RANTES (CCL5) (BC003528) Human Untagged Clone

CAT#: SC123770

(untagged)-Homo sapiens, clone MGC:10782 IMAGE:3608303, complete cds


Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CCL5
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for BC003528 edited
CTGACTTGGACCCTTCTTTGGAGAGGAGCAGGAAGGACCTCCAAGGTGAAGGGGTGAGGG
GATGCCAGGTTTCTGAGCAGTGGGCTGGCCCTGGCATAATGCTATGGTGTTGAACGACCA
CAGCTCACAGGTCCCTCATGGAGGCCTGAGCCCTTCAATGCCAGGACTTGGACCTGCCAT
TCTGGTCAGCGCCACGGCTGTGGACACAGCCATCTGGTCCCCCCAACGGGATGGAGCAGG
CCTGCCATCTAGATCCTGCCAGGGGCCGAGGAGGCGAGAGTTGCTAGGGAAGTGATTAGT
TTACCCTTAAGTAAGTACCTGAGCCTGTTTCAGTGATCAATAAAATCAGCAATGTTAGCC
GGGAATGGTGGCTTATGACTGTAATCCCAGCATTTCAGGAGGCTGAAGCCGGAGGATCGC
TTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCTCTACTAAAA
TATACAAAAATTAGCCAGGTGAGGTGGCATGTGCCTGTAGTCCCAGGTACTCAGGAGGCT
GAGGTAGGAGGATCACTGATGTATGTGTGTATACACACACACATGTATTTGTAGATTGGG
GGTCCCCAAGACCACCCTTAGGTTTGACACCTTGCTAGAAGAACTCAGAGAATGTATTAA
AAACTATTATGCTCATGGTCATGGTTTATTACAGCAAAAAGATACAGATTAGGATGGGTG
CGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGAGGGAGGATCACTTGAG
GTCAGGAGTTCGAGACCAGCCTGACCAACATGATCAAACCCCAACTCTACTAAAAACCCA
AAAATTAGCCGGGCATAGTGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCA
GAAGAATCGCTTGAACCCAGGAGGCACAGATTGCAATGAGCCTAGATTGTGCCTCTGTAC
TCCAGCCTGGATGACAGAGTGAGACTCAGTCTCAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for BC003528 unedited
NNNCCGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGAC
TTGGACCCTTCTTTGGAGAGGAGCAGGAAGGACCTCCAAGGTGAAGGGGTGAGGGGATGC
CAGGTTTCTGAGCAGTGGGCTGGCCCTGGCATAATGCTATGGTGTTGAACGACCACAGCT
CACAGGTCCCTCATGGAGGCCTGAGCCCTTCAATGCCAGGACTTGGACCTGCCATTCTGG
TCAGCGCCACGGCTGTGGACACAGCCATCTGGTCCCCCCAACGGGATGGAGCAGGCCTGC
CATCTAGATCCTGCCAGGGGCCGAGGAGGCGAGAGTTGCTAGGGAAGTGATTAGTTTACC
CTTAAGTAAGTACCTGAGCCTGTTTCAGTGATCAATAAAATCAGCAATGTTAGCCGGGAA
TGGTGGCTTATGACTGTAATCCCAGCATTTCAGGAGGCTGAAGCCGGAGGATCGCTTGAG
CCCAGGAGTTTGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCTCTACTAAAATATAC
AAAAATTAGCCAGGTGAGGTGGCATGTGCCTGTAGTCCCAGGTACTCAGGAGGCTGAGGT
AGGAGGATCACTGATGTATGTGTGTATACACACACACATGTATTTGTAGATTGGGGGTCC
CCAAGACCACCCTTAGGTTTGACACCTTGCTAGAAGAACTCAGAGAATGTATTAAAAACT
ATTATGCTCATGGTCATGGTTTATTACAGCANANAGATACAGATTANNGATGGGTGCGGG
CTATGCCCCGGTGGAATCCCANCACTTTGGGAGGCTGAGGAGGGGAGGATCACTTGAGTC
AGNAGNTTCCNGGAACCACCCTGAACAACCTGATTCAAACCCACCTCTACTAAAAACCCC
AAAA
Restriction Sites Please inquire     
ACCN BC003528
Insert Size 1018 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq BC003528.1
RefSeq Size 1018 bp
Locus ID 6352
Cytogenetics 17q12
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway
Gene Summary 'This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]'

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