NPTX2 (NM_002523) Human Untagged Clone

CAT#: SC122629

NPTX2 (untagged)-Human neuronal pentraxin II (NPTX2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NPTX2
• Synonyms: NARP; NP-II; NP2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002523 edited
  GAGCAGCGCGGTGGGTGCGGCTGTGAGACGGCAGGAGACTTCTGCCCCGCGGTGCACGCG
  ACCCTCGAGACGACAGCGCGGCTACTGCCAGCAGCGAAGGCGCCTCCCGCGGAGCGCCCC
  GACGGCGCCCGCTCGCCCATGCCGAGCTGAGCGCGGCAGCGGCGGCGGGATGCTGGCGCT
  GCTGGCCGCCAGCGTGGCGCTCGCCGTGGCCGCTGGGGCCCAGGACAGCCCGGCGCCCGG
  TAGCCGCTTCGTGTGCACGGCACTGCCCCCAGAGGCGGTGCACGCCGGCTGCCCGCTGCC
  CGCGATGCCCATGCAGGGCGGCGCGCAGAGTCCCGAGGAGGAGCTGAGGGCCGCGGTGCT
  GCAGCTGCGCGAGACCGTCGTGCAGCAGAAGGAGACGCTGGGCGCGCAGCGCGAGGCCAT
  CCGCGAGCTCACGGGCAAGCTAGCGCGCTGCGAGGGGCTGGCGGGCGGCAAGGCGCGCGG
  CGCGGGGGCCACGGGCAAGGACACTATGGGCGACCTGCCGCGGGACCCCGGCCACGTCGT
  GGAGCAGCTCAGCCGCTCGCTGCAGACCCTCAAGGACCGCCTGGAGAGCCTCGAGCACCA
  GCTCAGAGCAAACGTGTCCAATGCTGGGCTGCCCGGCGACTTCCGCGAGGTGCTCCAGCA
  GCGGCTGGGGGAGCTGGAGAGGCAGCTTCTGCGCAAGGTGGCAGAGCTGGAGGACGAGAA
  GTCCCTGCTGCACAATGAGACCTCGGCTCACCGGCAGAAGACCGAGAGCACCCTGAACGC
  GCTGCTGCAGAGGGTCACCGAGCTGGAGCGAGGCAATAGCGCCTTTAAGTCACCAGATGC
  GTTCAAGGTGTCCCTCCCACTCCGCACAAACTACCTATACGGCAAGATCAAGAAGACGCT
  GCCTGAGCTGTACGCCTTCACCATCTGCCTGTGGCTGCGGTCCAGCGCCTCACCAGGCAT
  TGGCACCCCCTTCTCCTATGCGGTGCCAGGGCAGGCCAACGAGATCGTGCTGATCGAGTG
  GGGCAACAACCCCATCGAGCTGCTCATCAACGACAAGGTTGCGCAGCTGCCCCTGTTTGT
  CAGTGACGGCAAGTGGCACCACATCTGTGTCACCTGGACGACACGGGATGGCATGTGGGA
  GGCATTCCAGGACGGAGAGAAGCTGGGCACTGGGGAGAACCTGGCCCCCTGGCACCCCAT
  CAAGCCCGGGGGCGTGCTGATCCTTGGACAAGAGCAGGACACCGTGGGGGGTAGGTTTGA
  TGCCACTCAGGCATTTGTCGGGGAGCTCAGCCAGTTCAACATATGGGACCGCGTCCTTCG
  CGCACAAGAAATTGTCAACATCGCCAACTGCTCCACAAACATGCCGGGCAACATCATCCC
  GTGGGTGGACAATAACGTCGATGTGTTCGGAGGGGCCTCCAAGTGGCCCGTGGAGACGTG
  TGAGGAGCGTCTCCTTGACTTGTAGCCGCCTTCTCCTCTGTCCAGGAGGCCGGGATCAGG
  CTGTTGCCATGGAAGTTCAGGGCCATAGACTGCCCCACTTAAACTCTTGTCAGTCTGGGC
  TCAGGGTTCCCAGAGCTCATTCCCCAGGAATCTCTAAGACCAGGGCTGGGGCAGTGTCTG
  TCACTGGCTTGTTTGTTCCCTACCAATATTCTGTTGCTGTTTGAAGTAGTGCCAGGGTCC
  CCTGGGAAGATGCCCCCAAGACACCTGCCCCAAGTGGGTGGATATCTGCCTTCCTGCTGC
  AAGTGGAGGCAGGTCCAGCAGCCCCTCTTCAGAGCCCCTGTAAATGCTATCGCAGCCTGA
  GTCCTGCCGCCTTCCAGTTCCTTGGTGTCCCGTGCACCCCTTCTGTCTGTCCCCTTTCAT
