PCDHGC3 (NM_002588) Human Untagged Clone

CAT#: SC118525

PCDHGC3 (untagged)-Human protocadherin gamma subfamily C, 3 (PCDHGC3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGC3
• Synonyms: PC43; PCDH-GAMMA-C3; PCDH2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118525 sequence for NM_002588 edited (data generated by NextGen Sequencing)
  ATGGTCCCAGAGGCCTGGAGGAGCGGACTGGTAAGCACCGGGAGGGTAGTGGGAGTTTTG
  CTTCTGCTTGGTGCCTTGAACAAGGCTTCCACGGTCATTCACTATGAGATCCCGGAGGAA
  AGAGAGAAGGGTTTCGCTGTGGGCAACGTGGTCGCGAACCTTGGTTTGGATCTCGGTAGC
  CTCTCAGCCCGCAGGTTCCGGGTGGTGTCTGGAGCTAGCCGAAGATTCTTTGAGGTGAAC
  CGGGAGACCGGAGAGATGTTTGTGAACGACCGTCTGGATCGAGAGGAGCTGTGTGGGACA
  CTGCCCTCTTGCACTGTAACTCTGGAGTTGGTAGTGGAGAACCCGCTGGAGCTGTTCAGC
  GTGGAAGTGGTGATCCAGGACATCAACGACAACAATCCTGCTTTCCCTACCCAGGAAATG
  AAATTGGAGATTAGCGAGGCCGTGGCTCCGGGGACGCGCTTTCCGCTCGAGAGCGCGCAC
  GATCCCGATGTGGGAAGCAACTCTTTACAAACCTATGAGCTGAGCCGAAATGAATACTTT
  GCGCTTCGCGTGCAGACGCGGGAGGACAGCACCAAGTACGCCGAGCTGGTGTTGGAGCGC
  GCCCTGGACCGAGAACGGGAGCCTAGTCTCCAGTTAGTGCTGACGGCGTTGGACGGAGGG
  ACCCCAGCTCTCTCCGCCAGCCTGCCTATTCACATCAAGGTGCTGGACGCGAATGACAAT
  GCGCCTGTCTTCAACCAGTCCTTGTACCGGGCGCGCGTCCTGGAGGATGCACCCTCCGGC
  ACGCGCGTGGTACAAGTCCTTGCAACGGATCTGGATGAAGGCCCCAACGGTGAAATTATT
  TACTCCTTCGGCAGCCACAACCGCGCCGGCGTGCGGCAACTATTCGCCTTAGACCTTGTA
  ACCGGGATGCTGACAATCAAGGGTCGGCTGGACTTCGAGGACACCAAACTCCATGAGATT
  TACATCCAGGCCAAAGACAAGGGCGCCAATCCCGAAGGAGCACATTGCAAAGTGTTGGTG
  GAGGTTGTGGATGTGAATGACAACGCCCCGGAGATCACAGTCACCTCCGTGTACAGCCCA
  GTACCCGAGGATGCCCCTCTGGGGACTGTCATCGCTTTGCTCAGTGTGACTGACCTGGAT
  GCTGGCGAGAACGGGCTGGTGACCTGCGAAGTTCCACCGGGTCTCCCTTTCAGCCTTACT
  TCTTCCCTCAAGAATTACTTCACTTTGAAAACCAGTGCAGACCTGGATCGGGAGACTGTG
  CCAGAATACAACCTCAGCATCACCGCCCGAGACGCCGGAACCCCTTCCCTCTCAGCCCTT
  ACAATAGTGCGTGTTCAAGTGTCCGACATCAATGACAACCCTCCACAATCTTCTCAATCT
  TCCTACGACGTTTACATTGAAGAAAACAACCTCCCCGGGGCTCCAATACTAAACCTAAGT
  GTCTGGGACCCCGACGCCCCGCAGAATGCTCGGCTTTCTTTCTTTCTCTTGGAGCAAGGA
  GCTGAAACCGGGCTAGTGGGTCGCTATTTCACAATAAATCGTGACAATGGCATAGTGTCA
  TCCTTAGTGCCCCTAGACTATGAGGATCGGCGGGAATTTGAATTAACAGCTCATATCAGC
  GATGGGGGCACCCCGGTCCTAGCCACCAACATCAGCGTGAACATATTTGTCACTGATCGC
  AATGACAATGCCCCCCAGGTCCTATATCCTCGGCCAGGTGGGAGCTCGGTGGAGATGCTG
  CCTCGAGGTACCTCAGCTGGCCACCTAGTGTCACGGGTGGTAGGCTGGGACGCGGATGCA
  GGGCACAATGCCTGGCTCTCCTACAGTCTCTTGGGATCCCCTAACCAGAGCCTTTTTGCC
  ATAGGGCTGCACACTGGTCAAATCAGTACTGCCCGTCCAGTCCAAGACACAGATTCACCC
  AGGCAGACTCTCACGGTCTTGATCAAAGACAATGGGGAGCCTTCGCTCTCCACCACTGCT
  ACCCTCACTGTGTCAGTAACCGAGGACTCTCCTGAAGCCCGAGCCGAGTTCCCCTCTGGC
  TCTGCCCCCCGGGAGCAGAAAAAAAATCTCACCTTTTATCTACTTCTTTCTCTAATCCTG
  GTTTCTGTGGGGTTCGTGGTCACAGTGTTCGGAGTAATCATATTCAAAGTTTACAAGTGG
  AAGCAGTCTAGAGACCTATACCGAGCCCCGGTGAGCTCACTGTACCGAACACCAGGGCCC
  TCCTTGCACGCGGACGCCGTGCGGGGAGGCCTGATGTCGCCGCACCTTTACCATCAGGTG
  TATCTCACCACGGACTCCCGCCGCAGCGACCCGCTGCTGAAGAAACCTGGTGCAGCCAGT
  CCACTGGCCAGCCGCCAGAACACGCTGCGGAGCTGTGATCCGGTGTTCTATAGGCAGGTG
  TTGGGTGCAGAGAGCGCCCCTCCCGGACAGCAAGCCCCGCCCAACACGGACTGGCGTTTC
  TCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGG
  CCCAACAACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAA
  GCTGCTGATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGC
  TACGGACCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCA
  GGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGT
  GGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
  
