SCNN1B (NM_000336) Human Untagged Clone

CAT#: SC119979

SCNN1B (untagged)-Human sodium channel, nonvoltage-gated 1, beta (SCNN1B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCNN1B
• Synonyms: BESC1; ENaCb; ENaCbeta; LIDLS1; SCNEB
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000336 edited
  CGGCACGAGGCGCATCCTCCGTGTCCCCGCTCCGCCGCCCGAGCAGGTGCCACTATGCAC
  GTGAAGAAGTACCTGCTGAAGGGCCTGCATCGGCTGCAGAAGGGCCCCGGCTACACGTAC
  AAGGAGCTGCTGGTGTGGTACTGCGACAACACCAACACCCACGGCCCCAAGCGCATCATC
  TGTGAGGGGCCCAAGAAGAAAGCCATGTGGTTCCTGCTCACCCTGCTCTTCGCCGCCCTC
  GTCTGCTGGCAGTGGGGCATCTTCATCAGGACCTACTTGAGCTGGGAGGTCAGCGTCTCC
  CTCTCCGTAGGCTTCAAGACCATGGACTTCCCCGCCGTCACCATCTGCAATGCTAGCCCC
  TTCAAGTATTCCAAAATCAAGCATTTGCTGAAGGACCTGGATGAGCTGATGGAAGCTGTC
  CTGGAGAGAATCCTGGCTCCTGAGCTAAGCCATGCCAATGCCACCAGGAACCTGAACTTC
  TCCATCTGGAACCACACACCCCTGGTCCTTATTGATGAACGGAACCCCCACCACCCCATG
  GTCCTTGATCTCTTTGGAGACAACCACAATGGCTTAACAAGCAGCTCAGCATCAGAAAAG
  ATCTGTAATGCCCACGGGTGCAAAATGGCCATGAGACTATGTAGCCTCAACAGGACCCAG
  TGTACCTTCCGGAACTTCACCAGTGCTACCCAGGCATTGACAGAGTGGTACATCCTGCAG
  GCCACCAACATCTTTGCACAGGTGCCACAGCAGGAGCTAGTAGAGATGAGCTACCCCGGC
  GAGCAGATGATCCTGGCCTGCCTATTCGGAGCTGAGCCCTGCAACTACCGGAACTTCACG
  TCCATCTTCTACCCTCACTATGGCAACTGTTACATCTTCAACTGGGGCATGACAGAGAAG
  GCACTTCCTTCGGCCAACCCTGGAACTGAATTCGGCCTGAAGTTGATCCTGGACATAGGC
  CAGGAAGACTACGTCCCCTTCCTTGCGTCCACGGCCGGGGTCAGGCTGATGCTTCACGAG
  CAGAGGTCATACCCCTTCATCAGAGATGAGGGCATCTACGCCATGTCGGGGACAGAGACG
  TCCATCGGGGTACTCGTGGACAAGCTTCAGCGCATGGGGGAGCCCTACAGCCCGTGCACC
  GTGAATGGTTCTGAGGTCCCCGTCCAAAACTTCTACAGTGACTACAACACGACCTACTCC
  ATCCAGGCCTGTCTTCGCTCCTGCTTCCAAGACCACATGATCCGTAACTGCAACTGTGGC
  CACTACCTGTACCCACTGCCCCGTGGGGAGAAATACTGCAACAACCGGGACTTCCCAGAC
  TGGGCCCATTGCTACTCAGATCTACAGATGAGCGTGGCGCAGAGAGAGACCTGCATTGGC
  ATGTGCAAGGAGTCCTGCAATGACACCCAGTACAAGATGACCATCTCCATGGCTGACTGG
  CCTTCTGAGGCCTCCGAGGACTGGATTTTCCACGTCTTGTCTCAGGAGCGGGACCAAAGC
  ACCAATATCACCCTGAGCAGGAAGGGAATTGTCAAGCTCAACATCTACTTCCAAGAATTT
  AACTATCGCACCATTGAAGAATCAGCAGCCAATAACATCGTCTGGCTGCTCTCGAATCTG
  GGTGGCCAGTTTGGCTTCTGGATGGGGGGCTCTGTGCTGTGCCTCATCGAGTTTGGGGAG
  ATCATCATCGACTTTGTGTGGATCACCATCATCAAGCTGGTGGCCTTGGCCAAGAGCCTA
  CGGCAGCGGCGAGCCCAAGCCAGCTACGCTGGCCCACCGCCCACCGTGGCCGAGCTGGTG
  GAGGCCCACACCAACTTTGGCTTCCAGCCTGACACGGCCCCCCGCAGCCCCAACACTGGG
  CCCTACCCCAGTGAGCAGGCCCTGCCCATCCCAGGCACCCCGCCCCCCAACTATGACTCC
  CTGCGTCTGCAGCCGCTGGACGTCATCGAGTCTGACAGTGAGGGTGATGCCATCTAACCC
  TGCCCCTGCCCACCCCGGGCGGCTGAAACTCACTGAGCAGCCAAGACTGTTGCCCGAGGC
  CTCACTGTATGGTGCCCTCTCCAAAGGGTCGGGAGGGTAGCTCTCCAGGCCAGAGCTTGT
  GTCCTTCAACAGAGAGGCCAGCGGCAACTGGTCCGTTACTGGCCAAGGGCTCTGTAGAAT
  CACGGTGCTGGTACAGGATGCAGGAATAAATTGTATCTTCACCTGGTTCCTACCCTCGTC
