ATP dependent metalloprotease YME1L1 (YME1L1) (NM_139312) Human Untagged Clone

CAT#: SC120718

YME1L1 (untagged)-Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: YME1L1
• Synonyms: FTSH; MEG4; OPA11; PAMP; YME1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_139312, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTTTCCTTGTCGAGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCC
  ATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGATGTAGT
  TCCTGAGCATGAGGCTCCCAGCAGTGAGTGTATGTTCAGTGACTTCCTGACGAAGCTTAACATTGTTTCA
  ATTGGCAAAGGAAAAATATTCGAAGGGTACAGATCCATGTTCATGGAGCCAGCAAAAAGGATGAAGAAGA
  GCTTGGACACAACCGATAACTGGCACATCCGTCCAGAACCCTTCTCCCTCTCAATCCCTCCTTCACTTAA
  CTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTCCT
  GGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTTG
  AAAATAAATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAG
  AGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTTTCATACAGTCTCGGGGTTTTAAAACT
  TTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCAT
  CATTCGTGAAGGGGTTTCTTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAAC
  CAAAAATATACCTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGCGGAAGGTTTTCTGAAAGCTCAA
  GCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTCTTCGTTCTGCTGCTATTCG
  GCATTTATGGACTTCTAAAAAACCCATTTTTATCTGTCCGCTTCCGGACAACAACAGGGCTTGATTCTGC
  AGTAGATCCTGTCCAGATGAAAAATGTCACCTTTGAACATGTTAAAGGGGTGGAGGAAGCTAAACAAGAA
  TTACAGGAAGTTGTTGAATTCTTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAAAG
  GAATTCTTTTAGTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGA
  TGTTCCTTTTTATTATGCTTCTGGATCCGAATTTGATGAGATGTTTGTGGGTGTGGGAGCCAGCCGTATC
  AGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATTGATGAATTAGATTCTGTTG
  GTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGGCAGACCATAAATCAACTTCTTGCTGAAAT
  GGATGGTTTTAAACCCAATGAAGGAGTTATCATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAAT
  GCCTTAATACGTCCTGGTCGTTTTGACATGCAAGTTACAGTTCCAAGGCCAGATGTAAAAGGTCGAACAG
  AAATTTTGAAATGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGCTCGAGG
  TACTGTTGGCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCAGCTGTTGAT
  GGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTCCAAAGACAAAATTCTAATGGGGCCTGAAAGAA
  GAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCATATCATGAATCTGGTCATGCCATTATTGC
  ATATTACACAAAAGATGCAATGCCTATCAACAAAGCTACAATCATGCCACGGGGGCCAACACTTGGACAT
  GTGTCCCTGTTACCTGAGAATGACAGATGGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTA
  GTATGGGAGGAAGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGGTGCTTCCAGTGA
  TTTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAGCTTGGAGTT
  ATGACCTACAGTGATACAGGGAAACTAAGTCCAGAAACCCAATCTGCCATCGAACAAGAAATAAGAATCC
  TTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAAACTCATGCAAAGGAGCATAAGAATCTCGC
  AGAAGCTTTATTGACCTATGAGACTTTGGATGCCAAAGAGATTCAAATTGTTCTTGAGGGGAAAAAGTTG
  GAAGTGAGATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139312 unedited
  GGAGGGTTCANCATTTGNTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCTG
  TAGGAAGGGGAGGCCATTTTCCGTTTCTGGGAGGAGTGAGGGGCAACGGGTCGGAGAAAA
  AGGAAAAAAGAAGGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGGGCACAGTTTCG
  GCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCGAGCACGGTGCA
  ACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACACCAAAAAACAC
  TTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGATGTAGTTCCTGA
  GCATGAGGCTCCCAGCAGTGAGCCTTCACTTAACTTAAGGGACCTTGGATTATCTGAACT
  AAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTCCTGGATTTTGTAAAGGCAA
  AAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTTGAAAATAA
  ATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTC
  AAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTTTCATACAGTCTCG
  GGGTTTTAAAACTTTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGC
  TGANACACAGAATATAGCGCCATCATTCGTGAAAGGGTTTCTTTTGCGGGACAGAGGGAT
  CAGATGTGAGAGTTTGGACANACTCATGAAAAACCAAAAATATACCTGAAGCTCACCAAG
  ATGCATTTAAAACTGTNTTTGCNGAAAGGGTTTCTGAAAGCTCAAGCCN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_139312 unedited
  ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTTTCAAACCTGATAG
  TTCTTTATTTTTTCAAAATATATTTGCCATGGGATGCTAATTTGCAATAGGTGTCATAAT
  GAGAATAACCCAAACTGGATAAATGTGACAAATGATTGACAAAGCATTTCACACCCTTCA
  ATTACACCACATCAAGAATGAGGGGAAAGCGTTGTAAAAGTAGACTACTGCAATGCTACT
  TATATTCTTGCAATAAAACCAGCAAGCATCCATATCAAGAGAGTTATCATCTCACTTCCA
  ACTTTTTCCCCTCAAGAACAATTTGAATCTCTTTGGCATCCAAAGTCTCATAGGTCAATA
  AAGCTTCTGCGAGATTCTTATGCTCCTTTGCATGAGTTTTCAAGATATGTTTTGCTCGTT
  CATATGAGTCCCTTAGAAGGATTCTTATTTCTTGTTCGATGGCAGATTGGGTTTCTGGAC
  TTAGTTTCCCTGTATCACTGTAGGTCATAACTCCAAGCTTTTCACTCATTCCAAATTTGG
  TAACCATCCGCTTTGCTATTTTAGTGGCATTATCAAAATCACTGGAAGCACCTGTTGTAA
  TATGGTCGGTTCCAAATATAAGCTCCTCTGCCACTCTTCCTCCCATACTAACATCCATTT
  GTGCAAGCAGCTGGGCTCTAGTTTCATTCCATCTGTCATTCTCAGGTAACAGGGACACAT
  GTCCAAGTGTTGGCCCCCGTGGCATGATTGTAGCTTTGNTGATAGGCATTGCATNCTTTT
  GTGTATATGCCATAATGGCATGACCAGATTCATGAATGCTGTGATGGTTTTGTTTTTGTA
  TCATTTCCACACTTCTTCTTCAGCCCCATAGAATTTGTCTTTGGAAAACTCACTCCTCAT
  GGTACATTTCTTTTCTCACAGCTGCTTTATGCAGCCTGGTACCAGATCTTCACTTGCTCC
  GAAAGCAACATACTGCGCTTAATTTGGTCAACGATGTCAAACTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_139312
• ORF Size: 2322 bp
• Insert Size: 2650
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_139312.1, NP_647473.1
• RefSeq Size: 4403
• RefSeq ORF: 2322
• Locus ID: 10730
• Domains: Peptidase_M41, AAA
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.