KCNMB3 (NM_014407) Human Untagged Clone

CAT#: SC123923

KCNMB3 (untagged)-Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNMB3
• Synonyms: BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMBL; SLO-BETA-3; SLOBETA3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014407, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACTTTTCACCAAGCTCTGAACTGGGATTTCATTTTGTTGCATTCATCCTGCTCACGAGACACAGGA
  CAGCCTTTCCTGCCTCAGGGAAGAAGAGAGAGACAGACTACAGTGATGGAGACCCACTAGATGTGCACAA
  GAGGCTGCCATCCAGTGCTGGAGAGGACCGAGCCGTGATGCTGGGGTTTGCCATGATGGGCTTCTCAGTC
  CTAATGTTCTTCTTGCTCGGAACAACCATTCTAAAGCCTTTTATGCTCAGCATTCAGAGAGAAGAATCGA
  CCTGCACTGCCATCCACACAGATATCATGGACGACTGGCTGGACTGTGCCTTCACCTGTGGTGTGCACTG
  CCACGGTCAGGGGAAGTACCCGTGTCTTCAGGTGTTTGTGAACCTCAGCCATCCAGGTCAGAAAGCTCTC
  CTACATTATAATGAAGAGGCTGTCCAGATAAATCCCAAGTGCTTTTACACACCTAAGTGCCACCAAGATA
  GAAATGATTTGCTCAACAGTGCTCTGGACATAAAAGAATTCTTCGATCACAAAAATGGAACCCCCTTTTC
  ATGCTTCTACAGTCCAGCCAGCCAATCTGAAGATGTCATTCTTATAAAAAAGTATGACCAAATGGCTATC
  TTCCACTGTTTATTTTGGCCTTCACTGACTCTGCTAGGTGGTGCCCTGATTGTTGGCATGGTGAGATTAA
  CACAACACCTGTCCTTACTGTGTGAAAAATATAGCACTGTAGTCAGAGATGAGGTAGGTGGAAAAGTACC
  TTATATAGAACAGCATCAGTTCAAACTGTGCATTATGAGGAGGAGCAAAGGAAGAGCAGAGAAATCTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014407 unedited
  CCACTTTAGCAGTCCCCATCGTCATAGAGAGAGATGAAGAAATATTTTGGACACTTATGC
  ATAACCATGAGTCTACCAGAAGAATTTATAAAGAACCCTAGATATCCAACCACCCATTCC
  AACTTCATAATTCTGACTGGACTGCGCACTGGCCACAAATTCTGGTGGTGGATATGCTGC
  CTTTCCAACAGGTGAATATGAAATAATAAGTCAAACCCTGTTCAAGACGCTGTTAATTCC
  AAATGGCAACTTTTTGACTCATTCTTTTCCACTCACAATCAATTTACACTCACAACACAC
  CTCTCTCACCCTCCACTCAACCCTCCCCTCTCCCATTCCTCCTTCCCTCATACCCTATCC
  CATCCAACCGTCACACCTATCATCAGCTCTCACTCAACAACTCAACCCTCGTCACCCCAT
  CTACCACTACATCAACACTCATTCTACATTAACCCCCTACCTATCACATCCTTATCCTCC
  TCGCATCTCTCCAGTCACTCCTCTCCTATATCACACTGACCGATCCTCCATAGTTCCGTA
  ACTCCTACAACCCCGTATAATCTCACGTCTACCTTAGAAGTATGGCACTAACATATGCTG
  TCGTTCATATGACACTCCACTACCACTACTCGTATTATCAATATCGTCACACTCATACCC
  TACATTCACATATGCACCCTACCATCGATCACAATATATCTCTCTATCTGTGCTATCGCA
  CCATATGTGATGCCTCAGCATACTATGTATCTCTGAGANATTCTCTGCGTATTCTCTCTA
  ACGCTATCCTACTGCATATGTCACTACACATGTATAGCACTATGTAATCCACACGTCTAC
  GACACATANGCTCACGATCTCTAACGCCTCTCTCTTAGTCGATATAGATTATCCACACAC
  ACACAATACTCAGTATCCCTACTTCATAGCTATCATCGTCAAAGCTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014407
• ORF Size: 840 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014407.3, NP_055222.3
• RefSeq Size: 1492
• RefSeq ORF: 840
• Locus ID: 27094
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Protein Pathways: Vascular smooth muscle contraction
• Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]
  Transcript Variant: This variant (4) encodes the longest isoform (d).