ACSL5 (NM_203379) Human Untagged Clone

CAT#: SC121567

ACSL5 (untagged)-Human acyl-CoA synthetase long-chain family member 5 (ACSL5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACSL5
• Synonyms: ACS2; ACS5; FACL5
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC121567 sequence for NM_203379 edited (data generated by NextGen Sequencing)
  ATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATC
  CTGACATTTGGAGCTGCCATCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCT
  CTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAAGGGGGTTTCC
  CAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTT
  TTCCAAAGAGGACTCGCTGTGTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAAC
  CAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTACCTGGGTTCC
  TGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAG
  AATAGGCCAGAGTGGATCATCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTA
  CCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAAGGCTGATATC
  GCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAA
  GGCTTCACCCCGAGCCTGAAGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAG
  CAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGAGAACCTAGGC
  AAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTC
  ACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCA
  AATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCCTGATGATGTG
  GCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTAC
  AGCTGTGGAGCCAGAGTTGGATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATG
  AAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAGGATCTACGAT
  AAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCC
  AGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTC
  ATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGTCACTGGAGCT
  GCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTAT
  GAAGCTTATGGTCAAACAGAATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGG
  ACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGAAGATGTGGCT
  GACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTG
  TTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGG
  CTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGATCATCGACCGT
  AAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAAT
  ATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCA
  TCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGCAGCCAAGCTT
  GGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAAGTTGTAAGGGAAGCCATTTTA
  GAAGACTTGCAGAAAATTGGGAAAGAAAGTGGCCTTAAAACTTTTGAACAGGTCAAAGCC
  ATTTTTCTTCATCCAGAGCCATTTTCCATTGAAAATGGGCTCTTGACACCAACATTGAAA
  GCAAAGCGAGGAGAGCTTTCCAAATACTTTCGGACCCAAATTGACAGCCTGTATGAGCAC
  ATCCAGGATTAG
  
  Clone variation with respect to NM_203379.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_203379 unedited
  GCCCCCCGGGGGGGCCNNNNNCNNCNCNNNCCCNNCNNCCNCCCCCCGCCCGGTTCACAT
  TTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGAAAGATAGAAGTGCCT
  NGATGTGGTGCNTGAATCAATACAGCCAGCTGTGAGGGGAGCACTTCCTGGACCCAGGAA
  GGGAGAGTCTTCTTCCAGGTCTGAATTTCCTGCTGCTGTTCACAAAGATGCTTTTTATCT
  TTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAG
  CTGCCATCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGA
  ACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAAGGGGGTTTCCCAGAAGAACAATG
  ACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGAC
  TCGCTGTGTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGAT
  GGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTACCTGNGTTCCTGTCTCTTGCATA
  AAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGT
  GGATCATCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACA
  CCTTGGGACCAGAAGCCATCGTACATATTGTCAACAAGGCTGATATCGCCATGGGTGATC
  TGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTANAGAAAGGCTTCCCCCCG
  AGCTGAAAGTGATCATCCTTATGGACCCCCTTGATGATGACCTGAAAGCAAGAGGGGGAG
  AAGATGGAAATTGAGATCTTATCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_203379 unedited
  NATGGGGTGGCACTTCCAGGNCCAGGNANGAGCACTGGGGNAGGGTCACAGGGATGCCAC
  CCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTT
  TTTTTTTTTTTTTTAAGTATCTGTAATAGTTTATTTTAAAGACTTTACATTTACAAGTAG
  AAACAACATGTGTTATCTGTGGGTAAGGTAGAGCAGGAACTCTAATCCAAGGGTGGGGGA
  GATCAGTTGGTTCCTTCACAGAAAATAAGCCTGTTGTGTGGGCATCTTGCTTGCCTGTAG
  ATCTTTGTTCCCAGTTCAGGAGGTTTTTATTCAGTGCTTGCTTCATTTACTGGAAAAGTT
  CACTGGGCCCACCTGTCAACTCCTTCCCCCACAGCTTCCAGCTCAGCAGCAAACTGTAGG
  GAACAGATTTACTCCCCAGTTCCTACTGTAAATAATGCTTTAAGAACAGCATTCCTTTTG
  GACAATATGTCATAGACCCAATTTTTAATACTCCCAAGTCAGATATCTAACTAGAGAGTT
  TAGGAAATGTTTGGTATGATCAAACTTTTCCCTTCAGTACACAATTTAATTTACGCAGAA
  NAGCCTCGGAGACATTTGTCTCATAGATATGATTGACATGAGTGATAGGCTAAAACTAAA
  ATTTTAGTGGTTTGGGGAGTGGCCTAGAAACCTGAATTTGAACCACTTTTTTCAGAATTA
  AAAAATCTCTTAATTTGAACCATGCAAAAAGTGAATTAGCCTACAAACCTTTTGGCAGGT
  TTTGTTATTCCAGAAACAAAGAAAAAGGCACCGAAGGGTCCCCTTTGCACCCTATGCACT
  TGTGGGTTCCCAACAANTATTAAGGGTGGGAAAGCCCGGAAGAAGGGCCGCCGCACATAA
  ATCTGGTTTTCTGAGACACAGGTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_203379
• ORF Size: 2052 bp
• Insert Size: 2800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_203379.1, NP_976313.1
• RefSeq Size: 3233
• RefSeq ORF: 2052
• Locus ID: 51703
• Protein Families: Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. This results in translation initiation from a downstream ATG and an isoform (b) that has a shorter N-terminus compared to isoform a. Both variants 2 and 3 encode isoform b.