P2RX4 (NM_002560) Human Untagged Clone

CAT#: SC324305

P2RX4 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: P2RX4
• Synonyms: P2X4; P2X4R
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002560.2 GGACTGGGAGCGGGCGGCGCGGCCATGGCGGGCTGCTGCGCCGCGCTGGCGGCCTTCCTG
  TTCGAGTACGACACGCCGCGCATCGTGCTCATCCGCAGCCGCAAAGTGGGGCTCATGAAC
  CGCGCCGTGCAACTGCTCATCCTGGCCTACGTCATCGGGTGGGTGTTTGTGTGGGAAAAG
  GGCTACCAGGAAACTGACTCCGTGGTCAGCTCCGTTACGACCAAGGTCAAGGGCGTGGCT
  GTGACCAACACTTCTAAACTTGGATTCCGGATCTGGGATGTGGCGGATTATGTGATACCA
  GCTCAGGAGGAAAACTCCCTCTTCGTCATGACCAACGTGATCCTCACCATGAACCAGACA
  CAGGGCCTGTGCCCCGAGATTCCAGATGCGACCACTGTGTGTAAATCAGATGCCAGCTGT
  ACTGCCGGCTCTGCCGGCACCCACAGCAACGGAGTCTCAACAGGCAGGTGCGTAGCTTTC
  AACGGGTCCGTCAAGACGTGTGAGGTGGCGGCCTGGTGCCCGGTGGAGGATGACACACAC
  GTGCCACAACCTGCTTTTTTAAAGGCTGCAGAAAACTTCACTCTTTTGGTTAAGAACAAC
  ATCTGGTATCCCAAATTTAATTTCAGCAAGAGGAATATCCTTCCCAACATCACCACTACT
  TACCTCAAGTCGTGCATTTATGATGCTAAAACAGATCCCTTCTGCCCCATATTCCGTCTT
  GGCAAAATAGTGGAGAACGCAGGACACGGTTTCCAGGACATGGCCGTGGAGGGAGGCATC
  ATGGGCATCCAGGTCAACTGGGACTGCAACCTGGACAGAGCCGCCTCCCTCTGCTTGCCC
  AGGTACTCCTTCCGCCGCCTCGATACACGGGACGTTGAGCACAACGTATCTCCTGGCTAC
  AATTTCAGGTTTGCCAAGTACTACAGAGACCTGGCTGGCAACGAGCAGCGCACGCTCATC
  AAGGCCTATGGCATCCGCTTCGACATCATTGTGTTTGGGAAGGCAGGGAAATTTGACATC
  ATCCCCACTATGATCAACATCGGCTCTGGCCTGGCACTGCTAGGCATGGCGACCGTGCTG
  TGTGACATCATAGTCCTCTACTGCATGAAGAAAAGACTCTACTATCGGGAGAAGAAATAT
  AAATATGTGGAAGATTACGAGCAGGGTCTTGCTAGTGAGCTGGACCAGTGAGGCCTACCC
  CACACCTGGGCTCTCCACAGCCCCATCAAAGAACAGAGAGGAGGAGGAGGGAGAAATGGC
  CACCACATCACCCCAGAGAAATTTCTGGAATCTGATTGAGTCTCCACTCCACAAGCACTC
  AGGGTTCCCCAGCAGCTCCTGTGTGTTGTGTGCAGGATCTGTTTGCCCACTCGGCCCAGG
  AGGTCAGCAGTCTGTTCTTGGCTGGGTCAACTCTGCTTTTCCCGCAACCTGGGGTTGTCG
  GGGGAGCGCTGGCCCGACGCAGTGGCACTGCTGTGGCTTTCAGGGCTGGAGCTGGCTTTG
  CTCAGAAGCCTCCTGTCTCCAGCTCTCTCCAGGACAGGCCCAGTCCTCTGAGGCACGGCG
  GCTCTGTTCAAGCACTTTATGCGGCAGGGGAGGCCGCCTGGCTGCAGTCACTAGACTTGT
  AGCAGGCCTGGGCTGCAGGCTTCCCCCCGACCATTCCCTGCAGCCATGCGGCAGAGCTGG
  CATTTCTCCTCAGAGAAGCGCTGTGCTAAGGTGATCGAGGACCAGACATTAAAGCGTGAT
  TTTCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002560.2 unedited
  GGCCAAGCCTGGAAGCCTCCCGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATCCA
  GCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCTAT
  GACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTGGT
  ACCGGTCCGGAATTCCCGGGATGGACTGGGAGCGGGCGGCGCGGCCATGGCGGGCTGCTG
  CGCCGCGCTGGCGGCCTTCCTGTTCGAGTACGACACGCCGCGCATCGTGCTCATCCGCAG
  CCGCAAAGTGGGGCTCATGAACCGCGCCGTGCAACTGCTCATCCTGGCCTACGTCATCGG
  GTGGGTGTTTGTGTGGGAAAAGGGCTACCAGGAAACTGACTCCGTGGTCAGCTCCGTTAC
  GACCAAGGTCAAGGGCGTGGCTGTGACCAACACTTCTAAACTTGGATTCCGGATCTGGGA
  TGTGGCGGATTATGTGATACCAGCTCAGGAGGAAAACTCCCTCTTCGTCATGACCAACGT
  GATCCTCACCATGAACCAGACACAGGGCCTGTGCCCCGAGATTCCAGATGCGACCACTGT
  GTGTAAATCAGATGCCAGCTGTACTGCCGGCTCTGCCGGCACCCACAGCAACGGAGTCTC
  AACAGGCAGGTGCGTAGCTTTCAACGGGTCCGTCAAGACGTGTGAGGTGGCGGCCTGTGC
  CCGGTGGAGGATGACACACACGTGCCACAACCCTGCTTTTTTAAGGCTGCAGAAAACTTC
  ACTCTTTTGGTTAGACAACATCTGGTATCCCAAATTTAATTTCAGCAGAGGATATCTCCA
  ACATCACCACTACTACCTCAGTCGTGCATTTATGATGCTAAACAGATCCCTTCTGCCCAT
  ATCGTCTTGCAAATATGGAGACGCAGACACAGGTCCAGGACATGCCGTGGAGGGAGAGGC
  CATCATGGCATC
• Restriction Sites: Please inquire
• ACCN: NM_002560
• ORF Size: 1167 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_002560.2, NP_002551.2
• RefSeq Size: 2043
• RefSeq ORF: 1167
• Locus ID: 5025
• Domains: P2X_receptor
• Protein Families: Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Sequence Note: Translation provided for the transcript variants two and three is predicted. The start codon is the same as in the predominant transcript variant (1).