KCNK3 (NM_002246) Human Untagged Clone

CAT#: SC118713

KCNK3 (untagged)-Human potassium channel, subfamily K, member 3 (KCNK3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNK3
• Synonyms: K2p3.1; OAT1; PPH4; TASK; TASK-1; TBAK1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002246 edited
  GGCGAGCGCAGCCATGCCCCAGGCCGCCTCCGGGGCAGCAGCAGCGGCGGCCGGGGCCGA
  GGCGCGGGCCGGGGGCGCCGGGGGGCCGGCGGCGGCCCGGGCGGGACGATGAAGCGGCAG
  AACGTGCGCACGCTGGCGCTCATCGTGTGCACCTTCACCTACCTGCTGGTGGGCGCCGCG
  GTCTTCGACGCGCTGGAGTCGGAGCCCGAGCTGATCGAGCGGCAGCGGCTGGAGCTGCGG
  CAGCAGGAGCTGCGGGCGCGCTACAACCTCAGCCAGGGCGGCTACGAGGAGCTGGAGCGC
  GTCGTGCTGCGCCTCAAGCCGCACAAGGCCGGCGTGCAGTGGCGCTTCGCCGGCTCCTTC
  TACTTCGCCATCACCGTCATCACCACCATCGGCTACGGGCACGCGGCACCCAGCACGGAT
  GGCGGCAAGGTGTTCTGCATGTTCTACGCGCTGCTGGGCATCCCGCTCACGCTCGTCATG
  TTCCAGAGCCTGGGCGAGCGCATCAACACCTTGGTGAGGTACCTGCTGCACCGCGCCAAG
  AAGGGGCTGGGCATGCGGCGCGCCGACGTGTCCATGGCCAACATGGTGCTCATCGGCTTC
  TTCTCGTGCATCAGCACGCTGTGCATCGGCGCCGCCGCCTTCTCCCACTACGAGCACTGG
  ACCTTCTTCCAGGCCTACTACTACTGCTTCATCACCCTCACCACCATCGGCTTCGGCGAC
  TACGTGGCGCTGCAGAAGGACCAGGCCCTGCAGACGCAGCCGCAGTACGTGGCCTTCAGC
  TTCGTCTACATCCTTACGGGCCTCACGGTCATCGGCGCCTTCCTCAACCTCGTGGTGCTG
  CGCTTCATGACCATGAACGCCGAGGACGAGAAGCGCGACGCCGAGCACCGCGCGCTGCTC
  ACGCGCAACGGGCAGGCGGGCGGCGGCGGAGGGGGTGGCAGCGCGCACACTACGGACACC
  GCCTCATCCACGGCGGCAGCGGGCGGCGGCGGCTTCCGCAACGTCTACGCGGAGGTGCTG
  CACTTCCAGTCCATGTGCTCGTGCCTGTGGTACAAGAGCCGCGAGAAGCTGCAGTACTCC
  ATCCCCATGATCATCCCGCGGGACCTCTCCACGTCCGACACGTGCGTGGAGCAGAGCCAC
  TCGTCGCCGGGAGGGGGCGGCCGCTACAGCGACACGCCCTCGCGACGCTGCCTGTGCAGC
  GGGGCGCCACGCTCCGCCATCAGCTCGGTGTCCACGGGTCTGCACAGCCTGTCCACCTTC
  CGCGGCCTCATGAAGCGCAGGAGCTCCGTGTGACTGCCCCGAGGGACCTGGAGCACCTGG
  GGGCGCGGGCGGGGGACCCCTGCTGGGAGGCCAGGAGACTGCCCCTGCTGCCTTCTGCCC
  AGTGGGACCCCGCACAACATCCCTCACCACTCTCCCCCAGCACCCCCATCTCCGACTGTG
  CCTGCTTGCACCAGCCGGCA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002246 unedited
  TCAGCATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCGGGTGCCCGG
  CGCGGAGAGCGGCGAGCGCAGCCATGCCCCAGGCCGCCTCCGGGGCAGCAGCAGCGGCGG
  CCGGGGCCGAGGCGCGGGCCGGGGGCGCCGGGGGGCCGGCGGCGGCCCGGGCGGGACGAT
