ACMSD (NM_138326) Human Untagged Clone

CAT#: SC123129

ACMSD (untagged)-Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACMSD
• Synonyms: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; aminocarboxymuconate semialdehyde decarboxylase; OTTHUMP00000162500
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_138326 edited
  GGGGAGTTTTCACAAAGGTCTCTTGATATCAAAACTTCTTTCCTTGCATGCTTCTCTGAT
  CCTGTGGAGATGAAAATTGACATCCATAGTCATATTCTACCAAAAGAATGGCCAGATCTA
  AAAAAGACCCTGAGACAAGGATTCAGATGCAAGTAGTTTGCTTTGGAGGTGATCCCAGGA
  AACACCAGTAGAGTGAGGAAGTGAGACAGGGAAAACAGGGCAGCCAGTGAAAGAGGTTTG
  GCTACGGAGGCTGGGTGCAGCTCCAACACCACAGCAAGGGAGAAGCAAAGTTGTTGAAAG
  ATGGGAAAGTCTTCAGAGTGGTGCGAGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAG
  AAATGGACCAAAAAGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAAC
  GACCTTGCCAGCACCGTTGTGAGCTACCCCAGGAGGTTCGTGGGTCTGGGGACGTTGCCC
  ATGCAGGCCCCTGAGCTGGCGGTCAAGGAGATGGAGCGCTGTGTGAAAGAGCTGGGCTTT
  CCCGGGGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTT
  CCTGTCTATGCGGCAGCCGAAAGGCTGAAGTGTTCCCTGTTCGTGCATCCCTGGGACATG
  CAGATGGATGGACGAATGGCCAAATACTGGCTCCCTTGGCTTGTAGGAATGCCAGCAGAG
  ACCACCATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAAACTG
  AAAGTGTGTTTCGCACATGGTGGTGGTGCCTTCCCCTTCACAGTGGGAAGAATCTCCCAT
  GGATTCAGCATGCGCCCAGATCTGTGTGCCCAGGACAACCCCATGAACCCGAAGAAATAC
  CTTGGTTCCTTTTACACAGATGCTTTGGTTCATGATCCTCTGTCCCTCAAGCTGTTAACA
  GATGTCATAGGAAAGGATAAAGTCATTTTGGGAACCGATTACCCCTTTCCACTAGGTGAG
  CTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAA
  CTCAAAGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTG
  AATTTACTACAAAGGCAAACTTTCAAAAGGATATCTCATTTTTGTTTCTAAATATGTATC
  AACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATA
  TCCTAAATTATTCATAATAAAAATGATTTGTAAGTGTTTTCATTCTGAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138326 unedited
  CACGTCAAATATTGTATACGACTCATATAGGGCGGCCGCGAATTCGCCATTACGGCCGGG
  GAGTTTTCACAAAGGTCTCTTGATATCAAAACTTCTTTCCTTGCATGCTTCTCTGATCCT
  GTGGAGATGAAAATTGACATCCATAGTCATATTCTACCAAAAGAATGGCCAGATCTAAAA
  AAGACCCTGAGACAAGGATTCAGATGCAAGTAGTTTGCTTTGGAGGTGATCCCAGGAAAC
  ACCAGTAGAGTGAGGAAGTGAGACAGGGAAAACAGGGCAGCCAGTGAAAGAGGTTTGGCT
  ACGGAGGCTGGGTGCAGCTCCAACACCACAGCAAGGGAGAAGCAAAGTTGTTGAAAGATG
  GGAAAGTCTTCAGAGTGGTGCGAGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAGAAA
  TGGACCAAAAAGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAACGAC
  CTTGCCAGCACCGTTGTGAGCTACCCCAGGAGGTTCGTGGGTCTGGGGACGTTGCCCATG
  CAGGCCCCTGAGCTGGCGGTCAAGGAGATGGAGCGCTGTGTGAAAGAGCTGGGCTTTCCC
  GGNGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTTCCT
  GTCTATGCGGCAGCCGAAAGGCTGAAGTGTTCCCTGTTCGTGCATCCCTGGGACATGCAG
  ATGGATGGACGAATGGCCAAATACTGGCTCCCTTGGCTTGTANGAATGCCAGCAGAGACC
  ACCATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAACTGAAAG
  TGTGTTTCCACATGGTGGTGGTGCTTTCCCCTTCCAGTGGGAAGATCTCCATGGATTCGC
  ATGCGCCCAGTCTGTGC
  
• Restriction Sites: Please inquire
• ACCN: NM_138326
• ORF Size: 1278 bp
• Insert Size: 1337
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_138326.1, NP_612199.1
• RefSeq Size: 1337
• RefSeq ORF: 1278
• Locus ID: 130013
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Tryptophan metabolism
• Gene Summary: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS. [supplied by OMIM, Oct 2004]
  Transcript Variant: This variant (1) encodes the longer isoform (1).