IFNGR1 (NM_000416) Human Untagged Clone

CAT#: SC119876

IFNGR1 (untagged)-Human interferon gamma receptor 1 (IFNGR1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNGR1
• Synonyms: CD119; IFNGR; IMD27A; IMD27B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119876 sequence for NM_000416 edited (data generated by NextGen Sequencing)
  ATGGCTCTCCTCTTTCTCCTACCCCTTGTCATGCAGGGTGTGAGCAGGGCTGAGATGGGC
  ACCGCGGATCTGGGGCCGTCCTCAGTGCCTACACCAACTAATGTTACAATTGAATCCTAT
  AACATGAACCCTATCGTATATTGGGAGTACCAGATCATGCCACAGGTCCCTGTTTTTACC
  GTAGAGGTAAAGAACTATGGTGTTAAGAATTCAGAATGGATTGATGCCTGCATCAATATT
  TCTCATCATTATTGTAATATTTCTGATCATGTTGGTGATCCATCAAATTCTCTTTGGGTC
  AGAGTTAAAGCCAGGGTTGGACAAAAAGAATCTGCCTATGCAAAGTCAGAAGAATTTGCT
  GTATGCCGAGATGGAAAAATTGGACCACCTAAACTGGATATCAGAAAGGAGGAGAAGCAA
  ATCATGATTGACATATTTCACCCTTCAGTTTTTGTAAATGGAGACGAGCAGGAAGTCGAT
  TATGATCCCGAAACTACCTGTTACATTAGGGTGTACAATGTGTATGTGAGAATGAACGGA
  AGTGAGATCCAGTATAAAATACTCACGCAGAAGGAAGATGATTGTGACGAGATTCAGTGC
  CAGTTAGCGATTCCAGTATCCTCACTGAATTCTCAGTACTGTGTTTCAGCAGAAGGAGTC
  TTACATGTGTGGGGTGTTACAACTGAAAAGTCAAAAGAAGTTTGTATTACCATTTTCAAT
  AGCAGTATAAAAGGTTCTCTTTGGATTCCAGTTGTTGCTGCTTTACTACTCTTTCTAGTG
  CTTAGCCTGGTATTCATCTGTTTTTATATTAAGAAAATTAATCCATTGAAGGAAAAAAGC
  ATAATATTACCCAAGTCCTTGATCTCTGTGGTAAGAAGTGCTACTTTAGAGACAAAACCT
  GAATCAAAATATGTATCACTCATCACGTCATACCAGCCATTTTCCTTAGAAAAGGAGGTG
  GTCTGTGAAGAGCCGTTGTCTCCAGCAACAGTTCCAGGCATGCATACCGAAGACAATCCA
  GGAAAAGTGGAACATACAGAAGAACTTTCTAGTATAACAGAAGTGGTGACTACTGAAGAA
  AATATTCCTGACGTGGTCCCGGGCAGCCATCTGACTCCAATAGAGAGAGAGAGTTCTTCA
  CCTTTAAGTAGTAACCAGTCTGAACCTGGCAGCATCGCTTTAAACTCGTATCACTCCAGA
  AATTGTTCTGAGAGTGATCACTCCAGAAATGGTTTTGATACTGATTCCAGCTGTCTGGAA
  TCACATAGCTCCTTATCTGACTCAGAATTTCCCCCAAATAATAAAGGTGAAATAAAAACA
  GAAGGACAAGAGCTCATAACCGTAATAAAAGCCCCCACCTCCTTTGGTTATGATAAACCA
  CATGTGCTAGTGGATCTACTTGTGGATGATAGCGGTAAAGAGTCCTTGATTGGTTATAGA
  CCAACAGAAGATTCCAAAGAATTTTCATGA
  
