CYP4F3 (NM_000896) Human Untagged Clone

CAT#: SC119595

CYP4F3 (untagged)-Human cytochrome P450, family 4, subfamily F, polypeptide 3 (CYP4F3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYP4F3
• Synonyms: CPF3; CYP4F; CYPIVF3; LTB4H
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000896 edited
  GGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAG
  AATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGGTGGGACAAGGT
  GCTCCTGACAGAAGGATGCCACAGCTGAGCCTGTCCTCGCTGGGCCTTTGGCCAATGGCA
  GCATCCCCGTGGCTGCTCCTGCTGCTGGTTGGGGCCTCCTGGCTCCTGGCCCGCATCCTG
  GCCTGGACCTATACCTTCTATGACAACTGCTGCCGCCTCCGGTGTTTCCCGCAACCCCCG
  AAACGGAATTGGTTCTTGGGTCACCTGGGCCTGATTCACAGCTCGGAGGAAGGTCTCCTA
  TACACACAAAGCCTGGCATGCACCTTCGGTGATATGTGCTGCTGGTGGGTGGGGCCCTGG
  CACGCAATCGTCCGCATCTTCCACCCCACCTACATCAAGCCTGTGCTCTTTGCTCCAGCT
  GCCATTGTACCAAAGGACAAGGTCTTCTACAGCTTCCTGAAGCCCTGGCTGGGGGATGGG
  CTCCTGCTGAGTGCTGGTGAAAAGTGGAGCCGCCACCGTCGGATGCTGACGCCTGCCTTC
  CATTTCAACATCCTGAAGCCCTATATGAAGATTTTCAATGAGAGTGTGAACATCATGCAT
  GCCAAGTGGCAGCTCCTGGCCTCAGAGGGTAGTGCCCGTCTGGACATGTTTGAGCACATC
  AGCCTCATGACCTTGGACAGTCTACAGAAATGTGTCTTCAGCTTTGACAGCCATTGCCAG
  GAGAAGCCCAGTGAATATATTGCCGCCATCTTGGAGCTCAGTGCCCTTGTGACAAAAAGA
  CACCAGCAGATCCTCCTGTACATAGACTTCCTGTATTATCTCACCCCTGATGGGCAGCGT
  TTCCGCAGGGCCTGCCGCCTGGTGCACGACTTCACAGATGCCGTCATCCAGGAGCGGCGC
  CGCACCCTCCCTAGCCAGGGTGTTGATGACTTCCTCCAAGCCAAGGCCAAATCCAAGACT
  TTGGACTTCATTGATGTACTCCTGCTGAGCAAGGATGAAGATGGGAAGAAGTTGTCCGAT
  GAGGACATAAGAGCAGAAGCTGACACCTTTATGTTTGAGGGCCATGACACCACAGCCAGT
  GGTCTCTCCTGGGTCCTGTACCACCTTGCAAAGCACCCAGAATACCAGGAGCGCTGTCGG
  CAGGAGGTGCAAGAGCTTCTGAAGGACCGTGAGCCTAAAGAGATTGAATGGGACGACCTG
  GCCCAGCTGCCCTTCCTGACCATGTGCATTAAGGAGAGCCTGAGGCTGCATCCCCCAGTC
  CCTGCCGTCTCTCGCTGCTGCACCCAAGACATTGTGCTCCCAGACGGCCGGGTCATCCCC
  AAAGGCATTATCTGCCTCATCAGTGTTTTTGGAACCCATCACAACCCAGCCGTGTGGCCG
  GACCCTGAGGTCTATGACCCCTTTCGCTTTGACCCAAAGAACATCAAGGAGAGGTCACCT
  CTGGCTTTTATTCCCTTCTCAGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCGATG
  GCGGAGATGAAGGTGGTCCTGGGGCTCACGCTGCTGCGCTTCCGCGTCCTGCCTGACCAC
  ACCGAGCCCCGCAGGAAGCCGGAGCTGGTCCTGCGCGCAGAGGGCGGACTTTGGCTGCGG
  GTGGAGCCCCTGAGCTGAGTTCTGCAGAGACCCACTCTGACCCCACTAAAATGACCCCTG
  ATTCATCAAAAGTGAGGCCTAGAATTACCCTAAGACCCTGTTCCACAGTCCTGTATTCCA
  TCCTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000896 unedited
  NGAGCCTCAATTGTATACGACTTACTATAGGCGGCCGCGAATTCGCACCAGGTGGGACAA
  GGTGCTCCTGACAGAAGGATGCCACAGCTGAGCCTGTCCTCGCTGGGCCTTTGGCCAATG