  Clone variation with respect to NM_002588.2
  582 g=>c;2115 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002588 unedited
  TGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGCGGACTCGGCGCCCAG
  CGCCCAAGCGCTAACCCGCTGAAAGTTTCTCAGCGAAATCTCAGGGACGATCTGGACCCC
  GCTGAGAGGAACTGCTTTTGAGTGAGATGGTCCCAGAGGCCTGGAGGAGCGGACTGGTAA
  GCACCGGGAGGGTAGTGGGAGTTTTGCTTCTGCTTGGTGCCTTGAACAAGGCTTCCACGG
  TCATTCACTATGAGATCCCGGAGGAAAGAGAGAAGGGTTTCGCTGTGGGCAACGTGGTCG
  CGAACCTTGGTTTGGATCTCGGTAGCCTCTCAGCCCGCAGGTTCCGGGTGGTGTCTGGAG
  CTAGCCGAAGATTCTTTGAGGTGAACCGGGAGACCGGAGAGATGTTTGTGAACGACCGTC
  TGGATCGAGAGGAGCTGTGTGGGACACTGCCCTCTTGCACTGTAACTCTGGAGTTGGTAG
  TGGAGAACCCGCTGGAGCTGTTCAGCGTGGAAGTGGTGATCCAGGACATCAACGACAACA
  ATCCTGCTTTCCCTACCCAGGAAATGAAATTGGAGATTAGCGAGGCCGTGGCTCCGGGGA
  CGCGCTTTCCGCTCGAGAGCGCGCACGATCCCGATGTGGGAAGCAACTCTTTACAAACCT
  ATGAGCTGAGCCGAAATGAATACTTTGCGCTTCGCGTGCAGACGCGGGAGGACAGCACCA
  AGTACGCCGAGCTGGTGTTGGAGCGCGCCCTGNNACCGAGACGGGAGCCTAGTCTCCATT
  AGTGCTGACNGCGTTGGNACGGAGGGACCCAGCTCTCTTCGNCAGCCTGCCTATTACATC
  ANGGTGCTGGACGCGAATGACATGCGCCTGTCTTCACCAGTCTTGNACNGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002588 unedited
  NCCCTTTTGACTATGGACCGGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTT
  TTTTTTTTTCAAAAAAACGTTTTATTATTTTTTTGTCGAAAAAAAAAAGCCTATAAATAT
  TAGAGTATAAAACTTGCGTGAGACACAGGAAGAGGGTGGGGTGGGAGCTACGTGACTATG
  CGAAAAGAAGCGCTTATAGGAAAAGTCAGTACGGGGGAGGGGGTCGCCTTAGCGCGTGGA
  CACAGCACAAAACACAACACGGGCCGCCGCGGGCAGATCAAGGACAGACGGTTGCGCGGA
  GCCCGCCGCCCGTTGCCCACCCGCCATCACGTAAAAGCACACCGCACTACACTACTGGCT
  ATTCTACACCAGCCGAAAGAGGGAGGGGGCGCTACACTACTGTAAGGGCAGGTCTGGGGT
  TCTCTGGCAGCCCCGCTGGATGGCCGGGGACCCAGGGGCAAAAGGGGGTGGGAGAAAAAG
  GTCTATGCACAAGGAGGCACTGGGGAACTTTAACCAGGCTATGGCCACTAGGGGGCGCAC
  TGGGGACCTGGGCAGTGGCCTTCACGGAAGAGAAACGGCACCTGGCAAGGTGAAGGACTG
  AGGCTTCAGGAGGGCAGGGGCCCTGTTGAAAAAGCCCCATCCTGGGCTGAGACCTTCTGT
  TCATTTGGCCCCTGCCCTAGCTCCCTGCCTCCCCACCCCAGGGACTAAGAATGGCCTGGC
  TGGCCCACCCTTCCTGCTGGGGCTCCGCTGACCCTTTCACCAGTGGCACCTTTGGAGTAC
  CCANACCCACAGAGGCCCCTTTGACCTTTAAAGGGGACCCGGCCTAAACCTGGTTCGAGC
  TTCCTTGAACTGAAAGGCCAGNTTAATCCTGGGGCCTGTAAGCCTACCCAAACTGGCTGC
  CTGGCTTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002588
• Insert Size: 4640 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002588.2, NP_002579.2
• RefSeq Size: 4726 bp
• RefSeq ORF: 2805 bp
• Locus ID: 5098
• Cytogenetics: 5q31.3
• Domains: CA
• Protein Families: Transmembrane
• Gene Summary: 'This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1).