACAACCCGGTTTTCCCCCGCACCACACCGCCCCCCGTTATG
GGTTCTTCTTTGCG
Restriction Sites NotI-NotI     
ACCN NM_002688
Insert Size 2080 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002688.3, NP_002679.2
RefSeq Size 2080 bp
RefSeq ORF 1110 bp
Locus ID 5413
Cytogenetics 22q11.21
Domains GTP_CDC
Protein Families Druggable Genome
Protein Pathways Parkinson's disease
Gene Summary 'This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]'
Transcript Variant: This variant (1) encodes the longer isoform (1).

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