FKBP2 (NM_057092) Human Untagged Clone

CAT#: SC120228

FKBP2 (untagged)-Human FK506 binding protein 2, 13kDa (FKBP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FKBP2
• Synonyms: FKBP-13; FKBP13; PPIase
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120228 sequence for NM_057092 edited (data generated by NextGen Sequencing)
  ATGAGGCTGAGCTGGTTCCGGGTCCTGACAGTACTGTCCATCTGCCTGAGCGCCGTGGCC
  ACGGCCACGGGGGCCGAGGGCAAAAGGAAGCTGCAGATCGGGGTCAAGAAGCGGGTGGAC
  CACTGTCCCATCAAATCGCGCAAAGGGGATGTCCTGCACATGCACTACACGGGGAAGCTG
  GAAGATGGGACAGAGTTTGACAGCAGCCTGCCCCAGAACCAGCCCTTTGTCTTCTCCCTT
  GGCACAGGCCAGGTCATCAAGGGCTGGGACCAGGGGCTGCTGGGGATGTGTGAGGGGGAA
  AAGCGCAAGCTGGTGATCCCATCCGAGCTAGGGTATGGAGAGCGGGGAGCTCCCCCAAAG
  ATTCCAGGCGGTGCAACCCTGGTGTTCGAGGTGGAGCTGCTCAAAATAGAGCGACGAACT
  GAGCTGTAA
  
  Clone variation with respect to NM_057092.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_057092 unedited
  GGGGCGCGAATTCGGCACCAGGAGACATGAGGCTGAGCTGGTTCCGGGTCCTGACAGTAC
  TGTCCATCTGCCTGAGCGCCGTGGCCACGGCCACGGGGGCCGAGGGCAAAAGGAAGCTGC
  AGATCGGGGTCAAGAAGCGGGTGGACCACTGTCCCATCAAATCGCGCAAAGGGGATGTCC
  TGCACATGCACTACACGGGGAAGCTGGAAGATGGGACAGAGTTTGACAGCAGCCTGCCCC
  AGAACCAGCCCTTTGTCTTCTCCCTTGGCACAGGCCAGGTCATCAAGGGCTGGGACCANG
  GGCTGCTGGGGATGTGTGAGGGGGAAAAGCGCAAGCTGGTGATCCCATCCGAGCTAGGGT
  ATGGAGAGCGGGGAGCTCCCCCAAAGATTCCAGGCGGTGCAACCCTGGTGTTCGAGGTGG
  AGCTGCTCAAAATAGAGCGACGAACTGAGCTGTAACCAGACTGGGGAGGGGCAGGGGGAG
  AGGCCCCCATCAGGGACCAGACTGTTCCAAAAAAAAAACAAAAACAAAAACAACAAAAAA
  ACACTTAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGNCGCGGCATAGCTGGTTCT
  GAACAATCCCCGGTGGGATNCCTGTGACCCCTCCCAGTGCCTCTCTGGCCCTGGAAGGTG
  CACTCCAGTGCCACCAGCCTTGGCTATAAAATTAAGTGATCATTTGCGACTAGGTGCTCT
  ATTGGGGGGGGGGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_057092 unedited
  ACCCCCCCCACCAAAAAAAANAACCACACCAATCCCACACCNNNANNTTTTGACTTTGNN
  ACCGCGGCCCCGCATTCTNANGATCGAGTTTTTTTTTTTTTTTTTTAATGTTTTTTTGTT
  TGTTTTTGTTTTTTGTTTTTTTTTTTGGAACAGTCTGGTCCCTGATGGGGGCCTCTCCCC
  CTGCCCCTCCCCAGTCTGGTTACAGCTCAGTTCGTCGCTCTATTTTGAGCAGCTCCACCT
  CGAACACCAGGGTTGCACCGCCTGGAATCTTTGGGGGAGCTCCCCGCTCTCCATACCCTA
  GCTCGGATGGGATCACCAGCTTGCGCTTTTCCCCCTCACACATCCCCAGCAGCCCCTGGT
  CCCAGCCCTTGATGACCTGGCCTGTGCCAAGGGAGAAGACAAAGGGCTGGTTCTGGGGCA
  GGCTGCTGTCAAACTCTGTCCCATCTTCCAGCTTCCCCGTGTAGTGCATGTGCAGGACAT
  CCCCTTTGCGCGATTTGATGGGACAGTGGTCCACCCGCTTCTTGACCCCGATCTGCAGCT
  TCCTTTTGCCCTCGGCCCCCGTGGCCGTGGCCACGGCGCTCAGGCAGATGGACAGTACTG
  TCAGGACCCGGAACCAGCTCAGCCTCATGTCTCCTGGTGCCGAATTCCCGGCCGCCCTAT
  AGTGAGTCGTATTACAAAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCTC
  CCACCGTACACGCCTACCGCCCATTTGCGTCACGGGGGTGGGGTTATTACCACATTTTTG
  GAAAGTCCCGGTTGATTTTGGGGCCAAAACCAAACTCCCATTGACCGTCAATGGGGGGTG
  GAAGACTTGGAAAACCCCTGGGAGTAAAACCCGCTTTCCCCTGCCCAATTGGCGTAATTT
  GCCAAACCCTTTTAACCCATGGTAATACCCGATAATTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_057092
• Insert Size: 550 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_057092.1, NP_476433.1
• RefSeq Size: 714 bp
• RefSeq ORF: 429 bp
• Locus ID: 2286
• Cytogenetics: 11q13.1
• Domains: FKBP
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 6 encode the same isoform.