SFTPB (NM_000542) Human Untagged Clone

CAT#: SC122565

SFTPB (untagged)-Human surfactant protein B (SFTPB), transcript variant 1


  "NM_000542" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SFTPB
Synonyms PSP-B; SFTB3; SFTP3; SMDP1; SP-B
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000542 edited
GCCATGGCTGAGTCACACCTGCTGCAGTGGCTGCTGCTGCTGCTGCCCACGCTCTGTGGC
CCAGGCACTGCTGCCTGGACCACCTCATCCTTGGCCTGTGCCCAGGGCCCTGAGTTCTGG
TGCCAAAGCCTGGAGCAAGCATTGCAGTGCAGAGCCCTAGGGCATTGCCTACAGGAAGTC
TGGGGACATGTGGGAGCCGATGACCTATGCCAAGAGTGTGAGGACATCGTCCACATCCTT
AACAAGATGGCCAAGGAGGCCATTTTCCAGGACACGATGAGGAAGTTCCTGGAGCAGGAG
TGCAACGTCCTCCCCTTGAAGCTGCTCATGCCCCAGTGCAACCAAGTGCTTGACGACTAC
TTCCCCCTGGTCATCGACTACTTCCAGAACCAGACTGACTCAAACGGCATCTGTATGCAC
CTGGGCCTGTGCAAATCCCGGCAGCCAGAGCCAGAGCAGGAGCCAGGGATGTCAGACCCC
CTGCCCAAACCTCTGCGGGACCCTCTGCCAGACCCTCTGCTGGACAAGCTCGTCCTCCCT
GTGCTGCCCGGGGCCCTCCAGGCGAGGCCTGGGCCTCACACACAGGATCTCTCCGAGCAG
CAATTCCCCATTCCTCTCCCCTATTGCTGGCTCTGCAGGGCTCTGATCAAGCGGATCCAA
GCCATGATTCCCAAGGGTGCGCTAGCTGTGGCAGTGGCCCAGGTGTGCCGCGTGGTACCT
CTGGTGGCGGGCGGCATCTGCCAGTGCCTGGCTGAGCGCTACTCCGTCATCCTGCTCGAC
ACGCTGCTGGGCCGCATGCTGCCCCAGCTGGTCTGCCGCCTCGTCCTCCGGTGCTCCATG
GATGACAGCGCTGGCCCAAGGTCGCCGACAGGAGAATGGCTGCCGCGAGACTCTGAGTGC
CACCTCTGCATGTCCGTGACCACCCAGGCCGGGAACAGCAGCGAGCAGGCCATACCACAG
GCAATGCTCCAGGCCTGTGTTGGCTCCTGGCTGGACAGGGAAAAGTGCAAGCAATTTGTG
GAGCAGCACACGCCCCAGCTGCTGACCCTGGTGCCCAGGGGCTGGGATGCCCACACCACC
TGCCAGGCCCTCGGGGTGTGTGGGACCATGTCCAGCCCTCTCCAGTGTATCCACAGCCCC
GACCTTTGATGAGAACTCAGCTGTCCAGCTGCAAAGGAAAAGCCAAGTGAGACGGGCTCT
GGGACCATGGTGACCAGGCTCTTCCCCTGCTCCCTGGCCCTCGCCAGCTGCCAGGCTGAA
AAGAAGCCTCAGCTCCCACACCGCCCTCCTCACCGCCCTTCCTCGGCAGTCACTTCCACT
GGTGGACCACGGGCCCCCAGCCCTGTGTCGGCCTTGTCTGTCTCAGCTCAACCACAGTCT
GACACCAGAGCCCACTTCCATCCTCTCTGGTGTGAGGCACAGCGAGGGCAGCATCTGGAG
GAGCTCTGCAGCCTCCACACCTACCACGACCTCCCAGGGCTGGGCTCAGGAAAAACCAGC
CACTGCTTTACAGGACAGGGGGTTGAAGCTGAGCCCCGCCTCACACCCACCCCCATGCAC
TCAAAGATTGGATTTTACAGCTACTTGCAATTCAAAATTCAGAAGAATAAAAAATGGGAA
CATACAGAACTCTAAAAGATAGACATCAGAAATTGTTAAGTTAAGCTTTTTCAAAAAATC
AGCAATTCCCCAGCGTAGTCAAGGGTGGACACTGCACGCTCTGGCATGATGGGATGGCGA
CCGGGCAAGCTTTCTTCCTCGAGATGCTCTGCTGCTTGAGAGCTATTGCTTTGTTAAGAT
ATAAAAAGGGGTTTCTTTTTGTCTTTCTGTAAGGTGGACTTCCAGCTTTTGATTGAAAGT
CCTAGGGTGATTCTATTTCTGCTGTGATTTATCTGCTGAAAGCTCAGCTGGGGTTGTGCA
AGCTAGGGACCCATTCCTGTGTAATACAATGTCTGCACCAATGCTAATAAAGTCCTATTC
TCTTTTATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_000542 unedited
GCGCTCAGATTTTGTAATACGACTTCACTATAGGGCGGCCGCGATTCCCGGGATGCCATG
GCTGAGTACACCTGCTGCAGTGGCTGCTGCTGCTGCTGCCCACGCTCTGTGGCCCAGGCA
CTGCTGCCTGGACCACCTCATCCTTGGCCTGTGCCCAGGGCCCTGAGTTCTGGTGCCAAA
GCCTGGAGCAAGCATTGCAGTGCAGAGCCCTAGGGCATTGCCTACAGGAAGTCTGGGGAC
ATGTGGGAGCCGATGACCTATGCCAAGAGTGTGAGGACATCGTCCACATCCTTAACAAGA
TGGCCAAGGAGGCCATTTTCCAGGACACGATGAGGAAGTTCCTGGAGCAGGAGTGCAACG
TCCTCCCCTTGAAGCTGCTCATGCCCCAGTGCAACCAAGTGCTTGACGACTACTTCCCCC
TGGTCATCGACTACTTCCAGAACCAGACTGACTCAAACGGCATCTGTATGCACCTGGGCC
TGTGCAAATCCCGGCAGCCAGAGCCAGAGCAGGAGCCAGGGATGTCAGACCCCCTGCCCA
AACCTCTGCGGGACCCTCTGCCAGACCCTCTGCTGGACAAGCTCGTCCTCCCTGTGCTGC
CCGGGGCCCTCCAGGCGAGGCCTGGGCCTCACACACAGGATCTCTCCGAGCAGCAATTCC
CCATTCCTCTCCCCTATTGCTGGCTCTGCAGGGCTCTGATCAAGCGGATCCAAGCCATGA
TTCCCAAGGGTGCGCTAGCTGTGGCAGTGGCCCANGTGTGCCGCGTGGTACCTCTGGTGG
CGGGCGGCATCTGCCAGTGCCTGGCTGAGCGCTACTCCGTCATCCTGCTCGACACGCTGC
TGGGCCGCATGCTGCCCCAGCTGGTCTGCCGCCTCGTCCTCCGGGTGCTCATGGATGACA
GCGC
Restriction Sites Please inquire     
ACCN NM_000542
Insert Size 2026 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000542.2, NP_000533.2
RefSeq Size 2026 bp
RefSeq ORF 1146 bp
Locus ID 6439
Cytogenetics 2p11.2
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]'
Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein.

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