CDA (NM_001785) Human Untagged Clone

CAT#: SC119015

CDA (untagged)-Human cytidine deaminase (CDA)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDA
• Synonyms: CDD
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001785 edited
  ATGGCCCAGAAGCGTCCTGCCTGCACCCTGAAGCCTGAGTGTGTCCAGCAGCTGCTGGTT
  TGCTCCCAGGAGGCCAAGCAGTCAGCCTACTGCCCCTACAGTCACTTTCCTGTGGGGGCT
  GCCCTGCTCACCCAGGAGGGGAGAATCTTCAAAGGGTGCAACATAGAAAATGCCTGCTAC
  CCGCTGGGCATCTGTGCTGAACGGACCGCTATCCAGAAGGCCGTCTCAGAAGGGTACAAG
  GATTTCAGGGCAATTGCTATCGCCAGTGACATGCAAGATGATTTTATCTCTCCATGTGGG
  GCCTGCAGGCAAGTCATGAGAGAGTTTGGCACCAACTGGCCCGTGTACATGACCAAGCCG
  GATGGTACGTATATTGTCATGACGGTCCAGGAGCTGCTGCCCTCCTCCTTTGGGCCTGAG
  GACCTGCAGAAGACCCAGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001785 unedited
  CACGAGGCCCGGGGTACCAACATGGCCCAGAAGCGTCCTGCCTGCACCCTGAAGCCTGAG
  TGTGTCCAGCAGCTGCTGGTTTGCTCCCAGGAGGCCAAGCAGTCAGCCTACTGCCCCTAC
  AGTCACTTTCCTGTGGGGGCTGCCCTGCTCACCCAGGAGGGGAGAATCTTCAAAGGGTGC
  AACATAGAAAATGCCTGCTACCCGCTGGGCATCTGTGCTGAACGGACCGCTATCCAGAAG
  GCCGTCTCAGAAGGGTACAAGGATTTCAGGGCAATTGCTATCGCCAGTGACATGCAAGAT
  GATTTTATCTCTCCATGTGGGGCCTGCAGGCAAGTCATGAGAGAGTTTGGCACCAACTGG
  CCCGTGTACATGACCAAGCCGGATGGTACGTATATTGTCATGACGGTCCAGGAGCTGCTG
  CCCTCCTCCTTTGGGCCTGAGGACCTGCAGAAGACCCAGTGACAGCCAGAGAATGCCCAC
  TGCCTGTAACAGCCACCTGGAGAACTTCATAAAGATGTCTCACAGCCCTGGGGACACCTG
  CCCAGTGGGCCCCAGCCCTACAGGGACTGGGCAAAGATGATGTTTCCAGATTACACTCCA
  GCCTGAGTCAGCACCCCTCCTAGCAACCTGCCTTGGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001785 unedited
  CGGCCCCCGGGGGGNNCNNNNNNCNNNNNNNNNNNNNAANNTTTGACTTTGACCCCCCGN
  CCGCATACNANGATCGNGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTCCCAGAGGTTCTGGGATGTTTATAATTAAAAAATTGCTCGGAACAGGATAAAA
  CCTTGGAAAGGCTGATGGGAAACCACCCCAAACTAGGCTGGACTTTAAAAAAGGGCCCCC
  AGGAAGGAAAGGAAAGGGGGGGCAGGGGGCGGCGGTTTTTTAATCCCCAAGGCAGGTTGT
  TAGGAGGGGTGCTGACTCAGGCTGGAGGGTAATCTGGAAACATCTTTTTTGCCCAGCCCC
  TGTAGGGCTGGGGCCCACTGGGCAGGTGTCCCCAGGGCTGGAAAACATTTTTATAAAGTT
  CTCCAGGGGGCTGTTACAGGCAGGGGGCATTCTTTGGCTGCCACTGGGTCTTTTGCAGGC
  CCTCAGGCCCAAAGGAGGAGGGCAGCATCTCCTGGACCGTCTTGACAATATACGTCCCAT
  CCGGCTTGGTCATGTCCACGGCCCAGTTGGGGCCAAACTCTTTAATGACTTGCCTGCAGG
  CCCCACATGGAAAGATAAAATCATCTTGCATGTCACTGGCAATAGCAATTGCCCTGAAAT
  CCTTGTACCCTTCTGAAACGGCCCTCTGGATAGCGGCCCGTTCACCACAAATGCCCAGCG
  GTTAACAGGCATTTTCTATGTTTGCCCCCTTTGAAGATTCTCCTTTCCTGGGGGACCGGG
  GCACCCCCCCCCAGAAAAGTGACTGTTGGGGCCAATAGGCCTAACTGCTTGGGCCTCCTT
  GGGACCAAACCACCATTTGTTGGACACCACTTAGCTTTTAGGGTGCAGGCCAGAACCCTT
  CTTGGGCCCATGGTTGGACCCCCGGGGCCTTCGTGCCCAAATTCCCGGGCCGCCCTTTTG
  GGGAGCCGTATTACAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001785
• ORF Size: 441 bp
• Insert Size: 910
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_001785.1, NP_001776.1
• RefSeq Size: 892
• RefSeq ORF: 441
• Locus ID: 978
• Domains: dCMP_cyt_deam
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
• Gene Summary: This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008]