NOSTRIN (NM_052946) Human Untagged Clone

CAT#: SC120170

NOSTRIN (untagged)-Human nitric oxide synthase trafficker (NOSTRIN), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOSTRIN
• Synonyms: DaIP2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120170 sequence for NM_052946 edited (data generated by NextGen Sequencing)
  ATGAAATCCACAGCGGACCTGCATCAAAAACTTGGCAAAGCAATTGAATTGGAAGCAATA
  AAACCGACTTATCAAGTCCTAAATGTACAAGAGAAGAAGAGAAAATCACTTGACAATGAA
  GTTGAAAAGACAGCAAATCTTGTCATTAGCAACTGGAATCAGCAAATTAAGGCCAAGAAG
  AAATTAATGGTTAGTACCAAGAAACATGAAGCACTTTTCCAGCTTGTAGAAAGCTCCAAG
  CAATCTATGACTGAGAAGGAGAAGCGGAAGCTCCTCAATAAACTGACAAAATCAACTGAA
  AAGTTGGAAAAGGAAGATGAAAATTACTACCAAAAAAACATGGCGGGTTATTCTACCAGA
  CTGAAATGGGAAAACACACTAGAGAACTGCTACCAGAGCATTCTGGAGCTGGAGAAGGAA
  AGAATTCAACTTTTATGCAATAACTTAAACCAGTACAGCCAACATATTTCTCTTTTTGGC
  CAAACCCTGACCACATGCCACACGCAGATTCACTGTGCCATCAGCAAGATTGACATTGAA
  AAAGATATCCAGGCTGTAATGGAAGAAACTGCAATTTTATCTACAGAAAACAAATCTGAG
  TTCCTGTTAACGGATTACTTTGAAGAAGATCCTAACAGTGCAATGGATAAAGAGAGACGA
  AAGTCTTTACTAAAACCAAAATTATTGAGACTGCAGAGAGACATTGAAAAAGCCTCAAAA
  GACAAGGAAGGCCTGGAACGAATGCTTAAAACGTACTCCAGCACCTCCTCCTTCTCTGAT
  GCAAAGAGCCAGAAAGACACAGCAGCGTTAATGGATGAGAACAATTTGAAACTAGACCTT
  TTGGAAGCGAACTCCTACAAACTGTCATCAATGTTAGCAGAACTTGAGCAAAGACCTCAA
  CCCAGCCATCCTTGTAGTAATTCCATCTTCAGGTGGAGGGAAAAGGAGCATACTCATAGC
  TATGTGAAAATATCTCGGCCTTTTTTAATGAAGAGATTAGAGAATATTGTGAGCAAGGCA
  TCTTCTGGTGGGCAGAGCAATCCAGGTTCTTCAACTCCAGCCCCTGGTGCAGCCCAGCTC
  AGCAGCAGACTTTGCAAGGCCTTGTATTCTTTTCAAGCCAGGCAAGATGATGAGTTGAAT
  TTGGAAAAGGGTGACATTGTGATTATACACGAGAAAAAAGAAGAAGGATGGTGGTTTGGA
  TCTTTGAATGGGAAAAAAGGCCATTTTCCTGCCGCTTATGTGGAGGAGTTACCTTCAAAT
  GCTGGCAACACAGCTACAAAGGCATAA
  
