D Amino Acid Oxidase (DAO) (NM_001917) Human Untagged Clone

CAT#: SC118941

DAO (untagged)-Human D-amino-acid oxidase (DAO)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DAO
• Synonyms: DAAO; DAMOX; OXDA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118941 sequence for NM_001917 edited (data generated by NextGen Sequencing)
  ATGCGTGTGGTGGTGATTGGAGCAGGAGTCATCGGGCTGTCCACCGCCCTCTGCATCCAT
  GAGCGCTACCACTCAGTCCTGCAGCCACTGGACATAAAGGTCTACGCGGACCGCTTCACC
  CCACTCACCACCACCGACGTGGCTGCCGGCCTCTGGCAGCCCTACCTTTCTGACCCCAAC
  AACCCACAGGAGGCGGACTGGAGCCAACAGACCTTTGACTATCTCCTGAGCCATGTCCAT
  TCTCCCAACGCTGAAAACCTGGGCCTGTTCCTAATCTCGGGCTACAACCTCTTCCATGAA
  GCCATTCCGGACCCTTCCTGGAAGGACACAGTTCTGGGATTTCGGAAGCTGACCCCCAGA
  GAGCTGGATATGTTCCCAGATTACGGCTATGGCTGGTTCCACACAAGCCTAATTCTGGAG
  GGAAAGAACTATCTACAGTGGCTGACTGAAAGGTTAACTGAGAGGGGAGTGAAGTTCTTC
  CAGCGGAAAGTGGAGTCTTTTGAGGAGGTGGCAAGAGAAGGCGCAGACGTGATTGTCAAC
  TGCACTGGGGTATGGGCTGGGGCGCTACAACGAGACCCCCTGCTGCAGCCAGGCCGGGGG
  CAGATCATGAAGGTGGACGCCCCTTGGATGAAGCACTTCATTCTCACCCATGACCCAGAG
  AGAGGCATCTACAATTCCCCGTACATCATCCCAGGGACCCAGACAGTTACTCTTGGAGGC
  ATCTTCCAGTTGGGAAACTGGAGTGAACTAAACAATATCCAGGACCACAACACCATTTGG
  GAAGGCTGCTGCAGACTGGAGCCCACACTGAAGAATGCAAGAATTATTGGTGAACGAACT
  GGCTTCCGGCCAGTACGCCCCCAGATTCGGCTAGAAAGAGAACAGCTTCGCACTGGACCT
  TCAAACACAGAGGTCATCCACAACTATGGCCATGGAGGCTACGGGCTCACCATCCACTGG
  GGATGTGCCCTGGAGGCAGCCAAGCTCTTTGGGAGAATCCTGGAAGAAAAGAAATTGTCC
  AGAATGCCACCATCCCACCTCTGA
  
  Clone variation with respect to NM_001917.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001917 unedited
  AGGATTTGTATACGACTTCTATAGGGCGGCCGCGAATTCGCACGAGGGAGATCCAGCCTC
  TCAAACATCCAGCAGAGAGACCATAGGCTGCTGCAATGCGTGTGGTGGTGATTGGAGCAG
  GAGTCATCGGGCTGTCCACCGCCCTCTGCATCCATGAGCGCTACCACTCAGTCCTGCAGC
  CACTGGACATAAAGGTCTACGCGGACCGCTTCACCCCACTCACCACCACCGACGTGGCTG
  CCGGCCTCTGGCAGCCCTACCTTTCTGACCCCAACAACCCACAGGAGGCGGACTGGAGCC
  AACAGACCTTTGACTATCTCCTGAGCCATGTCCATTCTCCCAACGCTGAAAACCTGGGCC
  TGTTCCTAATCTCGGGCTACAACCTCTTCCATGAAGCCATTCCGGACCCTTCCTGGAAGG
  ACACAGTTCTGGGATTTCGGAAGCTGACCCCCAGAGAGCTGGATATGTTCCCAGATTACG
  GCTATGGCTGGTTCCACACAAGCCTAATTCTGGAGGGAAAGAACTATCTACAGTGGCTGA
  CTGAAAGGTTAACTGAGAGGGGAGTGAAGTTCTTCCAGCGGAAAGTGGAGTCTTTTGAGG
  AGGTGGCAAGAGAAGGCGCAGACGTGATTGTCAACTGCACTGGGGTATGGGCTGGGGCGC
  TACAACGAGACCCCCTGCTGCAGCCCAGCCCNGGGGCAGATCATGAAAGTGGACGCCCCT
  TGGATGAAGCACTTTATTCTCACCCATGACCCCAGAGAGAAGCATCTACCATTCCCCCGT
  ACATCATCCCCAGGACCCAGACAGTTACTCTTGGAGGCATCCTCCAGTTGGGAAACTGGA
  GTGAACTAAACATATCCAGGACCACACACCATTTGTGGAAGCTGCTGCAGACTGAAGCCC
  AACTGAAGATGCCAGATNTATTGGTGACGAACTGGCTTCCTCCCATCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001917 unedited
  CGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGCAGGACTTTTCAGAACCTTT
  AATATGTTAGTACAACTTGTAATCAGGTTACTTAGCCTCAATTATCCTCCATTTTCTGTG
  GCTCTGGGCAGTTGGCCTCTTTGATTTTCTGAGCTGTCCTTTCTTCTGAAGACTCATGGA
  ATGACAGCCTCAGCTGTTCTTTATAATGCCAGACCCAGAGAAGGTAGAGGGATTTCAGTG
  ATGAGAGGGGCCCCATGTTGGGCTGAACCCTTCTCCAGGCACTGACTTTGTGGCTTTCTC
  TCACCTCATGCTTCTTTGAGGAAAGAAGTGAGGGAGAAGCAATGGCTTATGAAGGAGCAC
  ATTGATTCATTGGCTGAGGGGAGAAGGGAGTTCTTGTGGGGGGAGGCAGCAGTCACTGGA
  GTCTTCAGAGGTGGGATGGTGGCATTCTGGACAATTTCTTTTCTTCCAGGATTCTCCCAA
  AGAGCTTGGCTGCCTCCAGGGCACATCCCCAGTGGATGGTGAGCCCGTAGCCTCCATGGC
  CATAGTTGTGGATGACCTCTGTGTTTGAAGGTCCAGTGCGAAGCTGTTCTCTTTCTAGCC
  GAATCTGGGGGCGTACTGGCCGGAAGCCAGTTCGTTCACCAATAATTCTTGCATTCTTCA
  GTGTGGGCTCCAGTCTGCAGCAGCCTTCCCAAATGGTGTTGTGGTCCTGGATATTGTTTA
  GTTCACTCCAGTTTCCCAACTGGAAGATGCCTCCAAGAGTAACTGTCTGGGTCCCTGGGA
  TGATGTACGGGGCATTGTAAATGCCTCTCTCTGGCTCATGGGTGAGAATGAAGTGCTTCT
  CCCAGGGGCGTCCACCTTCTGATCTGCCCCCGCCTCGCTGANCANGGGGTCTCCGTGTAA
  CGCCCCACCCTACCCATGCCAGTGGACATCACTCTGCGCCTCTCTTGCACTCCCAAAAGA
  CCCACTTTCGCTGGGAGACTTCCTCCCT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_001917
• Insert Size: 1590 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001917.3, NP_001908.2
• RefSeq Size: 1576 bp
• RefSeq ORF: 1044 bp
• Locus ID: 1610
• Cytogenetics: 12q24.11
• Domains: DAO
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, D-Arginine and D-ornithine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways
• Gene Summary: 'This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]'