LRPPRC (NM_133259) Human Untagged Clone

CAT#: SC120536

LRPPRC (untagged)-Human leucine-rich PPR-motif containing (LRPPRC)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LRPPRC
• Synonyms: CLONE-23970; GP130; LRP130; LSFC
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120536 sequence for NM_133259 edited (data generated by NextGen Sequencing)
  ATGGCAGCCCTGCTGAGATCCGCGCGTTGGTTGCTGCGTGCCGGGGCGGCCCCGCGCCTC
  CCGCTCTCCCTGCGCCTCCTCCCTGGCGGCCCGGGCCGGCTGCATGCCGCCTCCTATCTG
  CCCGCCGCTCGCGCCGGGCCCGTGGCCGGAGGACTACTGAGCCCAGCCAGGCTGTATGCC
  ATTGCTGCCAAAGAAAAAGATATTCAAGAGGAGTCCACTTTTTCTTCTAGGAAGATTTCC
  AATCAGTTTGATTGGGCTCTAATGAGACTAGATCTTTCTGTTCGAAGAACTGGCCGCATT
  CCAAAGAAGCTTCTACAAAAAGTTTTTAATGATACCTGCCGCTCAGGTGGCCTAGGTGGT
  AGTCATGCCTTGCTTCTACTACGTAGTTGTGGTTCTCTCTTGCCTGAACTAAAGCTTGAA
  GAGAGAACAGAATTTGCTCATAGGATATGGGACACACTTCAGAAATTAGGTGCTGTGTAT
  GATGTGAGTCACTATAATGCTTTACTTAAAGTCTATCTTCAAAATGAATATAAATTCTCA
  CCAACTGATTTCCTGGCAAAAATGGAGGAAGCAAACATTCAACCAAATCGAGTGACATAC
  CAGAGATTGATTGCTTCTTATTGTAATGTAGGAGATATTGAAGGTGCCAGCAAGATTCTT
  GGATTTATGAAAACTAAGGATCTCCCAGTTACAGAGGCAGTATTCAGTGCCCTTGTGACA
  GGGCATGCCAGAGCTGGTGATATGGAGAATGCAGAAAACATTCTCACAGTGATGAGAGAT
  GCCGGAATTGAGCCTGGTCCAGACACATACCTCGCATTATTGAATGCATATGCTGAGAAG
  GGCGACATTGACCATGTTAAGCAGACTCTGGAGAAGGTGGAGAAGTCCGAGCTTCACCTT
  ATGGACCGTGATTTACTGCAAATTATTTTTAGCTTCAGTAAAGCTGGGTATCCTCAGTAT
  GTCTCAGAAATTTTGGAAAAAGTTACATGTGAAAGAAGATATATTCCAGATGCAATGAAC
  CTCATTTTACTTTTAGTCACTGAAAAATTGGAAGATGTAGCGTTGCAGATTTTACTAGCA
  TGCCCCGTATCAAAGGAAGATGGCCCAAGTGTCTTTGGCAGTTTCTTTTTACAACACTGT
  GTGACTATGAATACGCCTGTGGAGAAGCTAACAGACTACTGTAAGAAGTTAAAGGAAGTC
  CAGATGCACTCCTTTCCTCTGCAGTTCACCCTCCATTGTGCTTTACTCGCCAATAAAACT
  GATTTGGCAAAAGCCTTAATGAAGGCTGTGAAGGAGGAAGGTTTTCCTATCAGACCTCAC
  TATTTCTGGCCATTGCTAGTTGGACGTCGGAAGGAAAAAAATGTTCAAGGTATAATTGAA
  ATCCTCAAAGGAATGCAAGAATTGGGAGTACATCCTGATCAGGAAACATATACAGATTAT
  GTGATTCCATGCTTTGATAGTGTAAACTCAGCACGAGCCATTTTGCAGGAAAATGGATGT
  CTGTCTGATAGTGATATGTTTTCTCAAGCTGGATTGAGAAGTGAAGCAGCAAATGGGAAC
  TTAGACTTTGTATTATCATTTTTGAAATCAAATACATTGCCCATCTCGCTGCAGTCTATA
  AGAAGTAGCCTACTGCTAGGCTTCAGGAGGTCTATGAATATAAATCTTTGGAGCGAGATA
  ACAGAATTGTTGTACAAGGATGGACGTTATTGCCAGGAGCCTCGAGGACCGACGGAAGCT
  GTTGGCTATTTTCTTTATAACTTGATTGACAGCATGAGTGACTCAGAGGTACAGGCCAAG
  GAGGAGCATTTGAGACAATACTTCCATCAGCTGGAGAAGATGAATGTAAAAATTCCTGAA
  AATATCTACAGAGGCATTCGTAATCTCCTGGAAAGCTACCATGTTCCTGAATTGATTAAG
  GATGCTCACTTGTTGGTTGAGAGTAAGAATTTAGACTTTCAAAAAACTGTGCAACTTACA
