MVD (NM_002461) Human Untagged Clone

CAT#: SC118602

MVD (untagged)-Human mevalonate (diphospho) decarboxylase (MVD)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MVD
• Synonyms: FP17780; MDDase; MPD; POROK7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002461 edited
  GCGAATTCGGCACGAGGACTGCGCGGTGGGACCATGGCCTCGGAGAAGCCGCTGGCGGCA
  GTCACTTGTACAGCGCCGGTCAACATCGCGGTCATCAAGTACTGGGGCAAGCGCGATGAA
  GAGCTGGTTCTGCCCATCAACTCCTCCCTGAGCGTCACTCTGCACCAGGACCAGTTAAAA
  ACCACCACAACAGCCGTCATCAGCAAGGACTTCACCGAGGACCGGATTTGGCTGAATGGC
  CGGGAGGAGGATGTGGGGCAGCCGAGGCTGCAGGCCTGCCTGCGGGAGATCCGCTGCCTG
  GCCCGGAAGCGGAGGAACTCACGGGATGGGGACCCGCTGCCCTCCAGCCTCAGCTGCAAG
  GTGCACGTGGCATCGGTGAACAACTTCCCCACGGCTGCGGGCCTGGCCTCCTCAGCGGCG
  GGCTATGCCTGCCTAGCCTACACCCTGGCCCGTGTCTACGGCGTGGAGAGTGACCTCTCA
  GAAGTGGCTCGCCGGGGCTCAGGCAGCGCCTGCCGGAGCCTGTATGGGGGCTTTGTGGAG
  TGGCAGATGGGAGAGCAGGCCGACGGGAAGGACAGCATCGCTCGGCAAGTGGCCCCCGAG
  TCACACTGGCCTGAACTCCGCGTGCTCATCCTTGTGGTGAGCGCTGAGAAGAAGCTGACA
  GGCAGTACCGTGGGCATGCGGGCCAGTGTGGAGACCAGCCCCCTGCTTCGGTTCCGGGCC
  GAGTCCGTGGTGCCCGCGCGCATGGCGGAGATGGCCCGCTGCATCCGGGAGCGAGACTTC
  CCCAGCTTCGCCCAGCTGACCATGAAGGACAGCAACCAGTTCCACGCCACCTGCCTCGAC
  ACCTTCCCGCCCATCTCTTACCTCAATGCCATCTCCTGGCGCATCATCCACCTGGTGCAC
  CGCTTCAACGCCCACCACGGGGACACCAAGGTGGCGTACACCTTTGACGCGGGCCCCAAT
  GCCGTGATCTTCACCCTGGACGACACTGTGGCTGAGTTTGTGGCTGCTGTGTGGCACGGC
  TTTCCCCCAGGCTCGAATGGAGACACGTTTCTGAAGGGGCTGCAGGTGAGGCCGGCCCCT
  CTCTCAGCTGAGCTTCAGGCTGCGCTGGCCATGGAGCCGACCCCCGGTGGGGTCAAGTAC
  ATCATTGTCACTCAGGTGGGGCCAGGGCCTCAAATCCTGGATGACCCCTGCGCCCACCTC
  CTGGGTCCTGACGGCCTGCCGAAGCCAGCTGCCTGACTGCCTCAGCAGGGACCGCATGCC
  GCTTGGAGAAGGGGTGGCCTCGCCGGAGCTAGGGAGCGGATGTGGTGGGCTGGCCGGACT
  CCTGGGACATGTGGGTGGTGGCTTGACCCCGGGCCCATGGGCAGCTTGCTGTGGGGCAGT
  GCAGGGAGTCCTGCGGCCGCCCAGGTGTCAGGAGAGGTCCCCGCCGAGTGCTTCAGCTGC
  CCTAAGCTGCACCAGCGCTTTGCC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002461 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGACTGCGCGGTGGGACCA
  TGGCCTCGGAGAAGCCGCTGGCGGCAGTCACTTGTACAGCGCCGGTCAACATCGCGGTCA
  TCAAGTACTGGGGCAAGCGCGATGAAGAGCTGGTTCTGCCCATCAACTCCTCCCTGAGCG
  TCACTCTGCACCAGGACCAGTTAAAAACCACCACAACAGCCGTCATCAGCAAGGACTTCA