  Clone variation with respect to NM_000416.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000416 unedited
  TCAAAATTTGTATACCATCATATAGGGCGGCCGCGAATTCGCACGAGGCCTCGTGCCGAA
  TTCGGCACGAGGCCAGCGACCGTCGGTAGCAGCATGGCTCTCCTCTTTCTCCTACCCCTT
  GTCATGCAGGGTGTGAGCAGGGCTGAGATGGGCACCGCGGATCTGGGGCCGTCCTCAGTG
  CCTACACCAACTAATGTTACAATTGAATCCTATAACATGAACCCTATCGTATATTGGGAG
  TACCAGATCATGCCACAGGTCCCTGTTTTTACCGTAGAGGTAAAGAACTATGGTGTTAAG
  AATTCAGAATGGATTGATGCCTGCATCAATATTTCTCATCATTATTGTAATATTTCTGAT
  CATGTTGGTGATCCATCAAATTCTCTTTGGGTCAGAGTTAAAGCCAGGGTTGGACAAAAA
  GAATCTGCCTATGCAAAGTCAGAAGAATTTGCTGTATGCCGAGATGGAAAAATTGGACCA
  CCTAAACTGGATATCAGAAAGGAGGAGAAGCANATCATGATTGACATATTTCACCCTTCA
  GTTTTTGTAAATGGAGACGAGCAGGAAGTCGATTATGATCCCGAAACTACCTGTTACATT
  ANGGTGTACAATGTGTATGTGAGAATGAACGGAAGTGAGATCCAGTANTAAATACTCACG
  CAGAAGGAAGATGATTGTGACGAGATTCAGTGCCAGTTAGCGATTCCAGTATCCTCACTG
  AATTCTCAGTACTGTNNGTTCAGCAGAAGAGTCCTACATGTGTGGGGGTGGTACCCACTG
  AAAGTCAAAAGAGTTTGTTTAACATTTTTCATAGCAGTATAAAAGGTCTCCTTGGATCCC
  AGTGTTGCTGCCTTACCACTCTTCCTAGGGCTTAACCTGGATTCCATCTGTTTATTTTAA
  GGAAAATTNATCCTTTGNAGGAAAAAGCCTATTTTTCCCCAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000416 unedited
  GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGTTTTAAAATTCTTTATTTA
  AAAATCTCTAACTGTAATGTTTCATAAAAAATATACACGTTTCTATTTACATATTCCATT
  AATTCTATTAGTTTGAATTAGATTTTAAGTCCAATTTTGAAAAGCTTGCAGAATTTCTTC
  TGAAATTACTTAAAATTACTGTATGCATAAACTTACAAAAACATATGCTATACCAAGGCA
  GAGAAAAGAAAAAAAGTGAAGTGGCTACAAAGGTCCCTGGGGCATCACCTGCTCACCTAG
  GAACCAGGAGTACTGGATACTGTTCCGTTACTGGTAACCTATCTGGATGTAAAGGTTCAT
  AAGTTACAATGCTTTTTTTGTTTAAAAAAAAAAAAAAGTCTGTACTTTACAAGCCAAAAG
  TGAAAATGCCACACATCCTCTTTACGCTTTCATGTACACTAAGTCACTCCATTTGGTTGA
  TACCAACTAAGATACAATTTCTGAGATCATAATCTTTTCATGAAATTAAAGCAGAAAACT
  GTCCAGGAAAATCAGACTTCAAAGTTGGTGCAACTTAGCTGATCTCATGAAAATTCTTTG
  GAATCTTCTGTTGGTCTATAACCAATCAAGGACTCTTTACCGCTATCATCCACAAGTAGA
  TCCACTAGCACATGTGGTTTATCATAACCAAAGGAGGTGGGGGGCTTTTATTACGGTTAT
  GAGCTCTTGTCCTTTCTGTTTTATTTCACCTTTTTATTTGGGGGAAATTCTGAGTCAGAT
  AAGAGCTATGTGATTCAGACAGCTGGATCAGTATCAAACCATTTCTGAGTGATCACTCTA
  NACCATTCTGGAGGATACCAGTTTAAGCGAGCTCCAGGTCAAATGGTACACTTAAGGGAA
  AACTTCTTTTTTTTGAGTCAAAGCTGCCCGGACCCTCAGAATATTCTTAAAATACCACTT
  GGTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000416
• Insert Size: 2140 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000416.1, NP_000407.1
• RefSeq Size: 2059 bp
• RefSeq ORF: 1470 bp
• Locus ID: 3459
• Cytogenetics: 6q23.3
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity
• Gene Summary: 'This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).