  GCAGCATCCCCGTGGCTGCTCCTGCTGCTGGTTGGGGCCTCCTGGCTCCTGGCCCGCATC
  CTGGCCTGGACCTATACCTTCTATGACAACTGCTGCCGCCTCCGGTGTTTCCCGCAACCC
  CCGAAACGGAATTGGTTCTTGGGTCACCTGGGCCTGATTCACAGCTCGGAGGAAGGTCTC
  CTATACACACAAAGCCTGGCATGCACCTTCGGTGATATGTGCTGCTGGTGGGTGGGGCCC
  TGGCACGCAATCGTCCGCATCTTCCACCCCACCTACATCAAGCCTGTGCTCTTTGCTCCA
  GCTGCCATTGTACCAAAGGACAAGGTCTTCTACAGCTTCCTGAAGCCCTGGCTGGGGGAT
  GGGCTCCTGCTGAGTGCTGGTGAAAAGTGGAGCCGCCACCGTCGGATGCTGACGCCTGCC
  TTCCATTTCAACATCCTGAAGCCCTATATGAAGATTTTCAATGAGAGTGTGAACATCATG
  CATGCCAAGTGGCAGCTCCTGGCCTCAGAGGGTAGTGCCCGTCTGGACATGTTTGAGCAC
  ATCAGCCTCATGACCTTGGACAGTCTACAGAAATGTGTCTTCAGCTTTGACAGCCATTGC
  CAGGAGAAGCCCAGTGAATATATTGCCGCCATCTTGGAGCTCAGTGCCCTTGTGNACAAN
  AGACCCAGCAGATCCTCCTGTACATAGACTTCCTGTATTATCTCACCCCTGATGGGCAGC
  GTTTCCCGCAGGCCTGCCGCCTGGTGCACGACTTCACAGATGCCGTCATNCCAGAGCGGC
  GCCGCACCCTCCCTANCCAGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000896 unedited
  TTTACTCTGNACCCGCGGCCGCAATCTAGNGATCGGTTTTTTTTTTTTTTTTTTTTTTTT
  TGGTTCCTAAAAGATTTAATATCATGGGAAAGAGCTCACAACATATTCTTTTGTGAAGAA
  TCCAGATGGAAAAAGTATATATGAGCTGTAATAGCATGTTTAGGTAGAATTCACATAAAA
  ATCACTATTTCAACCATTCTAAAGTGTCTAATTCAATAGCATTTAGTGCACTCACAGTGT
  CGTGCTACCTTCATCACTATCTAGGTCCGGAACATTTTCACCATCCCAGGAGAAAACCCC
  ATCCTGATTAGCAGTCGCTCCTCAGTCCCACCTCCCCACAGCTGCTGAAAGCCACCAATC
  CACTATACATCTCTTCAGATTGGCCTGTTCTGGAAATTTCATATAAAAGGACAGTACACT
  ATGTGACCTTTTGCATCTGATGTCTTTCATTCAGTATCATGCATTCAAGGTTCATCCACA
  GTGTAGTGGGGATCACTGCTTCATTCCTTTTTATGGCTGTGTAATACTCCATTGTATGGA
  TGGACCATATTTTGNTTATCCTTTCATCTGGNAATATATAGCTTGGGGTTGTTTTCATCG
  TTTGGCTACTGTGAATAGGGCTGCCATGAACATTCACGCACAAGCGTCTTTCTGTTTGAA
  CACTTGTCTCAATTATTTTGAGTAGATATCTAGGATGGAATACAGGACTGTGGAACAGGG
  TCTTAAGGTAAATTCTAGCCTCACTTTTGATGAATCAGGGGTCATTTTAGTGGGGTCAGA
  ATGGGTCTCTGCAGAACTCAGCTCAAGGGCTCCACCCGCAGCCAAAGTTCGCCCTCTGCG
  CGCAGGAACAGCTCCGGCTTTCTGCGNGGTTCTGTTGTGTCAGGCCAGACCCGAANCGCA
  NNCACGTGAGCCCAGAACACCCTCATTTCCCCATGGNGACCCTGTCGGAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000896
• ORF Size: 1563 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_000896.1, NP_000887.1
• RefSeq Size: 5050
• RefSeq ORF: 1563
• Locus ID: 4051
• Domains: p450
• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways
• Gene Summary: This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2019]
  Transcript Variant: This variant (1) encodes isoform a, which is the same length but has internal differences compared to isoform b.