  CCGAGGACCGGATTTGGCTGAATGGCCGGGAGGAGGATGTGGGGCAGCCGAGGCTGCAGG
  CCTGCCTGCGGGAGATCCGCTGCCTGGCCCGGAAGCGGAGGAACTCACGGGATGGGGACC
  CGCTGCCCTCCAGCCTCAGCTGCAAGGTGCACGTGGCATCGGTGAACAACTTCCCCACGG
  CTGCGGGCCTGGCCTCCTCAGCGGCGGGCTATGCCTGCCTAGCCTACACCCTGGCCCGTG
  TCTACGGCGTGGAGAGTGACCTCTCAGAAGTGGCTCGCCGGGGCTCAGGCAGCGCCTGCC
  GGAGCCTGTATGGNGGCTTTGTGGAGTGGCAGATGGGAGAGCAGGCCGACGGGAAGGACA
  GCATCGCTCGGCAAGTGGCCCCCGAGTCACACTGGCCTGAACTCCGCGTGCTCATCCTTG
  TGGTGAGCGCTGAGAAGAAGCTGACAGGCAGTACCGTGGGCATGCGGNCCAGTGTGGAGA
  CCAGCCCCTGCTTCNGTTCCGGNCCGAGTCCGTGGTGCCCGCGCGCATGGCNGAGATGGC
  CCGCTGCATCCGGGAGCGAGACTTNCCCAGCTTCGNCCAGCTGACCATGAAGACANNGCA
  CCAGTCCACGCCNACTGGCTNGACACCTTNCCCGCCATNTCTTACCTCATGCCATCTCTG
  GCGCATCATCCACCTGGTGCACCGCTCAACGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002461 unedited
  CGCGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGGCAGCAATGCTGGTTTAT
  TCCCCATGGCCACCGGGGCCGCACTGGTGCCCACTCCTGCCACCATTCCAGCCACACCCA
  GGCCGTGGGCAGCCACCCTCCGAGACACCTGGGCCGGGGGCAGGGTCTCAGCAGAAGCGC
  CGTGGGCAGCCACCATCCGAGGCACTTGGTGGTTTCCTGAGGCCCAAGGAGGCTGCTCCC
  AGCACAGTGACCCCTTCCCTGGTCCGCTGGAGGGACCACCTCCCCACTGAGCTACTTTCT
  CAGAGAACTGGGCATAGCCAGAGCTGGGGTGAGAAAGCCCTTCACCCCTGCTGCACCGAG
  GCTCTGGCAGTTCTCATACCCCCTCCCCATCCCATCTTGGCAAAGCGCTGGCGCAACTTA
  AGGCAGCTGAAGCACTCGGCGGGGACCTTTCCTGACACCTGGGCGGACGCAGGACTCCCT
  GCACTGCCCCACAGCAAGCTGCCCATGGGCCCGGGGACAAGCCACCACCCACATGTACCC
  AGAGATCGGACAGCCCACCACATACGGTCCCTACATTCGGGGAAGCCACCACTTTTTACA
  AACGGACTGTCGGCCCCTCGCTGAAGCCAATCACGACACCTGGATTCGGAAAGCCCGCTT
  GGACCCAGAAGGTGGGGCCCTGGGGTCCTCACACAAATTGATGGCCCTGCCCACCCCTGG
  ATGACATGGATGAACTTTGACCACCCCGGGGGAAGATTACTTGGACCCCCCCACCCCGAA
  ACCTCAATTTGAAAAAGGGAACGATACCAACCGCCAGCCCCTAAAAAAACCGCGATTGTT
  TCCCAACCGGGGGAAACTCATCTCCCACATGTCACCCATAACTCTCCCGTCAGGTACTAT
  TGGGGATACATATAAGACATTGGAGACCCACCACCAAGGG
  
• Restriction Sites: EcoRI-XbaI
• ACCN: NM_002461
• Insert Size: 1910 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002461.1, NP_002452.1
• RefSeq Size: 1812 bp
• RefSeq ORF: 1203 bp
• Locus ID: 4597
• Cytogenetics: 16q24.2
• Domains: GHMP_kinases
• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis
• Gene Summary: 'The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008]'