CD68 (NM_001251) Human Untagged Clone

CAT#: SC320304

CD68 (untagged)-Human CD68 molecule (CD68), transcript variant 1


  "NM_001251" in other vectors (7)

Reconstitution Protocol

USD 760.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CD68
Synonyms GP110; LAMP4; SCARD1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_001251.2 GGCACGAGGGGGAGCAGGGTTGAGCAACTGGTGCAGACAGCCTAGCTGGACTTTGGGTGA
GGCGGTTCAGCCATGAGGCTGGCTGTGCTTTTCTCGGGGGCCCTGCTGGGGCTACTGGCA
GCCCAGGGGACAGGGAATGACTGTCCTCACAAAAAATCAGCTACTTTGCTGCCATCCTTC
ACGGTGACACCCACGGTTACAGAGAGCACTGGAACAACCAGCCACAGGACTACCAAGAGC
CACAAAACCACCACTCACAGGACAACCACCACAGGCACCACCAGCCACGGACCCACGACT
GCCACTCACAACCCCACCACCACCAGCCATGGAAACGTCACAGTTCATCCAACAAGCAAT
AGCACTGCCACCAGCCAGGGACCCTCAACTGCCACTCACAGTCCTGCCACCACTAGTCAT
GGAAATGCCACGGTTCATCCAACAAGCAACAGCACTGCCACCAGCCCAGGATTCACCAGT
TCTGCCCACCCAGAACCACCTCCACCCTCTCCGAGTCCTAGCCCAACCTCCAAGGAGACC
ATTGGAGACTACACGTGGACCAATGGTTCCCAGCCCTGTGTCCACCTCCAAGCCCAGATT
CAGATTCGAGTCATGTACACAACCCAGGGTGGAGGAGAGGCCTGGGGCATCTCTGTACTG
AACCCCAACAAAACCAAGGTCCAGGGAAGCTGTGAGGGTGCCCATCCCCACCTGCTTCTC
TCATTCCCCTATGGACACCTCAGCTTTGGATTCATGCAGGACCTCCAGCAGAAGGTTGTC
TACCTGAGCTACATGGCGGTGGAGTACAATGTGTCCTTCCCCCACGCAGCACAGTGGACA
TTCTCGGCTCAGAATGCATCCCTTCGAGATCTCCAAGCACCCCTGGGGCAGAGCTTCAGT
TGCAGCAACTCGAGCATCATTCTTTCACCAGCTGTCCACCTCGACCTGCTCTCCCTGAGG
CTCCAGGCTGCTCAGCTGCCCCACACAGGGGTCTTTGGGCAAAGTTTCTCCTGCCCCAGT
GACCGGTCCATCTTGCTGCCTCTCATCATCGGCCTGATCCTTCTTGGCCTCCTCGCCCTG
GTGCTTATTGCTTTCTGCATCATCCGGAGACGCCCATCCGCCTACCAGGCCCTCTGAGCA
TTTGCTTCAAACCCCAGGGCACTGAGGGGGTTGGGGTGTGGTGGGGGGGTACCCTTATTT
CCTCGACACGCAACTGGCTCAAAGACAATGTTATTTTCCTTCCCTTTCTTGAAGAACAAA
AAGAAAGCCGGGCATGACGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAG
GTGGATCACTGGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCT
CTACTAAAAATACAATTAGCCAGGTGTGGCGGCGTAATCCCAGCTGGCCTGTAATCCCAG
CTACTTGGGAGGCTGAGGCAGAACTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCG
TCATCGCGCCACTAAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCAGA
CTGTCTCAAATAAATAAATATGAGATAATGCAGTCGGGAGAAGGGAGGGAGAGAATTTTA
TTAAATGTGACGAACTGCCCCCCCCCCCCCAGCAGGAGAGCAGCAAAATTTATGCAAATC
TTTGACGGGGTTTTCCTTGTCCTGCCAGGATTAAAAGCCATGAGTTTCTTAAAAAAAAAA
AAAAAAAA
Restriction Sites Please inquire     
ACCN NM_001251
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001251.2, NP_001242.2
RefSeq Size 1872 bp
RefSeq ORF 1065 bp
Locus ID 968
Cytogenetics 17p13.1
Domains Lamp
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome
Gene Summary 'This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (A).

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