  TCATCTGAATTGGAGTCCACACTTGAAACACTAAAAGCTGAAAATCAACCTATAAGAGAT
  GTCCTAAAGCAACTCATATTAGTGCTTTGTTCAGAAGAGAATATGCAAAAAGCCCTTGAA
  TTGAAAGCAAAATATGAATCCGACATGGTTACTGGTGGCTATGCAGCTTTAATAAATTTA
  TGCTGTCGACATGATAAAGTAGAAGATGCCTTGAACTTGAAAGAAGAATTTGACCGCTTA
  GATTCATCTGCTGTCCTTGACACCGGCAAGTATGTAGGCCTTGTAAGAGTATTGGCAAAG
  CATGGCAAGCTCCAAGATGCTATTAACATTCTGAAGGAGATGAAAGAGAAGGATGTTCTT
  ATCAAAGATACAACAGCCTTGTCCTTTTTCCACATGCTAAATGGCGCAGCTTTAAGAGGT
  GAAATTGAAACAGTAAAACAGTTGCATGAAGCCATCGTGACTCTAGGGTTAGCAGAACCA
  TCCACCAACATAAGTTTCCCGTTGGTCACTGTACACTTGGAAAAGGGCGACCTATCTACT
  GCTCTTGAGGTCGCCATTGACTGCTATGAAAAGTATAAAGTATTACCAAGGATTCATGAT
  GTCTTGTGTAAACTGGTAGAGAAAGGCGAGACTGATCTAATTCAGAAAGCAATGGACTTT
  GTGAGCCAAGAACAAGGTGAAATGGTGATGCTCTATGATCTCTTCTTTGCCTTCCTACAA
  ACAGGAAATTACAAAGAGGCCAAGAAGATCATTGAGACTCCAGGGATTAGAGCTCGATCT
  GCAAGGCTTCAGTGGTTTTGTGACAGATGTGTTGCAAATAATCAGGTTGAAACTCTGGAA
  AAATTAGTGGAGCTGACACAGAAGCTATTTGAATGTGATAGAGACCAGATGTACTACAAT
  CTGCTAAAACTGTATAAAATAAACGGTGACTGGCAAAGAGCTGATGCAGTCTGGAATAAA
  ATCCAAGAAGAAAATGTTATTCCTCGTGAAAAGACATTAAGATTATTAGCAGAAATCCTT
  AGAGAGGGTAACCAGGAAGTTCCGTTTGACGTACCTGAGTTGTGGTATGAAGATGAAAAA
  CATTCCCTGAATTCTTCGTCAGCCTCAACCACAGAACCTGATTTCCAGAAAGATATATTG
  ATTGCCTGCCGATTGAACCAAAAAAAAGGGGCATATGATATTTTCCTGAATGCAAAAGAG
  CAAAACATTGTGTTTAATGCTGAAACCTACAGCAATCTCATTAAATTACTGATGTCAGAA
  GATTATTTTACACAAGCAATGGAAGTGAAAGCATTCGCGGAGACCCACATCAAGGGCTTC
  ACACTGAACGATGCTGCCAACAGCCGCCTCATCATAACGCAAGTTAGGCGGGATTATTTG
  AAAGAGGCTGTGACAACACTGAAAACAGTATTGGATCAGCAGCAGACCCCTTCTAGGTTA
  GCAGTGACCCGTGTCATCCAGGCATTGGCCATGAAGGGTGATGTTGAAAACATAGAAGTA
  GTTCAGAAGATGTTAAATGGACTCGAAGACTCCATTGGACTTTCAAAAATGGTTTTCATC
  AATAACATTGCTTTGGCTCAAATAAAGAATAATAACATAGATGCCGCAATAGAAAACATT
  GAAAATATGCTTACTTCAGAGAATAAAGTCATTGAACCCCAATACTTCGGCTTGGCATAC
  TTATTCAGAAAAGTAATAGAGGAGCAGTTGGAACCAGCAGTTGAAAAGATAAGCATCATG
  GCGGAGAGATTGGCCAATCAGTTTGCAATTTATAAACCTGTCACTGATTTTTTCCTTCAA
  CTTGTGGATGCAGGCAAGGTGGATGATGCCAGAGCTCTCCTACAGAGATGTGGTGCAATT
  GCTGAACAAACCCCGATTTTGTTGTTGTTCCTCCTTAGGAATTCTAGGAAACAAGGAAAG
  GCATCAACTGTGAAATCTGTGTTAGAATTGATTCCTGAATTAAATGAAAAGGAAGAAGCA
  TACAATTCCCTCATGAAAAGCTATGTCTCAGAGAAAGATGTCACATCTGCTAAAGCACTG
  TATGAACATTTGACTGCAAAGAATACAAAATTGGATGATCTGTTTCTAAAGCGTTACGCA
  TCTTTGCTGAAGTATGCTGGAGAGCCTGTCCCTTTCATTGAACCCCCTGAAAGCTTTGAA
  TTTTATGCACAGCAGCTAAGAAAATTGAGGGAAAACTCTTCTTGA
  
  Clone variation with respect to NM_133259.3
