LKB1 (STK11) (NM_000455) Human Untagged Clone

CAT#: SC119871

STK11 (untagged)-Human serine/threonine kinase 11 (STK11)


  "NM_000455" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol STK11
Synonyms hLKB1; LKB1; PJS
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_000455 edited
ATGGAGGTGGTGGACCCGCAGCAGCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTG
GGTATGGACACGTTCATCCACCGCATCGACTCCACCGAGGTCATCTACCAGCCGCGCCGC
AAGCGGGCCAAGCTCATCGGCAAGTACCTGATGGGGGACCTGCTGGGGGAAGGCTCTTAC
GGCAAGGTGAAGGAGGTGCTGGACTCGGAGACGCTGTGCAGGAGGGCCGTCAAGATCCTC
AAGAAGAAGAAGTTGCGAAGGATCCCCAACGGGGAGGCCAACGTGAAGAAGGAAATTCAA
CTACTGAGGAGGTTACGGCACAAAAATGTCATCCAGCTGGTGGATGTGTTATACAACGAA
GAGAAGCAGAAAATGTATATGGTGATGGAGTACTGCGTGTGTGGCATGCAGGAAATGCTG
GACAGCGTGCCGGAGAAGCGTTTCCCAGTGTGCCAGGCCCACGGGTACTTCTGTCAGCTG
ATTGACGGCCTGGAGTACCTGCATAGCCAGGGCATTGTGCACAAGGACATCAAGCCGGGG
AACCTGCTGCTCACCACCGGTGGCACCCTCAAAATCTCCGACCTGGGCGTGGCCGAGGCA
CTGCACCCGTTCGCGGCGGACGACACCTGCCGGACCAGCCAGGGCTCCCCGGCTTTCCAG
CCGCCCGAGATTGCCAACGGCCTGGACACCTTCTCCGGCTTCAAGGTGGACATCTGGTCG
GCTGGGGTCACCCTCTACAACATCACCACGGGTCTGTACCCCTTCGAAGGGGACAACATC
TACAAGTTGTTTGAGAACATCGGGAAGGGGAGCTACGCCATCCCGGGCGACTGTGGCCCC
CCGCTCTCTGACCTGCTGAAAGGGATGCTTGAGTACGAACCGGCCAAGAGGTTCTCCATC
CGGCAGATCCGGCAGCACAGCTGGTTCCGGAAGAAACATCCTCCGGCTGAAGCACCAGTG
CCCATCCCACCGAGCCCAGACACCAAGGACCGGTGGCGCAGCATGACTGTGGTGCCGTAC
TTGGAGGACCTGCACGGCGCGGACGAGGACGAGGACCTCTTCGACATCGAGGATGACATC
ATCTACACTCAGGACTTCACGGTGCCCGGACAGGTCCCAGAAGAGGAGGCCAGTCACAAT
GGACAGCGCCGGGGCCTCCCCAAGGCCGTGTGTATGAACGGCACAGAGGCGGCGCAGCTG
AGCACCAAATCCAGGGCGGAGGGCCGGGCCCCCAACCCTGCCCGCAAGGCCTGCTCCGCC
AGCAGCAAGATCCGCCGGCTGTCGGCCTGCAAGCAGCAGTGA
>OriGene 5' read for NM_000455 unedited
CATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCGGACGCC
CCCAGCCCCCCGAACGCTCGCCCGGGCCGGCGGGAGTCGGCGCCCCCCGGGAGGTCCGCT
CGGTCGTCCGCGGCGGAGCGTTTGCTCCTGGGACAGGCGGTGGGACCGGGGCGTCGCCGG
AGACGCCCCCAGCGAAGTTGGGCTCTCCAGGTGTGGGGGTCCCGGGGGGTAGCGACGTCG
CGGACCCGGCCTGTGGGATGGGCGGCCCGGAGAAGACTGCGCTCGGCCGTGTTCATACTT
GTCCGTGGGCCTGAGGTCCCCGGAGGATGACCTAGCACTGAAAAGCCCCGGCCGGCCTCC
