ARHGEF14 (MCF2L) (NM_024979) Human Untagged Clone

CAT#: SC318509

MCF2L (untagged)-Human MCF.2 cell line derived transforming sequence-like (MCF2L), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCF2L
• Synonyms: ARHGEF14; DBS; OST
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_024979, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACGGTGCGCCGGCTGTCACTGCTGTGCCGGGACCTCTGGGCGCTGTGGCTGCTGCTGAAGGCCGGCG
  CAGATGAAATCATGCACCAGGACATCGTCCCGCTCTGTGCTGCCGACATCCAGGACCAGCTAAAGAAGCG
  CTTTGCTTACCTGTCCGGTGGGCGGGGGCAGGACGGAAGCCCGGTTATCACCTTCCCTGACTACCCGGCC
  TTCAGCGAGATTCCGGACAAGGAGTTCCAGAATGTCATGACCTACCTCACCAGCATCCCCAGCCTGCAGG
  ACGCTGGCATCGGATTCATCCTGGTGATAGACCGGCGACGGGACAAATGGACCTCCGTGAAGGCGTCCGT
  CCTGCGCATCGCAGCATCTTTCCCGGCAAACCTGCAGCTCGTCCTCGTGCTTCGCCCGACGGGTTTTTTC
  CAAAGGACTCTCTCCGACATCGCTTTCAAATTCAATAGAGATGACTTTAAGATGAAGGTGCCGGTCATAA
  TGCTGAGCTCCGTACCAGACTTACACGGTTACATCGATAAGTCGCAGCTGACCGAGGACCTGGGTGGGAC
  CCTGGACTACTGCCACTCCCGGTGGCTGTGCCAGCGCACGGCCATCGAAAGTTTCGCCCTCATGGTGAAG
  CAGACGGCTCAGATGCTGCAGTCCTTCGGGACCGAGCTGGCTGAAACAGAGCTGCCCAATGACGTCCAGT
  CGACAAGCTCAGTGCTGTGTGCGCACACAGAGAAGAAGGACAAGGCGAAGGAGGATTTGAGGCTGGCACT
  GAAAGAGGGGCACAGTGTCCTGGAGAGCCTCAGGGAGCTGCAGGCTGAGGGCTCAGAGCCCAGTGTGAAC
  CAGGACCAGCTTGACAACCAGGCCACCGTGCAGAGGCTCCTGGCCCAGCTGAACGAAACCGAGGCTGCCT
  TCGATGAGTTCTGGGCAAAGCATCAGCAGAAACTGGAGCAGTGTCTGCAGCTCCGGCACTTTGAGCAGGG
  CTTCCGGGAGGTCAAAGCCATCTTGGACGCAGCGTCCCAGAAGATAGCAACCTTCACAGACATCGGCAAC
  AGCCTGGCGCATGTGGAGCACCTGCTGAGGGACCTGGCCAGCTTCGAGGAGAAATCAGGCGTGGCCGTGG
  AGAGGGCCCGGGCCCTGTCTCTGGACGGCGAGCAGCTCATTGGGAACAAGCACTACGCGGTAGACTCCAT
  CCGCCCAAAGTGCCAGGAGCTCCGGCACCTCTGTGACCAGTTCTCTGCGGAGATCGCAAGGAGGAGGGGG
  CTGCTCAGCAAGTCCCTGGAGCTGCACCGCCGCCTGGAGACGTCCATGAAGTGGTGTGATGAAGGGATTT
  ACCTGCTGGCCTCACAACCTGTGGACAAGTGCCAGTCCCAGGACGGCGCGGAGGCTGCCCTCCAGGAAAT
  CGAGAAGTTTTTGGAGACCGGTGCGGAAAATAAGATCCAGGAGCTCAACGCGATTTACAAGGAATACGAA
  TCCATCCTCAACCAAGATCTCATGGAGCACGTGCGAAAGGTCTTCCAGAAGCAGGCAAGCATGGAGGAGG
  TGTTCCACCGCAGGCAGGCCAGCCTGAAGAAGCTGGCGGCCAGGCAGACGCGGCCCGTGCAGCCGGTGGC
  CCCCAGACCCGAGGCACTGGCAAAGTCGCCCTGCCCCTCCCCAGGCATTCGGCGAGGCTCTGAGAACTCC
  AGCTCCGAGGGCGGTGCGCTCCGGAGAGGGCCCTACCGGAGGGCCAAGAGTGAGATGAGTGAGAGCCGGC
