ARHGEF14 (MCF2L) (NM_024979) Human Untagged Clone

CAT#: SC122978

MCF2L (untagged)-Human MCF.2 cell line derived transforming sequence-like (MCF2L), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCF2L
• Synonyms: ARHGEF14; DBS; OST
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024979 edited
  GGCTGCCCTGCAGAGGCCAGGTCTGCCCAGCAAACCCAGGAAGGTGTGGCGTCCCCGCTT
  CGCGGCCAAGATGGTGCTGGTGCTGCGCCATCCTTTGTGTGCCCGGGAAGGGCGTTCCGG
  GAGCCGGGTCGGGGGCTCCTGACTCGCATTGGGCAGCATGACGGTGCGCCGGCTGTCACT
  GCTGTGCCGGGACCTCTGGGCGCTGTGGCTGCTGCTGAAGGCCGGCGCAGATGAAATCAT
  GCACCAGGACATCGTCCCGCTCTGTGCTGCCGACATCCAGGACCAGCTAAAGAAGCGCTT
  TGCTTACCTGTCCGGTGGGCGGGGGCAGGACGGAAGCCCGGTTATCACCTTCCCTGACTA
  CCCGGCCTTCAGCGAGATTCCGGACAAGGAGTTCCAGAATGTCATGACCTACCTCACCAG
  CATCCCCAGCCTGCAGGACGCTGGCATCGGATTCATCCTGGTGATAGACCGGCGACGGGA
  CAAATGGACCTCCGTGAAGGCGTCCGTCCTGCGCATCGCAGCATCTTTCCCGGCAAACCT
  GCAGCTCGTCCTCGTGCTTCGCCCGACGGGTTTTTTCCAAAGGACTCTCTCCGACATCGC
  TTTCAAATTCAATAGAGATGACTTTAAGATGAAGGTGCCGGTCATAATGCTGAGCTCCGT
  ACCAGACTTACACGGTTACATCGATAAGTCGCAGCTGACCGAGGACCTGGGTGGGACCCT
  GGACTACTGCCACTCCCGGTGGCTGTGCCAGCGCACGGCCATCGAAAGTTTCGCCCTCAT
  GGTGAAGCAGACGGCTCAGATGCTGCAGTCCTTCGGGACCGAGCTGGCTGAAACAGAGCT
  GCCCAATGACGTCCAGTCGACAAGCTCAGTGCTGTGTGCGCACACAGAGAAGAAGGACAA
  GGCGAAGGAGGATTTGAGGCTGGCACTGAAAGAGGGGCACAGTGTCCTGGAGAGCCTCAG
  GGAGCTGCAGGCTGAGGGCTCAGAGCCCAGTGTGAACCAGGACCAGCTTGACAACCAGGC
  CACCGTGCAGAGGCTCCTGGCCCAGCTGAACGAAACCGAGGCTGCCTTCGATGAGTTCTG
  GGCAAAGCATCAGCAGAAACTGGAGCAGTGTCTGCAGCTCCGGCACTTTGAGCAGGGCTT
  CCGGGAGGTCAAAGCCATCTTGGACGCAGCGTCCCAGAAGATAGCAACCTTCACAGACAT
  CGGCAACAGCCTGGCGCATGTGGAGCACCTGCTGAGGGACCTGGCCAGCTTCGAGGAGAA
  ATCAGGCGTGGCCGTGGAGAGGGCCCGGGCCCTGTCTCTGGACGGCGAGCAGCTCATTGG
  GAACAAGCACTACGCGGTAGACTCCATCCGCCCAAAGTGCCAGGAGCTCCGGCACCTCTG
  TGACCAGTTCTCTGCGGAGATCGCAAGGAGGAGGGGGCTGCTCAGCAAGTCCCTGGAGCT
  GCACCGCCGCCTGGAGACGTCCATGAAGTGGTGTGATGAAGGGATTTACCTGCTGGCCTC
  ACAACCTGTGGACAAGTGCCAGTCCCAGGACGGCGCGGAGGCTGCCCTCCAGGAAATCGA
  GAAGTTTTTGGAGACCGGTGCGGAAAATAAGATCCAGGAGCTCAACGCGATTTACAAGGA
  ATACGAATCCATCCTCAACCAAGATCTCATGGAGCACGTGCGAAAGGTCTTCCAGAAGCA
  GGCAAGCATGGAGGAGGTGTTCCACCGCAGGCAGGCCAGCCTGAAGAAGCTGGCGGCCAG
  GCAGACGCGGCCCGTGCAGCCGGTGGCCCCCAGACCCGAGGCACTGGCAAAGTCGCCCTG
  CCCCTCCCCAGGCATTCGGCGAGGCTCTGAGAACTCCAGCTCCGAGGGCGGTGCGCTCCG
  GAGAGGGCCCTACCGGAGGGCCAAGAGTGAGATGAGTGAGAGCCGGCAGGGCCGCGGCTC
  AGCGGGGGAGGAGGAGGAAAGCCTGGCCATCCTGCGCAGGCACGTGATGAGCGAGCTCCT
  GGACACAGAACGGGCCTACGTGGAGGAGCTGCTGTGCGTCCTGGAGGGCTACGCCGCGGA
  GATGGATAACCCACTGATGGCTCACCTCCTGTCAACAGGCCTTCACAACAAGAAGGATGT
  TTTGTTTGGAAACATGGAGGAAATCTATCACTTCCACAACAGGATATTCCTCAGGGAGCT
  GGAAAACTACACTGACTGCCCAGAACTGGTTGGAAGATGCTTTCTGGAGAGGATGGAAGA
  TTTCCAGATCTATGAGAAGTACTGTCAGAACAAGCCCCGCTCTGAGAGCCTGTGGAGACA