  GGCTGTGCAGCCGTCCCGCTGGAGTGGCCATGTCCCTTGTGCATTGAGTGCATCCCCGCT
  GGTGACTAAGCTCGCAGCAAGCGGCTACCCCCCGATCTGCAAAAGGGCCTCTCCCTTTGT
  GTTCTATACATTGTGAATCTTCCCGTCTGAAGAACGCCCAGCCTGCCCAGACAAAGCCCC
  GCCTTCCCCAAAGCAGAGGGGCTGTCTGTGTCTCCAGAAAGGGGACATCGGGGGGGAGGG
  GGGCTCAGAAAGGAGAAGGGCTGTGATCTCCGGTCCCTTCCCCCATCATCCTTCCTTAGA
  CTGATGCTTTGACTGAATCATCACTAGCTATGGCATTAAAAGGCCTCTCTTCTCATCTGG
  TGCCAAAGGTTCCGTTGCAGCTTTTTACAACCATCCGGTGTGGTTTGGAGGATTTGTTTT
  TTTTTTTTCCCAACAGAAAAGAACAGCCATTAGAAGAAGGCTCCCATTTTCTGATGTTCC
  GCCCCACTGTGAAGAGTGTGCTCGTTTTAAATTCATGTTGATTCTTGTAAGCACTGGACT
  GTCTTCATCAAGTATTTCCCTACAGAACTCCTCAAGAAAACAGAGATCATTTGGCTAGAG
  ATTGTCTGAGTGACTCCAAGCTACTCACTGTATTGGACGGGAGTAGTAATTTATTTTAAA
  GATAAAGTGACTAAGTGGGGAAATTTATAAAGCTAAATATTATATATTTTATTTTTCATA
  CATGTTTGAAGTGCAAATCTGTGGATATTCCATTTGTAGGACCAAGTCGACATGCCCATC
  CTGACATTGTATGCTACGAGAACTCTTCTGATGATGGAATTTCGATTAAAGTGCACTGAA
  AGATGAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002523 unedited
  GAAGCGGTCATTTTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGAGC
  AGCGCGGTGGGTGCGGCTGTGAGACGGCAGGAGACTTCTGCCCCGCGGTGCACGCGACCC
  TCGAGACGACAGCGCGGCTACTGCCAGCAGCGAAGGCGCCTCCCGCGGAGCGCCCCGACG
  GCGCCCGCTCGCCCATGCCGAGCTGAGCGCGGCAGCGGCGGCGGGATGCTGGCGCTGCTG
  GCCGCCAGCGTGGCGCTCGCCGTGGCCGCTGGGGCCCAGGACAGCCCGGCGCCCGGTAGC
  CGCTTCGTGTGCACGGCACTGCCCCCAGAGGCGGTGCACGCCGGCTGCCCGCTGCCCGCG
  ATGCCCATGCAGGGCGGCGCGCAGAGTCCCGAGGAGGAGCTGAGGGCCGCGGTGCTGCAG
  CTGCGCGAGACCGTCGTGCAGCAGAAGGAGACGCTGGGCGCGCAGCGCGAGGCCATCCGC
  GAGCTCACGGGCAAGCTAGCGCGCTGCGAGGGGCTGGCGGGCGGCAAGGCGCGCGGCGCG
  GGGGCCACGGGCAAGGACACTATGGGCGACCTGCCGCGGGACCCCGGCCACGTCGTGGAG
  CAGCTCAGCCGCTCGCTGCAGACCCTCAAGGACCGCCTGGAGAGCCTCGAGCACCAGCTC
  AGAGCAAACGTGTCCAATGCTGGGCTGCCCGGCGACTTCCGCGAGGTGCTCCAGCANCGG
  CTGGGGGAGCTGGAGAGGCANCTTCTGCGCAGGGTGGCAAAGCTGGAGGACGAGAAGTCC
  TGCTGCACAAGAGACCTCGGCTCACGGCAGAAGACCGAGAGCACCTGAACCGCTGCTGCA
  GAGGTCACCGAACTGGAACGAGGCAATAGCCCCTTTAATCACCAGAAGCGTTCAAGG
  
• Restriction Sites: Please inquire
• ACCN: NM_002523
• Insert Size: 2739 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002523.1, NP_002514.1
• RefSeq Size: 2746 bp
• RefSeq ORF: 1296 bp
• Locus ID: 4885
• Cytogenetics: 7q22.1
• Protein Families: Secreted Protein
• Gene Summary: 'This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]'