BMP1 (NM_006129) Human Untagged Clone

CAT#: SC119391

BMP1 (untagged)-Human bone morphogenetic protein 1 (BMP1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BMP1
• Synonyms: OI13; PCOLC; PCP; PCP2; TLD
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119391 sequence for NM_006129 edited (data generated by NextGen Sequencing)
  ATGCCCGGCGTGGCCCGCCTGCCGCTGCTGCTCGGGCTGCTGCTGCTCCCGCGTCCCGGC
  CGGCCGCTGGACTTGGCCGACTACACCTATGACCTGGCGGAGGAGGACGACTCGGAGCCC
  CTCAACTACAAAGACCCCTGCAAGGCGGCTGCCTTTCTTGGGGACATTGCCCTGGACGAA
  GAGGACCTGAGGGCCTTCCAGGTACAGCAGGCTGTGGATCTCAGACGGCACACAGCTCGT
  AAGTCCTCCATCAAAGCTGCAGTTCCAGGAAACACTTCTACCCCCAGCTGCCAGAGCACC
  AACGGGCAGCCTCAGAGGGGAGCCTGTGGGAGATGGAGAGGTAGATCCCGTAGCCGGCGG
  GCGGCGACGTCCCGACCAGAGCGTGTGTGGCCCGATGGGGTCATCCCCTTTGTCATTGGG
  GGAAACTTCACTGGTAGCCAGAGGGCAGTCTTCCGGCAGGCCATGAGGCACTGGGAGAAG
  CACACCTGTGTCACCTTCCTGGAGCGCACTGACGAGGACAGCTATATTGTGTTCACCTAT
  CGACCTTGCGGGTGCTGCTCCTACGTGGGTCGCCGCGGCGGGGGCCCCCAGGCCATCTCC
  ATCGGCAAGAACTGTGACAAGTTCGGCATTGTGGTCCACGAGCTGGGCCACGTCGTCGGC
  TTCTGGCACGAACACACTCGGCCAGACCGGGACCGCCACGTTTCCATCGTTCGTGAGAAC
  ATCCAGCCAGGGCAGGAGTATAACTTCCTGAAGATGGAGCCTCAGGAGGTGGAGTCCCTG
  GGGGAGACCTATGACTTCGACAGCATCATGCATTACGCTCGGAACACATTCTCCAGGGGC
  ATCTTCCTGGATACCATTGTCCCCAAGTATGAGGTGAACGGGGTGAAACCTCCCATTGGC
  CAAAGGACACGGCTCAGCAAGGGGGACATTGCCCAAGCCCGCAAGCTTTACAAGTGCCCA
  GCCTGTGGAGAGACCCTGCAAGACAGCACAGGCAACTTCTCCTCCCCTGAATACCCCAAT
  GGCTACTCTGCTCACATGCACTGCGTGTGGCGCATCTCTGTCACACCCGGGGAGAAGATC
  ATCCTGAACTTCACGTCCCTGGACCTGTACCGCAGCCGCCTGTGCTGGTACGACTATGTG
  GAGGTCCGAGATGGCTTCTGGAGGAAGGCGCCCCTCCGAGGCCGCTTCTGCGGGTCCAAA
  CTCCCTGAGCCTATCGTCTCCACTGACAGCCGCCTCTGGGTTGAATTCCGCAGCAGCAGC
  AATTGGGTTGGAAAGGGCTTCTTTGCAGTCTACGAAGCCATCTGCGGGGGTGATGTGAAA
  AAGGACTATGGCCACATTCAATCGCCCAACTACCCAGACGATTACCGGCCCAGCAAAGTC
  TGCATCTGGCGGATCCAGGTGTCTGAGGGCTTCCACGTGGGCCTCACATTCCAGTCCTTT
  GAGATTGAGCGCCACGACAGCTGTGCCTACGACTATCTGGAGGTGCGCGACGGGCACAGT
  GAGAGCAGCACCCTCATCGGGCGCTACTGTGGCTATGAGAAGCCTGATGACATCAAGAGC
  ACGTCCAGCCGCCTCTGGCTCAAGTTCGTCTCTGACGGGTCCATTAACAAAGCGGGCTTT
  GCCGTCAACTTTTTCAAAGAGGTGGACGAGTGCTCTCGGCCCAACCGCGGGGGCTGTGAG
  CAGCGGTGCCTCAACACCCTGGGCAGCTACAAGTGCAGCTGTGACCCCGGGTACGAGCTG
  GCCCCAGACAAGCGCCGCTGTGAGGCTGCTTGTGGCGGATTCCTCACCAAGCTCAACGGC
  TCCATCACCAGCCCGGGCTGGCCCAAGGAGTACCCCCCCAACAAGAACTGCATCTGGCAG
  CTGGTGGCCCCCACCCAGTACCGCATCTCCCTGCAGTTTGACTTATTTGAGACAGAGGGC
  AATGATGTGTGCAAGTACGACTTCGTGGAGGTGCGCAGTGGACTCACAGCTGACTCCAAG
  CTGCATGGCAAGTTCTGTGGTTCTGAGAAGCCCGAGGTCATCACCTCCCAGTACAACAAC
  ATGCGCGTGGAGTTCAAGTCCGACAACACCGTGTCCAAAAAGGGCTTCAAGGCCCACTTC
  TTCTCAGACAAGGACGAGTGCTCCAAGGATAACGGCGGCTGCCAGCAGGACTGCGTCAAC
  ACGTTCGGCAGTTATGAGTGCCAATGCCGCAGTGGCTTCGTCCTCCATGACAACAAGCAC
  GACTGCAAAGAAGCCGGCTGTGACCACAAGGTGACATCCACCAGTGGTACCATCACCAGC
  CCCAACTGGCCTGACAAGTATCCCAGCAAGAAGGAGTGCACGTGGGCCATCTCCAGCACC
  CCCGGGCACCGGGTCAAGCTGACCTTCATGGAGATGGACATCGAGTCCCAGCCTGAGTGT
  GCCTACGACCACCTAGAGGTGTTCGACGGGCGAGACGCCAAGGCCCCCGTCCTCGGCCGC
  TTCTGTGGGAGCAAGAAGCCCGAGCCCGTCCTGGCCACAGGCAGCCGCATGTTCCTGCGC
  TTCTACTCAGATAACTCGGTCCAGCGAAAGGGCTTCCAGGCCTCCCACGCCACAGAGTGC
  GGGGGCCAGGTACGGGCAGACGTGAAGACCAAGGACCTTTACTCCCACGCCCAGTTTGGC
  GACAACAACTACCCTGGGGGTGTGGACTGTGAGTGGGTCATTGTGGCCGAGGAAGGCTAC
  GGCGTGGAGCTCGTGTTCCAGACCTTTGAGGTGGAGGAGGAGACCGACTGCGGCTATGAC
  TACATGGAGCTCTTCGACGGCTACGACAGCACAGCCCCCAGGCTGGGGCGCTACTGTGGC
  TCAGGGCCTCCTGAGGAGGTGTACTCGGCGGGAGATTCTGTCCTGGTGAAGTTCCACTCG
  GATGACACCATCACCAAAAAAGGTTTCCACCTGCGATACACCAGCACCAAGTTCCAGGAC
  ACACTCCACAGCAGGAAGTGA
  
