NOSTRIN (NM_052946) Human Untagged Clone

CAT#: SC320459

NOSTRIN (untagged)-Human nitric oxide synthase trafficker (NOSTRIN), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOSTRIN
• Synonyms: DaIP2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_052946.2 CCAGAATGCTGGAGCGTAGGTGAAAGGACAAAAGCCAGACACATTTCAACATGAGGGACC
  CACTGACAGATTGTCCGGGCAAACCTGGAAATTAGCTATGCCAAAGGACTTCAGAAACTG
  GCAAGCAAGCTGAGCAAAGCATTACAGAACACGAGAAAAAGTTGTGTTAGCAGTGCCTGG
  GCCTGGGCCTCAGAGGGAATGAAATCCACAGCGGACCTGCATCAAAAACTTGGCAAAGCA
  ATTGAATTGGAAGCAATAAAACCGACTTATCAAGTCCTAAATGTACAAGAGAAGAAGAGA
  AAATCACTTGACAATGAAGTTGAAAAGACAGCAAATCTTGTCATTAGCAACTGGAATCAG
  CAAATTAAGGCCAAGAAGAAATTAATGGTTAGTACCAAGAAACATGAAGCACTTTTCCAG
  CTTGTAGAAAGCTCCAAGCAATCTATGACTGAGAAGGAGAAGCGGAAGCTCCTCAATAAA
  CTGACAAAATCAACTGAAAAGTTGGAAAAGGAAGATGAAAATTACTACCAAAAAAACATG
  GCGGGTTATTCTACCAGACTGAAATGGGAAAACACACTAGAGAACTGCTACCAGAGCATT
  CTGGAGCTGGAGAAGGAAAGAATTCAACTTTTATGCAATAACTTAAACCAGTACAGCCAA
  CATATTTCTCTTTTTGGCCAAACCCTGACCACATGCCACACGCAGATTCACTGTGCCATC
  AGCAAGATTGACATTGAAAAAGATATCCAGGCTGTAATGGAAGAAACTGCAATTTTATCT
  ACAGAAAACAAATCTGAGTTCCTGTTAACGGATTACTTTGAAGAAGATCCTAACAGTGCA
  ATGGATAAAGAGAGACGAAAGTCTTTACTAAAACCAAAATTATTGAGACTGCAGAGAGAC
  ATTGAAAAAGCCTCAAAAGACAAGGAAGGCCTGGAACGAATGCTTAAAACGTACTCCAGC
  ACCTCCTCCTTCTCTGATGCAAAGAGCCAGAAAGACACAGCAGCGTTAATGGATGAGAAC
  AATTTGAAACTAGACCTTTTGGAAGCGAACTCCTACAAACTGTCATCAATGTTAGCAGAA
  CTTGAGCAAAGACCTCAACCCAGCCATCCTTGTAGTAATTCCATCTTCAGGTGGAGGGAA
  AAGGAGCATACTCATAGCTATGTGAAAATATCTCGGCCTTTTTTAATGAAGAGATTAGAG
  AATATTGTGAGCAAGGCATCTTCTGGTGGGCAGAGCAATCCAGGTTCTTCAACTCCAGCC
  CCTGGTGCAGCCCAGCTCAGCAGCAGACTTTGCAAGGCCTTGTATTCTTTTCAAGCCAGG
  CAAGATGATGAGTTGAATTTGGAAAAGGGTGACATTGTGATTATACACGAGAAAAAAGAA
  GAAGGATGGTGGTTTGGATCTTTGAATGGGAAAAAAGGCCATTTTCCTGCCGCTTATGTG
  GAGGAGTTACCTTCAAATGCTGGCAACACAGCTACAAAGGCATAAAACAAGACTCTGAAC
  ATACTACCTTCACACTCGGTAATCAACAATACAGTGTGGTTCAAATAAGAATAAAGTGCT
  CTTACCTTTAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052946.2 unedited
  GTTCTGTGGCGACTCTGTATTCTTAATTGCTTAGTAGAGATATCGTAGAATAAGAACCGC
  GACTGGATCCGGTACCGAGGTAGTTAGCGGACCGACGCGTTAAGTCGGCCGCGAATTCAG
  ATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAAAACGACGGCCAGTAACTATAACGGTC
  CTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCACGAGGCCAAAATGCTGGAGCGTAGGT
  GAAAGGACAAAAGCCAGACACATTTCAACATGAGGGACCCACTGACAGATTGTCCGGGCA
  AACCTGGAAATTAGCTATGCCAAAGGACTTCAAAAACTGGCAAGCAAGCTGAGCAAAGCA
  TTACAGAACACGAGAAAAAGTTGTGTTAGCAGTGCCTGGGCCTGGGCCTCAGAGGGAATG
  AAATCCACAGCGGACCTGCATCAAAAACTTGGGCAAAGCAATTGAATTGGAAGCAATAAA
  ACCGACTTATCAAGTCCTAAATGTACAAGAGAAGAAGAGAAAAATCACTTGACACTGAAG
  TTGAAAAGACAGCAAATCTTGTCATTAGCAACTGGAATCACAATTAAGGCCAAGAAGAAA
  TTAATGGTTAGTACCCAGAAACATGAAGCACTTTTCCAGCTTGTAGAAAGCCTCCAAGCA
  ATCTATGACTGGACAAGCGAGAAACCGAAGGCTCCTTCAATAAACTGACAAAATCAACTG
  AAAAGTTGGAAAAGGAAGATGAAAATTACCTACCCAAAAACAACATGGCGGGTTATTTCT
  ACAGACTGGAATGGGAAAACACACTATAAAACCTGCTACCAGAGTCATTTCTGGAGCTGG
  AGAAGGAAAGATTCAACTTTTATGGCATAACCTTATACCGCTCAGCCGACATATTTCCTC
  TTTTTGGCCAACCCCTGGACCACATGTGCCCTACCGCCAGAATTACTGGTGCGCCACTCG
  CCCAAGAATGTGCATCTATGGAGACGATTACTGT
• Restriction Sites: Please inquire
• ACCN: NM_052946
• ORF Size: 1287 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_052946.2, NP_443178.1
• RefSeq Size: 1588
• RefSeq ORF: 1287
• Locus ID: 115677
• Domains: SH3
• Gene Summary: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production. [supplied by OMIM, Apr 2004]
  Transcript Variant: This variant (1) lacks an internal exon in the 5' region, resulting in a downstream AUG start codon, as compared to isoform 2. The resulting isoform (1) has a shorter N-terminus, as compared to isoform 2.