FES (NM_002005) Human Untagged Clone

CAT#: SC118883

FES (untagged)-Human feline sarcoma oncogene (FES), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FES
• Synonyms: FPS
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118883 sequence for NM_002005 edited (data generated by NextGen Sequencing)
  ATGGGCTTCTCTTCCGAGCTGTGCAGCCCCCAGGGCCACGGGGTCCTGCAGCAAATGCAG
  GAGGCCGAGCTTCGTCTACTGGAGGGCATGAGAAAGTGGATGGCCCAGCGGGTCAAGAGT
  GACAGGGAGTATGCAGGACTGCTTCACCACATGTCCCTGCAGGACAGTGGGGGCCAGAGC
  CGGGCCATCAGCCCTGACAGCCCCATCAGTCAGTCCTGGGCTGAGATCACCAGCCAAACT
  GAGGGCCTGAGCCGCTTGCTGCGGCAGCACGCAGAGGATCTGAACTCAGGGCCCCTGAGC
  AAGCTGAGCCTGCTCATCCGGGAACGGCAGCAGCTTCGCAAGACCTACAGCGAGCAGTGG
  CAGCAGCTGCAGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGCTGAAGAGC
  CAGTACCGAGCTCTGGCACGGGACAGTGCCCAAGCCAAGCGCAAGTACCAGGAGGCCAGC
  AAAGACAAGGACCGTGACAAGGCTAAGGACAAGTATGTGCGCAGCCTGTGGAAGCTCTTT
  GCTCACCACAACCGCTATGTGCTGGGCGTGCGGGCTGCGCAGCTACACCACCAGCACCAC
  CACCAGCTCCTGCTGCCCGGCCTGCTGCGGTCACTGCAGGACCTGCACGAGGAGATGGCT
  TGCATCCTGAAGGAGATCCTGCAGGAATACCTGGAGATTAGCAGCCTGGTGCAGGATGAG
  GTGGTGGCCATTCACCGGGAGATGGCTGCAGCTGCTGCCCGCATCCAGCCTGAGGCTGAG
  TACCAAGGCTTCCTGCGACAGTATGGGTCCGCACCTGACGTCCCACCCTGTGTCACGTTC
  GATGAGTCACTGCTTGAGGAGGGTGAACCGCTGGAGCCTGGGGAGCTCCAGCTGAACGAG
  CTGACTGTGGAGAGCGTGCAGCACACGCTGACCTCAGTGACAGATGAGCTGGCTGTGGCC
  ACCGAGATGGTGTTCAGGCGGCAGGAGATGGTTACGCAGCTGCAACAGGAGCTCCGGAAT
  GAAGAGGAGAACACCCACCCCCGGGAGCGGGTGCAGCTGCTGGGCAAGAGGCAAGTGCTG
  CAAGAAGCACTGCAGGGGCTGCAGGTAGCGCTGTGCAGCCAGGCCAAGCTGCAGGCCCAG
  CAGGAGTTGCTGCAGACCAAGCTGGAGCACCTGGGCCCCGGCGAGCCCCCGCCTGTGCTG
  CTCCTGCAGGATGACCGCCACTCCACGTCGTCCTCGGAGCAGGAGCGAGAGGGGGGAAGG
  ACACCCACGCTGGAGATCCTTAAGAGCCACATCTCAGGAATCTTCCGCCCCAAGTTCTCG
  CTCCCTCCACCGCTGCAGCTCATTCCGGAGGTGCAGAAGCCCCTGCATGAGCAGCTGTGG
  TACCACGGGGCCATCCCGAGGGCAGAGGTGGCTGAGCTGCTGGTGCACTCTGGGGACTTC
  CTGGTGCGGGAGAGCCAGGGCAAGCAGGAGTACGTGCTGTCGGTGCTGTGGGATGGTCTG
  CCCCGGCACTTCATCATCCAGTCCTTGGATAACCTGTACCGACTGGAAGGGGAAGGCTTT
  CCTAGCATTCCTTTGCTCATCGACCACCTACTGAGCACCCAGCAGCCCCTCACCAAGAAG
  AGTGGTGTTGTCCTGCACAGGGCTGTGCCCAAGGACAAGTGGGTGCTGAACCATGAGGAC
  CTGGTGTTGGGTGAGCAGATTGGACGGGGGAACTTTGGCGAAGTGTTCAGCGGACGCCTG
  CGAGCCGACAACACCCTGGTGGCGGTGAAGTCTTGTCGAGAGACGCTCCCACCTGACCTC
  AAGGCCAAGTTTCTACAGGAAGCGAGGATCCTGAAGCAGTACAGCCACCCCAACATCGTG
  CGTCTCATTGGTGTCTGCACCCAGAAGCAGCCCATCTACATCGTCATGGAGCTTGTGCAG
  GGGGGCGACTTCCTGACCTTCCTCCGCACGGAGGGGGCCCGCCTGCGGGTGAAGACTCTG
  CTGCAGATGGTGGGGGATGCAGCTGCTGGCATGGAGTACCTGGAGAGCAAGTGCTGCATC
  CACCGGGACCTGGCTGCTCGGAACTGCCTGGTGACAGAGAAGAATGTCCTGAAGATCAGT
  GACTTTGGGATGTCCCGAGAGGAAGCCGATGGGGTCTATGCAGCCTCAGGGGGCCTCAGA
  CAAGTCCCCGTGAAGTGGACCGCACCTGAGGCCCTTAACTACGGCCGCTACTCCTCCGAA
  AGCGACGTGTGGAGCTTTGGCATCTTGCTCTGGGAGACCTTCAGCCTGGGGGCCTCCCCC
  TATCCCAACCTCAGCAATCAGCAGACACGGGAGTTTGTGGAGAAGGGGGGCCGTCTGCCC
  TGCCCAGAGCTGTGTCCTGATGCCGTGTTCAGGCTCATGGAGCAGTGCTGGGCCTATGAG
  CCTGGGCAGCGGCCCAGCTTCAGCACCATCTACCAGGAGCTGCAGAGCATCCGAAAGCGG
  CATCGGTGA
  