  GAAGCGGCAGAACGTGCGCACGCTGGCGCTCATCGTGTGCACCTTCACCTACCTGCTGGT
  GGGCGCCGCGGTCTTCGACGCGCTGGAGTCGGAGCCCGAGCTGATCGAGCGGCAGCGGCT
  GGAGCTGCGGCAGCAGGAGCTGCGGGCGCGCTACAACCTCAGCCAGGGCGGCTACGAGGA
  GCTGGAGCGCGTCGTGCTGCGCCTCAAGCCGCACAAGGCCGGCGTGCAGTGGCGCTTCGC
  CGGCTCCTTCTACTTCGCCATCACCGTCATCACCACCATCGGCTACGGGCACGCGGCACC
  CAGCACGGATGGCGGCAAGGTGTTCTGCATGTTCTACGCGCTGCTGGGCATCCCGCTCAC
  GCTCGTCATGTTCCAGAGCCTGGGCGAGCGCATCAACACCTTGGTGAGGTACCTGCTGCA
  CCGCGCCAAGAAGGGGCTGGGCATGCGGCGCGCCGACGTGTCCATGGCCAACATGGTGCT
  CATCGGCTTCTTCTCGTGCATCAGCACGCTGTGCATCGGCGCCGCCGCCTTCTCCCACTA
  CGAGCACTGGACCTTCTTNCAGGCCTACTACTACTGCTTCATCACCCTCACCACCATCGG
  CTTCNGCGACTACGTGGCGCTGCAGAAGGACCAGGCCCTGCAGACGCAGCCGCAGTACGT
  GGCCTTCAGCTTCGTCTACTCCTTACGGGCCTCACGGTCATCGGCGCCTTNNCTCACCTC
  GTGGTGCTGCGGCTTATGACCATGAACGCCGAGGACGAAAGCGCGACGCCCAGCACGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002246 unedited
  GAGTTCTTGCCCAGCCACCCAGGCTGGNATACAGTGGTGCAANTCAGGGCTCACTACAGC
  CTCGACCTCCCAGGCTCAAACAATCCTCCCACCTCAGCCTCCCAAGTCGCTGGGACTCCC
  AGGCACGTGCCACCACACCTGGTTAATTTTTTATTTTTTGTAGAGATGGGGTCTCACTAT
  GTCACCTAGGCTGGTCTCGAATTCCTGGGCTCAAGCAATCCTCCAACCTCAGCCTCCAAA
  AGTGTTGGGAATACAGGTGTGAGCCACTGCACCCAGCCCCCACCCCTTTGCCTTTTGCTC
  TCTGGTCACTTCACCTGTCCAGGCCTCAGTATTCTCATCTGTAAAATGGGAGTGAGAACT
  CCTGCCCTGATGACCTAAGTAGGGTTTTGTGAGACTCAAAGGAATCAGTGGCCAGCATAG
  AGTTTTCAGAGGCTAAAAATCACTCGACAAATTTAAGAGTGGGTAATTATCAGCAATTAT
  GGTGAGTCTGAAGTCTTCTGTTCCAGATTCTAAGGGCAGTGTCTGGAAGGCTGAAGTCCT
  ACCTGCTATGAGAATGTGGCTGGAGGCCAGTTAGCTTGAACCTCCAGTGCGACCATTCTG
  CAGACTGACAGGCCGCTGCCTCCTGCCTCCCAGCTCGCCCCTCCTGCTGCCTGCCTGTCC
  CTCCTTCTTTCTGTCCTGCTTTCTGGGACCAGCTTTAAGGACTGCTGGGTTTCCACTTTC
  TCCATAACTGCAAAGCCATGCAAAAACACACGAAGGGAAGTTTGGGAGACACAGCTGGGG
  ATGAGGAAGGGGGAGTGGGGCTGATTAGGGGTGACCTGGAACATAACACCCTGGCTTTTG
  GAACCCAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002246
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002246.1, NP_002237.1
• RefSeq Size: 2590 bp
• RefSeq ORF: 1185 bp
• Locus ID: 3777
• Cytogenetics: 2p23.3
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: 'This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]'