KPNA3 (NM_002267) Human Untagged Clone

CAT#: SC118722

KPNA3 (untagged)-Human karyopherin alpha 3 (importin alpha 4) (KPNA3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KPNA3
• Synonyms: hSRP1; IPOA4; SRP1; SRP1gamma; SRP4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118722 sequence for NM_002267 edited (data generated by NextGen Sequencing)
  ATGGCCGAGAACCCCAGCTTGGAGAACCACCGCATCAAGAGCTTCAAGAACAAGGGCCGC
  GATGTGGAAACAATGCGAAGACATAGAAATGAAGTGACAGTGGAACTGCGGAAGAACAAA
  AGAGATGAACACTTATTGAAAAAGAGAAATGTTCCCCAAGAAGAAAGTCTAGAAGATTCA
  GATGTTGATGCTGATTTTAAAGCACAAAATGTAACCCTAGAAGCTATATTGCAGAATGCC
  ACAAGTGATAACCCAGTGGTCCAATTGAGTGCTGTCCAGGCAGCAAGAAAACTGTTATCC
  AGTGACAGAAATCCACCGATTGATGACTTAATAAAATCTGGGATTTTACCAATTCTAGTC
  AAATGTCTAGAAAGGGATGATAATCCTTCATTACAGTTTGAAGCTGCTTGGGCATTAACT
  AACATAGCATCAGGAACTTCTGCACAGACTCAAGCTGTTGTGCAGTCTAATGCAGTACCT
  CTTTTTCTGAGACTTCTTCGTTCACCACATCAGAATGTTTGTGAACAAGCAGTATGGGCT
  TTGGGAAACATTATAGGTGATGGTCCTCAATGTAGAGATTATGTCATATCACTGGGAGTT
  GTCAAACCTCTTCTGTCCTTCATCAGTCCCTCCATCCCCATCACCTTCCTTCGGAACGTC
  ATATGGGTCATTGTCAATCTCTGCAGGAATAAGGATCCCCCACCGCCTATGGAGACAGTT
  CAGGAGATTTTGCCAGCTTTATGTGTCCTCATATACCATACAGATATAAACATTCTTGTA
  GACACTGTTTGGGCTCTGTCATACTTGACAGATGGAGGTAATGAACAGATACAGATGGTT
  ATTGATTCAGGAGTTGTGCCCTTTCTTGTGCCCCTTCTGAGCCATCAGGAAGTCAAAGTT
  CAAACAGCAGCCCTCAGAGCAGTTGGCAACATAGTGACTGGCACCGACGAGCAGACCCAG
  GTTGTTCTCAATTGTGATGTCCTGTCACACTTCCCAAATCTCTTATCACACCCAAAAGAG
  AAGATAAATAAGGAAGCAGTGTGGTTCCTTTCCAACATAACAGCAGGCAACCAGCAACAA
  GTTCAAGCTGTAATAGATGCTGGATTAATTCCTATGATAATTCATCAGCTTGCTAAGGGG
  GACTTTGGAACACAAAAAGAAGCTGCTTGGGCAATCAGCAACTTAACAATAAGTGGCAGA
  AAAGATCAGGTTGAGTACCTTGTACAGCAGAATGTAATACCACCGTTCTGTAATTTACTG
  TCAGTGAAAGATTCTCAAGTGGTTCAGGTGGTTCTAGATGGTCTAAAAAACATTCTGATA
  ATGGCCGGTGATGAAGCAAGCACAATAGCTGAAATAATAGAGGAATGTGGAGGTTTGGAG
  AAAATTGAAGTTTTACAGCAACATGAAAATGAAGACATATATAAATTAGCATTTGAAATC
  ATAGATCAGTATTTCTCTGGTGATGATATTGATGAAGATCCCTGCCTCATTCCTGAAGCA
  ACACAAGGAGGTACCTACAATTTTGATCCAACAGCCAACCTTCAAACAAAAGAATTTAAT
  TTTTAA
  
