RANTES (CCL5) (BC003528) Human Untagged Clone

CAT#: SC123770

(untagged)-Homo sapiens, clone MGC:10782 IMAGE:3608303, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCL5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC003528 edited
  CTGACTTGGACCCTTCTTTGGAGAGGAGCAGGAAGGACCTCCAAGGTGAAGGGGTGAGGG
  GATGCCAGGTTTCTGAGCAGTGGGCTGGCCCTGGCATAATGCTATGGTGTTGAACGACCA
  CAGCTCACAGGTCCCTCATGGAGGCCTGAGCCCTTCAATGCCAGGACTTGGACCTGCCAT
  TCTGGTCAGCGCCACGGCTGTGGACACAGCCATCTGGTCCCCCCAACGGGATGGAGCAGG
  CCTGCCATCTAGATCCTGCCAGGGGCCGAGGAGGCGAGAGTTGCTAGGGAAGTGATTAGT
  TTACCCTTAAGTAAGTACCTGAGCCTGTTTCAGTGATCAATAAAATCAGCAATGTTAGCC
  GGGAATGGTGGCTTATGACTGTAATCCCAGCATTTCAGGAGGCTGAAGCCGGAGGATCGC
  TTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCTCTACTAAAA
  TATACAAAAATTAGCCAGGTGAGGTGGCATGTGCCTGTAGTCCCAGGTACTCAGGAGGCT
  GAGGTAGGAGGATCACTGATGTATGTGTGTATACACACACACATGTATTTGTAGATTGGG
  GGTCCCCAAGACCACCCTTAGGTTTGACACCTTGCTAGAAGAACTCAGAGAATGTATTAA
  AAACTATTATGCTCATGGTCATGGTTTATTACAGCAAAAAGATACAGATTAGGATGGGTG
  CGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGAGGGAGGATCACTTGAG
  GTCAGGAGTTCGAGACCAGCCTGACCAACATGATCAAACCCCAACTCTACTAAAAACCCA
  AAAATTAGCCGGGCATAGTGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCA
  GAAGAATCGCTTGAACCCAGGAGGCACAGATTGCAATGAGCCTAGATTGTGCCTCTGTAC
  TCCAGCCTGGATGACAGAGTGAGACTCAGTCTCAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC003528 unedited
  NNNCCGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGAC
  TTGGACCCTTCTTTGGAGAGGAGCAGGAAGGACCTCCAAGGTGAAGGGGTGAGGGGATGC
  CAGGTTTCTGAGCAGTGGGCTGGCCCTGGCATAATGCTATGGTGTTGAACGACCACAGCT
  CACAGGTCCCTCATGGAGGCCTGAGCCCTTCAATGCCAGGACTTGGACCTGCCATTCTGG
  TCAGCGCCACGGCTGTGGACACAGCCATCTGGTCCCCCCAACGGGATGGAGCAGGCCTGC
  CATCTAGATCCTGCCAGGGGCCGAGGAGGCGAGAGTTGCTAGGGAAGTGATTAGTTTACC
  CTTAAGTAAGTACCTGAGCCTGTTTCAGTGATCAATAAAATCAGCAATGTTAGCCGGGAA
  TGGTGGCTTATGACTGTAATCCCAGCATTTCAGGAGGCTGAAGCCGGAGGATCGCTTGAG
  CCCAGGAGTTTGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCTCTACTAAAATATAC
  AAAAATTAGCCAGGTGAGGTGGCATGTGCCTGTAGTCCCAGGTACTCAGGAGGCTGAGGT
  AGGAGGATCACTGATGTATGTGTGTATACACACACACATGTATTTGTAGATTGGGGGTCC
  CCAAGACCACCCTTAGGTTTGACACCTTGCTAGAAGAACTCAGAGAATGTATTAAAAACT
  ATTATGCTCATGGTCATGGTTTATTACAGCANANAGATACAGATTANNGATGGGTGCGGG
  CTATGCCCCGGTGGAATCCCANCACTTTGGGAGGCTGAGGAGGGGAGGATCACTTGAGTC
  AGNAGNTTCCNGGAACCACCCTGAACAACCTGATTCAAACCCACCTCTACTAAAAACCCC
  AAAA
  
• Restriction Sites: Please inquire
• ACCN: BC003528
• Insert Size: 1018 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC003528.1
• RefSeq Size: 1018 bp
• Locus ID: 6352
• Cytogenetics: 17q12
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway
• Gene Summary: 'This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]'