P2RX4 (NM_002560) Human Untagged Clone

CAT#: SC122124

P2RX4 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: P2RX4
• Synonyms: P2X4; P2X4R
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC122124 sequence for NM_002560 edited (data generated by NextGen Sequencing)
  ATGGCGGGCTGCTGCGCCGCGCTGGCGGCCTTCCTGTTCGAGTACGACACGCCGCGCATC
  GTGCTCATCCGCAGCCGCAAAGTGGGGCTCATGAACCGCGCCGTGCAACTGCTCATCCTG
  GCCTACGTCATCGGGTGGGTGTTTGTGTGGGAAAAGGGCTACCAGGAAACTGACTCCGTG
  GTCAGCTCCGTTACGACCAAGGTCAAGGGCGTGGCTGTGACCAACACTTCTAAACTTGGA
  TTCCGGATCTGGGATGTGGCGGATTATGTGATACCAGCTCAGGAGGAAAACTCCCTCTTC
  GTCATGACCAACGTGATCCTCACCATGAACCAGACACAGGGCCTGTGCCCCGAGATTCCA
  GATGCGACCACTGTGTGTAAATCAGATGCCAGCTGTACTGCCGGCTCTGCCGGCACCCAC
  AGCAACGGAGTCTCAACAGGCAGGTGCGTAGCTTTCAACGGGTCCGTCAAGACGTGTGAG
  GTGGCGGCCTGGTGCCCGGTGGAGGATGACACACACGTGCCACAACCTGCTTTTTTAAAG
  GCTGCAGAAAACTTCACTCTTTTGGTTAAGAACAACATCTGGTATCCCAAATTTAATTTC
  AGCAAGAGGAATATCCTTCCCAACATCACCACTACTTACCTCAAGTCGTGCATTTATGAT
  GCTAAAACAGATCCCTTCTGCCCCATATTCCGTCTTGGCAAAATAGTGGAGAACGCAGGA
  CACAGTTTCCAGGACATGGCCGTGGAGGGAGGCATCATGGGCATCCAGGTCAACTGGGAC
  TGCAACCTGGACAGAGCCGCCTCCCTCTGCTTGCCCAGGTACTCCTTCCGCCGCCTCGAT
  ACACGGGACGTTGAGCACAACGTATCTCCTGGCTACAATTTCAGGTTTGCCAAGTACTAC
  AGAGACCTGGCTGGCAACGAGCAGCGCACGCTCATCAAGGCCTATGGCATCCGTTTCGAC
  ATCATTGTGTTTGGGAAGGCAGGGAAATTTGACATCATCCCCACTATGATCAACATCGGC
  TCTGGCCTGGCACTGCTAGGCATGGCGACCGTGCTGTGTGACATCATAGTCCTCTACTGC
  ATGAAGAAAAGACTCTACTATCGGGAGAAGAAATATAAATATGTGGAAGATTACGAGCAG
  GGTCTTGCTAGTGAGCTGGACCAGTGA
  
  Clone variation with respect to NM_002560.2
  465 t=>c;954 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002560 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCAGACCGACTAGG
  GGACTGGGAGCGGGCGGCGCGGTCATGGCGGGCTGCTGCGCCGCGCTGGCGGCCTTCCTG
  TTCGAGTACGACACGCCGCGCATCGTGCTCATCCGCAGCCGCAAAGTGGGGCTCATGAAC
  CGCGCCGTGCAACTGCTCATCCTGGCCTACGTCATCGGGTGGGTGTTTGTGTGGGAAAAG
  GGCTACCAGGAAACTGACTCCGTGGTCAGCTCCGTTACGACCAAGGTCAAGGGCGTGGCT
  GTGACCAACACTTCTAAACTTGGATTCCGGATCTGGGATGTGGCGGATTATGTGATACCA
  GCTCAGGAGGAAAACTCCCTCTTCGTCATGACCAACGTGATCCTCACCATGAACCAGACA
  CAGGGCCTGTGCCCCGAGATTCCAGATGCGACCACTGTGTGTAAATCAGATGCCAGCTGT
  ACTGCCGGCTCTGCCGGCACCCACAGCAACGGAGTCTCAACAGGCAGGTGCGTAGCTTTC
  AACGGGTCCGACAAGACGTGTGAGGTGGCGGCCTGGTGCCCTGTGGCAGATGACACACAC
  GTGCCACAACCTGCTTTTTTAAAGGCTGCAGAAAACTTCACTCTTTGTGGTTAACAACAA
  CATCTGGTATCCCAAATGTAATTTCAGGAAGAGGAGTATTCTTTCCAACATCCCCACTAC
  TGACCTAAAGTCGTGCATTTTTGATGCTAAAACACATCCCTTCTCGCCCATTATTCCGCC
  TGGCAACATAGTGGAAAACGCAGAACCAGTTTTCCAGACATGGCCGCGGAGGGAAGCCTT
  ATGGGCATCCACGCAACTTGGGACTGCAACCTGGACAAAGCCGTCTCCTTTTGGTTGCCA
  AG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002560 unedited
  CCGCGGCCGCAATCNATAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTAAAAAAAATCACGCTTTAATGTCTGGGCCTCGATCACCTTAGCCCAGC
  CCTTTTTTGAGGAAAAATGCCAACTCTTCCCCATGGCTTCAGGGAATGGGCGGGGGGAAA
  CCTGCACCCCAACCCTGCTACAAATTTAGTTTCTGGAACCAGGCGGCCTCCCCTGGGGGA
  TAAAATGCTTGAACAAACCCCCCCTGCCTAAAAGGACTGGGCCTGTCCTGGAAAAAGCTG
  GAAACCGGAGGCCTCTGAACAAAACCGGTTCCACCCCTGAAACCCCAATAGTGCCACCGT
  GCGTGGCCACCGCTCCCCCCAAACCCCCAGGGCGGGGGAAAACCTAAGTTCCCCCCATCA
  AGAACAGACTGCTTCTCTCTTGTGGCGAGTGGGCAACCCCTCCCTGCCACCACTCCAAAG
  CACCCTTGGGGCACCCTGTGTCCTCCCGCCTCGGCCCCCATCCCAATTCAAACAGCCTCT
  GCGAGAGTTGGGGCCCCTTCCCCCTTTCTCTCCCTCTTTTTCCTCCCCGGGCGCCTCCGT
  ATCCCCCTCCTCGGTCCCCCCCCCTTCCTCCCCCCCGCTCACCCCACATCTCCCATACTA
  CTCACCCAATTTCTCTCCTCCCCCCACTTCCACTCTTTCACCTCCCTCTCTCCACGCCCT
  CCCTTCCCAATCTCCCCCGCCACCCTTCCCTCCTCCCCTCCCCCCATTCCCTTTCCCCCT
  TTCGCCACCTCTATCCCCGTGTCCTTTTATCCATTCCCCCTTTTCACCCTACCTATTCCC
  ACTCCACACTATTTGTCTCTTTACACCTCCTGTTCACCCCCCCCTCCCTTTTCTTTTGTA
  AGCGTGTGACCCCCCCTGCCCTTTCCCCCTCTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002560
• ORF Size: 1167 bp
• Insert Size: 1910
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_002560.2, NP_002551.2
• RefSeq Size: 2043
• RefSeq ORF: 1167
• Locus ID: 5025
• Domains: P2X_receptor
• Protein Families: Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Sequence Note: Translation provided for the transcript variants two and three is predicted. The start codon is the same as in the predominant transcript variant (1).