  Clone variation with respect to NM_002267.3
  662 c=>t;702 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002267 unedited
  GTCGGATTTGTATACGACTCACTATAGGCGGCCCGCGAATCGGCACGAGGGGCCCCACCC
  GGCCCGGCAGTCGGCCCGCGCCTCCCCCGGCGCTACTGCCACCTCGCGCTCGGAGGCGTC
  ACAGAACGTGCTCTTCTCTCCCCCTCCCCCCTCCCGCTCTCCCCCTCCTCCCCCTCCCGC
  TCCAAGATTCGCCGCCGCCGCCGCCGCAGCCGCAGGAGTAGCCGCCGCCGGAGCCGCGCG
  CAGCCATGGCCGAGAACCCCAGCTTGGAGAACCACCGCATCAAGAGCTTCAAGAACAAGG
  GCCGCGATGTGGAAACAATGCGAAGACATAGAAATGAAGTGACAGTGGAACTGCGGAAGA
  ACAAAAGAGATGAACACTTATTGAAAAAGAGAAATGTTCCCCAAGAAGAAAGTCTAGAAG
  ATTCAGATGTTGATGCTGATTTTAAAGCACAAAATGTAACCCTAGAAGCTATATTGCAGA
  ATGCCACAAGTGATAACCCAGTGGTCCAATTGAGTGCTGTCCAGGCAGCAAGAAAACTGT
  TATCCAGTGACAGAAATCCACCGATTGATGACTTAATAAAATCTGGGATTTTACCAATTC
  TAGTCAAATGTCTAGAGAGGGATGATAATCCTTCATTACAGTTTGAAGCTGCTTGGGCAT
  TAACTAACATAGCATCAGGAACTTCTGCACAGACTCAAGCTGTTGTGCAGTCTAATGCAG
  TACCTCTTTTTCTGAGACTTCTTCGNTCACCACATCAGAATGTTTGTGAACAAGCAGTAT
  GGGCTTTGGGAAACATTATAGGGTGATGGTCCTCAATGTAGAGATTATGTCATATCACTG
  GGGAGTTGTCAAACCTCCTTCTGTCCTTCATCAGTNCCTCCATCCCCATCACCCTTCTTT
  GGAACGTCATAGGGGTCATTGGCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002267 unedited
  ATGGCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAACTTATCTGTT
  TATTCAATAACCAAGTTTCTTGTTTTTAAGTTACTTTTTTTGTGTCAGTTCCACCAATGA
  AAATCATTTGGCTTGTACTTTAAAATCTATTCTTCCACATAAAGAATATGAAAATATGTT
  TGTGGAGGACAATGATGGAGGCTCAGATCACATTGCACCTCTTTAGTCTTCCAACTTGTA
  TATGCATCATACCAAAGTGTCTTGATCCACAGCGCACCATTTTCCAAAGGAGTATCAGTG
  GGCAGCTGACATGTCACCACTATGGAATATTTATTCTAAACTGGAGACTGCAGTTGTCAG
  CCTGTGGCACCAGGGAACAGGGAAAAATAGGGTAGTTGAGATTGTTAAGGAGAGTTCTAA
  AACAGTTTAGGAAATCATGCATATGCATTTACAGTCCATGTGATAGTGACTTTTGGCAAC
  TGCAAAGTGACTGAGACATGGCTTGCTTTANAAGCATCAAAACAAAGAGGCATGTGTGTT
  TTGGAGCCTTTTGTTGCTGTTGTTCTTATCATTTGGTAGCCATCTGGTGGTGCTTCATAT
  TGAATGTGGGAAAGATGCTGCACTCAACTGAATTTAAAAATTAAATTCTTTTGTTTGAAG
  GTTGGCTGTTGGATCAAAATTGTANGTACCTCCTTGTGTTGCTTCAGAAATGAGCAGGNA
  TCTTCATCAATATCATCACCAGAGAAATACTGATCTATGATTTCAAATGCTAANTTATAT
  ATGNCTTCATTTTTCATGTGCTGNAAAACTTCATTTTCTCCAAACTNCACATTNCTCTAT
  TATTTCAGCTATTGNGCTTGCTTCATCACCNGCCATTATCAGAATGNTTNTTAGACATCT
  AGAACCACTGAACCACTGAGATACTTACTGACGTAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002267
• Insert Size: 2430 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002267.2, NP_002258.2
• RefSeq Size: 4471 bp
• RefSeq ORF: 1566 bp
• Locus ID: 3839
• Cytogenetics: 13q14.2
• Domains: Armadillo_seg, IBB
• Gene Summary: 'The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. [provided by RefSeq, Jan 2009]'