LKB1 (STK11) (NM_000455) Human Untagged Clone
CAT#: SC119871
STK11 (untagged)-Human serine/threonine kinase 11 (STK11)
"NM_000455" in other vectors (7)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | STK11 |
Synonyms | hLKB1; LKB1; PJS |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_000455 edited
ATGGAGGTGGTGGACCCGCAGCAGCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTG GGTATGGACACGTTCATCCACCGCATCGACTCCACCGAGGTCATCTACCAGCCGCGCCGC AAGCGGGCCAAGCTCATCGGCAAGTACCTGATGGGGGACCTGCTGGGGGAAGGCTCTTAC GGCAAGGTGAAGGAGGTGCTGGACTCGGAGACGCTGTGCAGGAGGGCCGTCAAGATCCTC AAGAAGAAGAAGTTGCGAAGGATCCCCAACGGGGAGGCCAACGTGAAGAAGGAAATTCAA CTACTGAGGAGGTTACGGCACAAAAATGTCATCCAGCTGGTGGATGTGTTATACAACGAA GAGAAGCAGAAAATGTATATGGTGATGGAGTACTGCGTGTGTGGCATGCAGGAAATGCTG GACAGCGTGCCGGAGAAGCGTTTCCCAGTGTGCCAGGCCCACGGGTACTTCTGTCAGCTG ATTGACGGCCTGGAGTACCTGCATAGCCAGGGCATTGTGCACAAGGACATCAAGCCGGGG AACCTGCTGCTCACCACCGGTGGCACCCTCAAAATCTCCGACCTGGGCGTGGCCGAGGCA CTGCACCCGTTCGCGGCGGACGACACCTGCCGGACCAGCCAGGGCTCCCCGGCTTTCCAG CCGCCCGAGATTGCCAACGGCCTGGACACCTTCTCCGGCTTCAAGGTGGACATCTGGTCG GCTGGGGTCACCCTCTACAACATCACCACGGGTCTGTACCCCTTCGAAGGGGACAACATC TACAAGTTGTTTGAGAACATCGGGAAGGGGAGCTACGCCATCCCGGGCGACTGTGGCCCC CCGCTCTCTGACCTGCTGAAAGGGATGCTTGAGTACGAACCGGCCAAGAGGTTCTCCATC CGGCAGATCCGGCAGCACAGCTGGTTCCGGAAGAAACATCCTCCGGCTGAAGCACCAGTG CCCATCCCACCGAGCCCAGACACCAAGGACCGGTGGCGCAGCATGACTGTGGTGCCGTAC TTGGAGGACCTGCACGGCGCGGACGAGGACGAGGACCTCTTCGACATCGAGGATGACATC ATCTACACTCAGGACTTCACGGTGCCCGGACAGGTCCCAGAAGAGGAGGCCAGTCACAAT GGACAGCGCCGGGGCCTCCCCAAGGCCGTGTGTATGAACGGCACAGAGGCGGCGCAGCTG AGCACCAAATCCAGGGCGGAGGGCCGGGCCCCCAACCCTGCCCGCAAGGCCTGCTCCGCC AGCAGCAAGATCCGCCGGCTGTCGGCCTGCAAGCAGCAGTGA >OriGene 5' read for NM_000455 unedited
CATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCGGACGCC CCCAGCCCCCCGAACGCTCGCCCGGGCCGGCGGGAGTCGGCGCCCCCCGGGAGGTCCGCT CGGTCGTCCGCGGCGGAGCGTTTGCTCCTGGGACAGGCGGTGGGACCGGGGCGTCGCCGG AGACGCCCCCAGCGAAGTTGGGCTCTCCAGGTGTGGGGGTCCCGGGGGGTAGCGACGTCG CGGACCCGGCCTGTGGGATGGGCGGCCCGGAGAAGACTGCGCTCGGCCGTGTTCATACTT GTCCGTGGGCCTGAGGTCCCCGGAGGATGACCTAGCACTGAAAAGCCCCGGCCGGCCTCC CCAGGGTCCCCGAGGACGAAGTTGACCCTGACCGGGCCGTCTCCCAGTTCTGAGGCCCGG GTCCCACTGGAACTCGCGTCTGAGCCGCCGTCCCGGACCCCCGGTGCCCGCCGGTCCGCA GACCCTGCACCGGGCTTGGACTCGCAGCCGGGACTGACGTGTAGAACAATCGTTTCTGTT GGAAGAAGGGTTTTTCCCTTCCTTTTGGGGTTTTTGTTGCCTTTTTTTTTTCTTTTTTCT TTGTAAAATTTTGGAGAAGGGAAGTCGGAACACAAGGAAGGACCGCTCACCCGCGGACTC AGGGCTCGCGGCGGGACTCCAGGACCCTGGGTCCAGCATGGAGGTGGTGGACCCGCAGCA GCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTGGGTATGAACACGTTCATCCACCG CATCGACTCCACCCGAGTCATCTACCAGCCGCGCCCGCAGCGGGCCAAGCTCATCTGCAA GTACCTGATGGGGGACCTGCTGGGTGGAAGGCTCTTACNGCAAGTGAANGGAGGTGCTGG AACTCCGANACACTGTGCAGGAAGGGCCGTCAGATCCTCAGAAAAAANAAATTGCCAAGA TCCCCACCGGGGAGGCAACGTGG >OriGene 3' read for NM_000455 unedited
CTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTAAAACCCACCTTTTATTTTTTTTTAAAAAAAAAAAAAAAAAAAAA AATTGGACCCAACCAAACAAAAAACCAAAGCGGCCGCCCGGTTTCCAGGGGGCCCTGCAT GCATGGGGGGGTCAGGACCCTGGTCTCCACACCCGCCAGTTGGTTTGCGGGGGGGCCCCC GAACGGCCCTGGGCCCCCTGCGGACCACAAGGCCACGGGCGGGGCCAGTATTCTCCACAT AAAGGGCATGGAGGCCGCTTCCTTCTTCCCACGCCCGCCCGGAAAGGCTCCCCCCGGGGC TGCAAAGTAAACAACCCGCGTGCACTGCCGGGCGGCCAAGGGGGGAGGGCTGCCCCCGGT CCCTGTTGTCCCCCTGCCCGGCCCTGAAGGGCCCTCCGGAGGTCCTGGGGCGTGGCCGGC ACAAAACCATGGCGGCCACCTCTCCGGGAGGGCGGGCGGAACCGGCAGAAAAACTGAGGG CCTGGCCCGGCCACCTGGCGGGGCTCCTGAACACGGGCTGAAGGCGGCCACCCTCACTGT TGTTTGCAGGCCAACAGCCGGCGGATCTTGCTGCTGGCGGACCAGGCCTTGCGGGCAGGG TTGGGGGCCCGGCCCTCCGCCCTGAATTTGGTGCTCAGCTGCGCCGCCTCTGTGCCGTTC ATACACACGGCCTTGGGGAGGCCCCGGCGCTGTACATTGAGACTGGCCTCCTCTTNTGGG ACCTGTCCGGGCACCGTGAAGTCCTGAGTGTAAATGATGTCATCCTCCATGTCAAAGAGT CCTGGTCCTCGTCCGCCCGTGCAGGTCCTCCAGTACGNCACACATTATGCTGCGCACCGT CCTTGNGTTTGGCCTCGG |
Restriction Sites | NotI-NotI |
ACCN | NM_000455 |
Insert Size | 2440 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000455.4, NP_000446.1 |
RefSeq Size | 3286 bp |
RefSeq ORF | 1302 bp |
Locus ID | 6794 |
Cytogenetics | 19p13.3 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Adipocytokine signaling pathway, mTOR signaling pathway |
Gene Summary | 'This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC323432 | STK11 (untagged)-Kinase deficient mutant (K78M) of Human serine/threonine kinase 11 (STK11) |
USD 760.00 |
|
RC202885 | STK11 (Myc-DDK-tagged)-Human serine/threonine kinase 11 (STK11) |
USD 420.00 |
|
RG202885 | STK11 (GFP-tagged) - Human serine/threonine kinase 11 (STK11) |
USD 460.00 |
|
RC202885L1 | Lenti ORF clone of Human serine/threonine kinase 11 (STK11), Myc-DDK-tagged |
USD 620.00 |
|
RC202885L2 | Lenti ORF clone of Human serine/threonine kinase 11 (STK11), mGFP tagged |
USD 768.00 |
|
RC202885L3 | Lenti ORF clone of Human serine/threonine kinase 11 (STK11), Myc-DDK-tagged |
USD 620.00 |
|
RC202885L4 | Lenti ORF clone of Human serine/threonine kinase 11 (STK11), mGFP tagged |
USD 768.00 |
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