  1068 a=>g;2481 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133259 unedited
  NGGTCAAAAATTGTAAACGACTCATATAGGCGGCCGCGAAATCGGCACGAGGCTTCCCGC
  TGCGGGGACGTTCGAGCAATGGCAGCCCTGCTGAGATCCGCGCGTTGGTTGCTGCGTGCC
  GGGGCGGCCCCGCGCCTCCCGCTCTCCCTGCGCCTCCTCCCTGGCGGCCCGGGCCGGCTG
  CATGCCGCCTCCTATCTGCCCGCCGCTCGCGCCGGGCCCGTGGCCGGAGGACTACTGAGC
  CCAGCCAGGCTGTATGCCATTGCTGCCAAAGAAAAAGATATTCAAGAGGAGTCCACTTTT
  TCTTCTAGGAAGATTTCCAATCAGTTTGATTGGGCTCTAATGAGACTAGATCTTTCTGTT
  CGAAGAACTGGCCGCATTCCAAAGAAGCTTCTACAAAAAGTTTTTAATGATACCTGCCGC
  TCAGGTGGCCTAGGTGGTAGTCATGCCTTGCTTCTACTACGTAGTTGTGGTTCTCTCTTG
  CCTGAACTAAAGCTTGAAGAGAGAACAGAATTTGCTCATAGGATATGGGACACACTTCAG
  AAATTAGGTGCTGTGTATGATGTGAGTCACTATAATGCTTTACTTAAAGTCTATCTTCAA
  AATGAATATAAATTCTCACCAACTGATTTCCTGGCAAAAATGGAGGAAGCAAACATTCAA
  CCAAATCGAGTGACATACCAGAGATTGATTGCTTCTTATTGTAATGTANGAGATATTGAA
  GGTGCCAGCAAGATTCTTGGATTTATGAAAACTAAGGATCTCCCAGTTACAGAGGCAGTA
  TTCAGTGCCCTTGTGACAGGGCATGCCAGAGCTGGTGATATGGNAGATGCAGAAACATTC
  TCACAGTGATGAGAGAATGCCGAAATGAGCCTGGTCCAGAACATACCTCGCATTATNGAA
  TGCATATGCTGAGAAGGGNCGACATGACCATGNTAAGCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_133259 unedited
  NTTTAGCTCTGGACCCGCGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTAAAA
  AAAATTTCATTTATTTTTCCCTCAGATTACTTCAAAATACATGTAGACACAGAATCACAA
  ATATATACAAAACAAAGTATCGCCTGGTTATTTCAAGAAGAGTTTTCCCTCAATTTTCTT
  AGCTGCTGTGCATAAAATTCAAAGCTTTCAGGGGGTTCAATGAAAGGGACAGGCTCTCCA
  GCATACTTCAGCAAAGATGCGTAACGCTTTAGAAACAGATCATCCAATTTTGTATTCTTT
  GCAGTCAAATGTTCATACAGTGCTTTAGCAGATGTGACATCTTTCTCTGAGACATAGCTT
  TTCATGAGGGAATTGTATGCTTCTTCCTTTTCATTTAATTCAGGAATCAATTCTAACACA
  GATTTCACAGTTGATGCCTTTCCTTGTTTCCTAGAATTCCTAAGGAGGAACAACAACAAA
  ATCGGGGTTTGTTCAGCAATTGCACCACATCTCTGTAGGAGAGCTCTGGCATCATCCACC
  TTGCCTGCATCCACAAGTTGAAGGAAAAAATCAGTGACAGGTTTATAAATTGCAAACTGA
  TTGGCCAATCTCTCCGCCATGATGCTTATCTTTTCAACTGCTGGTTCCAACTGCTCCTCT
  ATTACTTTTCTGAATAAGTATGCCAAGCCGAAGTATTGGGGTTCAATGACTNTATTCTCT
  GAAGTAAGCATATTTTCAATGTTTTCTATTGCGGCATCTATGNTACTATTCTTTATTTGA
  GCCCAAAGCATGTTATTGATGAAAACCATCTTTGAAAGTCCAATGGNAGTCTCGAGTCCC
  ATTAACATCCTCTGAACTACTTCTATGTTTTCACATCACCCTTCATGCCATGCCTGNATG
  ACACGGTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_133259
• ORF Size: 4185 bp
• Insert Size: 4470
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_133259.2, NP_573566.2
• RefSeq Size: 5095
• RefSeq ORF: 4185
• Locus ID: 10128
• Domains: PPR
• Gene Summary: This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]