CCAGGGTCCCCGAGGACGAAGTTGACCCTGACCGGGCCGTCTCCCAGTTCTGAGGCCCGG
GTCCCACTGGAACTCGCGTCTGAGCCGCCGTCCCGGACCCCCGGTGCCCGCCGGTCCGCA
GACCCTGCACCGGGCTTGGACTCGCAGCCGGGACTGACGTGTAGAACAATCGTTTCTGTT
GGAAGAAGGGTTTTTCCCTTCCTTTTGGGGTTTTTGTTGCCTTTTTTTTTTCTTTTTTCT
TTGTAAAATTTTGGAGAAGGGAAGTCGGAACACAAGGAAGGACCGCTCACCCGCGGACTC
AGGGCTCGCGGCGGGACTCCAGGACCCTGGGTCCAGCATGGAGGTGGTGGACCCGCAGCA
GCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTGGGTATGAACACGTTCATCCACCG
CATCGACTCCACCCGAGTCATCTACCAGCCGCGCCCGCAGCGGGCCAAGCTCATCTGCAA
GTACCTGATGGGGGACCTGCTGGGTGGAAGGCTCTTACNGCAAGTGAANGGAGGTGCTGG
AACTCCGANACACTGTGCAGGAAGGGCCGTCAGATCCTCAGAAAAAANAAATTGCCAAGA
TCCCCACCGGGGAGGCAACGTGG
>OriGene 3' read for NM_000455 unedited
CTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTAAAACCCACCTTTTATTTTTTTTTAAAAAAAAAAAAAAAAAAAAA
AATTGGACCCAACCAAACAAAAAACCAAAGCGGCCGCCCGGTTTCCAGGGGGCCCTGCAT
GCATGGGGGGGTCAGGACCCTGGTCTCCACACCCGCCAGTTGGTTTGCGGGGGGGCCCCC
GAACGGCCCTGGGCCCCCTGCGGACCACAAGGCCACGGGCGGGGCCAGTATTCTCCACAT
AAAGGGCATGGAGGCCGCTTCCTTCTTCCCACGCCCGCCCGGAAAGGCTCCCCCCGGGGC
TGCAAAGTAAACAACCCGCGTGCACTGCCGGGCGGCCAAGGGGGGAGGGCTGCCCCCGGT
CCCTGTTGTCCCCCTGCCCGGCCCTGAAGGGCCCTCCGGAGGTCCTGGGGCGTGGCCGGC
ACAAAACCATGGCGGCCACCTCTCCGGGAGGGCGGGCGGAACCGGCAGAAAAACTGAGGG
CCTGGCCCGGCCACCTGGCGGGGCTCCTGAACACGGGCTGAAGGCGGCCACCCTCACTGT
TGTTTGCAGGCCAACAGCCGGCGGATCTTGCTGCTGGCGGACCAGGCCTTGCGGGCAGGG
TTGGGGGCCCGGCCCTCCGCCCTGAATTTGGTGCTCAGCTGCGCCGCCTCTGTGCCGTTC
ATACACACGGCCTTGGGGAGGCCCCGGCGCTGTACATTGAGACTGGCCTCCTCTTNTGGG
ACCTGTCCGGGCACCGTGAAGTCCTGAGTGTAAATGATGTCATCCTCCATGTCAAAGAGT
CCTGGTCCTCGTCCGCCCGTGCAGGTCCTCCAGTACGNCACACATTATGCTGCGCACCGT
CCTTGNGTTTGGCCTCGG
Restriction Sites NotI-NotI     
ACCN NM_000455
Insert Size 2440 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000455.4, NP_000446.1
RefSeq Size 3286 bp
RefSeq ORF 1302 bp
Locus ID 6794
Cytogenetics 19p13.3
Domains pkinase, TyrKc, S_TKc
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Adipocytokine signaling pathway, mTOR signaling pathway
Gene Summary 'This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.