  AGGGCCGCGGCTCAGCGGGGGAGGAGGAGGAAAGCCTGGCCATCCTGCGCAGGCACGTGATGAGCGAGCT
  CCTGGACACAGAACGGGCCTACGTGGAGGAGCTGCTGTGCGTCCTGGAGGGCTACGCCGCGGAGATGGAT
  AACCCACTGATGGCTCACCTCCTGTCAACAGGCCTTCACAACAAGAAGGATGTTTTGTTTGGAAACATGG
  AGGAAATCTATCACTTCCACAACAGGATATTCCTCAGGGAGCTGGAAAACTACACTGACTGCCCAGAACT
  GGTTGGAAGATGCTTTCTGGAGAGGATGGAAGATTTCCAGATCTATGAGAAGTACTGTCAGAACAAGCCC
  CGCTCTGAGAGCCTGTGGAGACAGTGCTCCGACTGCCCGTTTTTCCAGGAATGCCAGAGAAAGCTGGACC
  ACAAGCTGAGCCTGGACTCCTACCTGCTGAAGCCAGTGCAGAGGATCACCAAGTACCAGCTGCTGCTCAA
  GGAAATGCTGAAATACAGCAGGAACTGCGAGGGGGCTGAGGACCTGCAGGAGGCGCTGAGCTCCATCCTG
  GGCATCCTGAAGGCCGTGAACGACTCCATGCACCTCATCGCTATCACCGGCTATGACGGGAATCTCGGCG
  ACCTGGGCAAGCTGCTGATGCAGGGCTCGTTCAGCGTCTGGACCGACCACAAGAGGGGCCACACCAAGGT
  GAAGGAGCTGGCCAGGTTCAAGCCCATGCAGCGGCACCTGTTCCTGCACGAGAAGGCAGTGCTCTTCTGC
  AAGAAGAGGGAGGAGAATGGGGAGGGGTATGAGAAAGCTCCCTCCTACAGCTACAAGCAGTCCTTAAACA
  TGGCTGCCGTTGGCATTACGGAGAACGTGAAGGGAGATGCTAAGAAGTTCGAGATCTGGTACAACGCGCG
  CGAGGAGGTCTACATCGTCCAGGCGCCAACTCCTGAGATTAAAGCCGCGTGGGTGAATGAAATTCGGAAA
  GTGCTGACCAGCCAGCTGCAGGCTTGTAGAGAAGCCAGCCAGCACCGGGCGCTGGAGCAGTCACAGAGCC
  TGCCCCTGCCGGCCCCGACCAGCACCAGTCCCTCAAGAGGAAACTCAAGGAACATCAAGAAGCTGGAAGA
  AAGGAAAACAGACCCCCTAAGCCTGGAGGGATACGTCAGCTCAGCGCCACTGACAAAGCCCCCCGAAAAG
  GGCAAAGGTTGGAGCAAAACGTCCCACTCACTGGAGGCACCTGAGGACGACGGGGGCTGGTCAAGTGCAG
  AGGAGCAGATTAACTCGTCCGACGCAGAGGAGGACGGCGGGTTGGGCCCCAAGAAGCTGGTTCCAGGTAA
  ATACACGGTCGTGGCGGACCACGAGAAGGGAGGCCCCGATGCGCTGCGCGTGAGGAGCGGGGACGTGGTG
  GAGCTGGTGCAGGAGGGCGACGAGGGCCTCTGGTACGTCAGGGACCCGACCACTGGCAAGGAGGGCTGGG
  TGCCGGCCAGCAGCCTGTCCGTCCGGCTCGGCCCGTCCGGCTCGGCCCAGTGCCTGAGCAGCTCAGAGTC
  GAGCCCGGGGTCGGCCGTGCTGAGCAACTCGTCCAGCTGCAGCGAGGGCGGCCAGGCCCCCTTCTCCGAC
  CTGCAGGGGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_024979
• ORF Size: 3372 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_024979.4, NP_079255.4
• RefSeq Size: 6456
• RefSeq ORF: 3372
• Locus ID: 23263
• Gene Summary: This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1, resulting in an isoform (b) with a distinct and shorter N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. CCDS Note: The coding region has been updated to represent an alternative splicing pattern that is more supported by the available transcript data.