  Clone variation with respect to NM_006129.4
  1905 c=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006129 unedited
  TTCNCCGCCCGNAGNCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAG
  AGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAA
  TTCGGCACGAGGGAGGACGAGCGCGGAGCCGCGGGCCGAGCGGGGGGCGGGAGACAGGAA
  GGAGGGAGGCGAGCAGAGGGAAGGGGAAGAGGTCGGGGAGCGAGGGCGGGAGCGGTCGCG
  GTCGCGATCGAGCAAGCAAGCGGGCGAGAGGACGCCCTCCCCTGGCCTCCAGTGCGCCGC
  TTCCCTCGCCGCCGCCCCGCCAGCATGCCCGGCGTGGCCCGCCTGCCGCTGCTGCTCGGG
  CTGCTGCTGCTCCCGCGTCCCGGCCGGCCGCTGGACTTGGCCGACTACACCTATGACCTG
  GCGGAGGAGGACGACTCGGAGCCCCTCAACTACAAAGACCCCTGCAAGGCGGCTGCCTTT
  CTTGGGGACATTGCCCTGGACGAAGAGGACCTGAGGGCCTTCCAGGTACAGCAGGCTGTG
  GATCTCAGACGGCACACAGCTCGTAAGTCCTCCATCANAGCTGCAGTTCCAGGAAACACT
  TCTACCCCCAGCTGCCAGAGCACCAACGGGCAGCCTCAGAGGGGAGCCTGNTGGAGATGG
  AGAGGTAGATCCCGTAGCCGGCGGGCGGCGACGTCCNGACCAGAGCGTGTGTGGCCCGAT
  GGGGTCATCCCCTTTGTCATTGGNGGAAACTTCACTGGTAGCCAGAGGGCAGTCTTCCGG
  CAGGNCCATGAGCACTGGGAGAGCACACCTGTGTCACCTTTCTGGAGCGACTGACGAGGA
  CAGTATATTGTGTCACCTTCGACTTGCGGNTGCTGCTCTACGTGGGTCGCGCGGGGGGGG
  CCCCAGCCATCTCATCGCAGACTGGGCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006129
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006129.2, NP_006120.1
• RefSeq Size: 3552 bp
• RefSeq ORF: 2961 bp
• Locus ID: 649
• Cytogenetics: 8p21.3
• Protein Families: Druggable Genome, Protease
• Gene Summary: 'This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]'
  Transcript Variant: This variant (3, also known as BMP1-3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is longer than isoform 1.