  CCTACCTGTCCTGATCCTGGTCCTGAAGACCCCTCGGAACACCCTCTCCTGGTGGCAGGC
  CACTTCCCTCCCAGTGCCAGTCTCCATCCACCCCAGAGAGGAACAGGCGGGTGGGCCATG
  TGGTTTTCTCCTTCCTGGCCTTGGCTGGCCTCTGGGGCAGGGGTGGTGGAGAGATGGAAG
  GGCATCAGGTGTAGGGACCCTGCCAAGTGGCACCTGATTTACTCTAGAAAATAAAAGTAG
  AAAAT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000336 unedited
  NGGGATTTCAGGATATTTGTNAATCCGNACTTTACTNTNAGGGNCGGCACGCGCAATTCG
  GCACGAGGCGCATCCTCCGTGTCCCCGCTCCGCCGCCCGAGCAGGTGCCACTATGCACGT
  GAAGAATACCTGCTGAAGGGCCTGCATCGGCTGCAGAAGGGCCCCGGCTACACGTACAAG
  GAGCTGCTGGTGTGGTACTGCGACAACACCAACACCCACGGCCCCAAGCGCATCATCTGT
  GAGGGGCCCAAGAAGAAAGCCATGTGGTTCCTGCTCACCCTGCTCTTCGCCGCCCTCGTC
  TGCTGGCAGTGGGGCATCTTCATCAGGACCTACTTGAGCTGGGAGGTCAGCGTCTCCCTC
  TCCGTAGGCTTCAAGACCATGGACTTCCCCGCCGTCACCATCTGCAATGCTAGCCCCTTC
  AAGTATTCCAAAATCAAGCATTTGCTGAAGGACCTGGATGAGCTGATGGAAGCTGTCCTG
  GAGAGAATCCTGGCTCCTGAGCTAAGCCATGCCAATGCCACCAGGAACCTGAACTTCTCC
  ATCTGGAACCACACACCCCTGGTCCTTATTGATGAACGGAACCCCCACCACCCCATGGTC
  CTTGATCTCTTTGGAGACAACCACAATGGCTTAACAAGCAGCTCAGCATCAGAAAAGATC
  TGNTATGCCCACGGGTGCAAAATGGCCATGAGACTATGTAGCCTCAACAGGACCCAGTGT
  ACCTTCCGGAACTTCACCAGTGCTACCCCAGCATTGACAGAGTGGTACATCCTGCNAGCC
  ACCAACATCTTTGCACAGGTGCCACAGCANGAGCTAGTAGAGATGAGCTACCCCGGCCAG
  CAGATGATCCTGGCCTGCCTATTCGGAACTGAGCCTGNAACTACCGGAACTTACGTCCAT
  TTNCTACCCTTACTAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000336 unedited
  AAAAAAACCTACTAGTACCGCGCCGCGTGCNATGATCGATTTTTTTTTTTTTTTTTTCAT
  ATTTTCTACTTTTATTTTCTAGAGTAAATCAGGTGCCACTTGGCAGGGTCCCTACACCTG
  ATGCCCTTCCATCTCTCCACCACCCCTGCCCCAGAGGCCAGCCAAGGCCAGGAAGGAGAA
  AACCACATGGCCCACCCGCCTGTTCCTCTCTGGGGTGGATGGAGACTGGCACTGGGAGGG
  AAGTGGCCTGCCACCAGGAGAGGGTGTTCCGAGGGGTCTTCAGGACCAGGATCAGGACAG
  GTAGGGACGAGGGTAGGAACCAGGTGAAGATACAATTTATTCCTGCATCCTGTACCAGCA
  CCGTGATTCTACAGAGCCCTTGGCCAGTAACGGACCAGTTGCCGCTGGCCTCTCTGTTGA
  AGGACACAAGCTCTGGCCTGGAGAGCTACCCTCCCGACCCTTTGGAGAGGGCACCATACA
  GTGAGGCCTCGGGCAACAGTCTTGGCTGCTCAGTGAGTTTCAGCCGCCCGGGGTGGGCAG
  GGGCAGGGTTAGATGGCATCACCCTCACTGTCAGACTCGATGACGTCCAGCGGCTGCAGA
  CGCAGGGAGTCATATTTGGGGGGCGGGGTGCCTGGGATGGGCAGGGCCTGCTCACTGGGG
  TAGGGCCCAGTGTTGGGGCTGCGGGGGGCCGTGTCANGCTGGAAGCCAAAGTTGGTGTGG
  GCCTCCACCAGCTCGGCCACGGTGGGCGGTGGGCCAGCGTAGCTGGCTTGGGCTCGCCGC
  TGCCGTTAGCTCTTGGCCAAGCCACCAGCTTGATGATGGTGATCCACACAAAGTCCATGA
  TGATCTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000336
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000336.1, NP_000327.1
• RefSeq Size: 2564 bp
• RefSeq ORF: 1923 bp
• Locus ID: 6338
• Cytogenetics: 16p12.2
• Domains: ASC
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Protein Pathways: Taste transduction
• Gene Summary: 'Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]'