  Clone variation with respect to NM_052946.3
  1184 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052946 unedited
  NNNTTGTTCACATTTGTAAACGACTCATATAGGCGGCCGCGNAATTCGCACCAGGTATAC
  AAGAACCTAAAGAGTTTTCTCAAAATGGAGAGAATTTCTGCAAACAGGTCACATCTGTTC
  TTCAGCAAAGGGCAAACCTGGAAATTAGCTATGCCAAAGGACTTCAGAAACTGGCAAGCA
  AGCTGAGCAAAGCATTACAGAACACGAGAAAAAGTTGTGTTAGCAGTGCCTGGGCCTGGG
  CCTCAGAGGGAATGAAATCCACAGCGGACCTGCATCAAAAACTTGGCAAAGCAATTGAAT
  TGGAAGCAATAAAACCGACTTATCAAGTCCTAAATGTACAAGAGAAGAAGAGAAAATCAC
  TTGACAATGAAGTTGAAAAGACAGCAAATCTTGTCATTAGCAACTGGAATCAGCAAATTA
  AGGCCAAGAAGAAATTAATGGTTAGTACCAAGAAACATGAAGCACTTTTCCAGCTTGTAG
  AAAGCTCCAAGCAATCTATGACTGAGAAGGAGAAGCGGAAGCTCCTCAATAAACTGACAA
  AATCAACTGAAAAGTTGGAAAAGGAAGATGAAAATTACTACCAAAAAAACATGGCGGGTT
  ATTCTACCAGACTGAAATGGGAAAACACACTAGAGAACTGCTACCAGAGCATTCTGGAGC
  TGGAGAAGGAAAGAATTCAACTTTTATGCAATAACTTANACCAGTACAGCCAACATATTT
  CTCTTTTTGGCCAAACCCTGACCACATGCCACACGCAGATTCACTGTGCCATCAGCAAGA
  TTGACATTGAAAAAGAATCCNAGCTGTAATGGAAGAACTGNCATTTATCTACAGAAAACA
  ATCTGAGTTCCTGTTAAACGGATACTTTGAAGAAGATCCCTACAGTGCATGGGATAAAGA
  AGACGAAAAGTCTTACTAAACAAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_052946 unedited
  TANGATCAGTTTTATTTTTTTTTTTTTTAAAGGTAAGAGCACTTTATTCTCTATTTGAAC
  CACACTGTATTGTTGATTACCGAGTGTGAAGGTAGTATGTTCAGAGTCTTGTTTTATGCC
  TTTGTAGCTGTGTTGCCAGCATTTGAAGGTAACTCCTCCACATAAGCGGCAGGAAAATGG
  CCTTTTTTCCCATTCAAAGATCCAAACCACCATCCTTCTTCTTTTTTCTCGTGTATAATC
  ACAATGTCACCCTTTTCCAAATTCAACTCATCATCTTGCCTGGCTTGAAAAGAATACAAG
  GCCTTGCAAAGTCTGCTGCTGAGCTGGGCTGCACCAGGGGCTGGAGTTGAAGAACCTGGA
  TTGCTCTGCCCACCAGAAGATGCCTTGCTCACAATATTCTCTAATCTCTTCATTAAAAAA
  GGCCGAGATATTTTCACATAGCTATGAGTATGCTCCTTTTCCCTCCACCTGAAGATGGAA
  TTACTACAAGGATGGCTGGGTTGAGGTCTTTGCTCAAGTTCTGCTAACATTGATGACAGT
  TTGTAGGAGTTCGCTTCCAAAAGGTCTAGTTTCAAATTGTTCTCATCCATTAACGCTGCT
  GTGTCTTTCTGGCTCTTTGCATCAAAGAAGGAGGAGGTGCTGGAGTACGTTTTAAGCATT
  CGTTCCAGGCCTTCCTTGTCTTTTGAGGCTTTTTCAATGTCTCTCTGCAGTCTCAATAAT
  TTTGGTTTTAGTAAAGACTTTCGTCTCTCTTTACCATTGCACTGGTTAGATCTTCTTCAA
  AGTAATCCCGTAACAGGGACTCAGATTTGTTTTCTGTAGATAAAATTGCAGTTTCTTCCA
  TAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_052946
• ORF Size: 1287 bp
• Insert Size: 1750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_052946.2, NP_443178.1
• RefSeq Size: 1588
• RefSeq ORF: 1287
• Locus ID: 115677
• Domains: SH3
• Gene Summary: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production. [supplied by OMIM, Apr 2004]
  Transcript Variant: This variant (1) lacks an internal exon in the 5' region, resulting in a downstream AUG start codon, as compared to isoform 2. The resulting isoform (1) has a shorter N-terminus, as compared to isoform 2.