  GTGCTCCGACTGCCCGTTTTTCCAGGAATGCCAGAGAAAGCTGGACCACAAGCTGAGCCT
  GGACTCCTACCTGCTGAAGCCAGTGCAGAGGATCACCAAGTACCAGCTGCTGCTCAAGGA
  AATGCTGAAATACAGCAGGAACTGCGAGGGGGCTGAGGACCTGCAGGAGGCGCTGAGCTC
  CATCCTGGGCATCCTGAAGGCCGTGAACGACTCCATGCACCTCATCGCTATCACCGGCTA
  TGACGGGAATCTCGGCGACCTGGGCAAGCTGCTGATGCAGGGCTCGTTCAGCGTCTGGAC
  CGACCACAAGAGGGGCCACACCAAGGTGAAGGAGCTGGCCAGGTTCAAGCCCATGCAGCG
  GCACCTGTTCCTGCACGAGAAGGCAGTGCTCTTCTGCAAGAAGAGGGAGGAGAATGGGGA
  GGGGTATGAGAAAGCTCCCTCCTACAGCTACAAGCAGTCCTTAAACATGGCTGCCGTTGG
  CATTACGGAGAACGTGAAGGGAGATGCTAAGAAGTTCGAGATCTGGTACAACGCGCGCGA
  GGAGGTCTACATCGTCCAGGCGCCAACTCCTGAGATTAAAGCCGCGTGGGTGAATGAAAT
  TCGGAAAGTGCTGACCAGCCAGCTGCAGGCTTGTAGAGAAGCCAGCCAGCACCGGGCGCT
  GGAGCAGTCACAGAGCCTGCCCCTGCCGGCCCCGACCAGCACCAGTCCCTCAAGAGGAAA
  CTCAAGGAACATCAAGAAGCTGGAAGAAAGGAAAACAGACCCCCTAAGCCTGGAGGGATA
  CGTCAGCTCAGCGCCACTGACAAAGCCCCCCGAAAAGGGCAAAGAGCCCTAGGACCCCAC
  AGAAGAGCCCCTCCCTCTCCATTGCTCTGCACCCCTGCATCAGCAAGGCCAGCCCCAGAA
  GGAGCCTCGGCCGAGCGTGCAACCCGGAGCCGCCTTGGGCCCTCCCTGCGACAGCCGGAC
  CCGCCTCCGCATCGGGTTGCGATGCCCTCTGCATAGTTTCTTTCTCTTCCTTCATAGATG
  ACACGGTCACTAGCTCTGCCTCAGAAAGCTCTGCGCTTTCCAGAAAGCGCTTTACCCTGC
  AGGGTTTTGCTAACCTCAAAGGTCAGAAAGGTAAAAGTAGTGCCTGCCCCAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024979 unedited
  NNNGGCAGTTCAAATTTGTATACGACTCATATAGGCCGGCCGCGAATTCGCACGAGGGCT
  GCCCTGCAGAGGCCAGGTCTGCCCAGCAAACCCAGGAAGGTGTGGCGTCCCCGCTTCGCG
  GCCAAGATGGTGCTGGTGCTGCGCCATCCTTTGTGTGCCCGGGAAGGGCGTTCCGGGAGC
  CGGGTCGGGGGCTCCTGACTCGCATTGGGCAGCATGACGGTGCGCCGGCTGTCACTGCTG
  TGCCGGGACCTCTGGGCGCTGTGGCTGCTGCTGAAGGCCGGCGCAGATGAAATCATGCAC
  CAGGACATCGTCCCGCTCTGTGCTGCCGACATCCAGGACCAGCTAAAGAAGCGCTTTGCT
  TACCTGTCCGGTGGGCGGGGGCAGGACGGAAGCCCGGTTATCACCTTCCCTGACTACCCG
  GCCTTCAGCGAGATTCCGGACAAGGAGTTCCAGAATGTCATGACCTACCTCACCAGCATC
  CCCAGCCTGCAGGACGCTGGCATCGGATTCATCCTGGTGATAGACCGGCGACGGGACAAA
  TGGACCTCCGTGAAGGCGTCCGTCCTGCGCATCGCAGCATCTTTCCCGGCAAACCTGCAG
  CTCGTCCTCGTGCTTCGCCCGACGGGTTTTTTCCAAAGGACTCTCTCCGACATCGCTTTC
  AAATTCAATAGAGATGACTTTAAGATGAAGGTGCCGGTCATAATGCTGAGCTCCGTACCA
  GACTTACACGGTTACATCGATAAGTCGCAGCTGACCGAGGACCTGGGTGGGACCCTGGAC
  TACTGCCACTCCCGGTGGCTGTGCCAGCGCACGGCCATCGAAAGTTTCGCCCTCATGGTG
  AAGCAGACGGCTCAGATGCTGCAGTCCTTCGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_024979
• ORF Size: 2955 bp
• Insert Size: 3463
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_024979.2, NP_079255.2
• RefSeq Size: 3463
• RefSeq ORF: 2955
• Locus ID: 23263
• Gene Summary: This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1, resulting in an isoform (b) with a distinct and shorter N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. CCDS Note: The coding region has been updated to represent an alternative splicing pattern that is more supported by the available transcript data.