  Clone variation with respect to NM_002005.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002005 unedited
  TCATAATTTGTAATACACTACTATAGGCGGCCGCGAATTCGGCACCAGCCCAAGAGCAGC
  TGCCCGTGCGGGTACCTCTAGCCCCGGGGCCTGGAGGAGCGGTGGGAGCTGGGGGCGCGG
  CAGGCAGGGGCAGAGCAGGCGTTCCGAGGGCCAGAGACCCACCCAGAACAGCACTATGGG
  CTTCTCTTCCGAGCTGTGCAGCCCCCAAGGCCACGGGGTCCTGCAGCAAATGCAGGAGGC
  CGAGCTTCGTCTACTGGAGGGCATGAGAAAGTGGATGGCCCAGCGGGTCAAGAGTGACAA
  GGGAGTATGCAGGACTGCTTCACCACATGTCCCTGCAGGACAGTGGGGGCCAGATCCGGG
  CCATCAGCCCTGACAGCCCCATCAGTCAGTCCTGGGCTGAGATCAACCAGCCAAACTGAG
  GGCCTGAGCCGCTTGCTGCGGCAGCACGCAGAAGATCTGAACTCAGGGCCCCTGAGCAAG
  CTGAGCCTGCTCATCCGGGAACGGCAGCAGCTTCGCAAGAACTACAGCGAGCAGTGGCAG
  CAGCTGCAGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGCTGAAGAACCAG
  TACCGAGCTCTGGCACGGGACAGTGCCCAAGCCAAGCGCAAGTACCATGAGGCCAGCAAA
  ACAANGACCGTGACAAGGCTAAGACAAGTATGTGCGCAGCCTGTGGAATCTCTTTGCTCA
  CCACAACCGCTATGTGCTTGGGCGTGCGGGCTGCGCATCTACACCACCATCAAACCACCA
  TCTCTGCTGCCGGNCTGCTGCGGTACTGCAAGACTGCAGAANGAGAATGCTGATNCTGAA
  AGAAANCTGCAGAATACTGGAAATTACANCTGTGCAGAATAAGGGGTGCCATTCACCGGA
  AAGGCTGAGCTGCTGCCGCATCAACTGAGCTGATACAAGCTCTGGAAATATGGTCGAACT
  GACTCACTTGGTAGTTNA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002005 unedited
  GGACCCTAAGGGTGATGGCACCTNCCTGCNAGGTANATCACTGGCGNAGGGTCACAGGGC
  ATGCCACCCGGGCTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT
  TTTTTTTTTTTTTTTTTTCAGTGGGCACAAGTGGTTTTATTGTTTCTGCCCGGAAGAGGA
  AGCCCTGGCAGCAGCAGGGACACAGAGAGGACACGGCTCTTTTTCCTGCCGGCAGTGTGG
  ATGCTGGTGGCAGGAGTCCAGGACTGTGAAGAGCTGTCAGCATATGAGCTGGAGCCGCTG
  ATGAGCTGCACCTAGGCCTGCAGAGGCCACCAGCTTGAGAAGGGGGTCCCAGCCTCACCG
  ATGCCGCTTTCGGATGCTCTGCAGCTCCTGGTATATGGTGCTGAAGCTGGGCCGCTGCCC
  AGGCTCATAGGCCCAGCTCTGCTCCATGAGCCTGAACACGGCATCAGGACACAGCTCTGG
  GCAGGGCAGACGGCCCCCCTTCTCCACAAACTCCCGTGTCTGCTGATTGCTGAGGTTGGG
  ATAGGGGGAGGCCCCCAGGCTGAAGGTCTCCCTTAGCAAGATGCCTAAGCTCCACATTTC
  GCTTTCGGAGGAGTAGCGGCCGTAGTTAAGGGCCTCAAGTGCGGTCCACTTCACGGGGGA
  CTTGTCTGAGGCCCCCTGATGCTGCCTAGACCCTATGGGCTTCCTCTCGGGACATCCCAT
  AGTCACTGATCTTCAGGACATTCTTCTCTGTCCCCGGGCTTTTTCCGATCACCCAGGTCC
  CGGTGGGTGCAACTTTTGCTCTTCCGGTTCTCCTTGCCGCCGTTTGTTTCCCCCCCCCTC
  TGGTCGGTATTCTCACCCGCGGTCGGCCCCCCTTCTTCCGGNGGAAGGTAAGGATTCCCC
  ACCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002005
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002005.2, NP_001996.1
• RefSeq Size: 2762 bp
• RefSeq ORF: 2469 bp
• Locus ID: 2242
• Cytogenetics: 15q26.1
• Domains: pkinase, SH2, FCH, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Axon guidance
• Gene Summary: 'This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).