CD68 (NM_001251) Human Untagged Clone

CAT#: SC119334

CD68 (untagged)-Human CD68 molecule (CD68), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD68
• Synonyms: GP110; LAMP4; SCARD1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001251, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGCTGGCTGTGCTTTTCTCGGGGGCCCTGCTGGGGCTACTGGCAGCCCAGGGGACAGGGAATGACT
  GTCCTCACAAAAAATCAGCTACTTTGCTGCCATCCTTCACGGTGACACCCACGGTTACAGAGAGCACTGG
  AACAACCAGCCACAGGACTACCAAGAGCCACAAAACCACCACTCACAGGACAACCACCACAGGCACCACC
  AGCCACGGACCCACGACTGCCACTCACAACCCCACCACCACCAGCCATGGAAACGTCACAGTTCATCCAA
  CAAGCAATAGCACTGCCACCAGCCAGGGACCCTCAACTGCCACTCACAGTCCTGCCACCACTAGTCATGG
  AAATGCCACGGTTCATCCAACAAGCAACAGCACTGCCACCAGCCCAGGATTCACCAGTTCTGCCCACCCA
  GAACCACCTCCACCCTCTCCGAGTCCTAGCCCAACCTCCAAGGAGACCATTGGAGACTACACGTGGACCA
  ATGGTTCCCAGCCCTGTGTCCACCTCCAAGCCCAGATTCAGATTCGAGTCATGTACACAACCCAGGGTGG
  AGGAGAGGCCTGGGGCATCTCTGTACTGAACCCCAACAAAACCAAGGTCCAGGGAAGCTGTGAGGGTGCC
  CATCCCCACCTGCTTCTCTCATTCCCCTATGGACACCTCAGCTTTGGATTCATGCAGGACCTCCAGCAGA
  AGGTTGTCTACCTGAGCTACATGGCGGTGGAGTACAATGTGTCCTTCCCCCACGCAGCACAGTGGACATT
  CTCGGCTCAGAATGCATCCCTTCGAGATCTCCAAGCACCCCTGGGGCAGAGCTTCAGTTGCAGCAACTCG
  AGCATCATTCTTTCACCAGCTGTCCACCTCGACCTGCTCTCCCTGAGGCTCCAGGCTGCTCAGCTGCCCC
  ACACAGGGGTCTTTGGGCAAAGTTTCTCCTGCCCCAGTGACCGGTCCATCTTGCTGCCTCTCATCATCGG
  CCTGATCCTTCTTGGCCTCCTCGCCCTGGTGCTTATTGCTTTCTGCATCATCCGGAGACGCCCATCCGCC
  TACCAGGCCCTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001251 unedited
  NGTCACCATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCTTTGGGTG
  AGGCGGTTCAGCCATGAGGCTGGCTGTGCTTTTCTCGGGGGCCCTGCTGGGGCTACTGGC
  AGCCCAGGGGACAGGGAATGACTGTCCTCACAAAAAATCAGCTACTTTGCTGCCATCCTT
  CACGGTGACACCCACGGTTACAGAGAGCACTGGAACAACCAGCCACAGGACTACCAAGAG
  CCACAAAACCACCACTCACAGGACAACCACCACAGGCACCACCAGCCACGGACCCACGAC
  TGCCACTCACAACCCCACCACCACCAGCCATGGAAACGTCACAGTTCATCCAACAAGCAA
  TAGCACTGCCACCAGCCAGGGACCCTCAACTGCCACTCACAGTCCTGCCACCACTAGTCA
  TGGAAATGCCACGGTTCATCCAACAAGCAACAGCACTGCCACCAGCCCAGGATTCACCAG
  TTCTGCCCACCCAGAACCACCTCCACCCTCTCCGAATCCTAGCCCAACCTCCAAGGAGAC
  CATTGGAGACTACACGTGGACCAATGGTTCCCAGCCCCGTGTCCACCTCCAAGCCCAGAT
  TCAGATTCGAGTCATGTACACAACCCAGGGTGGAGGAGAGGCCTGNGGCATCTCTGTACT
  GAACCCCAACAAAACCAAGGTCCAGGGAACCTGTGAGGGTGCCCATCCNCACCTGCTTCT
  CTCATTCCCCTATGGACACCTCAGCTNTGGATTCATGCANGACCTNCAGCAGAAGGTTGT
  CTACCTGAGCTACATGGCGGTGGAGTACAATGTGTCCCTTCCCCACGCAGCACAGTGGAC
  ATTCTCGGCTCAGATGCATNCCTTCGAGACTCCAGCACCCCTGGNNGCAGAGCTCAGTGC
  AGCACTCGAGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001251 unedited
  TATGAACCGCGGCCGCAATCTAAGATCGAGTTTTTTTTTTTTTTTTTTGACAAAAAACTC
  ATGGCTTTTAATCCTGGCAGGACAAGGGAAAACCCCGTCAAAAATTTGCATAAATTTTGC
  TGCTCTCCTGCTGGGGGGGGGGGGGGGGCCCATTCCTCCACATTAAAAAAAATTCTTTCC
  CTCCTTTCTCCCAACTGCATAATCTAATATTAATTAATTTAAAACATTCTGCCTCTTCCC
  CCCAGCCTGAATTCCATTGCCCCAATCTTGCCTAATTGCCCCAATAACGGCTCACTGAAA
  CCTCCACCTCCTGGTTTAAACCATTTCTCCCTCACCCTCCCAATTACCTGGAATTACAGC
  CCACCTGGAATTACCCCCCCACACCTGCCTAATTGAATTTTAATAAAAAACAGGTTTTAA
  CCATTTTGCCCAGCCTGTCCTAAAACTCCTAACCTCAATTAACCCACCTCCCTAACCCTC
  CCAAATTGCTGGAATAACAGCCATAACCCGTAATCCCCGGTTTTCTTTTTGTCCTTAAAA
  AAAGGAAAGAAAATAAACATTGTCTTTAACCCATTTCCTTTTCAAGAAAAAAAGGTTACC
  CCCCCACAAAACCCAAACCCCTTAATTGCCCTGGGCTTTAAACCAAATTCTAAAAAGCCC
  TGTTAGCCGAATGGCCCTTCTCCGTATAATCCAAAAACCATACCCCCCAGGCCAAAAAGC
  CCAAAAAAAATCAGCCCCCTCATAAAAACCCCCAAAAATGACACCCTTCACTTGGGCCAG
  GAAAAAACTTTGCCCCAAAAACCCCTTTTTGGGCCACCTATACACCCTGAACCCCCAAGA
  AAAACACTTCAAGGTGCACACCTTTTGAACAATATACCCCCCATCTCCTAAAACTAAACC
  CTTCCCCAAGCGTCCTTAGAAATCTTCAAAGAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001251
• Insert Size: 1730 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001251.1, NP_001242.1
• RefSeq Size: 1872 bp
• RefSeq ORF: 1872 bp
• Locus ID: 968
• Cytogenetics: 17p13.1
• Domains: Lamp
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Lysosome
• Gene Summary: 'This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (A).